-
1
-
-
0008610545
-
Evidence for phosphatidic acid as the sodium carrier
-
1. HOKIN LE, HOKIN MR: Evidence for phosphatidic acid as the sodium carrier. Nature 184:1068-1069, 1959
-
(1959)
Nature
, vol.184
, pp. 1068-1069
-
-
Hokin, L.E.1
Hokin, M.R.2
-
2
-
-
0025877969
-
The structure and function of renal glycosphingolipids
-
2. SHAYMAN JA, RADIN NS: The structure and function of renal glycosphingolipids. Am J Physiol 260:F291-F302, 1991
-
(1991)
Am J Physiol
, vol.260
-
-
Shayman, J.A.1
Radin, N.S.2
-
3
-
-
0029927759
-
Sphingolipids: Their role in intracellular signaling and renal growth
-
3. SHAYMAN JA: Sphingolipids: Their role in intracellular signaling and renal growth. J Am Soc Nephrol 7:171-182, 1996
-
(1996)
J Am Soc Nephrol
, vol.7
, pp. 171-182
-
-
Shayman, J.A.1
-
4
-
-
0014868653
-
On the chemistry and occurrence of sphingolipid long-chain bases
-
4. KARLSSON KA: On the chemistry and occurrence of sphingolipid long-chain bases. Chem Phys Lipids 5:6-43, 1970
-
(1970)
Chem Phys Lipids
, vol.5
, pp. 6-43
-
-
Karlsson, K.A.1
-
6
-
-
0024373904
-
Synaptic vesicle ceramide kinase: A calcium-stimulated lipid kinase that co-purifies with brain synaptic vesicles
-
6. BAJJALIEH SM, MARTIN TFJ, FLOOR E: Synaptic vesicle ceramide kinase: A calcium-stimulated lipid kinase that co-purifies with brain synaptic vesicles. J Biol Chem 264:14917-14921, 1990
-
(1990)
J Biol Chem
, vol.264
, pp. 14917-14921
-
-
Bajjalieh, S.M.1
Martin, T.F.J.2
Floor, E.3
-
7
-
-
0029891058
-
A novel enzyme that catalyzes the esterification of N-acetylsphingosine
-
7. ABE A, SHAYMAN JA, RADIN NS: A novel enzyme that catalyzes the esterification of N-acetylsphingosine. J Biol Chem 271:14383-14389, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 14383-14389
-
-
Abe, A.1
Shayman, J.A.2
Radin, N.S.3
-
8
-
-
0031016228
-
Effect of sphingomyelin composition on the phase structure of phosphatidylcholine-sphingomyelin bilayers
-
8. BAR LK, BARENHOLZ Y, THOMPSON TE: Effect of sphingomyelin composition on the phase structure of phosphatidylcholine-sphingomyelin bilayers. Biochemistry 36:2507-2516, 1997
-
(1997)
Biochemistry
, vol.36
, pp. 2507-2516
-
-
Bar, L.K.1
Barenholz, Y.2
Thompson, T.E.3
-
10
-
-
0004231473
-
Physiology of membrane fluidity
-
edited by SHINITZKY M, Boca Raton, CRC Press
-
10. BARENHOLZ Y: Physiology of Membrane Fluidity, edited by SHINITZKY M, Sphingomyelin-lecithin balance in membranes: Composition, structure, and junction relationships, Boca Raton, CRC Press, 1984, pp 131-173
-
(1984)
Sphingomyelin-lecithin Balance in Membranes: Composition, Structure, and Junction Relationships
, pp. 131-173
-
-
Barenholz, Y.1
-
11
-
-
0021336360
-
Modulation of neuraminidase activity by the physical state of phospholipid bilayers containing gangliosides Gd1a and Gt1b
-
11. MYERS M, WORTMAN C, FREIRE E: Modulation of neuraminidase activity by the physical state of phospholipid bilayers containing gangliosides Gd1a and Gt1b. Biochemistry 23:1442-1448, 1984
-
(1984)
Biochemistry
, vol.23
, pp. 1442-1448
-
-
Myers, M.1
Wortman, C.2
Freire, E.3
-
12
-
-
0022573422
-
Thermotropic characterization of phosphatidylcholine vesicles containing ganglioside GM1 with homogeneous ceramide chain length
-
12. MASSERINI M, FREIRE E: Thermotropic characterization of phosphatidylcholine vesicles containing ganglioside GM1 with homogeneous ceramide chain length. Biochemistry 25:1043-1049, 1986
