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Volumn , Issue , 2014, Pages 3-28

CNS barriers in neurotrauma

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EID: 84939936616     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4614-8690-9_1     Document Type: Chapter
Times cited : (2)

References (179)
  • 1
    • 33646516853 scopus 로고    scopus 로고
    • Evaluation of pharmacological treatment strategies in traumatic brain injury
    • Marklund N, Bakshi A, Castelbuono DJ et al (2006) Evaluation of pharmacological treatment strategies in traumatic brain injury. Curr Pharm Des 12:1645-1680
    • (2006) Curr Pharm Des , vol.12 , pp. 1645-1680
    • Marklund, N.1    Bakshi, A.2    Castelbuono, D.J.3
  • 2
    • 33847323914 scopus 로고    scopus 로고
    • Neuroprotection in traumatic brain injury: a complex struggle against the biology of nature
    • Schouten JW (2007) Neuroprotection in traumatic brain injury: a complex struggle against the biology of nature. Curr Opin Crit Care 13:134-142
    • (2007) Curr Opin Crit Care , vol.13 , pp. 134-142
    • Schouten, J.W.1
  • 3
    • 33845207898 scopus 로고    scopus 로고
    • Review of treatment trials in human spinal cord injury: issues, difficulties, and recommendations
    • discussion 982-957
    • Tator CH (2006) Review of treatment trials in human spinal cord injury: issues, difficulties, and recommendations. Neurosurgery 59:957-982, discussion 982-957
    • (2006) Neurosurgery , vol.59 , pp. 957-982
    • Tator, C.H.1
  • 4
    • 63849186608 scopus 로고    scopus 로고
    • Protection and repair of the injured spinal cord: a review of completed, ongoing, and planned clinical trials for acute spinal cord injury
    • Hawryluk GW, Rowland J, Kwon BK et al (2008) Protection and repair of the injured spinal cord: a review of completed, ongoing, and planned clinical trials for acute spinal cord injury. Neurosurg Focus 25:E14
    • (2008) Neurosurg Focus , vol.25 , pp. E14
    • Hawryluk, G.W.1    Rowland, J.2    Kwon, B.K.3
  • 6
    • 57549112353 scopus 로고    scopus 로고
    • Metalloproteinase expression in monocytes and macrophages and its relationship to atherosclerotic plaque instability
    • Newby AC (2008) Metalloproteinase expression in monocytes and macrophages and its relationship to atherosclerotic plaque instability. Arterioscler Thromb Vasc Biol 28:2108-2114
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 2108-2114
    • Newby, A.C.1
  • 7
    • 0032530520 scopus 로고    scopus 로고
    • Role of the CNS microvascular pericyte in the blood-brain barrier
    • Balabanov R, Dore-Duffy P (1998) Role of the CNS microvascular pericyte in the blood-brain barrier. J Neurosci Res 53:637-644
    • (1998) J Neurosci Res , vol.53 , pp. 637-644
    • Balabanov, R.1    Dore-Duffy, P.2
  • 8
    • 77954394706 scopus 로고    scopus 로고
    • The perivascular astroglial sheath provides a complete covering of the brain microvessels: an electron microscopic 3D reconstruction
    • Mathiisen TM, Lehre KP, Danbolt NC et al (2010) The perivascular astroglial sheath provides a complete covering of the brain microvessels: an electron microscopic 3D reconstruction. Glia 58:1094-1103
    • (2010) Glia , vol.58 , pp. 1094-1103
    • Mathiisen, T.M.1    Lehre, K.P.2    Danbolt, N.C.3
  • 9
    • 0026073369 scopus 로고
    • Microglial cells are a component of the perivascular glia limitans
    • Lassmann H, Zimprich F, Vass K et al (1991) Microglial cells are a component of the perivascular glia limitans. J Neurosci Res 28:236-243
    • (1991) J Neurosci Res , vol.28 , pp. 236-243
    • Lassmann, H.1    Zimprich, F.2    Vass, K.3
  • 10
    • 29244463365 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions at the blood-brain barrier
    • Abbott NJ, Rönnbäck L, Hansson E (2006) Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci 7:41-53
    • (2006) Nat Rev Neurosci , vol.7 , pp. 41-53
    • Abbott, N.J.1    Rönnbäck, L.2    Hansson, E.3
  • 11
    • 80055014830 scopus 로고    scopus 로고
    • Central nervous system pericytes in health and disease
    • Winkler EA, Bell RD, Zlokovic BV (2011) Central nervous system pericytes in health and disease. Nat Neurosci 14:1398-1405
    • (2011) Nat Neurosci , vol.14 , pp. 1398-1405
    • Winkler, E.A.1    Bell, R.D.2    Zlokovic, B.V.3
  • 13
    • 78649487239 scopus 로고    scopus 로고
    • Pericytes are required for blood-brain barrier integrity during embryogenesis
    • Daneman R, Zhou L, Kebede AA et al (2010) Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature 468:562-566
    • (2010) Nature , vol.468 , pp. 562-566
    • Daneman, R.1    Zhou, L.2    Kebede, A.A.3
  • 14
    • 78649467527 scopus 로고    scopus 로고
    • Pericytes regulate the blood-brain barrier
    • Armulik A, Genové G, Mäe M et al (2010) Pericytes regulate the blood-brain barrier. Nature 468:557-561
    • (2010) Nature , vol.468 , pp. 557-561
    • Armulik, A.1    Genové, G.2    Mäe, M.3
  • 15
    • 84867083056 scopus 로고    scopus 로고
    • Blood-spinal cord barrier pericyte reductions contribute to increased capillary permeability
    • Winkler EA, Sengillo JD, Bell RD et al (2012) Blood-spinal cord barrier pericyte reductions contribute to increased capillary permeability. J Cereb Blood Flow Metab 32:1841-1852
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 1841-1852
    • Winkler, E.A.1    Sengillo, J.D.2    Bell, R.D.3
  • 16
    • 33746286891 scopus 로고    scopus 로고
    • Isolation and culture of microvascular endothelial cells from murine spinal cord
    • Ge S, Pachter JS (2006) Isolation and culture of microvascular endothelial cells from murine spinal cord. J Neuroimmunol 177:209-214
    • (2006) J Neuroimmunol , vol.177 , pp. 209-214
    • Ge, S.1    Pachter, J.S.2
  • 17
    • 0029382290 scopus 로고
    • Selective permeability of [3H]-D-mannitol and [14C]-carboxyl-inulin across the blood-brain barrier and blood-spinal cord barrier in the rabbit
    • Prockop LD, Naidu KA, Binard JE et al (1995) Selective permeability of [3H]-D-mannitol and [14C]-carboxyl-inulin across the blood-brain barrier and blood-spinal cord barrier in the rabbit. J Spinal Cord Med 18:221-226
    • (1995) J Spinal Cord Med , vol.18 , pp. 221-226
    • Prockop, L.D.1    Naidu, K.A.2    Binard, J.E.3
  • 18
    • 84864565346 scopus 로고    scopus 로고
    • ABC transporter function and regulation at the blood-spinal cord barrier
    • Campos CR, Schröter C, Wang X et al (2012) ABC transporter function and regulation at the blood-spinal cord barrier. J Cereb Blood Flow Metab 32:1559-1566
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 1559-1566
    • Campos, C.R.1    Schröter, C.2    Wang, X.3
  • 19
    • 0033948974 scopus 로고    scopus 로고
    • Choroid plexus in the central nervous system: biology and physiopathology
    • Strazielle N, Ghersi-Egea JF (2000) Choroid plexus in the central nervous system: biology and physiopathology. J Neuropathol Exp Neurol 59:561-574
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 561-574
    • Strazielle, N.1    Ghersi-Egea, J.F.2
  • 20
    • 84872196363 scopus 로고    scopus 로고
    • Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier
    • Kratzer I, Vasiljevic A, Rey C et al (2012) Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier. Histochem Cell Biol 138:861-879
    • (2012) Histochem Cell Biol , vol.138 , pp. 861-879
    • Kratzer, I.1    Vasiljevic, A.2    Rey, C.3
  • 21
    • 0037115724 scopus 로고    scopus 로고
    • Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells
    • Amasheh S, Meiri N, Gitter AH et al (2002) Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells. J Cell Sci 115:4969-4976
    • (2002) J Cell Sci , vol.115 , pp. 4969-4976
    • Amasheh, S.1    Meiri, N.2    Gitter, A.H.3
  • 22
    • 0025126177 scopus 로고
    • A morphometric study on the development of the lateral ventricle choroid plexus, choroid plexus capillaries and ventricular ependyma in the rat
    • Keep RF, Jones HC (1990) A morphometric study on the development of the lateral ventricle choroid plexus, choroid plexus capillaries and ventricular ependyma in the rat. Brain Res Dev Brain Res 56:47-53
    • (1990) Brain Res Dev Brain Res , vol.56 , pp. 47-53
    • Keep, R.F.1    Jones, H.C.2
  • 23
    • 0028364769 scopus 로고
    • Postnatal developmental changes in blood flow to choroid plexuses and cerebral cortex of the rat
    • Szmydynger-Chodobska J, Chodobski A, Johanson CE (1994) Postnatal developmental changes in blood flow to choroid plexuses and cerebral cortex of the rat. Am J Physiol 266:R1488-R1492
    • (1994) Am J Physiol , vol.266 , pp. R1488-R1492
    • Szmydynger-Chodobska, J.1    Chodobski, A.2    Johanson, C.E.3
  • 24
    • 53149117869 scopus 로고    scopus 로고
    • Differential expression of the multidrug resistance-related proteins ABCB1 and ABCC1 between blood-brain interfaces
