-
1
-
-
15444362906
-
Local conformational fluctuations can modulate the coupling between proton binding and global structural transitions in proteins
-
Whitten, S. T., Garcia-Moreno, E. B. & Hilser, V. J. Local conformational fluctuations can modulate the coupling between proton binding and global structural transitions in proteins. Proc. Natl Acad. Sci. USA 102, 4282-4287 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 4282-4287
-
-
Whitten, S.T.1
Garcia-Moreno, E.B.2
Hilser, V.J.3
-
4
-
-
54449084614
-
Carbon dioxide transport through membranes
-
Missner, A. et al. Carbon dioxide transport through membranes. J. Biol. Chem. 283, 25340-25347 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 25340-25347
-
-
Missner, A.1
-
6
-
-
35448946098
-
Vacuolar ATPases: Rotary proton pumps in physiology and pathophysiology
-
Forgac, M. Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology. Nature Rev. Mol. Cell Biol. 8, 917-929 (2007).
-
(2007)
Nature Rev. Mol. Cell Biol.
, vol.8
, pp. 917-929
-
-
Forgac, M.1
-
7
-
-
62149116051
-
The gastric HK-ATPase: Structure, function, and inhibition
-
Shin, J. M., Munson, K., Vagin, O. & Sachs, G. The gastric HK-ATPase: structure, function, and inhibition. Pflugers Arch. 457, 609-622 (2009).
-
(2009)
Pflugers Arch.
, vol.457
, pp. 609-622
-
-
Shin, J.M.1
Munson, K.2
Vagin, O.3
Sachs, G.4
-
8
-
-
66449088593
-
Regulation of the V-ATPase in kidney epithelial cells: Dual role in acid-base homeostasis and vesicle trafficking
-
Brown, D., Paunescu, T. G., Breton, S. & Marshansky, V. Regulation of the V-ATPase in kidney epithelial cells: dual role in acid-base homeostasis and vesicle trafficking. J. Exp. Biol. 212, 1762-1772 (2009).
-
(2009)
J. Exp. Biol.
, vol.212
, pp. 1762-1772
-
-
Brown, D.1
Paunescu, T.G.2
Breton, S.3
Marshansky, V.4
-
9
-
-
12144271044
-
Evolutionary origins of eukaryotic sodium/proton exchangers. Am. J. Physiol
-
Brett, C. L., Donowitz, M. & Rao, R. Evolutionary origins of eukaryotic sodium/proton exchangers. Am. J. Physiol., Cell Physiol. 288, C223-C239 (2005).
-
(2005)
Cell Physiol.
, vol.288
-
-
Brett, C.L.1
Donowitz, M.2
Rao, R.3
-
10
-
-
34547963769
-
Emerging roles of alkali cation/proton exchangers in organellar homeostasis
-
Orlowski, J. & Grinstein, S. Emerging roles of alkali cation/proton exchangers in organellar homeostasis. Curr. Opin. Cell Biol. 19, 483-492 (2007).
-
(2007)
Curr. Opin. Cell Biol.
, vol.19
, pp. 483-492
-
-
Orlowski, J.1
Grinstein, S.2
-
11
-
-
0027500849
-
+ antiport: Assessment of effects on intracellular pH
-
+ antiport: Assessment of effects on intracellular pH. EMBO J. 12, 5209-5218 (1993).
-
(1993)
EMBO J.
, vol.12
, pp. 5209-5218
-
-
Grinstein, S.1
-
12
-
-
0027139644
-
+ exchanger isoform of renal brush border
-
+ exchanger isoform of renal brush border. Am. J. Physiol. 265, F736-F742 (1993).
-
(1993)
Am. J. Physiol.
, vol.265
-
-
Biemesderfer, D.1
-
15
-
-
0034019238
-
+ exchange activities mediated by apical NHE2 and basolateral NHE4 isoforms
-
+ exchange activities mediated by apical NHE2 and basolateral NHE4 isoforms. Am. J. Physiol. 278, F452-F463 (2000).
-
(2000)
Am. J. Physiol.
, vol.278
-
-
Peti-Peterdi, J.1
-
16
-
-
0021894461
-
Kinetic properties of the plasma membrane Na-H exchanger
-
Aronson, P. S. Kinetic properties of the plasma membrane Na-H exchanger. Annu. Rev. Physiol. 47, 545-560 (1985).
-
(1985)
Annu. Rev. Physiol.
, vol.47
, pp. 545-560
-
-
Aronson, P.S.1
-
17
-
-
53549110255
-
Steady-state function of the ubiquitous mammalian Na/H exchanger (NHE1) in relation to dimer coupling models with 2Na/2H stoichiometry
-
Fuster, D., Moe, O. W. & Hilgemann, D. W. Steady-state function of the ubiquitous mammalian Na/H exchanger (NHE1) in relation to dimer coupling models with 2Na/2H stoichiometry. J. Gen. Physiol. 132, 465-480 (2008).