-
(1986)
Biochemistry
, vol.25
, pp. 1043-1049
-
-
Masserini, M.1
Freire, E.2
-
13
-
-
0024316313
-
Influence of glycolipid oligosaccharide and long-chain base composition on the thermotropic properties of dipalmitoylphosphatidylcholine large unilamellar vesicles containing gangliosides
-
13. MASSERINI M, PALESTINI P, FREIRE E: Influence of glycolipid oligosaccharide and long-chain base composition on the thermotropic properties of dipalmitoylphosphatidylcholine large unilamellar vesicles containing gangliosides. Biochemistry 28:5029-5032, 1989
-
(1989)
Biochemistry
, vol.28
, pp. 5029-5032
-
-
Masserini, M.1
Palestini, P.2
Freire, E.3
-
14
-
-
0028806694
-
A photo-reactive derivative of ganglioside GM1 specifically cross-links VIP21-caveolin on the cell surface
-
14. FRA A, MASSERINI M, PALESTINI P, SONNINO S, SIMONS K: A photo-reactive derivative of ganglioside GM1 specifically cross-links VIP21-caveolin on the cell surface. FEBS Lett 375:11-14, 1995
-
(1995)
FEBS Lett
, vol.375
, pp. 11-14
-
-
Fra, A.1
Masserini, M.2
Palestini, P.3
Sonnino, S.4
Simons, K.5
-
15
-
-
0032489443
-
Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane
-
15. OKAMOTO T, SCHLEGEL AM, SCHERER PE, LISANTI MP: Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane. J Biol Chem 273:5419-5422, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 5419-5422
-
-
Okamoto, T.1
Schlegel, A.M.2
Scherer, P.E.3
Lisanti, M.P.4
-
16
-
-
0032421354
-
Functions of lipid rafts in biological membranes
-
16. BROWN DA, LONDON E: Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol 14:111-136, 1998
-
(1998)
Annu Rev Cell Dev Biol
, vol.14
, pp. 111-136
-
-
Brown, D.A.1
London, E.2
-
17
-
-
0028820041
-
A detergent-free method for purifying caveolae membrane from tissue culture cells
-
17. SMART EJ, YING YS, MINEO C, ANDERSON RG: A detergent-free method for purifying caveolae membrane from tissue culture cells. Proc Natl Acad Sci USA 92:10104-10108, 1995
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 10104-10108
-
-
Smart, E.J.1
Ying, Y.S.2
Mineo, C.3
Anderson, R.G.4
-
18
-
-
0032509356
-
Separation of "glycosphingolipid signaling domain" from caveolin-containing membrane fraction in mouse melanoma B16 cells and its role in cell adhesion coupled with signaling
-
18. IWABUCHI K, HANDA K, HAKOMORI S: Separation of "glycosphingolipid signaling domain" from caveolin-containing membrane fraction in mouse melanoma B16 cells and its role in cell adhesion coupled with signaling. J Biol Chem 273:33766-33773, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 33766-33773
-
-
Iwabuchi, K.1
Handa, K.2
Hakomori, S.3
-
19
-
-
0030822255
-
Lipid microdomains in cell surface membranes
-
19. EDIDIN M: Lipid microdomains in cell surface membranes. Curr Opin Struct Biol 7:528-532, 1997
-
(1997)
Curr Opin Struct Biol
, vol.7
, pp. 528-532
-
-
Edidin, M.1
-
21
-
-
0003049750
-
The enzyme synthesis of sphingosine
-
21. BRADY RO, KOVAL GJ: The enzyme synthesis of sphingosine. J Biol Chem 233:26-31, 1958
-
(1958)
J Biol Chem
, vol.233
, pp. 26-31
-
-
Brady, R.O.1
Koval, G.J.2
-
22
-
-
0021333971
-
Enzymology of long-chain base synthesis by liver: Characterization of serine palmitoyltransferase in rat liver microsomes
-
