-
1
-
-
3843097202
-
Classification of orally administered drugs on the World Health Organization Model List of Essential Medicines according to the biopharmaceutics classification system
-
Lindenberg M, Kopp S, Dressman JB. Classification of orally administered drugs on the World Health Organization Model List of Essential Medicines according to the biopharmaceutics classification system. Eur J Pharm Biopharm 2004;58:265-78.
-
(2004)
Eur J Pharm Biopharm
, vol.58
, pp. 265-278
-
-
Lindenberg, M.1
Kopp, S.2
Dressman, J.B.3
-
2
-
-
0037902222
-
Hypersensitivity reactions to chemotherapeutic drugs
-
Shepherd GM. Hypersensitivity reactions to chemotherapeutic drugs. Clin Rev Allergy Immunol 2003;24:253-62.
-
(2003)
Clin Rev Allergy Immunol
, vol.24
, pp. 253-262
-
-
Shepherd, G.M.1
-
3
-
-
0041703019
-
Pharmacological effects of formulation vehicles: Implications for cancer chemotherapy
-
ten Tije AJ, Verweij J, Loos WJ, Sparreboom A. Pharmacological effects of formulation vehicles: implications for cancer chemotherapy. Clin Pharmacokinet 2003;42:665-85.
-
(2003)
Clin Pharmacokinet
, vol.42
, pp. 665-685
-
-
ten Tije, A.J.1
Verweij, J.2
Loos, W.J.3
Sparreboom, A.4
-
4
-
-
39649092973
-
Nanotechnology and cancer
-
Heath JR, Davis ME. Nanotechnology and cancer. Annu Rev Med 2008;59:251-65.
-
(2008)
Annu Rev Med
, vol.59
, pp. 251-265
-
-
Heath, J.R.1
Davis, M.E.2
-
5
-
-
0035868768
-
Phase ii comparator study of oral versus intravenous topotecan in patients with chemosensitive small-cell lung cancer
-
von Pawel J, Gatzemeier U, Pujol JL, et al. Phase ii comparator study of oral versus intravenous topotecan in patients with chemosensitive small-cell lung cancer. J Clin Oncol 2001;19:1743-9.
-
(2001)
J Clin Oncol
, vol.19
, pp. 1743-1749
-
-
von Pawel, J.1
Gatzemeier, U.2
Pujol, J.L.3
-
6
-
-
0036159485
-
Patient preference and pharmacokinetics of oral modulated UFT versus intravenous fluorouracil and leucovorin: A randomised crossover trial in advanced colorectal cancer
-
Borner MM, Schoffski P, de Wit R, et al. Patient preference and pharmacokinetics of oral modulated UFT versus intravenous fluorouracil and leucovorin: a randomised crossover trial in advanced colorectal cancer. Eur J Cancer 2002;38:349-58.
-
(2002)
Eur J Cancer
, vol.38
, pp. 349-358
-
-
Borner, M.M.1
Schoffski, P.2
de Wit, R.3
-
7
-
-
38849106122
-
Effective oral chemotherapy for breast cancer: Pillars of strength
-
Findlay M, von Minckwitz G, Wardley A. Effective oral chemotherapy for breast cancer: pillars of strength. Ann Oncol 2008;19:212-22.
-
(2008)
Ann Oncol
, vol.19
, pp. 212-222
-
-
Findlay, M.1
von Minckwitz, G.2
Wardley, A.3
-
8
-
-
33745555767
-
The clinical and economic benefits of capecitabine and tegafur with uracil in metastatic colorectal cancer
-
Ward SE, Kaltenthaler E, Cowan J, Marples M, Orr B, Seymour MT. The clinical and economic benefits of capecitabine and tegafur with uracil in metastatic colorectal cancer. Br J Cancer 2006;95:27-34.