    • Gazzin S, Strazielle N, Schmitt C et al (2008) Differential expression of the multidrug resistance-related proteins ABCB1 and ABCC1 between blood-brain interfaces. J Comp Neurol 510:497-507
    • (2008) J Comp Neurol , vol.510 , pp. 497-507
    • Gazzin, S.1    Strazielle, N.2    Schmitt, C.3
  • 25
    • 4644239463 scopus 로고    scopus 로고
    • Immunolocalization of the proton-coupled oligopeptide transporter PEPT2 in developing rat brain
    • Shen H, Smith DE, Keep RF et al (2004) Immunolocalization of the proton-coupled oligopeptide transporter PEPT2 in developing rat brain. Mol Pharm 1:248-256
    • (2004) Mol Pharm , vol.1 , pp. 248-256
    • Shen, H.1    Smith, D.E.2    Keep, R.F.3
  • 26
    • 4344632950 scopus 로고    scopus 로고
    • Mrp4 confers resistance to topotecan and protects the brain from chemotherapy
    • Leggas M, Adachi M, Scheffer GL et al (2004) Mrp4 confers resistance to topotecan and protects the brain from chemotherapy. Mol Cell Biol 24:7612-7621
    • (2004) Mol Cell Biol , vol.24 , pp. 7612-7621
    • Leggas, M.1    Adachi, M.2    Scheffer, G.L.3
  • 27
    • 48249108682 scopus 로고    scopus 로고
    • Classification of traumatic brain injury for targeted therapies
    • Saatman KE, Duhaime AC, Bullock R et al (2008) Classification of traumatic brain injury for targeted therapies. J Neurotrauma 25:719-738
    • (2008) J Neurotrauma , vol.25 , pp. 719-738
    • Saatman, K.E.1    Duhaime, A.C.2    Bullock, R.3
  • 28
    • 0027964581 scopus 로고
    • Early microvascular and neuronal consequences of traumatic brain injury: a light and electron microscopic study in rats
    • Dietrich WD, Alonso O, Halley M (1994) Early microvascular and neuronal consequences of traumatic brain injury: a light and electron microscopic study in rats. J Neurotrauma 11:289-301
    • (1994) J Neurotrauma , vol.11 , pp. 289-301
    • Dietrich, W.D.1    Alonso, O.2    Halley, M.3
  • 29
    • 0024515595 scopus 로고
    • Distribution and time course of protein extravasation in the rat spinal cord after contusive injury
    • Noble LJ, Wrathall JR (1989) Distribution and time course of protein extravasation in the rat spinal cord after contusive injury. Brain Res 482:57-66
    • (1989) Brain Res , vol.482 , pp. 57-66
    • Noble, L.J.1    Wrathall, J.R.2
  • 30
    • 0036123293 scopus 로고    scopus 로고
    • Progressive hemorrhage after head trauma:predictors and consequences of the evolving injury
    • Oertel M, Kelly DF, McArthur D et al (2002) Progressive hemorrhage after head trauma:predictors and consequences of the evolving injury. J Neurosurg 96:109-116
    • (2002) J Neurosurg , vol.96 , pp. 109-116
    • Oertel, M.1    Kelly, D.F.2    McArthur, D.3
  • 31
    • 84856469883 scopus 로고    scopus 로고
    • Hemorrhagic progression of a contusion after traumatic brain injury: a review
    • Kurland D, Hong C, Aarabi B et al (2012) Hemorrhagic progression of a contusion after traumatic brain injury: a review. J Neurotrauma 29:19-31
    • (2012) J Neurotrauma , vol.29 , pp. 19-31
    • Kurland, D.1    Hong, C.2    Aarabi, B.3
  • 32
    • 34547691350 scopus 로고    scopus 로고
    • Endothelial sulfonylurea receptor 1- regulated NCCa-ATP channels mediate progressive hemorrhagic necrosis following spinal cord injury
    • Simard JM, Tsymbalyuk O, Ivanov A et al (2007) Endothelial sulfonylurea receptor 1- regulated NCCa-ATP channels mediate progressive hemorrhagic necrosis following spinal cord injury. J Clin Invest 117:2105-2113
    • (2007) J Clin Invest , vol.117 , pp. 2105-2113
    • Simard, J.M.1    Tsymbalyuk, O.2    Ivanov, A.3
  • 33
    • 74949128970 scopus 로고    scopus 로고
    • Key role of sulfonylurea receptor 1 in progressive secondary hemorrhage after brain contusion
    • Simard JM, Kilbourne M, Tsymbalyuk O et al (2009) Key role of sulfonylurea receptor 1 in progressive secondary hemorrhage after brain contusion. J Neurotrauma 26:2257-2267
    • (2009) J Neurotrauma , vol.26 , pp. 2257-2267
    • Simard, J.M.1    Kilbourne, M.2    Tsymbalyuk, O.3
  • 34
    • 0343247794 scopus 로고    scopus 로고
    • The biphasic opening of the blood-brain barrier in the cortex and hippocampus after traumatic brain injury in rats
    • Başkaya MK, Rao AM, Doğan A et al (1997) The biphasic opening of the blood-brain barrier in the cortex and hippocampus after traumatic brain injury in rats. Neurosci Lett 226:33-36
    • (1997) Neurosci Lett , vol.226 , pp. 33-36
    • Başkaya, M.K.1    Rao, A.M.2    Doğan, A.3
  • 35
    • 35848967588 scopus 로고    scopus 로고
    • Neuroinflammatory responses after experimental diffuse traumatic brain injury
    • Kelley BJ, Lifshitz J, Povlishock JT (2007) Neuroinflammatory responses after experimental diffuse traumatic brain injury. J Neuropathol Exp Neurol 66:989-1001
    • (2007) J Neuropathol Exp Neurol , vol.66 , pp. 989-1001
    • Kelley, B.J.1    Lifshitz, J.2    Povlishock, J.T.3
  • 36
    • 0030971953 scopus 로고    scopus 로고
    • Ultrastructural study of brain microvessels in patients with traumatic cerebral contusions
    • Vaz R, Sarmento A, Borges N et al (1997) Ultrastructural study of brain microvessels in patients with traumatic cerebral contusions. Acta Neurochir (Wien) 139:215-220
    • (1997) Acta Neurochir (Wien) , vol.139 , pp. 215-220
    • Vaz, R.1    Sarmento, A.2    Borges, N.3
  • 37
    • 0035186465 scopus 로고    scopus 로고
    • Characteristics of sustained blood-brain barrier opening and tissue injury in a model for focal trauma in the rat
    • Preston E, Webster J, Small D (2001) Characteristics of sustained blood-brain barrier opening and tissue injury in a model for focal trauma in the rat. J Neurotrauma 18:83-92
    • (2001) J Neurotrauma , vol.18 , pp. 83-92
    • Preston, E.1    Webster, J.2    Small, D.3
  • 39
    • 0141705210 scopus 로고    scopus 로고
    • Blood-spinal cord barrier after spinal cord injury: relation to revascularization and wound healing
    • Whetstone WD, Hsu JY, Eisenberg M et al (2003) Blood-spinal cord barrier after spinal cord injury: relation to revascularization and wound healing. J Neurosci Res 74:227-239
    • (2003) J Neurosci Res , vol.74 , pp. 227-239
    • Whetstone, W.D.1    Hsu, J.Y.2    Eisenberg, M.3
  • 40
    • 0030560684 scopus 로고    scopus 로고
    • A quantitative spatial analysis of the bloodspinal cord barrier. I. Permeability changes after experimental spinal contusion injury
    • Popovich PG, Horner PJ, Mullin BB et al (1996) A quantitative spatial analysis of the bloodspinal cord barrier. I. Permeability changes after experimental spinal contusion injury. Exp Neurol 142:258-275
    • (1996) Exp Neurol , vol.142 , pp. 258-275
    • Popovich, P.G.1    Horner, P.J.2    Mullin, B.B.3
  • 41
    • 33749520483 scopus 로고    scopus 로고
    • Combination of thrombin and matrix metalloproteinase-9 exacerbates neurotoxicity in cell culture and intracerebral hemorrhage in mice
    • Xue M, Hollenberg MD, Yong VW (2006) Combination of thrombin and matrix metalloproteinase-9 exacerbates neurotoxicity in cell culture and intracerebral hemorrhage in mice. J Neurosci 26:10281-10291
    • (2006) J Neurosci , vol.26 , pp. 10281-10291
    • Xue, M.1    Hollenberg, M.D.2    Yong, V.W.3
  • 42
    • 34047151833 scopus 로고    scopus 로고
    • Cyclin D1, cdk4, and Bim are involved in thrombin-induced apoptosis in cultured cortical neurons
    • Rao HV, Thirumangalakudi L, Desmond P et al (2007) Cyclin D1, cdk4, and Bim are involved in thrombin-induced apoptosis in cultured cortical neurons. J Neurochem 101:498-505
    • (2007) J Neurochem , vol.101 , pp. 498-505
    • Rao, H.V.1    Thirumangalakudi, L.2    Desmond, P.3
  • 43
    • 34547791784 scopus 로고    scopus 로고
    • Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease
    • Paul J, Strickland S, Melchor JP (2007) Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease. J Exp Med 204:1999-2008
    • (2007) J Exp Med , vol.204 , pp. 1999-2008
    • Paul, J.1    Strickland, S.2    Melchor, J.P.3
  • 44
    • 33646470272 scopus 로고    scopus 로고
    • Predominance of cellular edema in traumatic brain swelling in patients with severe head injuries
    • Marmarou A, Signoretti S, Fatouros PP et al (2006) Predominance of cellular edema in traumatic brain swelling in patients with severe head injuries. J Neurosurg 104:720-730
    • (2006) J Neurosurg , vol.104 , pp. 720-730
    • Marmarou, A.1    Signoretti, S.2    Fatouros, P.P.3
  • 45
    • 79951677674 scopus 로고    scopus 로고
    • Prediction of neurological recovery using apparent diffusion coefficient in cases of incomplete spinal cord injury
    • Endo T, Suzuki S, Utsunomiya A et al (2011) Prediction of neurological recovery using apparent diffusion coefficient in cases of incomplete spinal cord injury. Neurosurgery 68:329-336
    • (2011) Neurosurgery , vol.68 , pp. 329-336
    • Endo, T.1    Suzuki, S.2    Utsunomiya, A.3
  • 46
    • 0033944791 scopus 로고    scopus 로고
    • Pericyte migration from the vascular wall in response to traumatic brain injury