22. WILLIAMS RD, WANG E, MERRILL AHJ: Enzymology of long-chain base synthesis by liver: Characterization of serine palmitoyltransferase in rat liver microsomes. Arch Biochem Biophys 228:282-291, 1984
-
(1984)
Arch Biochem Biophys
, vol.228
, pp. 282-291
-
-
Williams, R.D.1
Wang, E.2
Merrill, A.H.J.3
-
23
-
-
84942961893
-
Synthesis and degradation of spingosine bases in ansenula ciferrii
-
23. STOFFEL W, LE KIM D, STICHT G: Synthesis and degradation of spingosine bases in Ansenula ciferrii. Hoppe Seyler's Z Physiol Chem 349:1637-1644, 1968
-
(1968)
Hoppe Seyler's Z Physiol Chem
, vol.349
, pp. 1637-1644
-
-
Stoffel, W.1
Le Kim, D.2
Sticht, G.3
-
24
-
-
0014008349
-
Enzymatic synthesis of ceramide
-
24. SRIBNEY M: Enzymatic synthesis of ceramide. Biochim Biophys Acta 125:242-247, 1966
-
(1966)
Biochim Biophys Acta
, vol.125
, pp. 242-247
-
-
Sribney, M.1
-
25
-
-
0027074149
-
Biosynthesis of sphingolipids: Dihydroceramide and not sphinganine is desaturated by cultured cells
-
25. ROTHER J, VAN ECHTEN G, SCHWARZMANN G, SANDHOFF K: Biosynthesis of sphingolipids: Dihydroceramide and not sphinganine is desaturated by cultured cells. Biochem Biophys Res Commun 89:14-20, 1992
-
(1992)
Biochem Biophys Res Commun
, vol.89
, pp. 14-20
-
-
Rother, J.1
Van Echten, G.2
Schwarzmann, G.3
Sandhoff, K.4
-
26
-
-
0014027942
-
Enzymatic hydrolysis of sphingolipids. I. Hydrolysis and synthesis of ceramides by an enzyme from rat brain
-
26. GATT S: Enzymatic hydrolysis of sphingolipids. I. Hydrolysis and synthesis of ceramides by an enzyme from rat brain. J Biol Chem 241:3724-3730, 1966
-
(1966)
J Biol Chem
, vol.241
, pp. 3724-3730
-
-
Gatt, S.1
-
27
-
-
0030049758
-
Biosynthesis of N-acetylsphingosine by platelet-activating factor: Sphingosine CoA-independent transacetylase in HL-60 cells
-
27. LEE T, OU M, SHINOZAKI K, MALONE B, SNYDER F: Biosynthesis of N-acetylsphingosine by platelet-activating factor: Sphingosine CoA-independent transacetylase in HL-60 cells. J Biol Chem 271:209-217, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 209-217
-
-
Lee, T.1
Ou, M.2
Shinozaki, K.3
Malone, B.4
Snyder, F.5
-
28
-
-
0008586631
-
The enzymatic synthesis of sphingomyelin
-
28. SRIBNEY M, KENNEDY EP: The enzymatic synthesis of sphingomyelin. J Biol Chem 233:1315-1322, 1958
-
(1958)
J Biol Chem
, vol.233
, pp. 1315-1322
-
-
Sribney, M.1
Kennedy, E.P.2
-
29
-
-
0015987808
-
The enzymatic formation of sphingomyelin from ceramide and lecithin in mouse liver
-
29. ULLMAN MD, RADIN NS: The enzymatic formation of sphingomyelin from ceramide and lecithin in mouse liver. J Biol Chem 249:1506-1513, 1974
-
(1974)
J Biol Chem
, vol.249
, pp. 1506-1513
-
-
Ullman, M.D.1
Radin, N.S.2
-
30
-
-
0007712633
-
Sphingolipid metabolism in cultured fibroblasts: Microscopic and biochemical studies employing a fluorescent ceramide analogue
-
30. LIPSKY N, PAGANO RE: Sphingolipid metabolism in cultured fibroblasts: Microscopic and biochemical studies employing a fluorescent ceramide analogue. Proc Natl Acad Sci USA 80:2608-2612, 1983
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 2608-2612
-
-
Lipsky, N.1
Pagano, R.E.2
-
31
-
-
0021945533
-
The synthesis of sphingomyelin in the Morris hepatomas 7777 and 5123D is restricted to the plasma membrane
-
31. VAN DEN HILL A, VAN HEUSDEN GP, WIRTZ KWA: The synthesis of sphingomyelin in the Morris hepatomas 7777 and 5123D is restricted to the plasma membrane. Biochim Biophys Acta 833: 354-357, 1985