-
(2006)
Br J Cancer
, vol.95
, pp. 27-34
-
-
Ward, S.E.1
Kaltenthaler, E.2
Cowan, J.3
Marples, M.4
Orr, B.5
Seymour, M.T.6
-
9
-
-
33750072949
-
mTOR and cancer therapy
-
Easton JB, Houghton PJ. mTOR and cancer therapy. Oncogene 2006;25:6436-46.
-
(2006)
Oncogene
, vol.25
, pp. 6436-6446
-
-
Easton, J.B.1
Houghton, P.J.2
-
10
-
-
33750044299
-
When translation meets transformation: The mTOR story
-
Averous J, Proud CG. When translation meets transformation: the mTOR story. Oncogene 2006;25:6423-35.
-
(2006)
Oncogene
, vol.25
, pp. 6423-6435
-
-
Averous, J.1
Proud, C.G.2
-
11
-
-
43749116022
-
Antiproliferative effects of rapamycin as a single agent and in combination with carboplatin and paclitaxel in head and neck cancer cell lines
-
Aissat N, Le Tourneau C, Ghoul A, et al. Antiproliferative effects of rapamycin as a single agent and in combination with carboplatin and paclitaxel in head and neck cancer cell lines. Cancer Chemother Pharmacol 2008;62:305-13.
-
(2008)
Cancer Chemother Pharmacol
, vol.62
, pp. 305-313
-
-
Aissat, N.1
Le Tourneau, C.2
Ghoul, A.3
-
12
-
-
34347246648
-
Drugging the bad "AKT-TOR" to overcome TKI-resistant lung cancer
-
Settleman J, Kurie JM. Drugging the bad "AKT-TOR" to overcome TKI-resistant lung cancer. Cancer Cell 2007;12:6-8.
-
(2007)
Cancer Cell
, vol.12
, pp. 6-8
-
-
Settleman, J.1
Kurie, J.M.2
-
14
-
-
33748088524
-
An in vivo platform for translational drug development in pancreatic cancer
-
Rubio-Viqueira B, Jimeno A, Cusatis G, et al. An in vivo platform for translational drug development in pancreatic cancer. Clin Cancer Res 2006;12:4652-61.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4652-4661
-
-
Rubio-Viqueira, B.1
Jimeno, A.2
Cusatis, G.3
-
15
-
-
33847396528
-
Optimizing the development of targeted agents in pancreatic cancer: Tumor fine-needle aspiration biopsy as a platform for novel prospective ex vivo drug sensitivity assays
-
Rubio-Viqueira B, Mezzadra H, Nielsen ME, et al. Optimizing the development of targeted agents in pancreatic cancer: tumor fine-needle aspiration biopsy as a platform for novel prospective ex vivo drug sensitivity assays. Mol Cancer Ther 2007;6:515-23.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 515-523
-
-
Rubio-Viqueira, B.1
Mezzadra, H.2
Nielsen, M.E.3
-
16
-
-
34548636132
-
Elucidation of a universal size-control mechanism in Drosophila and mammals
-
Dong J, Feldmann G, Huang J, et al. Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 2007;130:1120-33.
-
(2007)
Cell
, vol.130
, pp. 1120-1133
-
-
Dong, J.1
Feldmann, G.2
Huang, J.3
-
17
-
-
33645782798
-
Evaluation of an immunoassay of whole blood sirolimus in pediatric transplant patients in comparison with high-performance liquid chromatography/tandem mass spectrometry
-
Vicente FB, Smith FA, Peng Y, Wang S. Evaluation of an immunoassay of whole blood sirolimus in pediatric transplant patients in comparison with high-performance liquid chromatography/tandem mass spectrometry. Clin Chem Lab Med 2006;44:497-9.
-
(2006)
Clin Chem Lab Med
, vol.44
, pp. 497-499
-
-
Vicente, F.B.1
Smith, F.A.2
Peng, Y.3
Wang, S.4
-
18
-
-
18144423488
-
A fast and simple high-performance liquid chromatography/mass spectrometry method for simultaneous measurement of whole blood tacrolimus and sirolimus
-
Wang S, Magill JE, Vicente FB. A fast and simple high-performance liquid chromatography/mass spectrometry method for simultaneous measurement of whole blood tacrolimus and sirolimus. Arch Pathol Lab Med 2005;129:661-5.
