Apolipoprotein E expression after spinal cord injury in the mouse

Journal of Neuroscience Research

Volumn 71, Issue 3, 2003, Pages 417-426

  Seitz, Alexander ^a   Kragol, Maja ^a   Aglow, Elsa ^a   Showe, Louise ^a   Heber Katz, Ellen ^a  

^a WISTAR INSTITUTE   (United States)

Author keywords

Apolipoprotein E; B6 mouse; Macrophages; Neutrophils; Spinal cord injury

Indexed keywords

APOLIPOPROTEIN E; MESSENGER RNA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FEMALE; HISTOLOGY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MOUSE; NERVOUS SYSTEM INJURY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; SPINAL CORD INJURY; SPINAL CORD TRANSSECTION;

ANIMALS; APOLIPOPROTEINS E; BRAIN; FEMALE; MICE; MICE, INBRED C57BL; RNA; SPINAL CORD; SPINAL CORD INJURIES;

EID: 0037311388     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10482     Document Type: Article

References (37)

1. Bandtlow CE, Schwab ME. 2000. NI-35/250/nogo-a: a neurite growth inhibitor restricting structural plasticity and regeneration of nerve fibers in the adult vertebrate CNS [in process citation]. Glia 29:175-181.
2. Barger SW, Harmon AD. 1997. Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E. Nature 388:878-881.
3. Boyles JK, Pitas RE, Wilson E, Mahley RW, Taylor JM. 1985. Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. J Clin Invest 76:1501-1513.
4. Cadelli DS, Schwab ME. 1991. Myelin-associated inhibitors of neurite outgrowth and their role in CNS regeneration. Ann N Y Acad Sci 633:234-240.
5. Davies SJ, Goucher DR, Doller C, Silver J. 1999. Robust regeneration of adult sensory axons in degenerating white matter of the adult rat spinal cord. J Neurosci 19:5810-5822.
6. Driscoll DM, Getz GS. 1984. Extrahepatic synthesis of apolipoprotein E. J Lipid Res 25:1368-1379.
7. Ellegala DB, Tassone JC, Avellino AM, Pekow CA, Cunningham ML, Kliot M. 1996. Dorsal laminectomy in the adult mouse: a model for nervous system research. Lab Anim Sci 46:86-89.
8. Elshourbagy NA, Liao WS, Mahley RW, Taylor JM. 1985. Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets. Proc Natl Acad Sci USA 82:203-207.
9. Fagan AM, Holtzman DM. 2000. Astrocyte lipoproteins, effects of apoE on neuronal function, and role of apoE in amyloid-beta deposition in vivo. Microsc Res Techn 50:297-304.
10. Horsburgh K, McCulloch J, Nilsen M, McCracken E, Large C, Roses AD, Nicoll JA. 2000a. Intraventricular infusion of apolipoprotein E ameliorates acute neuronal damage after global cerebral ischemia in mice. J Cereb Blood Flow Metab 20:458-462.
11. Horsburgh K, McCulloch J, Nilsen M, Roses AD, Nicoll JA. 2000b. Increased neuronal damage and apoE immunoreactivity in human apolipoprotein E, E4 isoform-specific, transgenic mice after global cerebral ischaemia. Eur J Neurosci 12:4309-4317.
12. Hui DY, Harmony JA, Innerarity TL, Mahley RW. 1980. Immunoregulatory plasma lipoproteins. Role of apoprotein E and apoprotein B. J Biol Chem 255:11775-11781.
13. Katoh S, Ikata T, Tsubo M, Hamada Y, el Masry WS. 1997. Possible implication of leukocytes in secondary pathological changes after spinal cord injury. Injury 28:215-217.
14. Kelly ME, Clay MA, Mistry MJ, Hsieh-Li HM, Harmony JA. 1994. Apolipoprotein E inhibition of proliferation of mitogen-activated T lymphocytes: production of interleukin 2 with reduced biological activity. Cell Immunol 159:124-139.
15. Kuhn PL, Wrathall JR. 1998. A mouse model of graded contusive spinal cord injury. J Neurotrauma 15:125-140.
16. Laskowitz DT, Thekdi AD, Thekdi SD, Han SK, Myers JK, Pizzo SV, Bennett ER. 2001. Downregulation of microglial activation by apolipoprotein E and apoE-mimetic peptides. Exp Neurol 167:74-85.