    • Dore-Duffy P, Owen C, Balabanov R et al (2000) Pericyte migration from the vascular wall in response to traumatic brain injury. Microvasc Res 60:55-69
    • (2000) Microvasc Res , vol.60 , pp. 55-69
    • Dore-Duffy, P.1    Owen, C.2    Balabanov, R.3
  • 47
    • 20344373695 scopus 로고    scopus 로고
    • Multiple roles for MMPs and TIMPs in cerebral ischemia
    • Cunningham LA, Wetzel M, Rosenberg GA (2005) Multiple roles for MMPs and TIMPs in cerebral ischemia. Glia 50:329-339
    • (2005) Glia , vol.50 , pp. 329-339
    • Cunningham, L.A.1    Wetzel, M.2    Rosenberg, G.A.3
  • 48
    • 33947493391 scopus 로고    scopus 로고
    • Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat
    • Yang Y, Estrada EY, Thompson JF et al (2007) Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat. J Cereb Blood Flow Metab 27:697-709
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 697-709
    • Yang, Y.1    Estrada, E.Y.2    Thompson, J.F.3
  • 49
    • 34547793659 scopus 로고    scopus 로고
    • Vasogenic edema due to tight junction disruption by matrix metalloproteinases in cerebral ischemia
    • Rosenberg GA, Yang Y (2007) Vasogenic edema due to tight junction disruption by matrix metalloproteinases in cerebral ischemia. Neurosurg Focus 22:E4
    • (2007) Neurosurg Focus , vol.22 , pp. E4
    • Rosenberg, G.A.1    Yang, Y.2
  • 50
    • 0035793934 scopus 로고    scopus 로고
    • Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures
    • Rosenberg GA, Cunningham LA, Wallace J et al (2001) Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures. Brain Res 893:104-112
    • (2001) Brain Res , vol.893 , pp. 104-112
    • Rosenberg, G.A.1    Cunningham, L.A.2    Wallace, J.3
  • 51
    • 0036758650 scopus 로고    scopus 로고
    • Matrix metalloproteinases limit functional recovery after spinal cord injury by modulation of early vascular events
    • Noble LJ, Donovan F, Igarashi T et al (2002) Matrix metalloproteinases limit functional recovery after spinal cord injury by modulation of early vascular events. J Neurosci 22:7526-7535
    • (2002) J Neurosci , vol.22 , pp. 7526-7535
    • Noble, L.J.1    Donovan, F.2    Igarashi, T.3
  • 52
    • 0242442568 scopus 로고    scopus 로고
    • An adverse role for matrix metalloproteinase 12 after spinal cord injury in mice
    • Wells JE, Rice TK, Nuttall RK et al (2003) An adverse role for matrix metalloproteinase 12 after spinal cord injury in mice. J Neurosci 23:10107-10115
    • (2003) J Neurosci , vol.23 , pp. 10107-10115
    • Wells, J.E.1    Rice, T.K.2    Nuttall, R.K.3
  • 53
    • 80052033836 scopus 로고    scopus 로고
    • Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro
    • Takata F, Dohgu S, Matsumoto J et al (2011) Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro. J Neuroinflammation 8:106
    • (2011) J Neuroinflammation , vol.8 , pp. 106
    • Takata, F.1    Dohgu, S.2    Matsumoto, J.3
  • 54
    • 33845665284 scopus 로고    scopus 로고
    • Diapedesis of monocytes is associated with MMP-mediated occludin disappearance in brain endothelial cells
    • Reijerkerk A, Kooij G, van der Pol SM et al (2006) Diapedesis of monocytes is associated with MMP-mediated occludin disappearance in brain endothelial cells. FASEB J 20:2550-2552
    • (2006) FASEB J , vol.20 , pp. 2550-2552
    • Reijerkerk, A.1    Kooij, G.2    van der Pol, S.M.3
  • 55
    • 27544505259 scopus 로고    scopus 로고
    • Influence of therapeutic hypothermia on matrix metalloproteinase activity after traumatic brain injury in rats
    • Truettner JS, Alonso OF, Dalton Dietrich W (2005) Influence of therapeutic hypothermia on matrix metalloproteinase activity after traumatic brain injury in rats. J Cereb Blood Flow Metab 25:1505-1516
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 1505-1516
    • Truettner, J.S.1    Alonso, O.F.2    Dalton Dietrich, W.3
  • 56
    • 0141497935 scopus 로고    scopus 로고
    • Differential temporal expression of matrix metalloproteinases after spinal cord injury: relationship to revascularization and wound healing
    • Goussev S, Hsu JY, Lin Y et al (2003) Differential temporal expression of matrix metalloproteinases after spinal cord injury: relationship to revascularization and wound healing. J Neurosurg 99:188-197
    • (2003) J Neurosurg , vol.99 , pp. 188-197
    • Goussev, S.1    Hsu, J.Y.2    Lin, Y.3
  • 57
    • 0034666112 scopus 로고    scopus 로고
    • Effects of matrix metalloproteinase-9 gene knock-out on morphological and motor outcomes after traumatic brain injury
    • Wang X, Jung J, Asahi M et al (2000) Effects of matrix metalloproteinase-9 gene knock-out on morphological and motor outcomes after traumatic brain injury. J Neurosci 20:7037-7042
    • (2000) J Neurosci , vol.20 , pp. 7037-7042
    • Wang, X.1    Jung, J.2    Asahi, M.3
  • 58
    • 0033638508 scopus 로고    scopus 로고
    • Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94
    • Asahi M, Asahi K, Jung JC et al (2000) Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94. J Cereb Blood Flow Metab 20:1681-1689
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 1681-1689
    • Asahi, M.1    Asahi, K.2    Jung, J.C.3
  • 59
    • 33749174156 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 facilitates wound healing events that promote functional recovery after spinal cord injury
    • Hsu JY, McKeon R, Goussev S et al (2006) Matrix metalloproteinase-2 facilitates wound healing events that promote functional recovery after spinal cord injury. J Neurosci 26:9841-9850
    • (2006) J Neurosci , vol.26 , pp. 9841-9850
    • Hsu, J.Y.1    McKeon, R.2    Goussev, S.3
  • 60
    • 33645744014 scopus 로고    scopus 로고
    • Role of matrix metalloproteinases in delayed cortical responses after stroke
    • Zhao BQ, Wang S, Kim HY et al (2006) Role of matrix metalloproteinases in delayed cortical responses after stroke. Nat Med 12:441-445
    • (2006) Nat Med , vol.12 , pp. 441-445
    • Zhao, B.Q.1    Wang, S.2    Kim, H.Y.3
  • 61
    • 33646171693 scopus 로고    scopus 로고
    • Recovery at one year following isolated traumatic brain injury: a Western Trauma Association prospective multicenter trial
    • discussion 1304
    • Livingston DH, Lavery RF, Mosenthal AC et al (2005) Recovery at one year following isolated traumatic brain injury: a Western Trauma Association prospective multicenter trial. J Trauma 59:1298-1304, discussion 1304
    • (2005) J Trauma , vol.59 , pp. 1298-1304
    • Livingston, D.H.1    Lavery, R.F.2    Mosenthal, A.C.3
  • 62
    • 33646465130 scopus 로고    scopus 로고
    • Outcome after traumatic brain injury sustained in older adulthood: a one-year longitudinal study
    • Rapoport MJ, Herrmann N, Shammi P et al (2006) Outcome after traumatic brain injury sustained in older adulthood: a one-year longitudinal study. Am J Geriatr Psychiatry 14:456-465
    • (2006) Am J Geriatr Psychiatry , vol.14 , pp. 456-465
    • Rapoport, M.J.1    Herrmann, N.2    Shammi, P.3
  • 63
    • 0025838330 scopus 로고
    • The effect of age on outcome following traumatic brain injury in rats
    • Hamm RJ, Jenkins LW, Lyeth BG et al (1991) The effect of age on outcome following traumatic brain injury in rats. J Neurosurg 75:916-921
    • (1991) J Neurosurg , vol.75 , pp. 916-921
    • Hamm, R.J.1    Jenkins, L.W.2    Lyeth, B.G.3
  • 64
    • 39149109142 scopus 로고    scopus 로고
    • Detrimental effects of aging on outcome from traumatic brain injury: a behavioral, magnetic resonance imaging, and histological study in mice
    • Onyszchuk G, He YY, Berman NE et al (2008) Detrimental effects of aging on outcome from traumatic brain injury: a behavioral, magnetic resonance imaging, and histological study in mice. J Neurotrauma 25:153-171
    • (2008) J Neurotrauma , vol.25 , pp. 153-171
    • Onyszchuk, G.1    He, Y.Y.2    Berman, N.E.3
  • 65
    • 84873452455 scopus 로고    scopus 로고
    • Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states
    • Kumar A, Stoica BA, Sabirzhanov B et al (2013) Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states. Neurobiol Aging 34:1397-1411
    • (2013) Neurobiol Aging , vol.34 , pp. 1397-1411
    • Kumar, A.1    Stoica, B.A.2    Sabirzhanov, B.3
  • 66
    • 84862793270 scopus 로고    scopus 로고
    • Effects of aging on blood brain barrier and matrix metalloproteases following controlled cortical impact in mice
    • Lee P, Kim J, Williams R et al (2012) Effects of aging on blood brain barrier and matrix metalloproteases following controlled cortical impact in mice. Exp Neurol 234:50-61
    • (2012) Exp Neurol , vol.234 , pp. 50-61
    • Lee, P.1    Kim, J.2    Williams, R.3
  • 67
    • 42349095894 scopus 로고    scopus 로고
    • Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke
    • Kidwell CS, Latour L, Saver JL et al (2008) Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke. Cerebrovasc Dis 25:338-343
    • (2008) Cerebrovasc Dis , vol.25 , pp. 338-343
