COG1410 improves cognitive performance and reduces cortical neuronal loss in the traumatically injured brain

Journal of Neurotrauma

Volumn 26, Issue 1, 2009, Pages 121-129

  Hoane, Michael R ^a   Kaufman, Nicholas ^a   Vitek, Michael P ^b,c   McKenna, Suzanne E ^b  

^a SOUTHERN ILLINOIS UNIVERSITY   (United States)

^b Optimal Screening Vehicles Division   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

apoE; Behavioral recovery; Neuronal degeneration; Neuroprotection; Recovery of function; TBI; Trauma

Indexed keywords

APOLIPOPROTEIN E; COG 1410; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; FRONTAL CORTEX; HISTOPATHOLOGY; MALE; MAZE TEST; MENTAL PERFORMANCE; MENTAL TASK; MOTOR ACTIVITY; NERVE CELL DEGENERATION; NONHUMAN; RAT; REFERENCE MEMORY; SENSORIMOTOR NEUROPATHY; TRAUMATIC BRAIN INJURY; WORKING MEMORY;

ANIMALS; APOLIPOPROTEINS E; BRAIN INJURIES; CEREBRAL CORTEX; COGNITION DISORDERS; COLORING AGENTS; DISEASE MODELS, ANIMAL; FLUORESCEINS; INJECTIONS, INTRAVENOUS; MALE; MAZE LEARNING; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; TREATMENT OUTCOME;

EID: 59849124156     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2008.0565     Document Type: Article

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