-
(1985)
Biochim Biophys Acta
, vol.833
, pp. 354-357
-
-
Van Den Hill, A.1
Van Heusden, G.P.2
Wirtz, K.W.A.3
-
32
-
-
0031034350
-
Relationships between phosphatidylcholine, phosphatidylethanolamine, and sphingomyelin metabolism in cultured oligodendrocytes
-
32. Vos JP, DEHAAS CGM, CAN GOLDE LM, LOPES-GARDOZO MJ: Relationships between phosphatidylcholine, phosphatidylethanolamine, and sphingomyelin metabolism in cultured oligodendrocytes. J Neurochem 68:1252-1260, 1997
-
(1997)
J Neurochem
, vol.68
, pp. 1252-1260
-
-
Vos, J.P.1
Dehaas, C.G.M.2
Can Golde, L.M.3
Lopes-Gardozo, M.J.4
-
33
-
-
0008613809
-
An alternative pathway for the enzymatic synthesis of sphingomyelin
-
33. BRADY RO, BRADLEY RM, YOUNG OM, KALLER HJ: An alternative pathway for the enzymatic synthesis of sphingomyelin. J Biol Chem 240:3693-3694, 1965
-
(1965)
J Biol Chem
, vol.240
, pp. 3693-3694
-
-
Brady, R.O.1
Bradley, R.M.2
Young, O.M.3
Kaller, H.J.4
-
34
-
-
0025351642
-
Intracellular calcium release mediated by sphingosine derivatives generated in cells
-
34. GHOSH TK, BIAN J, GILL DL: Intracellular calcium release mediated by sphingosine derivatives generated in cells. Science 248:1653-1656, 1990
-
(1990)
Science
, vol.248
, pp. 1653-1656
-
-
Ghosh, T.K.1
Bian, J.2
Gill, D.L.3
-
35
-
-
0028864621
-
A novel enzyme that cleaves the N-acyl linkage of ceramides in various glycosphingolipids as well as sphingomyelin to produce their lyso forms
-
35. ITO M, KURITA T, KITA K: A novel enzyme that cleaves the N-acyl linkage of ceramides in various glycosphingolipids as well as sphingomyelin to produce their lyso forms. J Biol Chem 270: 24370-24374, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 24370-24374
-
-
Ito, M.1
Kurita, T.2
Kita, K.3
-
36
-
-
0032716789
-
Glucosylceramide synthase: Assay and properties
-
36. SHAYMAN JA, ABE A: Glucosylceramide synthase: Assay and properties. Methods Enzymol 311:42-49, 1999
-
(1999)
Methods Enzymol
, vol.311
, pp. 42-49
-
-
Shayman, J.A.1
Abe, A.2
-
37
-
-
0022452207
-
Topology of glucosylceramide synthesis in Golgi membranes from porcine submaxillary glands
-
37. COSTE H, MARTEL MB, GOT R: Topology of glucosylceramide synthesis in Golgi membranes from porcine submaxillary glands. Biochim Biophys Acta 858:6-12, 1986
-
(1986)
Biochim Biophys Acta
, vol.858
, pp. 6-12
-
-
Coste, H.1
Martel, M.B.2
Got, R.3
-
38
-
-
0025168334
-
Ceramide 1-phosphate, a novel phospholipid in human leukemia (HL-60) cells: Synthesis via ceramide from sphingomyelin
-
38. DRESSLER KA, KOLESNICK RN: Ceramide 1-phosphate, a novel phospholipid in human leukemia (HL-60) cells: Synthesis via ceramide from sphingomyelin. J Biol Chem 265:14917-14921, 1990
-
(1990)
J Biol Chem
, vol.265
, pp. 14917-14921
-
-
Dressler, K.A.1
Kolesnick, R.N.2
-
39
-
-
0018451487
-
Diglyceride kinase from Escherichia coli: Purification in organic solvent and some properties of the enzyme
-
39. BOHNENBERGER E, SANDERMANN H JR: Diglyceride kinase from Escherichia coli: Purification in organic solvent and some properties of the enzyme. Eur J Biochem 94:401-407, 1979
-
(1979)
Eur J Biochem
, vol.94
, pp. 401-407
-
-
Bohnenberger, E.1
Sandermann H., Jr.2
-
40
-
-
0032509523
-
The formation of ceramide-1-phosphate during neutrophil phagocytosis and its role in liposome fusion
-
