Traveling the vitamin B12 pathway: Oral delivery of protein and peptide drugs

Angewandte Chemie - International Edition

Volumn 48, Issue 6, 2009, Pages 1022-1028

  Petrus, Amanda K ^a   Fairchild, Timothy J ^a   Doyle, Robert P ^a  

^a SYRACUSE UNIVERSITY   (United States)

Author keywords

Bioconjugates; Drug delivery; Medicinal chemistry; Proteins peptides; Vitamin B12

Indexed keywords

BIOMOLECULES; DRUG DELIVERY; DRUG PRODUCTS; LIGANDS; PROTEINS;

ABSORPTION MECHANISMS; BIOCONJUGATES; COLONY-STIMULATING FACTORS; INTESTINAL LUMINA; MEDICINAL CHEMISTRY; ORAL DELIVERIES; ORAL ROUTES; PATIENT COMPLIANCES; PEPTIDE DRUGS; PEPTIDE THERAPEUTICS; PROTEIN DELIVERIES; PROTEINS/PEPTIDES; PROTEOLYTIC DEGRADATIONS; RECENT PROGRESS; THERAPEUTIC PEPTIDES; VITAMIN B12;

AMINES;

CYANOCOBALAMIN; INSULIN; NANOPARTICLE; PEPTIDE; PROTEIN; TRANSCOBALAMIN;

ANIMAL; BLOOD; CHEMISTRY; METABOLISM; ORAL DRUG ADMINISTRATION; PROTEIN TERTIARY STRUCTURE; RAT; REVIEW; SYNTHESIS;

ADMINISTRATION, ORAL; ANIMALS; INSULIN; NANOPARTICLES; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RATS; TRANSCOBALAMINS; VITAMIN B 12;

EID: 59049088260     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200800865     Document Type: Short Survey

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