    • Kidwell, C.S.1    Latour, L.2    Saver, J.L.3
  • 68
    • 58249118833 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic
    • Yepes M, Roussel BD, Ali C et al (2009) Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic. Trends Neurosci 32:48-55
    • (2009) Trends Neurosci , vol.32 , pp. 48-55
    • Yepes, M.1    Roussel, B.D.2    Ali, C.3
  • 69
    • 33746080943 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator: a multifaceted modulator of neurotransmission and synaptic plasticity
    • Samson AL, Medcalf RL (2006) Tissue-type plasminogen activator: a multifaceted modulator of neurotransmission and synaptic plasticity. Neuron 50:673-678
    • (2006) Neuron , vol.50 , pp. 673-678
    • Samson, A.L.1    Medcalf, R.L.2
  • 70
    • 20944452152 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis
    • Benchenane K, Berezowski V, Ali C et al (2005) Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis. Circulation 111:2241-2249
    • (2005) Circulation , vol.111 , pp. 2241-2249
    • Benchenane, K.1    Berezowski, V.2    Ali, C.3
  • 71
    • 0028850375 scopus 로고
    • Expression of tissue plasminogen activator in cerebral capillaries: possible fibrinolytic function of the blood-brain barrier
    • Zlokovic BV, Wang L, Sun N et al (1995) Expression of tissue plasminogen activator in cerebral capillaries: possible fibrinolytic function of the blood-brain barrier. Neurosurgery 37:955-961
    • (1995) Neurosurgery , vol.37 , pp. 955-961
    • Zlokovic, B.V.1    Wang, L.2    Sun, N.3
  • 72
    • 31444447324 scopus 로고    scopus 로고
    • Brain endothelial hemostasis regulation by pericytes
    • Kim JA, Tran ND, Li Z et al (2006) Brain endothelial hemostasis regulation by pericytes. J Cereb Blood Flow Metab 26:209-217
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 209-217
    • Kim, J.A.1    Tran, N.D.2    Li, Z.3
  • 73
    • 0031775308 scopus 로고    scopus 로고
    • Astrocyte regulation of endothelial tissue plasminogen activator in a blood-brain barrier model
    • Tran ND, Schreiber SS, Fisher M (1998) Astrocyte regulation of endothelial tissue plasminogen activator in a blood-brain barrier model. J Cereb Blood Flow Metab 18:1316-1324
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 1316-1324
    • Tran, N.D.1    Schreiber, S.S.2    Fisher, M.3
  • 74
    • 0029163303 scopus 로고
    • Components of the plasminogen activator system in astrocytes are modulated by tumor necrosis factor-alpha and interleukin-1 beta through similar signal transduction pathways
    • Faber-Elman A, Miskin R, Schwartz M (1995) Components of the plasminogen activator system in astrocytes are modulated by tumor necrosis factor-alpha and interleukin-1 beta through similar signal transduction pathways. J Neurochem 65:1524-1535
    • (1995) J Neurochem , vol.65 , pp. 1524-1535
    • Faber-Elman, A.1    Miskin, R.2    Schwartz, M.3
  • 75
    • 84859534535 scopus 로고    scopus 로고
    • Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals
    • Cassé F, Bardou I, Danglot L et al (2012) Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals. J Neurosci 32:5186-5199
    • (2012) J Neurosci , vol.32 , pp. 5186-5199
    • Cassé, F.1    Bardou, I.2    Danglot, L.3
  • 76
    • 0031021357 scopus 로고    scopus 로고
    • An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus
    • Tsirka SE, Rogove AD, Bugge TH et al (1997) An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus. J Neurosci 17:543-552
    • (1997) J Neurosci , vol.17 , pp. 543-552
    • Tsirka, S.E.1    Rogove, A.D.2    Bugge, T.H.3
  • 77
    • 0345824713 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein
    • Yepes M, Sandkvist M, Moore EG et al (2003) Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein. J Clin Invest 112:1533-1540
    • (2003) J Clin Invest , vol.112 , pp. 1533-1540
    • Yepes, M.1    Sandkvist, M.2    Moore, E.G.3
  • 78
    • 46749118298 scopus 로고    scopus 로고
    • Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke
    • Su EJ, Fredriksson L, Geyer M et al (2008) Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke. Nat Med 14:731-737
    • (2008) Nat Med , vol.14 , pp. 731-737
    • Su, E.J.1    Fredriksson, L.2    Geyer, M.3
  • 79
    • 34147143557 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit
    • Polavarapu R, Gongora MC, Yi H et al (2007) Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit. Blood 109:3270-3278
    • (2007) Blood , vol.109 , pp. 3270-3278
    • Polavarapu, R.1    Gongora, M.C.2    Yi, H.3
  • 80
    • 84870155536 scopus 로고    scopus 로고
    • The tissue-type plasminogen activatorplasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma:evidence from mice and humans
    • Sashindranath M, Sales E, Daglas M et al (2012) The tissue-type plasminogen activatorplasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma:evidence from mice and humans. Brain 135:3251-3264
    • (2012) Brain , vol.135 , pp. 3251-3264
    • Sashindranath, M.1    Sales, E.2    Daglas, M.3
  • 81
    • 34047230161 scopus 로고    scopus 로고
    • Induction of matrix metalloproteinase, cytokines and chemokines in rat cortical astrocytes exposed to plasminogen activators
    • Lee SR, Guo SZ, Scannevin RH et al (2007) Induction of matrix metalloproteinase, cytokines and chemokines in rat cortical astrocytes exposed to plasminogen activators. Neurosci Lett 417:1-5
    • (2007) Neurosci Lett , vol.417 , pp. 1-5
    • Lee, S.R.1    Guo, S.Z.2    Scannevin, R.H.3
  • 82
    • 0142137232 scopus 로고    scopus 로고
    • Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator
    • Wang X, Lee SR, Arai K et al (2003) Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator. Nat Med 9:1313-1317
    • (2003) Nat Med , vol.9 , pp. 1313-1317
    • Wang, X.1    Lee, S.R.2    Arai, K.3
  • 83
    • 70350462242 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein
    • Suzuki Y, Nagai N, Yamakawa K et al (2009) Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein. Blood 114:3352-3358
    • (2009) Blood , vol.114 , pp. 3352-3358
    • Suzuki, Y.1    Nagai, N.2    Yamakawa, K.3
  • 84
    • 33644869414 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression
    • Hu K, Yang J, Tanaka S et al (2006) Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression. J Biol Chem 281:2120-2127
    • (2006) J Biol Chem , vol.281 , pp. 2120-2127
    • Hu, K.1    Yang, J.2    Tanaka, S.3
  • 85
    • 6344236867 scopus 로고    scopus 로고
    • Tissue plasminogen activator is a potent activator of PDGF-CC
    • Fredriksson L, Li H, Fieber C et al (2004) Tissue plasminogen activator is a potent activator of PDGF-CC. EMBO J 23:3793-3802
    • (2004) EMBO J , vol.23 , pp. 3793-3802
    • Fredriksson, L.1    Li, H.2    Fieber, C.3
  • 86
    • 0033776193 scopus 로고    scopus 로고
    • PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor
    • Li X, Ponten A, Aase K et al (2000) PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor. Nat Cell Biol 2:302-309
    • (2000) Nat Cell Biol , vol.2 , pp. 302-309
    • Li, X.1    Ponten, A.2    Aase, K.3
  • 87
    • 0036585026 scopus 로고    scopus 로고
    • Tissue plasminogen activator mediates microglial activation via its finger domain through annexin II
    • Siao CJ, Tsirka SE (2002) Tissue plasminogen activator mediates microglial activation via its finger domain through annexin II. J Neurosci 22:3352-3358
    • (2002) J Neurosci , vol.22 , pp. 3352-3358
    • Siao, C.J.1    Tsirka, S.E.2
  • 88
    • 51549107602 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrier
    • Reijerkerk A, Kooij G, van der Pol SM et al (2008) Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrier. J Immunol 181:3567-3574
    • (2008) J Immunol , vol.181 , pp. 3567-3574
    • Reijerkerk, A.1    Kooij, G.2    van der Pol, S.M.3
  • 89
    • 33847108114 scopus 로고    scopus 로고
    • Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice
    • Sheehan JJ, Zhou C, Gravanis I et al (2007) Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice. J Neurosci 27:1738-1745
    • (2007) J Neurosci , vol.27 , pp. 1738-1745
    • Sheehan, J.J.1    Zhou, C.2    Gravanis, I.3
  • 90
    • 0344465840 scopus 로고    scopus 로고
    • Potential role of MCP-1 in endothelial cell tight junction 'opening': signaling via Rho and Rho kinase
    • Stamatovic SM, Keep RF, Kunkel SL et al (2003) Potential role of MCP-1 in endothelial cell tight junction 'opening': signaling via Rho and Rho kinase. J Cell Sci 116:4615-4628
    • (2003) J Cell Sci , vol.116 , pp. 4615-4628
    • Stamatovic, S.M.1    Keep, R.F.2    Kunkel, S.L.3
  • 91
    • 79955531506 scopus 로고    scopus 로고
    • Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood-brain barrier disruption
    • Yao Y, Tsirka SE (2011) Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood-brain barrier disruption. J Cell Sci 124:1486-1495
    • (2011) J Cell Sci , vol.124 , pp. 1486-1495
