Effects of aging on blood brain barrier and matrix metalloproteases following controlled cortical impact in mice

Experimental Neurology

Volumn 234, Issue 1, 2012, Pages 50-61

  Lee, Phil ^a,b   Kim, Jieun ^a   Williams, Rachel ^b   Sandhir, Rajat ^b   Gregory, Eugene ^b   Brooks, William M ^a,b   Berman, Nancy E J ^b  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Blood brain barrier; Claudin 5; Controlled cortical impact; MMP 2; MMP 9; Occludin; T1 mapping; Traumatic brain injury; ZO 1

Indexed keywords

CLAUDIN 5; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN G; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; MESSENGER RNA; OCCLUDIN; PROTEIN ZO1;

ADULT ANIMAL; AGE; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN INJURY; CONTROLLED STUDY; ENZYME ACTIVATION; GENE; GENE EXPRESSION; MALE; MATRIX METALLOPROTEINASE 9 GENE; MEMBRANE PERMEABILITY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRAUMATIC BRAIN INJURY;

AGING; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN INJURIES; BRAIN MAPPING; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; GADOLINIUM DTPA; GENE EXPRESSION REGULATION; MAGNETIC RESONANCE IMAGING; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; PERMEABILITY; PHOSPHOPROTEINS; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASES; TRAUMA SEVERITY INDICES;

EID: 84862793270     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2011.12.016     Document Type: Article

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