17. Lynch JR, Morgan D, Mance J, Matthew WD, Laskowitz DT. 2001. Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response. J Neuroimmunol 114:107-113.
18. Ma M, Basso DM, Walters P, Stokes BT, Jakeman LB. 2001. Behavioral and histological outcomes following graded spinal cord contusion injury in the C57B1/6 mouse. Exp Neurol 169:239-254.
19. Mahley RW. 1988. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 240:622-630.
20. Metzger RE, LaDu MJ, Pan JB, Getz GS, Frail DE, Falduto MT. 1996. Neurons of the human frontal cortex display apolipoprotein E immunoreactivity: implications for Alzheimer's disease. J Neuropathol Exp Neurol 55:372-380.
21. Mistry MJ, Clay MA, Kelly ME, Steiner MA, Harmony JA. 1995. Apolipoprotein E restricts interleukin-dependent T lymphocyte proliferation at the G1A/G1B boundary. Cell Immunol 160:14-23.
22. Nakai M, Kawamata T, Taniguchi T, Maeda K, Tanaka C. 1996. Expression of apolipoprotein E mRNA in rat microglia. Neurosci Lett 211:41-44.
23. Nathan BP, Bellosta S, Sanan DA, Weisgraber KH, Mahley RW, Pitas RE. 1994. Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro. Science 264:850-852.
24. Nathan BP, Chang KC, Bellosta S, Brisch E, Ge N, Mahley RW, Pitas RE. 1995. The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization. J Biol Chem 270:19791-19799.
25. Nawashiro H, Messing A, Azzam N, Brenner M. 1998. Mice lacking GFAP are hypersensitive to traumatic cerebrospinal injury. Neuroreport 9:1691-1696.
26. Pepe MG, Curtiss LK. 1986. Apolipoprotein E is a biologically active constituent of the normal immunoregulatory lipoprotein, LDL-In. J Immunol 136:3716-3723.
27. Raivich G, Haas S, Werner A, Klein MA, Kloss C, Kreutzberg GW. 1998. Regulation of MCSF receptors on microglia in the normal and injured mouse central nervous system: a quantitative immunofluorescence study using confocal laser microscopy. J Comp Neurol 395:342-358.
28. Seitz A, Aglow E, Heber-Katz E. 2002. Recovery from spinal cord injury: a new transection model in the C57B1/6 mouse. J Neurosci Res 67:337-345.
29. Stoll G, Muller HW. 1986. Macrophages in the peripheral nervous system and astroglia in the central nervous system of rat commonly express apolipoprotein E during development but differ in their response to injury. Neurosci Lett 72:233-238.
30. Stone DJ, Rozovsky I, Morgan TE, Anderson CP, Hajian H, Finch CE. 1997. Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro. Exp Neurol 143:313-318.
31. Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD. 1993. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 90:1977-1981.
32. Swertfeger DK, Hui DY. 2001. Apolipoprotein E: a cholesterol transport protein with lipid transport independent cell signaling properties. Front Biosci 6:D526-D535.
33. Taoka Y, Okajima K. 2000. Role of leukocytes in spinal cord injury in rats. J Neurotrauma 17:219-229.
34. Taoka Y, Okajima K, Uchiba M, Murakami K, Kushimoto S, Johno M, Naruo M, Okabe H, Takatsuki K. 1997. Role of neutrophils in spinal cord injury in the rat. Neuroscience 79:1177-1182.
35. Tesseur I, Van Dorpe J, Bruynseels K, Bronfman F, Sciot R, Van Lommel A, Van Leuven F. 2000. Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord. Am J Pathol 157:1495-1510.
36. Wittwer CT, Ririe KM, Andrew RV, David DA, Gundry PA, Balis UJ. 1997. The LightCycler: a microvolume multisample fluorimeter with rapid temperature control. Biotechniques 22:176-181.
37. Zhang Z, Guth L, Steward O. 1998. Mechanisms of motor recovery after subtotal spinal cord injury: insights from the study of mice carrying a mutation (Wlds) that delays cellular responses to injury. Exp Neurol 149:221-229.