    • Yao, Y.1    Tsirka, S.E.2
  • 92
    • 79959748515 scopus 로고    scopus 로고
    • Compartment- and context-specific changes in tissue-type plasminogen activator (tPA) activity following brain injury and pharmacological stimulation
    • Sashindranath M, Samson AL, Downes CE et al (2011) Compartment- and context-specific changes in tissue-type plasminogen activator (tPA) activity following brain injury and pharmacological stimulation. Lab Invest 91:1079-1091
    • (2011) Lab Invest , vol.91 , pp. 1079-1091
    • Sashindranath, M.1    Samson, A.L.2    Downes, C.E.3
  • 93
    • 80054771099 scopus 로고    scopus 로고
    • Axonal regrowth after spinal cord injury via chondroitinase and the tissue plasminogen activator (tPA)/plasmin system
    • Bukhari N, Torres L, Robinson JK et al (2011) Axonal regrowth after spinal cord injury via chondroitinase and the tissue plasminogen activator (tPA)/plasmin system. J Neurosci 31:14931-14943
    • (2011) J Neurosci , vol.31 , pp. 14931-14943
    • Bukhari, N.1    Torres, L.2    Robinson, J.K.3
  • 94
    • 0037263651 scopus 로고    scopus 로고
    • Decreased neural damage after spinal cord injury in tPA-deficient mice
    • Abe Y, Nakamura H, Yoshino O et al (2003) Decreased neural damage after spinal cord injury in tPA-deficient mice. J Neurotrauma 20:43-57
    • (2003) J Neurotrauma , vol.20 , pp. 43-57
    • Abe, Y.1    Nakamura, H.2    Yoshino, O.3
  • 95
    • 0035930452 scopus 로고    scopus 로고
    • Reduced cortical injury and edema in tissue plasminogen activator knockout mice after brain trauma
    • Mori T, Wang X, Kline AE et al (2001) Reduced cortical injury and edema in tissue plasminogen activator knockout mice after brain trauma. Neuroreport 12:4117-4120
    • (2001) Neuroreport , vol.12 , pp. 4117-4120
    • Mori, T.1    Wang, X.2    Kline, A.E.3
  • 96
    • 0029796198 scopus 로고    scopus 로고
    • Apolipoprotein E gene expression in various tissues of mouse and regulation by estrogen
    • Srivastava RA, Bhasin N, Srivastava N (1996) Apolipoprotein E gene expression in various tissues of mouse and regulation by estrogen. Biochem Mol Biol Int 38:91-101
    • (1996) Biochem Mol Biol Int , vol.38 , pp. 91-101
    • Srivastava, R.A.1    Bhasin, N.2    Srivastava, N.3
  • 97
    • 27744495001 scopus 로고    scopus 로고
    • Traumatic brain injury induces biphasic upregulation of ApoE and ApoJ protein in rats
    • Iwata A, Browne KD, Chen XH et al (2005) Traumatic brain injury induces biphasic upregulation of ApoE and ApoJ protein in rats. J Neurosci Res 82:103-114
    • (2005) J Neurosci Res , vol.82 , pp. 103-114
    • Iwata, A.1    Browne, K.D.2    Chen, X.H.3
  • 98
    • 77956130453 scopus 로고    scopus 로고
    • Worldwide allele frequencies of the human apolipoprotein E gene: climate, local adaptations, and evolutionary history
    • Eisenberg DT, Kuzawa CW, Hayes MG (2010) Worldwide allele frequencies of the human apolipoprotein E gene: climate, local adaptations, and evolutionary history. Am J Phys Anthropol 143:100-111
    • (2010) Am J Phys Anthropol , vol.143 , pp. 100-111
    • Eisenberg, D.T.1    Kuzawa, C.W.2    Hayes, M.G.3
  • 99
    • 67649839967 scopus 로고    scopus 로고
    • Prediction of time trends in recovery of cognitive function after mild head injury
    • discussion 704
    • Müller K, Ingebrigtsen T, Wilsgaard T et al (2009) Prediction of time trends in recovery of cognitive function after mild head injury. Neurosurgery 64:698-704, discussion 704
    • (2009) Neurosurgery , vol.64 , pp. 698-704
    • Müller, K.1    Ingebrigtsen, T.2    Wilsgaard, T.3
  • 100
    • 0030770308 scopus 로고    scopus 로고
    • Association of apolipoprotein E polymorphism with outcome after head injury
    • Teasdale GM, Nicoll JA, MurrayGet al (1997) Association of apolipoprotein E polymorphism with outcome after head injury. Lancet 350:1069-1071
    • (1997) Lancet , vol.350 , pp. 1069-1071
    • Teasdale, G.M.1    Nicoll, J.A.2    Murray, G.3
  • 101
    • 34249106069 scopus 로고    scopus 로고
    • Apolipoprotein E4 allele presence and functional outcome after severe traumatic brain injury
    • Alexander S, Kerr ME, Kim Y et al (2007) Apolipoprotein E4 allele presence and functional outcome after severe traumatic brain injury. J Neurotrauma 24:790-797
    • (2007) J Neurotrauma , vol.24 , pp. 790-797
    • Alexander, S.1    Kerr, M.E.2    Kim, Y.3
  • 102
    • 46749151418 scopus 로고    scopus 로고
    • Apolipoprotein E ε4 allele and outcomes of traumatic spinal cord injury
    • Jha A, Lammertse DP, Coll JR et al (2008) Apolipoprotein E ε4 allele and outcomes of traumatic spinal cord injury. J Spinal Cord Med 31:171-176
    • (2008) J Spinal Cord Med , vol.31 , pp. 171-176
    • Jha, A.1    Lammertse, D.P.2    Coll, J.R.3
  • 103
    • 80052478606 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon 4 allele and outcomes of traumatic spinal cord injury in a Chinese Han population
    • Sun C, Ji G, Liu Q et al (2011) Apolipoprotein E epsilon 4 allele and outcomes of traumatic spinal cord injury in a Chinese Han population. Mol Biol Rep 38:4793-4796
    • (2011) Mol Biol Rep , vol.38 , pp. 4793-4796
    • Sun, C.1    Ji, G.2    Liu, Q.3
  • 104
    • 70450164516 scopus 로고    scopus 로고
    • Apolipoprotein E4 as a predictor of outcomes in pediatric mild traumatic brain injury
    • Moran LM, Taylor HG, Ganesalingam K et al (2009) Apolipoprotein E4 as a predictor of outcomes in pediatric mild traumatic brain injury. J Neurotrauma 26:1489-1495
    • (2009) J Neurotrauma , vol.26 , pp. 1489-1495
    • Moran, L.M.1    Taylor, H.G.2    Ganesalingam, K.3
  • 105
    • 10344256790 scopus 로고    scopus 로고
    • Six-month recovery from mild to moderate traumatic brain injury: the role of APOE-ε4 allele
    • Chamelian L, Reis M, Feinstein A (2004) Six-month recovery from mild to moderate traumatic brain injury: the role of APOE-ε4 allele. Brain 127:2621-2628
    • (2004) Brain , vol.127 , pp. 2621-2628
    • Chamelian, L.1    Reis, M.2    Feinstein, A.3
  • 106
    • 27644546646 scopus 로고    scopus 로고
    • The association between APOE ε4, age and outcome after head injury: a prospective cohort study
    • Teasdale GM, Murray GD, Nicoll JA (2005) The association between APOE ε4, age and outcome after head injury: a prospective cohort study. Brain 128:2556-2561
    • (2005) Brain , vol.128 , pp. 2556-2561
    • Teasdale, G.M.1    Murray, G.D.2    Nicoll, J.A.3
  • 107
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
    • Corder EH, Saunders AM, Strittmatter WJ et al (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261:921-923
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 108
    • 0028174629 scopus 로고
    • β amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease
    • Roberts GW, Gentleman SM, Lynch A et al (1994) β amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease. J Neurol Neurosurg Psychiatry 57:419-425
    • (1994) J Neurol Neurosurg Psychiatry , vol.57 , pp. 419-425
    • Roberts, G.W.1    Gentleman, S.M.2    Lynch, A.3
  • 109
    • 5044237263 scopus 로고    scopus 로고
    • Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury
    • Ikonomovic MD, Uryu K, Abrahamson EE et al (2004) Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury. Exp Neurol 190:192-203
    • (2004) Exp Neurol , vol.190 , pp. 192-203
    • Ikonomovic, M.D.1    Uryu, K.2    Abrahamson, E.E.3
  • 110
    • 0036896994 scopus 로고    scopus 로고
    • Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mousemodel of Alzheimer's disease
    • Hartman RE, Laurer H, Longhi L et al (2002) Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mousemodel of Alzheimer's disease. J Neurosci 22:10083-10087
    • (2002) J Neurosci , vol.22 , pp. 10083-10087
    • Hartman, R.E.1    Laurer, H.2    Longhi, L.3
  • 111
    • 0037311388 scopus 로고    scopus 로고
    • Apolipoprotein E expression after spinal cord injury in the mouse
    • Seitz A, Kragol M, Aglow E et al (2003) Apolipoprotein E expression after spinal cord injury in the mouse. J Neurosci Res 71:417-426
    • (2003) J Neurosci Res , vol.71 , pp. 417-426
    • Seitz, A.1    Kragol, M.2    Aglow, E.3
  • 112
    • 0030751161 scopus 로고    scopus 로고
    • Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury
    • Chen Y, Lomnitski L, Michaelson DM et al (1997) Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury. Neuroscience 80:1255-1262
    • (1997) Neuroscience , vol.80 , pp. 1255-1262
    • Chen, Y.1    Lomnitski, L.2    Michaelson, D.M.3
  • 113
    • 13444266299 scopus 로고    scopus 로고
    • A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury
    • Lynch JR, Wang H, Mace B et al (2005) A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury. Exp Neurol 192:109-116
    • (2005) Exp Neurol , vol.192 , pp. 109-116
    • Lynch, J.R.1    Wang, H.2    Mace, B.3
  • 114
    • 59849124156 scopus 로고    scopus 로고