-
(2005)
Arch Pathol Lab Med
, vol.129
, pp. 661-665
-
-
Wang, S.1
Magill, J.E.2
Vicente, F.B.3
-
19
-
-
33947254016
-
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: A new paradigm for combination therapy in solid cancers
-
Feldmann G, Dhara S, Fendrich V, et al. Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers. Cancer Res 2007;67:2187-96.
-
(2007)
Cancer Res
, vol.67
, pp. 2187-2196
-
-
Feldmann, G.1
Dhara, S.2
Fendrich, V.3
-
20
-
-
0034722888
-
The rapamycin-sensitive signal transduction pathway as a target for cancer therapy
-
Hidalgo M, Rowinsky EK. The rapamycin-sensitive signal transduction pathway as a target for cancer therapy. Oncogene 2000;19:6680-6.
-
(2000)
Oncogene
, vol.19
, pp. 6680-6686
-
-
Hidalgo, M.1
Rowinsky, E.K.2
-
21
-
-
33745150462
-
Ribosomal protein S6 phosphorylation: From protein synthesis to cell size
-
Ruvinsky I, Meyuhas O. Ribosomal protein S6 phosphorylation: from protein synthesis to cell size. Trends Biochem Sci 2006;31:342-8.
-
(2006)
Trends Biochem Sci
, vol.31
, pp. 342-348
-
-
Ruvinsky, I.1
Meyuhas, O.2
-
22
-
-
0032580354
-
Drug delivery and targeting
-
Langer R. Drug delivery and targeting. Nature 1998;392:5-10.
-
(1998)
Nature
, vol.392
, pp. 5-10
-
-
Langer, R.1
-
23
-
-
34547515086
-
Nab-paclitaxel for breast cancer: A new formulation with an improved safety profile and greater efficacy
-
Henderson IC, Bhatia V. Nab-paclitaxel for breast cancer: a new formulation with an improved safety profile and greater efficacy. Expert review of anticancer therapy 2007;7:919-43.
-
(2007)
Expert review of anticancer therapy
, vol.7
, pp. 919-943
-
-
Henderson, I.C.1
Bhatia, V.2
-
24
-
-
33748498232
-
Pros and cons of the liposome platform in cancer drug targeting
-
Gabizon AA, Shmeeda H, Zalipsky S. Pros and cons of the liposome platform in cancer drug targeting. J Liposome Res 2006;16:175-83.
-
(2006)
J Liposome Res
, vol.16
, pp. 175-183
-
-
Gabizon, A.A.1
Shmeeda, H.2
Zalipsky, S.3
-
25
-
-
19944411434
-
Efficacy and safety of liposomal anthracyclines in phase I/II clinical trials
-
Alberts DS, Muggia FM, Carmichael J, et al. Efficacy and safety of liposomal anthracyclines in phase I/II clinical trials. Semin Oncol 2004;31:53-90.
-
(2004)
Semin Oncol
, vol.31
, pp. 53-90
-
-
Alberts, D.S.1
Muggia, F.M.2
Carmichael, J.3
-
26
-
-
37349080672
-
Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer
-
Kim DW, Kim SY, Kim HK, et al. Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer. Ann Oncol 2007;18:2009-14.
