Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression

Journal of Biological Chemistry

Volumn 281, Issue 4, 2006, Pages 2120-2127

  Hu, Kebin ^a   Yang, Junwei ^b   Tanaka, Sakae ^c   Gonias, Steven L ^d   Mars, Wendy M ^a   Liu, Youhua ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b NANJING MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MATERIALS; CELL MEMBRANES; CYTOLOGY; ENZYMES; GENETIC ENGINEERING; TISSUE CULTURE;

NON-ENZYMATIC MUTANT; PLASMINOGENS; RECEPTOR-ASSOCIATED PROTEINS; SERINE PROTEASE;

PROTEINS;

CYTOKINE; GELATINASE B; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MEMBRANE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PROTEIN SUBUNIT; TISSUE PLASMINOGEN ACTIVATOR; GELATIN; LOW DENSITY LIPOPROTEIN RECEPTOR; LRP1 PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN; TYROSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MUTANT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; FIBROBLAST; GENE EXPRESSION; GENE OVEREXPRESSION; KIDNEY INTERSTITIUM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; RAT; SIGNAL TRANSDUCTION; WILD TYPE; ADENOVIRUS; ANIMAL; BINDING COMPETITION; BIOSYNTHESIS; CELL LINE; CELL MEMBRANE; CELL NUCLEUS; CHEMISTRY; FLUORESCENCE MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; HOMOZYGOTE; IMMUNOPRECIPITATION; KIDNEY; METABOLISM; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

PISUM SATIVUM;

ADENOVIRIDAE; ANIMALS; BINDING, COMPETITIVE; BLOTTING, WESTERN; CELL LINE; CELL MEMBRANE; CELL NUCLEUS; CYTOKINES; ENZYME ACTIVATION; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GELATIN; GENE EXPRESSION REGULATION; HOMOZYGOTE; IMMUNOPRECIPITATION; KIDNEY; MALE; MAP KINASE KINASE 1; MATRIX METALLOPROTEINASE 9; MICE; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; RATS; RECEPTORS, LDL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TISSUE PLASMINOGEN ACTIVATOR; TUMOR SUPPRESSOR PROTEINS; TYROSINE;

EID: 33644869414     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M504988200     Document Type: Article

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