-
(2008)
J. Gen. Physiol.
, vol.132
, pp. 465-480
-
-
Fuster, D.1
Moe, O.W.2
Hilgemann, D.W.3
-
19
-
-
0026722914
-
Proton dependence of the partial reactions of the sodium-proton exchanger in renal brush border membranes
-
Otsu, K., Kinsella, J. L., Koh, E. & Froehlich, J. P. Proton dependence of the partial reactions of the sodium-proton exchanger in renal brush border membranes. J. Biol. Chem. 267, 8089-8096 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 8089-8096
-
-
Otsu, K.1
Kinsella, J.L.2
Koh, E.3
Froehlich, J.P.4
-
21
-
-
68049148763
-
Combined computational and biochemical study reveals the importance of electrostatic interactions between the "pH sensor" and the cation binding site of the sodium/proton antiporter NhaA of Escherichia coli
-
Olkhova, E., Kozachkov, L., Padan, E. & Michel, H. Combined computational and biochemical study reveals the importance of electrostatic interactions between the "pH sensor" and the cation binding site of the sodium/proton antiporter NhaA of Escherichia coli. Proteins 76, 548-559 (2009).
-
(2009)
Proteins
, vol.76
, pp. 548-559
-
-
Olkhova, E.1
Kozachkov, L.2
Padan, E.3
Michel, H.4
-
22
-
-
34250331233
-
The influence of protonation states on the dynamics of the NhaA antiporter from Escherichia coli
-
Olkhova, E., Padan, E. & Michel, H. The influence of protonation states on the dynamics of the NhaA antiporter from Escherichia coli. Biophys. J. 92, 3784-3791 (2007).
-
(2007)
Biophys. J.
, vol.92
, pp. 3784-3791
-
-
Olkhova, E.1
Padan, E.2
Michel, H.3
-
26
-
-
1242321029
-
A mechanism for the activation of the Na/H exchanger NHE-1 by cytoplasmic acidification and mitogens
-
Lacroix, J., Poet, M., Maehrel, C. & Counillon, L. A mechanism for the activation of the Na/H exchanger NHE-1 by cytoplasmic acidification and mitogens. EMBO Rep. 5, 91-96 (2004).
-
(2004)
EMBO Rep.
, vol.5
, pp. 91-96
-
-
Lacroix, J.1
Poet, M.2
Maehrel, C.3
Counillon, L.4
-
27
-
-
78651189765
-
On the nature of allosteric transitions: A plausible model
-
Monod, J., Wyman, J. & Changeux, J. P. On the nature of allosteric transitions: a plausible model. J. Mol. Biol. 12, 88-118 (1965).
-
(1965)
J. Mol. Biol.
, vol.12
, pp. 88-118
-
-
Monod, J.1
Wyman, J.2
Changeux, J.P.3
-
28
-
-
33847122150
-
+ exchanger isoform 1 phosphorylation and activity by 90-kDa ribosomal S6 kinase (RSK): Effects of the novel and specific RSK inhibitor fmk on responses to α1-adrenergic stimulation
-
+ exchanger isoform 1 phosphorylation and activity by 90-kDa ribosomal S6 kinase (RSK): effects of the novel and specific RSK inhibitor fmk on responses to α1-adrenergic stimulation. Mol. Pharmacol. 71, 799-806 (2007).
-
(2007)
Mol. Pharmacol.
, vol.71
, pp. 799-806
-
-
Cuello, F.1
Snabaitis, A.K.2
Cohen, M.S.3
Taunton, J.4
Avkiran, M.5
-
29
-
-
0034780077
-
Trophic factor withdrawal: P38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization
-
Khaled, A. R. et al. Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization. Mol. Cell. Biol. 21, 7545-7557 (2001).
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7545-7557
-
-
Khaled, A.R.1
-
30
-
-
34250378750
-
+ exchanger is mediated through phosphorylation of amino acids Ser770 and Ser771
-
+ exchanger is mediated through phosphorylation of amino acids Ser770 and Ser771. J. Biol. Chem. 282, 6292-6299 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 6292-6299
-
-
Malo, M.E.1
Li, L.2
Fliegel, L.3
-
31
-
-
0033575236
-
+ exchanger isoform-1
-
+ exchanger isoform-1. J. Biol. Chem. 274, 20206-20214 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20206-20214
-
-
Takahashi, E.1
-
32
-
-
0032541338
-
P160ROCK mediates RhoA activation of Na-H exchange
-
Tominaga, T., Ishizaki, T., Narumiya, S. & Barber, D. L. p160ROCK mediates RhoA activation of Na-H exchange. EMBO J. 17, 4712-4722 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 4712-4722
-
-
Tominaga, T.1
Ishizaki, T.2
Narumiya, S.3
Barber, D.L.4
-
33
-
-
0035903087
-
+ exchanger NHE1 and regulates NHE1 activation by platelet-derived growth factor
-
+ exchanger NHE1 and regulates NHE1 activation by platelet-derived growth factor. J. Biol. Chem. 276, 31349-31356 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31349-31356
-
-
Yan, W.H.1
Nehrke, K.2
Choi, J.3
Barber, D.L.4
-
34
-
-
0034631854
-
+ exchange requires phosphatidylinositol 4, 5-bisphosphate
-
+ exchange requires phosphatidylinositol 4, 5-bisphosphate. J.Cell Biol. 150, 213-224 (2000).
