Folic acid functionalized nanoparticles for enhanced oral drug delivery

Molecular Pharmaceutics

Volumn 9, Issue 7, 2012, Pages 2103-2110

  Roger, Emilie ^a   Kalscheuer, Stephen ^a   Kirtane, Ameya ^a   Guru, Bharath Raja ^a   Grill, Alex E ^a   Whittum Hudson, Judith ^b   Panyam, Jayanth ^a,c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Caco 2 cells; folic acid; oral bioavailability; polymeric systems; targeted delivery

Indexed keywords

6 COUMARIN; COUMARIN DERIVATIVE; DOCETAXEL; FOLATE RECEPTOR; FOLIC ACID; GLYCOPROTEIN P; NANOPARTICLE; PACLITAXEL; POLYGLACTIN; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN CACO 2; CELL TRANSPORT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG PENETRATION; DRUG SOLUBILITY; FLOW CYTOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNALIZATION; NANOENCAPSULATION; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY;

ABSORPTION; ADMINISTRATION, ORAL; BIOLOGICAL AVAILABILITY; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; EPITHELIAL CELLS; FOLIC ACID; HUMANS; INTESTINES; LACTIC ACID; NANOPARTICLES; P-GLYCOPROTEIN; PACLITAXEL; PERMEABILITY; POLYGLYCOLIC ACID; POLYMERS;

EID: 84863325067     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp2005388     Document Type: Article

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