Wheat germ agglutinin binds to the epidermal growth factor receptor of artificial Caco-2 membranes as detected by silver nanoparticle enhanced fluorescence

Pharmaceutical Research

Volumn 20, Issue 5, 2003, Pages 833-839

  Lochner, Nina ^a   Pittner, Fritz ^a   Wirth, Michael ^a   Gabor, Franz ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

Caco 2; EGF; Lectin mediated drug delivery; Silver nanoparticle enhanced fluorescence; Wheat germ agglutinin

Indexed keywords

CARBOHYDRATE; EPIDERMAL GROWTH FACTOR RECEPTOR; LEPTIN; LIGAND; NANOPARTICLE; SILVER; WHEAT GERM AGGLUTININ;

ARTICLE; CANCER CELL CULTURE; CELL MEMBRANE; CELL STRAIN CACO 2; DRUG DELIVERY SYSTEM; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MEMBRANE VESICLE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RECEPTOR BINDING;

BINDING SITES; CACO-2 CELLS; FLUORESCENCE; HUMANS; MEMBRANES, ARTIFICIAL; NANOTECHNOLOGY; RECEPTOR, EPIDERMAL GROWTH FACTOR; SILVER; WHEAT GERM AGGLUTININS;

EID: 0242584996     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1023406224028     Document Type: Article

References (28)

