Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states

Neurobiology of Aging

Volumn 34, Issue 5, 2013, Pages 1397-1411

  Kumar, Alok ^a   Stoica, Bogdan A ^a   Sabirzhanov, Boris ^a   Burns, Mark P ^b   Faden, Alan I ^a   Loane, David J ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Aging; Alternative activation; Microglia macrophage; NADPH oxidase; Neurodegeneration; Traumatic brain injury; Ym1

Indexed keywords

BIOLOGICAL MARKER; CHITINASE; CHITINASE3 LIKE 3 PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG;

AGING; ANIMAL TISSUE; ARTICLE; BRAIN CONTUSION; BRAIN CORTEX; CELL ACTIVATION; CELL LOSS; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INJURY SEVERITY; MACROPHAGE; MALE; MICROGLIA; MOUSE; NERVE DEGENERATION; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEREOMETRY; THALAMUS; TRAUMATIC BRAIN INJURY; UPREGULATION;

AGING; ANIMALS; BRAIN; BRAIN INJURIES; CELLS, CULTURED; CHRONIC DISEASE; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICROGLIA;

EID: 84873452455     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2012.11.013     Document Type: Article

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