2-Aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors

Cancer Research

Volumn 62, Issue 11, 2002, Pages 3113-3119

  Beckers, Thomas ^a   Reissmann, Thomas ^a   Schmidt, Mathias ^a   Fiebig, Heinz H ^b   Burger, Angelika M ^b   Vanhoefer, Udo ^c   Mahboobi, Siavosh ^d   Pongratz, Herwig ^d   Hockemeyer, Jörg ^d   Frieser, Markus ^d   Hufsky, Harald ^d  

^a ASTA MEDICA AG   (Germany)

^b TUMOR BIOLOGY CENTER   (Germany)

^c UNIVERSITY OF ESSEN MEDICAL SCHOOL   (Germany)

^d UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHOXY 1H 2 INDOLYLPHENYLMETHANONE; ALPHA TUBULIN; BETA TUBULIN; COLCHICINE; D 64131; D 68144; ECDYSONE; GUANOSINE TRIPHOSPHATASE; INDOLE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN; PACLITAXEL; PROTEIN P21; PROTON PUMP; UNCLASSIFIED DRUG; VINCRISTINE;

AMELANOTIC MELANOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE; CELL PROLIFERATION; COLON CARCINOMA; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; MICROTUBULE ASSEMBLY; MOUSE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; G2 PHASE; GTP PHOSPHOHYDROLASES; HELA CELLS; HUMANS; INDOLES; MELANOMA, AMELANOTIC; MICE; MICE, NUDE; MITOSIS; P-GLYCOPROTEINS; TUBULIN; TUBULIN MODULATORS; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0036606778     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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