1. U. B. Kompella and V. H. L. Lee. Delivery systems for penetration enhancement of peptide and protein drugs: design considerations. Adv Drug Deliv. Rev. 8:115-162 (1992).
2. F. Gabor, M. Wirth, B. Jurkovich, G. Theyer, G. Walcher, and G. Hamilton. Lectin-mediated bioadhesion: proteolytic stability and binding-characteristics of wheat germ agglutinin and solanum tuberosum lectin on Caco-2, HT-29 and human colonocytes. J Control. Release 49:27-37 (1997).
3. P. G. Brady, A.M. Vannier and J. G. Banwell. Identification of the dietary lectin, wheat germ agglutinin, in human intestinal contents. Gastroenterology 75:236-239 (1978).
4. B. Ertl, F. Heigl, M. Wirth and F. Gabor. Lectin-mediated bioadhesion: Preparation, stability and Caco-2 binding of wheat germ agglutinin-functionalized poly(D,L-lactic-co-glycolic acid)-microspheres, J Drug Target. 8:173-184 (2000).
5. R. D. Vale and E. M. Shooter. Epidermal growth factor on PC 12 cells: alteration of binding properties by lectins. J. Cell. Biochem. 22:99-109 (1983).
6. F. Y. Zeng, A. Benguria, S. Kafert, S. Andre, H. J. Gabius, and A. Villalobo. Differential response of the epidermal growth factor receptor tyrosine kinase activity to several plant and mammalian lectins. Mol. Cell. Biochem. 142:117-124 (1995).
7. Ch. Lobmaier, G. Hawa, M Götzinger, M. Wirth, F. Pittner, and F. Gabor. Direct monitoring of molecular recognition processes using fluorescence enhancement at colloid coated microplates. J. Mol. Recognit. 14:215-222 (2000).
8. J. R. Lakowicz, Y. Shen, S. D'Auria, J. Malicka, J. Fang, Z. Gryczynski, and I. Grzyczynski. Radiative decay engineering. Anal. Biochem. 301:261-277 (2002).
9. J. R. Lakowicz. Radiative decay engineering: biophysical and biomedical applications. Anal. Biochem. 298:1-24 (2001).
10. F. J. Field, E. Born, S. Murthy, and S. N. Mathur. Caveolin is present in intestinal cells: role in cholesterol trafficking? J. Lipid Res. 39:1938-1950 (1997).
11. 2+-transport in plasma membrane vesicles of renal epithelium of the Mozambique tilapia (Oreochromis mossambicus). J. Exp. Biol. 200:1931-1939 (1997).
12. N. M. Rao, A. L. Plant, V. Silin, S. Wight, and S. W. Hui. Characterization of biomimetic surfaces formed from cell membranes. Biophys. J. 73:3066-3077 (1997).
13. E. Kalb, S. Frey, and L. Tamm. Formation of supported planar bilayers by fusion of vesicles to supported phospholipid monolayers. Biochem. Biophys. Acta 1103:307-316 (1992).
14. G. Carpenter and S. Cohen. Epidermal growth factor. J. Biol. Chem. 265:7709-7712 (1990).
15. I. J. Hidalgo, A. Kato, and R. T. Borchardt. Binding of epidermal growth factor by human colon carcinoma cell (Caco-2) monolayers. Biochem. Biophys. Res. Commun. 160:317-324 (1989).
16. A. Rizzino, E. Ruff, and P. Kazakoff. Isolation and characterization of A-431 cells that retain high epidermal growth factor binding capacity and respond to epidermal growth factor by stimulation. Cancer Res. 48:2377-2381 (1988).
17. J. M. Moseley and L. J. Suva. Molecular characterization of the EGF receptor and involvement of glycosyl moieties in the binding of EGF to its receptor on a clonal osteosarcoma cell line. Calcif. Tissue Int. 38:109-114 (1986).
18. A. Ullrich, L. Coussens, J. S. Hayflick, T. J. Dull, A. Gray, A. W. Tam, J. Lee, Y. Yarden, T. A. Libermann, and J. Schlessinger. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 309:418-425 (1984).
19. C. Greenfield, I. Hiles, M. D. Waterfield, M. Federwisch, A. Wollmer, T. L. Blundell, and N. McDonald. Epidermal growth factor binding induces a conformational change in the external domain of its receptor. EMBO J. 8:4115-4123 (1989).
20. I. Lax, A. K. Mitra, C. Ravera, D. R. Hurwitz, M. Rubinstein, A. Ullrich, and R. M. Stroud, and J. Schlessinger. Epidermal growth factor induces oligomerization of soluble, extracellular, ligand-binding domain of EGF-receptor. A low resolution projection structure of the ligand-binding domain. J. Biol. Chem. 266:13828-13833 (1991).
21. I. Lax, W. H. Burgess, F. Bellot, A. Ullrich, J. Schlessinger, and D. Givol. Localization of a major receptor-binding domain for epidermal growth factor by affinity labeling. Mol. Cell. Biol. 8:1831-1834 (1988).
22. T. Tsuda, Y. Ikeda, and N. Taniguchi. The Asn-420-linked sugar chain in human epidermal growth factor receptor suppresses ligand-independent spontaneous oligomerization. J. Biol. Chem. 275:21988-21994 (2000).
23. C. J. M. Stroop, W. Weber, G. J. Gerwig, M. Nimtz, J. P. Kamerling, and F. G. Vliegenhart. Characterization of the carbohydrate chains of the secreted form of the human epidermal growth factor receptor. Glycobiol. 10:901-917 (2000).
24. H. Haigler, J. F. Ash, S. J. Singer, and S. Cohen. Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431. Proc. Natl. Acad. Sci. USA 75:3317-3321 (1978).
25. M. Wirth, G. Hamilton, and F. Gabor. Lectin-mediated drug targeting: Quantification of binding and internalisation of wheat germ agglutinin and solanum tuberosum lectin using Caco-2 and HT-29 cells. J. Drug Target. 6:95-104 (1998).
26. M. Wirth, C. Kneuer, C.M. Lehr, and F. Gabor. Lectin-mediated drug delivery: Discrimination between cytoadhesion and cytoinvasion and evidence for lysosomal accumulation of wheat germ agglutinin in the Caco-2 model. J Drug Target, 10:439-448 (2002).
27. M. Wirth, A. Fuchs, M. Wolf, B. Ertl, and F. Gabor. Lectin-mediated drug targeting: Preparation, binding characteristics and antiproliferative activity of wheat germ agglutinin conjugated doxorubicin on Caco-2 cells. Pharm. Res. 15:1031-1037 (1998).
28. G. Todderud and G. Carpenter. Epidermal growth factor: the receptor and its function. Biofactors 2:11-15 (1989).