    • COG1410 improves cognitive performance and reduces cortical neuronal loss in the traumatically injured brain
    • Hoane MR, Kaufman N, Vitek MP et al (2009) COG1410 improves cognitive performance and reduces cortical neuronal loss in the traumatically injured brain. J Neurotrauma 26:121-129
    • (2009) J Neurotrauma , vol.26 , pp. 121-129
    • Hoane, M.R.1    Kaufman, N.2    Vitek, M.P.3
  • 115
    • 77955275113 scopus 로고    scopus 로고
    • COG1410, an apolipoprotein E-based peptide, improves cognitive performance and reduces cortical loss following moderate fluid percussion injury in the rat
    • Kaufman NA, Beare JE, Tan AA et al (2010) COG1410, an apolipoprotein E-based peptide, improves cognitive performance and reduces cortical loss following moderate fluid percussion injury in the rat. Behav Brain Res 214:395-401
    • (2010) Behav Brain Res , vol.214 , pp. 395-401
    • Kaufman, N.A.1    Beare, J.E.2    Tan, A.A.3
  • 116
    • 0036135127 scopus 로고    scopus 로고
    • Apolipoprotein E affects the central nervous system response to injury and the development of cerebral edema
    • Lynch JR, Pineda JA, Morgan D et al (2002) Apolipoprotein E affects the central nervous system response to injury and the development of cerebral edema. Ann Neurol 51:113-117
    • (2002) Ann Neurol , vol.51 , pp. 113-117
    • Lynch, J.R.1    Pineda, J.A.2    Morgan, D.3
  • 117
    • 1542467336 scopus 로고    scopus 로고
    • APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response
    • Lynch JR, Tang W, Wang H et al (2003) APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response. J Biol Chem 278:48529-48533
    • (2003) J Biol Chem , vol.278 , pp. 48529-48533
    • Lynch, J.R.1    Tang, W.2    Wang, H.3
  • 118
    • 0035022053 scopus 로고    scopus 로고
    • Impairment of the blood-nerve and blood-brain barriers in apolipoprotein E knockout mice
    • Fullerton SM, Shirman GA, Strittmatter WJ et al (2001) Impairment of the blood-nerve and blood-brain barriers in apolipoprotein E knockout mice. Exp Neurol 169:13-22
    • (2001) Exp Neurol , vol.169 , pp. 13-22
    • Fullerton, S.M.1    Shirman, G.A.2    Strittmatter, W.J.3
  • 119
    • 34247325468 scopus 로고    scopus 로고
    • ApoE deficiency leads to a progressive age-dependent blood-brain barrier leakage
    • Hafezi-Moghadam A, Thomas KL, Wagner DD (2007) ApoE deficiency leads to a progressive age-dependent blood-brain barrier leakage. Am J Physiol Cell Physiol 292:C1256-C1262
    • (2007) Am J Physiol Cell Physiol , vol.292 , pp. C1256-C1262
    • Hafezi-Moghadam, A.1    Thomas, K.L.2    Wagner, D.D.3
  • 120
    • 79955953909 scopus 로고    scopus 로고
    • Apolipoprotein E regulates the integrity of tight junctions in an isoform-dependent manner in an in vitro blood-brain barrier model
    • Nishitsuji K, Hosono T, Nakamura T et al (2011) Apolipoprotein E regulates the integrity of tight junctions in an isoform-dependent manner in an in vitro blood-brain barrier model. J Biol Chem 286:17536-17542
    • (2011) J Biol Chem , vol.286 , pp. 17536-17542
    • Nishitsuji, K.1    Hosono, T.2    Nakamura, T.3
  • 121
    • 58549096092 scopus 로고    scopus 로고
    • PKCη regulates occludin phosphorylation and epithelial tight junction integrity
    • Suzuki T, Elias BC, Seth A et al (2009) PKCη regulates occludin phosphorylation and epithelial tight junction integrity. Proc Natl Acad Sci U S A 106:61-66
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 61-66
    • Suzuki, T.1    Elias, B.C.2    Seth, A.3
  • 122
    • 84861418194 scopus 로고    scopus 로고
    • Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
    • Bell RD, Winkler EA, Singh I et al (2012) Apolipoprotein E controls cerebrovascular integrity via cyclophilin A. Nature 485:512-516
    • (2012) Nature , vol.485 , pp. 512-516
    • Bell, R.D.1    Winkler, E.A.2    Singh, I.3
  • 123
    • 0021159379 scopus 로고
    • Cyclophilin: a specific cytosolic binding protein for cyclosporin A
    • Handschumacher RE, Harding MW, Rice J et al (1984) Cyclophilin: a specific cytosolic binding protein for cyclosporin A. Science 226:544-547
    • (1984) Science , vol.226 , pp. 544-547
    • Handschumacher, R.E.1    Harding, M.W.2    Rice, J.3
  • 124
    • 3042730974 scopus 로고    scopus 로고
    • Cyclophilin A is a proinflammatory cytokine that activates endothelial cells
    • Jin ZG, Lungu AO, Xie L et al (2004) Cyclophilin A is a proinflammatory cytokine that activates endothelial cells. Arterioscler Thromb Vasc Biol 24:1186-1191
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1186-1191
    • Jin, Z.G.1    Lungu, A.O.2    Xie, L.3
  • 125
    • 79959487580 scopus 로고    scopus 로고
    • Cyclophilin A cooperates with MIP-2 to augment neutrophil migration
    • Heine SJ, Olive D, Gao JL et al (2011) Cyclophilin A cooperates with MIP-2 to augment neutrophil migration. J Inflamm Res 4:93-104
    • (2011) J Inflamm Res , vol.4 , pp. 93-104
    • Heine, S.J.1    Olive, D.2    Gao, J.L.3
  • 126
    • 66249147220 scopus 로고    scopus 로고
    • Endogenous signals initiating inflammation in the injured nervous system
    • Pineau I, Lacroix S (2009) Endogenous signals initiating inflammation in the injured nervous system. Glia 57:351-361
    • (2009) Glia , vol.57 , pp. 351-361
    • Pineau, I.1    Lacroix, S.2
  • 127
    • 84864621433 scopus 로고    scopus 로고
    • Cerebrospinal fluid levels of high-mobility group box 1 and cytochrome C predict outcome after pediatric traumatic brain injury
    • Au AK, Aneja RK, Bell MJ et al (2012) Cerebrospinal fluid levels of high-mobility group box 1 and cytochrome C predict outcome after pediatric traumatic brain injury. J Neurotrauma 29:2013-2021
    • (2012) J Neurotrauma , vol.29 , pp. 2013-2021
    • Au, A.K.1    Aneja, R.K.2    Bell, M.J.3
  • 128
    • 0033538467 scopus 로고    scopus 로고
    • HMG-1 as a late mediator of endotoxin lethality in mice
    • Wang H, Bloom O, Zhang M et al (1999) HMG-1 as a late mediator of endotoxin lethality in mice. Science 285:248-251
    • (1999) Science , vol.285 , pp. 248-251
    • Wang, H.1    Bloom, O.2    Zhang, M.3
  • 129
    • 77956225959 scopus 로고    scopus 로고
    • Expression and regulation of toll-like receptors in cerebral endothelial cells
    • Nagyoszi P, Wilhelm I, Farkas AE et al (2010) Expression and regulation of toll-like receptors in cerebral endothelial cells. Neurochem Int 57:556-564
    • (2010) Neurochem Int , vol.57 , pp. 556-564
    • Nagyoszi, P.1    Wilhelm, I.2    Farkas, A.E.3
  • 130
    • 33847099936 scopus 로고    scopus 로고
    • Astrocytes are active players in cerebral innate immunity
    • Farina C, Aloisi F, Meinl E (2007) Astrocytes are active players in cerebral innate immunity. Trends Immunol 28:138-145
    • (2007) Trends Immunol , vol.28 , pp. 138-145
    • Farina, C.1    Aloisi, F.2    Meinl, E.3
  • 131
    • 77952095680 scopus 로고    scopus 로고
    • Lipopolysaccharide-activated microglia induce dysfunction of the blood-brain barrier in rat microvascular endothelial cells co-cultured with microglia
    • Sumi N, Nishioku T, Takata F et al (2010) Lipopolysaccharide-activated microglia induce dysfunction of the blood-brain barrier in rat microvascular endothelial cells co-cultured with microglia. Cell Mol Neurobiol 30:247-253
    • (2010) Cell Mol Neurobiol , vol.30 , pp. 247-253
    • Sumi, N.1    Nishioku, T.2    Takata, F.3
  • 132
    • 45049087782 scopus 로고    scopus 로고
    • TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration
    • Kilic U, Kilic E, Matter CM et al (2008) TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration. Neurobiol Dis 31:33-40
    • (2008) Neurobiol Dis , vol.31 , pp. 33-40
    • Kilic, U.1    Kilic, E.2    Matter, C.M.3
  • 133
    • 77957858212 scopus 로고    scopus 로고
    • Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia
    • Hyakkoku K, Hamanaka J, Tsuruma K et al (2010) Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia. Neuroscience 171:258-267
    • (2010) Neuroscience , vol.171 , pp. 258-267
    • Hyakkoku, K.1    Hamanaka, J.2    Tsuruma, K.3
  • 134
    • 34247545017 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke
    • Caso JR, Pradillo JM, Hurtado O et al (2007) Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke. Circulation 115:1599-1608
    • (2007) Circulation , vol.115 , pp. 1599-1608
    • Caso, J.R.1    Pradillo, J.M.2    Hurtado, O.3
  • 135
    • 84857777838 scopus 로고    scopus 로고
    • Genetic ablation of toll-like receptor 2 reduces secondary brain injury caused by cortical contusion in mice
    • Yu ZQ, Zha JH (2012) Genetic ablation of toll-like receptor 2 reduces secondary brain injury caused by cortical contusion in mice. Ann Clin Lab Sci 42:26-33
    • (2012) Ann Clin Lab Sci , vol.42 , pp. 26-33
    • Yu, Z.Q.1    Zha, J.H.2
  • 136
    • 34250160228 scopus 로고    scopus 로고
    • TLR2 has a detrimental role in mouse transient focal cerebral ischemia
