Manumycin A and its analogues are irreversible inhibitors of neutral sphingomyelinase

ChemBioChem

Volumn 2, Issue 2, 2001, Pages 141-143

  Arenz, Christoph ^c   Thutewohl, Michael ^a   Block, Oliver ^b   Waldmann, Herbert ^a   Altenbach, Hans Josef ^b   Giannis, Athanassios ^c  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b UNIVERSITY OF WUPPERTAL   (Germany)

^c UNIVERSITY OF KARLSRUHE   (Germany)

Author keywords

Hydrolases; Inhibitors; Manumycins; Signal transduction; Sphingomyelinases

Indexed keywords

AMIDE; ENZYME INHIBITOR; MANUMYCIN; NONSTEROID ANTIINFLAMMATORY AGENT; P21(RAS) FARNESYL PROTEIN TRANSFERASE; P21(RAS) FARNESYL-PROTEIN TRANSFERASE; POLYENE; SPHINGOMYELIN PHOSPHODIESTERASE; TRANSFERASE;

ANIMAL; ARTICLE; BRAIN; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; MICROSOME; RAT; SIGNAL TRANSDUCTION; SYNTHESIS;

ALKYL AND ARYL TRANSFERASES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRAIN; ENZYME INHIBITORS; KINETICS; MICROSOMES; POLYENES; POLYUNSATURATED ALKAMIDES; RATS; SIGNAL TRANSDUCTION; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 0035793648     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/1439-7633(20010202)2:2<141::AID-CBIC141>3.0.CO;2-P     Document Type: Article

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