-
(2007)
Ann Oncol
, vol.18
, pp. 2009-2014
-
-
Kim, D.W.1
Kim, S.Y.2
Kim, H.K.3
-
27
-
-
42649145864
-
(amino acid) micelle nanocarriers in preclinical and clinical studies
-
Matsumura Y. Poly (amino acid) micelle nanocarriers in preclinical and clinical studies. Adv Drug Deliv Rev 2008;60:899-914.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 899-914
-
-
Poly, M.Y.1
-
28
-
-
27744553029
-
A phase I and pharmacokinetic study of paclitaxel poliglumex (XYOTAX), investigating both 3-weekly and 2-weekly schedules
-
Boddy AV, Plummer ER, Todd R, et al. A phase I and pharmacokinetic study of paclitaxel poliglumex (XYOTAX), investigating both 3-weekly and 2-weekly schedules. Clin Cancer Res 2005;11:7834-40.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7834-7840
-
-
Boddy, A.V.1
Plummer, E.R.2
Todd, R.3
-
29
-
-
34047131087
-
Functional polymeric nanoparticles: An efficient and promising tool for active delivery of bioactives
-
Nahar M, Dutta T, Murugesan S, et al. Functional polymeric nanoparticles: an efficient and promising tool for active delivery of bioactives. Crit Rev Ther Drug Carrier Systems 2006;23:259-318.
-
(2006)
Crit Rev Ther Drug Carrier Systems
, vol.23
, pp. 259-318
-
-
Nahar, M.1
Dutta, T.2
Murugesan, S.3
-
30
-
-
37249093948
-
Biodegradable, polymeric nanoparticle delivery systems for cancer therapy
-
Pridgen EM, Langer R, Farokhzad OC. Biodegradable, polymeric nanoparticle delivery systems for cancer therapy. Nanomed 2007;2:669-80.
-
(2007)
Nanomed
, vol.2
, pp. 669-680
-
-
Pridgen, E.M.1
Langer, R.2
Farokhzad, O.C.3
-
31
-
-
34248205135
-
Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): A novel strategy for human cancer therapy
-
Bisht S, Feldmann G, Soni S, et al. Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy. J Nanobiotechnol 2007;5:3.
-
(2007)
J Nanobiotechnol
, vol.5
, pp. 3
-
-
Bisht, S.1
Feldmann, G.2
Soni, S.3
-
32
-
-
39049124118
-
Nanoparticle strategies for the oral delivery of insulin
-
Damge C, Reis CP, Maincent P. Nanoparticle strategies for the oral delivery of insulin. Expert Opin Drug Deliv 2008;5:45-68.
-
(2008)
Expert Opin Drug Deliv
, vol.5
, pp. 45-68
-
-
Damge, C.1
Reis, C.P.2
Maincent, P.3
-
33
-
-
34248674637
-
Polymeric nano- and microparticle technologies for oral gene delivery
-
Bhavsar MD, Amiji MM. Polymeric nano- and microparticle technologies for oral gene delivery. Expert Opin Drug Deliv 2007;4:197-213.
-
(2007)
Expert Opin Drug Deliv
, vol.4
, pp. 197-213
-
-
Bhavsar, M.D.1
Amiji, M.M.2
-
34
-
-
23644437127
-
Bioadhesive properties of pegylated nanoparticles
-
Yoncheva K, Gomez S, Campanero MA, Gamazo C, Irache JM. Bioadhesive properties of pegylated nanoparticles. Expert Opin Drug Deliv 2005;2:205-18.
-
(2005)
Expert Opin Drug Deliv
, vol.2
, pp. 205-218
-
-
Yoncheva, K.1
Gomez, S.2
Campanero, M.A.3
Gamazo, C.4
Irache, J.M.5
-
35
-
-
36849029088
-
-
Ma WW, Jimeno A. Temsirolimus. Drugs Today (Barc) 2007;43:659-69.
-
Ma WW, Jimeno A. Temsirolimus. Drugs Today (Barc) 2007;43:659-69.
-
-
-
-
37
-
-
33748194240
-
Recent developments in targeting the mammalian target of rapamycin (mTOR) kinase pathway
-
Smolewski P. Recent developments in targeting the mammalian target of rapamycin (mTOR) kinase pathway. Anticancer Drugs 2006;17:487-94.