    • Ziegler G, Harhausen D, Schepers C et al (2007) TLR2 has a detrimental role in mouse transient focal cerebral ischemia. Biochem Biophys Res Commun 359:574-579
    • (2007) Biochem Biophys Res Commun , vol.359 , pp. 574-579
    • Ziegler, G.1    Harhausen, D.2    Schepers, C.3
  • 137
    • 34250182782 scopus 로고    scopus 로고
    • Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury
    • Kigerl KA, Lai W, Rivest S et al (2007) Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury. J Neurochem 102:37-50
    • (2007) J Neurochem , vol.102 , pp. 37-50
    • Kigerl, K.A.1    Lai, W.2    Rivest, S.3
  • 138
    • 84856728400 scopus 로고    scopus 로고
    • Expression of inflammatory cytokines following acute spinal cord injury in a rodent model
    • Stammers AT, Liu J, Kwon BK (2012) Expression of inflammatory cytokines following acute spinal cord injury in a rodent model. J Neurosci Res 90:782-790
    • (2012) J Neurosci Res , vol.90 , pp. 782-790
    • Stammers, A.T.1    Liu, J.2    Kwon, B.K.3
  • 139
    • 0029620361 scopus 로고
    • Inflammatory leukocytic recruitment and diffuse neuronal degeneration are separate pathological processes resulting from traumatic brain injury
    • Soares HD, Hicks RR, Smith D et al (1995) Inflammatory leukocytic recruitment and diffuse neuronal degeneration are separate pathological processes resulting from traumatic brain injury. J Neurosci 15:8223-8233
    • (1995) J Neurosci , vol.15 , pp. 8223-8233
    • Soares, H.D.1    Hicks, R.R.2    Smith, D.3
  • 140
    • 0033606040 scopus 로고    scopus 로고
    • Kinetics of polymorphonuclear neutrophil infiltration after a traumatic brain injury in rat
    • Royo NC,Wahl F, Stutzmann JM (1999) Kinetics of polymorphonuclear neutrophil infiltration after a traumatic brain injury in rat. Neuroreport 10:1363-1367
    • (1999) Neuroreport , vol.10 , pp. 1363-1367
    • Royo, N.C.1    Wahl, F.2    Stutzmann, J.M.3
  • 141
    • 77249125330 scopus 로고    scopus 로고
    • Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment
    • Beck KD, Nguyen HX, Galvan MD et al (2010) Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment. Brain 133:433-447
    • (2010) Brain , vol.133 , pp. 433-447
    • Beck, K.D.1    Nguyen, H.X.2    Galvan, M.D.3
  • 142
    • 77955893200 scopus 로고    scopus 로고
    • Vasopressin amplifies the production of proinflammatory mediators in traumatic brain injury
    • Szmydynger-Chodobska J, Fox LM, Lynch KM et al (2010) Vasopressin amplifies the production of proinflammatory mediators in traumatic brain injury. J Neurotrauma 27:1449-1461
    • (2010) J Neurotrauma , vol.27 , pp. 1449-1461
    • Szmydynger-Chodobska, J.1    Fox, L.M.2    Lynch, K.M.3
  • 143
    • 79953091772 scopus 로고    scopus 로고
    • Deficiency of the chemokine receptor CXCR2 attenuates neutrophil infiltration and cortical damage following closed head injury
    • Semple BD, Bye N, Ziebell JM et al (2010) Deficiency of the chemokine receptor CXCR2 attenuates neutrophil infiltration and cortical damage following closed head injury. Neurobiol Dis 40:394-403
    • (2010) Neurobiol Dis , vol.40 , pp. 394-403
    • Semple, B.D.1    Bye, N.2    Ziebell, J.M.3
  • 144
    • 84856031624 scopus 로고    scopus 로고
    • Neutrophil depletion reduces edema formation and tissue loss following traumatic brain injury in mice
    • Kenne E, Erlandsson A, Lindbom L et al (2012) Neutrophil depletion reduces edema formation and tissue loss following traumatic brain injury in mice. J Neuroinflammation 9:17
    • (2012) J Neuroinflammation , vol.9 , pp. 17
    • Kenne, E.1    Erlandsson, A.2    Lindbom, L.3
  • 145
    • 77950520442 scopus 로고    scopus 로고
    • Role of CCL2 (MCP-1) in traumatic brain injury (TBI): evidence from severe TBI patients and CCL2_/_ mice
    • Semple BD, Bye N, Rancan M et al (2010) Role of CCL2 (MCP-1) in traumatic brain injury (TBI): evidence from severe TBI patients and CCL2_/_ mice. J Cereb Blood Flow Metab 30:769-782
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 769-782
    • Semple, B.D.1    Bye, N.2    Rancan, M.3
  • 146
    • 41949101390 scopus 로고    scopus 로고
    • Transient blockage of the CD11d/CD18 integrin reduces contusion volume and macrophage infiltration after traumatic brain injury in rats
    • Utagawa A, Bramlett HM, Daniels L et al (2008) Transient blockage of the CD11d/CD18 integrin reduces contusion volume and macrophage infiltration after traumatic brain injury in rats. Brain Res 1207:155-163
    • (2008) Brain Res , vol.1207 , pp. 155-163
    • Utagawa, A.1    Bramlett, H.M.2    Daniels, L.3
  • 147
    • 84867011503 scopus 로고    scopus 로고
    • A CD11d monoclonal antibody treatment reduces tissue injury and improves neurological outcome after fluid percussion brain injury in rats
    • Bao F, Shultz SR, Hepburn JD et al (2012) A CD11d monoclonal antibody treatment reduces tissue injury and improves neurological outcome after fluid percussion brain injury in rats. J Neurotrauma 29:2375-2392
    • (2012) J Neurotrauma , vol.29 , pp. 2375-2392
    • Bao, F.1    Shultz, S.R.2    Hepburn, J.D.3
  • 148
    • 0032838089 scopus 로고    scopus 로고
    • Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury
    • Popovich PG, Guan Z, Wei P et al (1999) Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. Exp Neurol 158:351-365
    • (1999) Exp Neurol , vol.158 , pp. 351-365
    • Popovich, P.G.1    Guan, Z.2    Wei, P.3
  • 149
    • 80054807341 scopus 로고    scopus 로고
    • Prevention of both neutrophil and monocyte recruitment promotes recovery after spinal cord injury
    • Lee SM, Rosen S, Weinstein P et al (2011) Prevention of both neutrophil and monocyte recruitment promotes recovery after spinal cord injury. J Neurotrauma 28:1893-1907
    • (2011) J Neurotrauma , vol.28 , pp. 1893-1907
    • Lee, S.M.1    Rosen, S.2    Weinstein, P.3
  • 150
    • 2142821430 scopus 로고    scopus 로고
    • Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function
    • Gris D, Marsh DR, Oatway MA et al (2004) Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function. J Neurosci 24:4043-4051
    • (2004) J Neurosci , vol.24 , pp. 4043-4051
    • Gris, D.1    Marsh, D.R.2    Oatway, M.A.3
  • 151
    • 84857340458 scopus 로고    scopus 로고
    • CD11d antibody treatment improves recovery in spinal cord-injured mice
    • Geremia NM, Bao F, Rosenzweig TE et al (2012) CD11d antibody treatment improves recovery in spinal cord-injured mice. J Neurotrauma 29:539-550
    • (2012) J Neurotrauma , vol.29 , pp. 539-550
    • Geremia, N.M.1    Bao, F.2    Rosenzweig, T.E.3
  • 152
    • 58849083367 scopus 로고    scopus 로고
    • Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome
    • Stirling DP, Liu S, Kubes P et al (2009) Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome. J Neurosci 29:753-764
    • (2009) J Neurosci , vol.29 , pp. 753-764
    • Stirling, D.P.1    Liu, S.2    Kubes, P.3
  • 153
    • 38449102676 scopus 로고    scopus 로고
    • Macrophage activation and polarization
    • Martinez FO, Sica A, Mantovani A et al (2008) Macrophage activation and polarization. Front Biosci 13:453-461
    • (2008) Front Biosci , vol.13 , pp. 453-461
    • Martinez, F.O.1    Sica, A.2    Mantovani, A.3
  • 154
    • 70350558453 scopus 로고    scopus 로고
    • Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord
    • Kigerl KA, Gensel JC, Ankeny DP et al (2009) Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. J Neurosci 29:13435-13444
    • (2009) J Neurosci , vol.29 , pp. 13435-13444
    • Kigerl, K.A.1    Gensel, J.C.2    Ankeny, D.P.3
  • 155
    • 84859912177 scopus 로고    scopus 로고
    • Challenging the role of adaptive immunity in neurotrauma: Rag1_/_ mice lacking mature B and T cells do not show neuroprotection after closed head injury
    • Weckbach S, Neher M, Losacco JT et al (2012) Challenging the role of adaptive immunity in neurotrauma: Rag1_/_ mice lacking mature B and T cells do not show neuroprotection after closed head injury. J Neurotrauma 29:1233-1242
    • (2012) J Neurotrauma , vol.29 , pp. 1233-1242
    • Weckbach, S.1    Neher, M.2    Losacco, J.T.3
  • 156
    • 59349115909 scopus 로고    scopus 로고
    • Mechanisms and implications of adaptive immune responses after traumatic spinal cord injury
    • Ankeny DP, Popovich PG (2009) Mechanisms and implications of adaptive immune responses after traumatic spinal cord injury. Neuroscience 158:1112-1121
    • (2009) Neuroscience , vol.158 , pp. 1112-1121
    • Ankeny, D.P.1    Popovich, P.G.2
  • 157
    • 0036548768 scopus 로고    scopus 로고
    • Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy
    • Jones TB, Basso DM, Sodhi A et al (2002) Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy. J Neurosci 22:2690-2700
    • (2002) J Neurosci , vol.22 , pp. 2690-2700
    • Jones, T.B.1    Basso, D.M.2    Sodhi, A.3
  • 158
    • 0034700868 scopus 로고    scopus 로고
    • Autoimmune T cells as potential neuroprotective therapy for spinal cord injury