40. HINKOVSKA-GALCHEVA VT, BOXER LA, MANSFIELD PJ, HARSH D: The formation of ceramide-1-phosphate during neutrophil phagocytosis and its role in liposome fusion. J Biol Chem 273:33203-33209, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 33203-33209
-
-
Hinkovska-Galcheva, V.T.1
Boxer, L.A.2
Mansfield, P.J.3
Harsh, D.4
-
41
-
-
0032478741
-
Purification and characterization of 1-O-acylceramide synthase, a novel phospholipase A2
-
41. ABE A, SHAYMAN JA: Purification and characterization of 1-O-acylceramide synthase, a novel phospholipase A2. J Biol Chem 11:8467-8474, 1998
-
(1998)
J Biol Chem
, vol.11
, pp. 8467-8474
-
-
Abe, A.1
Shayman, J.A.2
-
43
-
-
0014866598
-
Studies on the biosynthesis and degradation of sphingosine bases
-
43. STOFFEL W: Studies on the biosynthesis and degradation of sphingosine bases. Chem Phys Lipids 5:139-158, 1970
-
(1970)
Chem Phys Lipids
, vol.5
, pp. 139-158
-
-
Stoffel, W.1
-
44
-
-
0029904257
-
Phosphatidate phosphohydrolase catalyzes the hydrolysis of ceramide 1-phosphate, lysophosphatidate, and sphingosine 1-phosphate
-
44. WAGGONER DW, GOMEZ-MUNOZ A, DEWALD J, BRINDLEY DN: Phosphatidate phosphohydrolase catalyzes the hydrolysis of ceramide 1-phosphate, lysophosphatidate, and sphingosine 1-phosphate. J Biol Chem 271:16506-16509, 1997
-
(1997)
J Biol Chem
, vol.271
, pp. 16506-16509
-
-
Waggoner, D.W.1
Gomez-Munoz, A.2
Dewald, J.3
Brindley, D.N.4
-
45
-
-
0024436946
-
Enzymatic synthesis of N,N-dimethylsphingosine: Demonstration of the sphingosine: N-methyltransferase in mouse brain
-
45. IGARASHI Y, HAKOMORI S: Enzymatic synthesis of N,N-dimethylsphingosine: Demonstration of the sphingosine: N-methyltransferase in mouse brain. Biochem Biophys Res Commun 164:1411-1416, 1989
-
(1989)
Biochem Biophys Res Commun
, vol.164
, pp. 1411-1416
-
-
Igarashi, Y.1
Hakomori, S.2
-
46
-
-
0026712872
-
Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase and sphinganine N-acyltransferase in mouse liver
-
46. MANDON EC, EHSES I, ROTHER J, VAN ECHTEN G, SANDHOFF K: Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase and sphinganine N-acyltransferase in mouse liver. J Biol Chem 267:11144-11148, 1992
-
(1992)
J Biol Chem
, vol.267
, pp. 11144-11148
-
-
Mandon, E.C.1
Ehses, I.2
Rother, J.3
Van Echten, G.4
Sandhoff, K.5
-
47
-
-
0014961287
-
Specificity in ceramide biosynthesis from long chain bases and various fatty acyl coenzyme As by brain microsomes
-
47. MORELL P, RADIN NS: Specificity in ceramide biosynthesis from long chain bases and various fatty acyl coenzyme As by brain microsomes. J Biol Chem 245:342-350, 1970
-
(1970)
J Biol Chem
, vol.245
, pp. 342-350
-
-
Morell, P.1
Radin, N.S.2
-
48
-
-
0028055154
-
Conversion of diacylglycerol to phosphatidylcholine on the basolateral surface of epithelial (Madin-Darby canine kidney) cells: Evidence for the reverse action of a sphingomyelin synthase
-
48. VAN HELVOORT A, VAN'T HOF W, RITSEMA T, SANDRA A, VAN MEER G: Conversion of diacylglycerol to phosphatidylcholine on the basolateral surface of epithelial (Madin-Darby canine kidney) cells: Evidence for the reverse action of a sphingomyelin synthase. J Biol Chem 269:1763-1769, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 1763-1769
-
-
Van Helvoort, A.1
Van't Hof, W.2
Ritsema, T.3
Sandra, A.4
Van Meer, G.5
-
49
-
-
0014027891
-
Enzymatic hydrolysis of sphingolipids. II. Hydrolysis of sphingomyelin by an enzyme from rat brain
-