-
(2000)
J.Cell Biol.
, vol.150
, pp. 213-224
-
-
Aharonovitz, O.1
-
35
-
-
0028242352
-
+ exchanger isoform 1 (NHE1) is a novel member of the calmodulin-binding proteins. Identification and characterization of calmodulin-binding sites
-
+ exchanger isoform 1 (NHE1) is a novel member of the calmodulin-binding proteins. Identification and characterization of calmodulin-binding sites. J. Biol. Chem. 269, 13703-13709 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13703-13709
-
-
Bertrand, B.1
Wakabayashi, S.2
Ikeda, T.3
Pouysségur, J.4
Shigekawa, M.5
-
37
-
-
0041766292
-
+ exchangers-binding protein, is expressed in intestinal epithelium
-
+ exchangers-binding protein, is expressed in intestinal epithelium. Biol. Pharm. Bull. 26, 148-155 (2003).
-
(2003)
Biol. Pharm. Bull.
, vol.26
, pp. 148-155
-
-
Inoue, H.1
-
39
-
-
33144457846
-
A novel carbonic anhydrase II binding site regulates NHE1 activity
-
Li, X., Liu, Y., Alvarez, B. V., Casey, J. R. & Fliegel, L. A novel carbonic anhydrase II binding site regulates NHE1 activity. Biochemistry 45, 2414-2424 (2006).
-
(2006)
Biochemistry
, vol.45
, pp. 2414-2424
-
-
Li, X.1
Liu, Y.2
Alvarez, B.V.3
Casey, J.R.4
Fliegel, L.5
-
40
-
-
0029981094
-
A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange
-
Lin, X. & Barber, D. L. A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange. Proc. Nat. Acad. Sci. USA 93, 12631-12636 (1996).
-
(1996)
Proc. Nat. Acad. Sci. USA
, vol.93
, pp. 12631-12636
-
-
Lin, X.1
Barber, D.L.2
-
44
-
-
34250683573
-
Beyond ion translocation: Structural functions of the sodium-hydrogen exchanger isoform-1
-
Meima, M. E., Mackley, J. R. & Barber, D. L. Beyond ion translocation: structural functions of the sodium-hydrogen exchanger isoform-1. Curr. Opin. Nephrol. Hypertens. 16, 365-372 (2007).
-
(2007)
Curr. Opin. Nephrol. Hypertens.
, vol.16
, pp. 365-372
-
-
Meima, M.E.1
MacKley, J.R.2
Barber, D.L.3
-
45
-
-
0037164808
-
Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1
-
Denker, S. P. & Barber, D. L. Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1. J. Cell Biol. 159, 1087-1096 (2002).
-
(2002)
J. Cell Biol.
, vol.159
, pp. 1087-1096
-
-
Denker, S.P.1
Barber, D.L.2
-
46
-
-
33744832157
-
Role of the Na/H exchanger NHE1 in cell migration
-
Stock, C. & Schwab, A. Role of the Na/H exchanger NHE1 in cell migration. Acta Physiol (Oxf.) 187, 149-157 (2006).
-
(2006)
Acta Physiol (Oxf.)
, vol.187
, pp. 149-157
-
-
Stock, C.1
Schwab, A.2
-
47
-
-
39349109047
-
+ exchange and pH regulation in the control of neutrophil chemokinesis and chemotaxis
-
+ exchange and pH regulation in the control of neutrophil chemokinesis and chemotaxis. Am. J. Physiol., Cell Physiol. 294, C526-C534 (2008).
-
(2008)
Am. J. Physiol., Cell Physiol.
, vol.294
-
-
Hayashi, H.1
-
48
-
-
18544363096
-
A developmentally regulated Na-H exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis
-
Patel, H. & Barber, D. L. A developmentally regulated Na-H exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis. J. Cell Biol. 169, 321-329 (2005).
-
(2005)
J. Cell Biol.
, vol.169
, pp. 321-329
-
-
Patel, H.1
Barber, D.L.2
-
49
-
-
0028100685
-
+ exchanger stably expressed in Chinese hamster ovary cells: ATP dependence, osmotic sensitivity and role in cell proliferation
-
+ exchanger stably expressed in Chinese hamster ovary cells: ATP dependence, osmotic sensitivity and role in cell proliferation. J. Biol. Chem. 269, 23544-23552 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 23544-23552
-
-
Kapus, A.1
Grinstein, S.2
Wasan, S.3
Kandasamy, R.A.4
Orlowski, J.5
-
51
-
-
0242582266
-
Na-H exchange-dependent increase in intracellular pH times G2/M entry and transition
-
Putney, L. K. & Barber, D. L. Na-H exchange-dependent increase in intracellular pH times G2/M entry and transition. J. Biol. Chem. 278, 44645-44649 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 44645-44649
-
-
Putney, L.K.1
Barber, D.L.2
-
52
-
-
1242340302
-
The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond
-
Halestrap, A. & Meredith, D. The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Pflugers Arch. 477, 619-628 (2004).
