Meta-analysis of anticancer drug structures - Significance of their polar allylic moieties

Anti-Cancer Agents in Medicinal Chemistry

Volumn 7, Issue 2, 2007, Pages 209-222

  Radin, Norman S ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b NONE   (United States)

Author keywords

Allylic anticancer drugs; Ceramide in cancer therapy; Reactive oxygen species; Sphingolipids as coenzymes; Thiol condensations; Ubiquinone interference

Indexed keywords

4 DEDIMETHYLAMINOSANCYCLINE; 7 ETHYL 10 HYDROXYCAMPTOTHECIN; ANTINEOPLASTIC AGENT; ARSENIC TRIOXIDE; CAMPTOTHECIN; CERAMIDE; CERAMIDE DERIVATIVE; CISPLATIN; COLCHICINE; COLECALCIFEROL; CURCUMIN; CYTARABINE; DACTINOMYCIN; DOCETAXEL; DOXORUBICIN; DOXYCYCLINE; EMODIN; ETOPOSIDE; FARNESOL; FENRETINIDE; MITOXANTRONE; PACLITAXEL; QUERCETIN; RAPAMYCIN; RETINOIC ACID; SPHINGOLIPID; SULFORAPHANE; TETRACYCLINE; UNINDEXED DRUG; VINCRISTINE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CANCER RESISTANCE; DRUG EFFICACY; DRUG METABOLISM; DRUG OXIDATION; DRUG POTENTIATION; DRUG RESPONSE; DRUG STRUCTURE; ENZYME ACTIVITY; HUMAN; LIPOGENESIS; LIPOPHILICITY; MICHAEL ADDITION; NONHUMAN; PROTEIN EXPRESSION; REVIEW; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CERAMIDES; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

ATOMS; CARBON; CELL DEATH; CELL PROLIFERATION; CERAMIDES; CONDENSATION; DISEASES; ESTERS; FINANCIAL MARKETS; KETONES; LIPIDS; MOLECULES; ORGANIC POLYMERS; OXYGEN;

ANTICANCER DRUG; CANCER THERAPY; REACTIVE OXYGEN SPECIES; SPHINGOLIPIDS; UBIQUINONE;

DRUG PRODUCTS;

EID: 84938065936     PISSN: 18715206     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152007780058696     Document Type: Review

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