Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury

Journal of Neurochemistry

Volumn 102, Issue 1, 2007, Pages 37-50

  Kigerl, Kristina A ^a,b   Lai, Wenmin ^a,b   Rivest, Serge ^c   Hart, Ronald P ^d   Satoskar, Abhay R ^a,b   Popovich, Phillip G ^a,b,e  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c LAVAL UNIVERSITY   (Canada)

^d RUTGERS UNIVERSITY   (United States)

^e Center for Brain and Spinal Cord Repair   (United States)

Author keywords

Macrophage; Microglia; Neuroinflammation; Spinal cord injury; Toll like receptors

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; MUTANT PROTEIN; MYELIN; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 7;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; CONTROLLED STUDY; CONVALESCENCE; CYTOKINE PRODUCTION; DEMYELINATION; FEMALE; FUNCTIONAL ASSESSMENT; GLIOSIS; IN VIVO STUDY; KNOCKOUT MOUSE; LOCOMOTION; MACROPHAGE ACTIVATION; MOTOR DYSFUNCTION; MOUSE; MYELITIS; NEUROPATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; RNA ANALYSIS; SIGNAL TRANSDUCTION; SPINAL CORD INJURY; WHITE MATTER; WILD TYPE;

ANIMALS; AXONS; CHEMOKINES; CYTOKINES; FEMALE; GLIOSIS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFLAMMATION; LOCOMOTION; MACROPHAGES; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICRODISSECTION; MYELIN SHEATH; NITRIC OXIDE SYNTHASE TYPE II; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SPINAL CORD INJURIES; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

MUS;

EID: 34250182782     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04524.x     Document Type: Article

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