-
(2004)
Pflugers Arch.
, vol.477
, pp. 619-628
-
-
Halestrap, A.1
Meredith, D.2
-
54
-
-
62149122686
-
3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG
-
3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG. Proc. Natl Acad. Sci. USA 106, 5406-5411 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 5406-5411
-
-
Musa-Aziz, R.1
Chen, L.M.2
Pelletier, M.F.3
Boron, W.F.4
-
55
-
-
0034723202
-
Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes
-
Yang, B. et al. Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes. J. Biol. Chem. 275, 2686-2692 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2686-2692
-
-
Yang, B.1
-
56
-
-
58249090515
-
Bicarbonate transport in cell physiology and disease
-
Cordat, E. & Casey, J. R. Bicarbonate transport in cell physiology and disease. Biochem. J. 417, 423-439 (2009).
-
(2009)
Biochem. J.
, vol.417
, pp. 423-439
-
-
Cordat, E.1
Casey, J.R.2
-
57
-
-
0035868935
-
The stoichiometry of the electrogenic sodium bicarbonate cotransporter NBC1 is cell-type dependent
-
Gross, E. et al. The stoichiometry of the electrogenic sodium bicarbonate cotransporter NBC1 is cell-type dependent. J. Physiol. 531, 597-603 (2001).
-
(2001)
J. Physiol.
, vol.531
, pp. 597-603
-
-
Gross, E.1
-
59
-
-
66449105833
-
+-independent SLC4 anion exchangers
-
+- independent SLC4 anion exchangers. J. Exp. Biol. 212, 1672-1683 (2009).
-
(2009)
J. Exp. Biol.
, vol.212
, pp. 1672-1683
-
-
Alper, S.L.1
-
60
-
-
0033571054
-
Transport activity of AE3 chloride/bicarbonate anion-exchange proteins and their regulation by intracellular pH
-
Sterling, D. & Casey, J. R. Transport activity of AE3 chloride/bicarbonate anion-exchange proteins and their regulation by intracellular pH. Biochem. J. 344, 221-229 (1999).
-
(1999)
Biochem. J.
, vol.344
, pp. 221-229
-
-
Sterling, D.1
Casey, J.R.2
-
61
-
-
0028150719
-
Functional characterization and regulation by pH of murine AE2 anion exchanger expressed in Xenopus oocytes. Am. J. Physiol
-
Humphreys, B. D., Jiang, L., Chernova, M. N. & Alper, S. L. Functional characterization and regulation by pH of murine AE2 anion exchanger expressed in Xenopus oocytes. Am. J. Physiol., Cell Physiol. 267, C1295-C1307 (1994).
-
(1994)
Cell Physiol.
, vol.267
-
-
Humphreys, B.D.1
Jiang, L.2
Chernova, M.N.3
Alper, S.L.4
-
62
-
-
3142683762
-
- exchanger are achlorhydric
-
- exchanger are achlorhydric. J. Biol. Chem. 279, 30531-30539 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 30531-30539
-
-
Gawenis, L.R.1
-
63
-
-
0037291973
-
CFTR and bicarbonate secretion by epithelial cells
-
Hug, M. J., Tamada, T. & Bridges, R. J. CFTR and bicarbonate secretion by epithelial cells. News Physiol. Sci. 18, 38-42 (2003).
-
(2003)
News Physiol. Sci.
, vol.18
, pp. 38-42
-
-
Hug, M.J.1
Tamada, T.2
Bridges, R.J.3
-
64
-
-
18744409048
-
- transport in cystic fibrosis
-
- transport in cystic fibrosis. EMBO J. 21, 5662-5672 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 5662-5672
-
-
Ko, S.B.1
-
67
-
-
16144368521
-
Mutations of the Down-regulated in adenoma (DRA) gene cause congenital chloride diarrhoea
-
Hoglund, P. et al. Mutations of the Down-regulated in adenoma (DRA) gene cause congenital chloride diarrhoea. Nature Genet. 14, 316-319 (1996).
-
(1996)
Nature Genet.
, vol.14
, pp. 316-319
-
-
Hoglund, P.1
-
68
-
-
72949097303
-
-
(ed. Kehlenbach, R.) (Landes Bioscience, Austin)
-
Goldfarb, D. S. in Nuclear Transport (ed. Kehlenbach, R.) (Landes Bioscience, Austin, 2009).
-
(2009)
Nuclear Transport
-
-
Goldfarb, D.S.1
-
69
-
-
39649119621
-
The pH of the secretory pathway: Measurement, determinants, and regulation
-
Paroutis, P., Touret, N. & Grinstein, S. The pH of the secretory pathway: measurement, determinants, and regulation. Physiology (Bethesda) 19, 207-215 (2004).
-
(2004)
Physiology (Bethesda)
, vol.19
, pp. 207-215
-
-
Paroutis, P.1
Touret, N.2
Grinstein, S.3
-
71
-
-
46349090602
-
Structure and regulation of the vacuolar ATPases
-
Cipriano, D. J. et al. Structure and regulation of the vacuolar ATPases. Biochim. Biophys. Acta 1777, 599-604 (2008).