-
(2006)
Anticancer Drugs
, vol.17
, pp. 487-494
-
-
Smolewski, P.1
-
38
-
-
38649140450
-
Phase I trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573; MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with advanced malignancies
-
Mita MM, Mita AC, Chu QS, et al. Phase I trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573; MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with advanced malignancies. J Clin Oncol 2008;26:361-7.
-
(2008)
J Clin Oncol
, vol.26
, pp. 361-367
-
-
Mita, M.M.1
Mita, A.C.2
Chu, Q.S.3
-
39
-
-
4544275025
-
Challenges and solutions for the delivery of biotech drugs - a review of drug nanocrystal technology and lipid nanoparticles
-
Muller RH, Keck CM. Challenges and solutions for the delivery of biotech drugs - a review of drug nanocrystal technology and lipid nanoparticles. J Biotechnol 2004;113:151-70.
-
(2004)
J Biotechnol
, vol.113
, pp. 151-170
-
-
Muller, R.H.1
Keck, C.M.2
-
41
-
-
42649132499
-
Protein nanoparticles as drug carriers in clinical medicine
-
Hawkins MJ, Soon-Shiong P, Desai N. Protein nanoparticles as drug carriers in clinical medicine. Adv Drug Deliv Rev 2008;60:876-85.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 876-885
-
-
Hawkins, M.J.1
Soon-Shiong, P.2
Desai, N.3
-
43
-
-
34547653668
-
Enhanced permeability and retention of macromolecular drugs in solid tumors: A royal gate for targeted anticancer nanomedicines
-
Greish K. Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines. J Drug Target 2007;15:457-64.
-
(2007)
J Drug Target
, vol.15
, pp. 457-464
-
-
Greish, K.1
-
44
-
-
34548831938
-
Bacterially-derived nanocells for tumor-targeted delivery of chemotherapeutics and cell cycle inhibitors
-
MacDiarmid JA, Madrid-Weiss J, Amaro-Mugridge NB, Phillips L, Brahmbhatt H. Bacterially-derived nanocells for tumor-targeted delivery of chemotherapeutics and cell cycle inhibitors. Cell Cycle Georgetown TX 2007;6:2099-105.
-
(2007)
Cell Cycle Georgetown TX
, vol.6
, pp. 2099-2105
-
-
MacDiarmid, J.A.1
Madrid-Weiss, J.2
Amaro-Mugridge, N.B.3
Phillips, L.4
Brahmbhatt, H.5
-
45
-
-
34247620285
-
Bacterially derived 400 nm particles for encapsulation and cancer cell targeting of chemotherapeutics
-
MacDiarmid JA, Mugridge NB, Weiss JC, et al. Bacterially derived 400 nm particles for encapsulation and cancer cell targeting of chemotherapeutics. Cancer Cell 2007;11:431-45.
-
(2007)
Cancer Cell
, vol.11
, pp. 431-445
-
-
MacDiarmid, J.A.1
Mugridge, N.B.2
Weiss, J.C.3
-
47
-
-
34250780578
-
Radiolabeled anti-claudin 4 and anti-prostate stem cell antigen: Initial imaging in experimental models of pancreatic cancer
-
Foss CA, Fox JJ, Feldmann G, et al. Radiolabeled anti-claudin 4 and anti-prostate stem cell antigen: initial imaging in experimental models of pancreatic cancer. Mol Imaging 2007;6:131-9.
-
(2007)
Mol Imaging
, vol.6
, pp. 131-139
-
-
Foss, C.A.1
Fox, J.J.2
Feldmann, G.3
-
48
-
-
34547367172
-
Imaging pancreatic cancer using surface-functionalized quantum dots
-
Qian J, Yong KT, Roy I, et al. Imaging pancreatic cancer using surface-functionalized quantum dots. J Phys Chem 2007;111:6969-72.
-
(2007)
J Phys Chem
, vol.111
, pp. 6969-6972
-
-
Qian, J.1
Yong, K.T.2
Roy, I.3
|