49. BARNHOLZ Y, ROITMAN A, GATT S: Enzymatic hydrolysis of sphingolipids. II. Hydrolysis of sphingomyelin by an enzyme from rat brain. J Biol Chem 241:3731-3737, 1966
-
(1966)
J Biol Chem
, vol.241
, pp. 3731-3737
-
-
Barnholz, Y.1
Roitman, A.2
Gatt, S.3
-
51
-
-
0017183372
-
Sphingomyelinase activity at pH 7.4 in human brain and a comparison to activity at pH 5.0
-
51. RAO BG, SPENCE MW: Sphingomyelinase activity at pH 7.4 in human brain and a comparison to activity at pH 5.0. J Lipid Res 17:506-515, 1976
-
(1976)
J Lipid Res
, vol.17
, pp. 506-515
-
-
Rao, B.G.1
Spence, M.W.2
-
52
-
-
0030694454
-
Myelin contains neutral sphingomyelinase activity that is stimulated by tumor necrosis factor-alpha
-
52. CHAKRABORTY G, ZIEMBA S, DRIVAS A, LEDEEN RW: Myelin contains neutral sphingomyelinase activity that is stimulated by tumor necrosis factor-alpha. J Neurosci Res 50:466-476, 1997
-
(1997)
J Neurosci Res
, vol.50
, pp. 466-476
-
-
Chakraborty, G.1
Ziemba, S.2
Drivas, A.3
Ledeen, R.W.4
-
53
-
-
0029122709
-
Degradation of fluorescent and radiolabelled sphingomyelins in intact cells by a non-lysosomal pathway
-
12358
-
53. LEVADE T, VIDAL F, VESMEERSCH S, ANDRIEU N, GATT S, SALVAYRE R: Degradation of fluorescent and radiolabelled sphingomyelins in intact cells by a non-lysosomal pathway. Biochim Biophys Acta 12358:277-287, 1995
-
(1995)
Biochim Biophys Acta
, pp. 277-287
-
-
Levade, T.1
Vidal, F.2
Vesmeersch, S.3
Andrieu, N.4
Gatt, S.5
Salvayre, R.6
-
54
-
-
0014663246
-
The presence of spingomyelin and ceramide-cleaving enzymes in the small intestinal tract
-
54. NILSSON A: The presence of spingomyelin and ceramide-cleaving enzymes in the small intestinal tract. Biochim Biophys Acta 176:339-347, 1969
-
(1969)
Biochim Biophys Acta
, vol.176
, pp. 339-347
-
-
Nilsson, A.1
-
55
-
-
0030828425
-
Purification of a newly identified alkaline sphingomyelinase in human bile and effects of bile salts and phosphatidylcholine on enzyme activity
-
55. DUAN RD, NILSSON A: Purification of a newly identified alkaline sphingomyelinase in human bile and effects of bile salts and phosphatidylcholine on enzyme activity. Hepatology 26:823-830, 1997
-
(1997)
Hepatology
, vol.26
, pp. 823-830
-
-
Duan, R.D.1
Nilsson, A.2
-
56
-
-
0025819971
-
Human acid sphingomyelinase: Isolation, nucleotide sequence and expression of the full-length and alternatively spliced cDNAs
-
56. SCHUCHMAN EH, SUCHI M, TAKAHASHI T, SANDHOFF K, DESNICK RJ: Human acid sphingomyelinase: Isolation, nucleotide sequence and expression of the full-length and alternatively spliced cDNAs. J Biol Chem 266:8531-8539, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 8531-8539
-
-
Schuchman, E.H.1
Suchi, M.2
Takahashi, T.3
Sandhoff, K.4
Desnick, R.J.5
-
57
-
-
0032540959
-
The cellular trafficking and zinc dependence of secretory and lysosomal sphingomyelinase, two products of the acid sphingomyelinase gene
-
57. SCHISSEL SL, KEESLER GA, SCHUCHMAN EH, WILLIAMS KJ, TABAS I: The cellular trafficking and zinc dependence of secretory and lysosomal sphingomyelinase, two products of the acid sphingomyelinase gene. J Biol Chem 273:18240-18259, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 18240-18259
-
-
Schissel, S.L.1
Keesler, G.A.2
Schuchman, E.H.3
Williams, K.J.4
Tabas, I.5
-
58
-
-
0032584153
-
Cloned mammalian neutral sphingomyelinase: Functions in sphingolipid signaling?