-
(2008)
Biochim. Biophys. Acta
, vol.1777
, pp. 599-604
-
-
Cipriano, D.J.1
-
72
-
-
0027763241
-
Defective acidification of the biosynthetic pathway in cystic fibrosis
-
Barasch, J. & al-Awqati, Q. Defective acidification of the biosynthetic pathway in cystic fibrosis. J. Cell Sci. Suppl. 17, 229-233 (1993).
-
(1993)
J. Cell Sci. Suppl.
, vol.17
, pp. 229-233
-
-
Barasch, J.1
Al-Awqati, Q.2
-
73
-
-
0029984180
-
Evidence against defective trans-Golgi acidification in cystic fibrosis
-
Seksek, O., Biwersi, J. & Verkman, A. S. Evidence against defective trans-Golgi acidification in cystic fibrosis. J. Biol. Chem. 271, 15542-15548 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15542-15548
-
-
Seksek, O.1
Biwersi, J.2
Verkman, A.S.3
-
74
-
-
0034647915
-
Determinants of the pH of the Golgi complex
-
Schapiro, F. B. & Grinstein, S. Determinants of the pH of the Golgi complex. J. Biol. Chem. 275, 21025-21032 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 21025-21032
-
-
Schapiro, F.B.1
Grinstein, S.2
-
75
-
-
0035907355
-
+ exchanger localized to the trans-Golgi network
-
+ exchanger localized to the trans-Golgi network. J. Biol. Chem. 276, 17387-17394 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 17387-17394
-
-
Numata, M.1
Orlowski, J.2
-
76
-
-
0027399690
-
Functional activation of plasma membrane anion exchangers occurs in a pre-Golgi compartment
-
Ruetz, S., Lindsey, A. E., Ward, C. L. & Kopito, R. R. Functional activation of plasma membrane anion exchangers occurs in a pre-Golgi compartment. J. Cell Biol. 121, 37-48 (1993).
-
(1993)
J. Cell Biol.
, vol.121
, pp. 37-48
-
-
Ruetz, S.1
Lindsey, A.E.2
Ward, C.L.3
Kopito, R.R.4
-
77
-
-
0038239926
-
2+ pumps revealed by analysis of null mutants
-
2+ pumps revealed by analysis of null mutants. Ann. N. Y. Acad. Sci. 986, 453-460 (2003).
-
(2003)
Ann. N. Y. Acad. Sci.
, vol.986
, pp. 453-460
-
-
Shull, G.E.1
-
78
-
-
0035980029
-
Mechanisms of pH regulation in the regulated secretory pathway
-
Wu, M. M. et al. Mechanisms of pH regulation in the regulated secretory pathway. J. Biol. Chem. 276, 33027-33035 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33027-33035
-
-
Wu, M.M.1
-
79
-
-
0038105847
-
Organelle acidification and disease
-
Weisz, O. A. Organelle acidification and disease. Traffic 4, 57-64 (2003).
-
(2003)
Traffic
, vol.4
, pp. 57-64
-
-
Weisz, O.A.1
-
80
-
-
39849092445
-
CLC chloride channels and transporters: From genes to protein structure, pathology and physiology
-
Jentsch, T. J. CLC chloride channels and transporters: from genes to protein structure, pathology and physiology. Crit. Rev. Biochem. Mol. Biol. 43, 3-36 (2008).
-
(2008)
Crit. Rev. Biochem. Mol. Biol.
, vol.43
, pp. 3-36
-
-
Jentsch, T.J.1
-
81
-
-
33748146503
-
CFTR regulates phagosome acidification in macrophages and alters bactericidal activity
-
Di, A. et al. CFTR regulates phagosome acidification in macrophages and alters bactericidal activity. Nature Cell Biol. 8, 933-944 (2006).
-
(2006)
Nature Cell Biol.
, vol.8
, pp. 933-944
-
-
Di, A.1
-
82
-
-
1642483415
-
Mitochondrial pH monitored by a new engineered green fluorescent protein mutant
-
Abad, M. F., Di Benedetto, G., Magalhaes, P. J., Filippin, L. & Pozzan, T. Mitochondrial pH monitored by a new engineered green fluorescent protein mutant. J. Biol. Chem. 279, 11521-11529 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 11521-11529
-
-
Abad, M.F.1
Di Benedetto, G.2
Magalhaes, P.J.3
Filippin, L.4
Pozzan, T.5
-
83
-
-
0032499784
-
Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins
-
Llopis, J., McCaffery, J. M., Miyawaki, A., Farquhar, M. G. & Tsien, R. Y. Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins. Proc. Natl Acad. Sci. USA 95, 6803-6808 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 6803-6808
-
-
Llopis, J.1
McCaffery, J.M.2
Miyawaki, A.3
Farquhar, M.G.4
Tsien, R.Y.5
-
85
-
-
0018068221
-
The cycling of calcium, sodium, and protons across the inner membrane of cardiac mitochondria
-
Crompton, M. & Heid, I. The cycling of calcium, sodium, and protons across the inner membrane of cardiac mitochondria. Eur. J. Biochem. 91, 599-608 (1978).