    • Hauben E, Nevo U, Yoles E et al (2000) Autoimmune T cells as potential neuroprotective therapy for spinal cord injury. Lancet 355:286-287
    • (2000) Lancet , vol.355 , pp. 286-287
    • Hauben, E.1    Nevo, U.2    Yoles, E.3
  • 159
    • 0034279106 scopus 로고    scopus 로고
    • Passive or active immunization with myelin basic protein promotes recovery from spinal cord contusion
    • Hauben E, Butovsky O, Nevo U et al (2000) Passive or active immunization with myelin basic protein promotes recovery from spinal cord contusion. J Neurosci 20:6421-6430
    • (2000) J Neurosci , vol.20 , pp. 6421-6430
    • Hauben, E.1    Butovsky, O.2    Nevo, U.3
  • 160
    • 69549135265 scopus 로고    scopus 로고
    • The role of the choroid plexus in neutrophil invasion after traumatic brain injury
    • Szmydynger-Chodobska J, Strazielle N, Zink BJ et al (2009) The role of the choroid plexus in neutrophil invasion after traumatic brain injury. J Cereb Blood Flow Metab 29:1503-1516
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 1503-1516
    • Szmydynger-Chodobska, J.1    Strazielle, N.2    Zink, B.J.3
  • 161
    • 84855341912 scopus 로고    scopus 로고
    • Posttraumatic invasion of monocytes across the blood-cerebrospinal fluid barrier
    • Szmydynger-Chodobska J, Strazielle N, Gandy JR et al (2012) Posttraumatic invasion of monocytes across the blood-cerebrospinal fluid barrier. J Cereb Blood Flow Metab 32:93-104
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 93-104
    • Szmydynger-Chodobska, J.1    Strazielle, N.2    Gandy, J.R.3
  • 162
    • 0029609245 scopus 로고
    • Surface attachment of Salmonella typhimurium to intestinal epithelia imprints the subepithelial matrix with gradients chemotactic for neutrophils
    • McCormick BA, Hofman PM, Kim J et al (1995) Surface attachment of Salmonella typhimurium to intestinal epithelia imprints the subepithelial matrix with gradients chemotactic for neutrophils. J Cell Biol 131:1599-1608
    • (1995) J Cell Biol , vol.131 , pp. 1599-1608
    • McCormick, B.A.1    Hofman, P.M.2    Kim, J.3
  • 163
    • 0031883544 scopus 로고    scopus 로고
    • Apical secretion of a pathogen-elicited epithelial chemoattractant activity in response to surface colonization of intestinal epithelia by Salmonella typhimurium
    • McCormick BA, Parkos CA, Colgan SP et al (1998) Apical secretion of a pathogen-elicited epithelial chemoattractant activity in response to surface colonization of intestinal epithelia by Salmonella typhimurium. J Immunol 160:455-466
    • (1998) J Immunol , vol.160 , pp. 455-466
    • McCormick, B.A.1    Parkos, C.A.2    Colgan, S.P.3
  • 164
    • 84873325652 scopus 로고    scopus 로고
    • The dual cyclooxygenase/5-lipoxygenase inhibitor licofelone attenuates p-glycoprotein-mediated drug resistance in the injured spinal cord
    • Dulin JN, Moore ML, Grill RJ (2013) The dual cyclooxygenase/5-lipoxygenase inhibitor licofelone attenuates p-glycoprotein-mediated drug resistance in the injured spinal cord. J Neurotrauma 30:211-226
    • (2013) J Neurotrauma , vol.30 , pp. 211-226
    • Dulin, J.N.1    Moore, M.L.2    Grill, R.J.3
  • 165
    • 33645340038 scopus 로고    scopus 로고
    • Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia
    • Spudich A, Kilic E, Xing H et al (2006) Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia. Nat Neurosci 9:487-488
    • (2006) Nat Neurosci , vol.9 , pp. 487-488
    • Spudich, A.1    Kilic, E.2    Xing, H.3
  • 166
    • 84873407779 scopus 로고    scopus 로고
    • Early brain injury alters the blood-brain barrier phenotype in parallel with β-amyloid and cognitive changes in adulthood
    • Pop V, Sorensen DW, Kamper JE et al (2013) Early brain injury alters the blood-brain barrier phenotype in parallel with β-amyloid and cognitive changes in adulthood. J Cereb Blood Flow Metab 33:205-214
    • (2013) J Cereb Blood Flow Metab , vol.33 , pp. 205-214
    • Pop, V.1    Sorensen, D.W.2    Kamper, J.E.3
  • 167
    • 46949098349 scopus 로고    scopus 로고
    • Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy
    • Miller DS, Bauer B, Hartz AM (2008) Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy. Pharmacol Rev 60:196-209
    • (2008) Pharmacol Rev , vol.60 , pp. 196-209
    • Miller, D.S.1    Bauer, B.2    Hartz, A.M.3
  • 168
    • 72049119592 scopus 로고    scopus 로고
    • Targeting regulation of ABC efflux transporters in brain diseases: a novel therapeutic approach
    • Potschka H (2010) Targeting regulation of ABC efflux transporters in brain diseases: a novel therapeutic approach. Pharmacol Ther 125:118-127
    • (2010) Pharmacol Ther , vol.125 , pp. 118-127
    • Potschka, H.1
  • 169
    • 34547401505 scopus 로고    scopus 로고
    • Non-selective cation channels, transient receptor potential channels and ischemic stroke
    • Simard JM, Tarasov KV, Gerzanich V (2007) Non-selective cation channels, transient receptor potential channels and ischemic stroke. Biochim Biophys Acta 1772:947-957
    • (2007) Biochim Biophys Acta , vol.1772 , pp. 947-957
    • Simard, J.M.1    Tarasov, K.V.2    Gerzanich, V.3
  • 170
    • 84873283728 scopus 로고    scopus 로고
    • The sulfonylurea receptor 1 (Sur1)-transient receptor potential melastatin 4 (Trpm4) channel
    • Woo SK, Kwon MS, Ivanov A et al (2013) The sulfonylurea receptor 1 (Sur1)-transient receptor potential melastatin 4 (Trpm4) channel. J Biol Chem 288:3655-3667
    • (2013) J Biol Chem , vol.288 , pp. 3655-3667
    • Woo, S.K.1    Kwon, M.S.2    Ivanov, A.3
  • 171
    • 84863338624 scopus 로고    scopus 로고
    • On potential interactions between non-selective cation channel TRPM4 and sulfonylurea receptor SUR1
    • Sala-Rabanal M, Wang S, Nichols CG (2012) On potential interactions between non-selective cation channel TRPM4 and sulfonylurea receptor SUR1. J Biol Chem 287:8746-8756
    • (2012) J Biol Chem , vol.287 , pp. 8746-8756
    • Sala-Rabanal, M.1    Wang, S.2    Nichols, C.G.3
  • 172
    • 33645733773 scopus 로고    scopus 로고
    • Newly expressed SUR1-regulated NCCa-ATP channel mediates cerebral edema after ischemic stroke
    • Simard JM, Chen M, Tarasov KV et al (2006) Newly expressed SUR1-regulated NCCa-ATP channel mediates cerebral edema after ischemic stroke. Nat Med 12:433-440
    • (2006) Nat Med , vol.12 , pp. 433-440
    • Simard, J.M.1    Chen, M.2    Tarasov, K.V.3
  • 173
    • 59149087488 scopus 로고    scopus 로고
    • Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage
    • Simard JM, Geng Z, Woo SK et al (2009) Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage. J Cereb Blood Flow Metab 29:317-330
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 317-330
    • Simard, J.M.1    Geng, Z.2    Woo, S.K.3
  • 174
    • 59649105028 scopus 로고    scopus 로고
    • De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury
    • Gerzanich V, Woo SK, Vennekens R et al (2009) De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury. Nat Med 15:185-191
    • (2009) Nat Med , vol.15 , pp. 185-191
    • Gerzanich, V.1    Woo, S.K.2    Vennekens, R.3
  • 175
    • 60549106649 scopus 로고    scopus 로고
    • Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke
    • Simard JM, Yurovsky V, Tsymbalyuk N et al (2009) Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke. Stroke 40:604-609
    • (2009) Stroke , vol.40 , pp. 604-609
    • Simard, J.M.1    Yurovsky, V.2    Tsymbalyuk, N.3
  • 176
    • 78650178829 scopus 로고    scopus 로고
    • Glibenclamide reduces hippocampal injury and preserves rapid spatial learning in a model of traumatic brain injury
    • Patel AD, Gerzanich V, Geng Z et al (2010) Glibenclamide reduces hippocampal injury and preserves rapid spatial learning in a model of traumatic brain injury. J Neuropathol Exp Neurol 69:1177-1190
    • (2010) J Neuropathol Exp Neurol , vol.69 , pp. 1177-1190
    • Patel, A.D.1    Gerzanich, V.2    Geng, Z.3
  • 177
    • 70449102882 scopus 로고    scopus 로고
    • In the beginning
    • Ransohoff RM (2009) In the beginning. Nature 462:41-42
    • (2009) Nature , vol.462 , pp. 41-42
    • Ransohoff, R.M.1
  • 178
    • 44949103395 scopus 로고    scopus 로고
    • Neuroprotection via matrix-trophic coupling between cerebral endothelial cells and neurons
    • Guo S, Kim WJ, Lok J et al (2008) Neuroprotection via matrix-trophic coupling between cerebral endothelial cells and neurons. Proc Natl Acad Sci U S A 105:7582-7587
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 7582-7587
    • Guo, S.1    Kim, W.J.2    Lok, J.3
  • 179
    • 66149111387 scopus 로고    scopus 로고
    • Rac1 is a critical mediator of endotheliumderived neurotrophic activity
    • Sawada N, Kim HH, Moskowitz MA et al (2009) Rac1 is a critical mediator of endotheliumderived neurotrophic activity. Sci Signal 2:ra10
    • (2009) Sci Signal , vol.2 , pp. ra10
    • Sawada, N.1    Kim, H.H.2    Moskowitz, M.A.3


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