-
(1978)
Eur. J. Biochem.
, vol.91
, pp. 599-608
-
-
Crompton, M.1
Heid, I.2
-
86
-
-
0028842554
-
Mitochondrial cation transport systems
-
Garlid, K. D., Sun, X., Paucek, P. & Woldegiorgis, G. Mitochondrial cation transport systems. Methods Enzymol. 260, 331-348 (1995).
-
(1995)
Methods Enzymol.
, vol.260
, pp. 331-348
-
-
Garlid, K.D.1
Sun, X.2
Paucek, P.3
Woldegiorgis, G.4
-
87
-
-
0028095807
-
Mitochondrial calcium transport: Physiological and pathological relevance
-
Gunter, T. E., Gunter, K. K., Sheu, S. S. & Gavin, C. E. Mitochondrial calcium transport: physiological and pathological relevance. Am. J. Physiol. 267, C313-C339 (1994).
-
(1994)
Am. J. Physiol.
, vol.267
-
-
Gunter, T.E.1
Gunter, K.K.2
Sheu, S.S.3
Gavin, C.E.4
-
88
-
-
0025319665
-
Role of calcium ions in regulation of mammalian intramitochondrial metabolism
-
McCormack, J. G., Halestrap, A. P. & Denton, R. M. Role of calcium ions in regulation of mammalian intramitochondrial metabolism. Physiol. Rev. 70, 391-425 (1990).
-
(1990)
Physiol. Rev.
, vol.70
, pp. 391-425
-
-
McCormack, J.G.1
Halestrap, A.P.2
Denton, R.M.3
-
89
-
-
0021116604
-
2+-induced diminution of the adenine nucleotide translocator
-
2+-induced diminution of the adenine nucleotide translocator. Biochim. Biophys. Acta 724, 278-285 (1983).
-
(1983)
Biochim. Biophys. Acta
, vol.724
, pp. 278-285
-
-
Moreno-Sanchez, R.1
-
91
-
-
0029143569
-
Decoding of cytosolic calcium oscillations in the mitochondria
-
Hajnoczky, G., Robb-Gaspers, L. D., Seitz, M. B. & Thomas, A. P. Decoding of cytosolic calcium oscillations in the mitochondria. Cell 82, 415-424 (1995).
-
(1995)
Cell
, vol.82
, pp. 415-424
-
-
Hajnoczky, G.1
Robb-Gaspers, L.D.2
Seitz, M.B.3
Thomas, A.P.4
-
92
-
-
0033776271
-
Changes in intramitochondrial and cytosolic pH: Early events that modulate caspase activation during apoptosis
-
Matsuyama, S., Llopis, J., Deveraux, Q. L., Tsien, R. Y. & Reed, J. C. Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis. Nature Cell Biol. 2, 318-325 (2000).
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 318-325
-
-
Matsuyama, S.1
Llopis, J.2
Deveraux, Q.L.3
Tsien, R.Y.4
Reed, J.C.5
-
93
-
-
0031993196
-
1-ATPase proton pump is required for function of the proapoptotic protein Bax in yeast and mammalian cells
-
1-ATPase proton pump is required for function of the proapoptotic protein Bax in yeast and mammalian cells. Mol. Cell 1, 327-336 (1998).
-
(1998)
Mol. Cell
, vol.1
, pp. 327-336
-
-
Matsuyama, S.1
Xu, Q.2
Velours, J.3
Reed, J.C.4
-
94
-
-
17644443845
-
Apoptosis and the laws of thermodynamics
-
Nicholls, D. et al. Apoptosis and the laws of thermodynamics. Nature Cell Biol. 2, E172-E173 (2000).
-
(2000)
Nature Cell Biol.
, vol.2
-
-
Nicholls, D.1
-
95
-
-
0033119834
-
Interdependent regulation of intracellular acidification and SHP-1 in apoptosis
-
Thangaraju, M., Sharma, K., Liu, D., Shen, S. H. & Srikant, C. B. Interdependent regulation of intracellular acidification and SHP-1 in apoptosis. Cancer Res. 59, 1649-1654 (1999). (Pubitemid 29160139)
-
(1999)
Cancer Research
, vol.59
, Issue.7
, pp. 1649-1654
-
-
Thangaraju, M.1
Sharma, K.2
Liu, D.3
Shen, S.-H.4
Srikant, C.B.5
-
96
-
-
60549094972
-
+ exchanger activity by parvovirus B19 protein NS1
-
+ exchanger activity by parvovirus B19 protein NS1. Cell Physiol. Biochem. 23, 211-220 (2009).
-
(2009)
Cell Physiol. Biochem.
, vol.23
, pp. 211-220
-
-
Lupescu, A.1
-
97
-
-
3543049961
-
+-exchanger leads to caspase-independent death of cerebellar granule neurons resembling paraptosis
-
+-exchanger leads to caspase-independent death of cerebellar granule neurons resembling paraptosis. Cell Death Differ. 11, 760-770 (2004).
-
(2004)
Cell Death Differ.
, vol.11
, pp. 760-770
-
-
Schneider, D.1
-
98
-
-
22144465170
-
Contribution of the endoplasmic reticulum to peroxisome formation
-
Hoepfner, D., Schildknegt, D., Braakman, I., Philippsen, P. & Tabak, H. F. Contribution of the endoplasmic reticulum to peroxisome formation. Cell 122, 85-95 (2005).
-
(2005)
Cell
, vol.122
, pp. 85-95
-
-
Hoepfner, D.1
Schildknegt, D.2
Braakman, I.3
Philippsen, P.4
Tabak, H.F.5
-
99
-
-
58049170675
-
Spatiotemporal dynamics of the ER-derived peroxisomal endomembrane system
-
Titorenko, V. I. & Rachubinski, R. A. Spatiotemporal dynamics of the ER-derived peroxisomal endomembrane system. Int. Rev. Cell. Mol. Biol. 272, 191-244 (2009).
-
(2009)
Int. Rev. Cell. Mol. Biol.
, vol.272
, pp. 191-244
-
-
Titorenko, V.I.1
Rachubinski, R.A.2
-
101
-
-
0033792138
-
Peroxisomes in human fibroblasts have a basic pH
-
Dansen, T. B., Wirtz, K. W., Wanders, R. J. & Pap, E. H. Peroxisomes in human fibroblasts have a basic pH. Nature Cell Biol. 2, 51-53 (2000).
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 51-53
-
-
Dansen, T.B.1
Wirtz, K.W.2
Wanders, R.J.3
Pap, E.H.4
-
102
-
-
0035966061
-
In Situ Measurements of the pH of Mammalian Peroxisomes Using the Fluorescent Protein pHluorin
-
DOI 10.1074/jbc.M109003200
-
Jankowski, A. et al. In situ measurements of the pH of mammalian peroxisomes using the fluorescent protein pHluorin. J. Biol. Chem. 276, 48748-48753 (2001). (Pubitemid 33653842)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.52
, pp. 48748-48753
-
-
Jankowski, A.1
Kim, J.H.2
Collins, R.F.3
Daneman, R.4
Walton, P.5
Grinstein, S.6
-
103
-
-
47249146893
-
Calcium dynamics in the peroxisomal lumen of living cells
-
Drago, I., Giacomello, M., Pizzo, P. & Pozzan, T. Calcium dynamics in the peroxisomal lumen of living cells. J. Biol. Chem. 283, 14384-14390 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 14384-14390
-
-
Drago, I.1
Giacomello, M.2
Pizzo, P.3
Pozzan, T.4
-
104
-
-
33847240145
-
Intracellular pH sensors: Design principles and functional significance
-
Srivastava, J., Barber, D. L. & Jacobson, M. P. Intracellular pH sensors: design principles and functional significance. Physiology (Bethesda) 22, 30-39 (2007).
-
(2007)
Physiology (Bethesda)
, vol.22
, pp. 30-39
-
-
Srivastava, J.1
Barber, D.L.2
Jacobson, M.P.3
-
105
-
-
0022179004
-
Cytoplasmic pH, a key determinant of growth factor-induced DNA synthesis in quiescent fibroblasts
-
Pouysségur, J., Franchi, A., L'Allemain, G. & Paris, S. Cytoplasmic pH, a key determinant of growth factor-induced DNA synthesis in quiescent fibroblasts. FEBS Lett. 190, 115-119 (1985).
-
(1985)
FEBS Lett.
, vol.190
, pp. 115-119
-
-
Pouysségur, J.1
Franchi, A.2
L'Allemain, G.3
Paris, S.4
-
107
-
-
0023762959
-
Bicarbonate determines cytoplasmic pH and suppresses mitogen-induced alkalinization in fibroblastic cells
-
Bierman, A., Cragoe, E. J., Jr, de Laat, S. W. & Moolenaar, W. H. Bicarbonate determines cytoplasmic pH and suppresses mitogen-induced alkalinization in fibroblastic cells. J. Biol. Chem. 263, 15253-15256 (1988).
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 15253-15256
-
-
Bierman, A.1
Cragoe, E.J.2
Jr De Laat, S.W.3
Moolenaar, W.H.4
-
110
-
-
0033119723
-
A novel role for carbonic anhydrase: Cytoplasmic pH gradient dissipation in mouse small intestinal enterocytes
-
Stewart, A. K., Boyd, C. A. & Vaughan-Jones, R. D. A novel role for carbonic anhydrase: cytoplasmic pH gradient dissipation in mouse small intestinal enterocytes. J. Physiol. 516, 209-217 (1999).
-
(1999)
J. Physiol.
, vol.516
, pp. 209-217
-
-
Stewart, A.K.1
Boyd, C.A.2
Vaughan-Jones, R.D.3
-
111
-
-
34548346862
-
PH nanoenvironment at the surface of single melanoma cells
-
Stock, C. et al. pH nanoenvironment at the surface of single melanoma cells. Cell Physiol. Biochem. 20, 679-686 (2007).
-
(2007)
Cell Physiol. Biochem.
, vol.20
, pp. 679-686
-
-
Stock, C.1
-
112
-
-
68149105927
-
Protons make tumor cells move like clockwork
-
Stock, C. & Schwab, A. Protons make tumor cells move like clockwork. Pflugers Arch. 458, 981-992 (2009).
-
(2009)
Pflugers Arch.
, vol.458
, pp. 981-992
-
-
Stock, C.1
Schwab, A.2
-
113
-
-
61849116777
-
Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization
-
Simons, M. et al. Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization. Nature Cell Biol. 11, 286-294 (2009).
-
(2009)
Nature Cell Biol.
, vol.11
, pp. 286-294
-
-
Simons, M.1
-
114
-
-
37649008205
-
Protons act as a transmitter for muscle contraction in C. elegans
-
Beg, A. A., Ernstrom, G. G., Nix, P., Davis, M. W. & Jorgensen, E. M. Protons act as a transmitter for muscle contraction in C. elegans. Cell 132, 149-160 (2008)
-
(2008)
Cell
, vol.132
, pp. 149-160
-
-
Beg, A.A.1
Ernstrom, G.G.2
Nix, P.3
Davis, M.W.4
Jorgensen, E.M.5
-
116
-
-
0035924576
-
2+ current in mammalian cone photoreceptors
-
2+ current in mammalian cone photoreceptors. Neuron 32, 1107-1117 (2001).
-
(2001)
Neuron
, vol.32
, pp. 1107-1117
-
-
Devries, S.H.1
-
117
-
-
3442883664
-
Carbonic anhydrases: Current state of the art, therapeutic applications and future prospects
-
Pastorekova, S., Parkkila, S., Pastorek, J. & Supuran, C. T. Carbonic anhydrases: current state of the art, therapeutic applications and future prospects. J. Enzyme Inhib. Med. Chem. 19, 199-229 (2004).
-
(2004)
J. Enzyme Inhib. Med. Chem.
, vol.19
, pp. 199-229
-
-
Pastorekova, S.1
Parkkila, S.2
Pastorek, J.3
Supuran, C.T.4
-
118
-
-
40949088992
-
Regulation of pH in the mammalian central nervous system under normal and pathological conditions: Facts and hypotheses
-
Obara, M., Szeliga, M. & Albrecht, J. Regulation of pH in the mammalian central nervous system under normal and pathological conditions: facts and hypotheses. Neurochem. Int. 52, 905-919 (2008).
-
(2008)
Neurochem. Int.
, vol.52
, pp. 905-919
-
-
Obara, M.1
Szeliga, M.2
Albrecht, J.3
-
119
-
-
59249092490
-
Intracellular pH regulation in heart
-
Vaughan-Jones, R. D., Spitzer, K. W. & Swietach, P. Intracellular pH regulation in heart. J. Mol. Cell Cardiol. 46, 318-331 (2008).
-
(2008)
J. Mol. Cell Cardiol.
, vol.46
, pp. 318-331
-
-
Vaughan-Jones, R.D.1
Spitzer, K.W.2
Swietach, P.3
-
120
-
-
14844293074
-
Impaired acidification in early endosomes of ClC-5 deficient proximal tubule
-
Hara-Chikuma, M., Wang, Y., Guggino, S. E., Guggino, W. B. & Verkman, A. S. Impaired acidification in early endosomes of ClC-5 deficient proximal tubule. Biochem. Biophys. Res. Commun. 329, 941-946 (2005).
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.329
, pp. 941-946
-
-
Hara-Chikuma, M.1
Wang, Y.2
Guggino, S.E.3
Guggino, W.B.4
Verkman, A.S.5
-
122
-
-
0035951282
-
Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man
-
Kornak, U. et al. Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man. Cell 104, 205-215 (2001).
-
(2001)
Cell
, vol.104
, pp. 205-215
-
-
Kornak, U.1
-
123
-
-
20144387287
-
Loss of the chloride channel ClC-7 leads to lysosomal storage disease and neurodegeneration
-
Kasper, D. et al. Loss of the chloride channel ClC-7 leads to lysosomal storage disease and neurodegeneration. EMBO J. 24, 1079-1091 (2005).
-
(2005)
EMBO J.
, vol.24
, pp. 1079-1091
-
-
Kasper, D.1
-
124
-
-
33748779034
-
Lysosomal storage disease upon disruption of the neuronal chloride transport protein ClC-6
-
Poet, M. et al. Lysosomal storage disease upon disruption of the neuronal chloride transport protein ClC-6. Proc. Natl Acad. Sci. USA 103, 13854-13859 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 13854-13859
-
-
Poet, M.1
-
125
-
-
37549056201
-
+-ATPase subunit ATP6V0A2
-
+-ATPase subunit ATP6V0A2. Nature Genet. 40, 32-34 (2008).
-
(2008)
Nature Genet.
, vol.40
, pp. 32-34
-
-
Kornak, U.1
|