-
58. TOMIUK S, HOFMANN K, NIX M, ZUMBANSEN M, STOFFEL W: Cloned mammalian neutral sphingomyelinase: Functions in sphingolipid signaling? Proc Natl Acad Sci USA 95:3638-3643, 1998
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3638-3643
-
-
Tomiuk, S.1
Hofmann, K.2
Nix, M.3
Zumbansen, M.4
Stoffel, W.5
-
59
-
-
0007544439
-
MDR1 P-glycoprotein specifically translocates phosphatidylcholine
-
59. VAN HELVOORT A, SMITH AJ, SPRONG H, FRITZSCHE I, SCHINKEL AH, BORST P, VAN MEER G: MDR1 P-glycoprotein specifically translocates phosphatidylcholine. Cell 87:507-517, 1996
-
(1996)
Cell
, vol.87
, pp. 507-517
-
-
Van Helvoort, A.1
Smith, A.J.2
Sprong, H.3
Fritzsche, I.4
Schinkel, A.H.5
Borst, P.6
Van Meer, G.7
-
60
-
-
0029761340
-
Accumulation of glucosylceramides in multidrug-resistant cancer cells
-
60. LAVIE Y, CAO HT, BURSTEN SL, GIULIANO AE, CABOT MC: Accumulation of glucosylceramides in multidrug-resistant cancer cells. J Biol Chem 271:19530-19536, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 19530-19536
-
-
Lavie, Y.1
Cao, H.T.2
Bursten, S.L.3
Giuliano, A.E.4
Cabot, M.C.5
-
61
-
-
0022974603
-
Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets
-
61. HANNUN YA, LOOMIS CR, MERRILL AH, BELL RM: Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets. J Biol Chem 261:12604-12609, 1986
-
(1986)
J Biol Chem
, vol.261
, pp. 12604-12609
-
-
Hannun, Y.A.1
Loomis, C.R.2
Merrill, A.H.3
Bell, R.M.4
-
62
-
-
0024795059
-
Sphingomyelin turnover induced by vitamin D3 in HL-60 cells: Role in cell differentiation
-
62. OKAZAKI T, BELL RM, HANNUN YA: Sphingomyelin turnover induced by vitamin D3 in HL-60 cells: Role in cell differentiation. J Biol Chem 264:19076-19080, 1989
-
(1989)
J Biol Chem
, vol.264
, pp. 19076-19080
-
-
Okazaki, T.1
Bell, R.M.2
Hannun, Y.A.3
-
63
-
-
0027994349
-
The sphingomyelin cycle and the second messenger function of ceramide
-
63. HANNUN YA: The sphingomyelin cycle and the second messenger function of ceramide. J Biol Chem 269:3125-3128, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 3125-3128
-
-
Hannun, Y.A.1
-
64
-
-
0023138332
-
Lysosphingolipids inhibit protein kinase C: Implications for the sphingolipidoses
-
64. HANNUN YA, BELL RM: Lysosphingolipids inhibit protein kinase C: Implications for the sphingolipidoses. Science 235:670-674, 1987
-
(1987)
Science
, vol.235
, pp. 670-674
-
-
Hannun, Y.A.1
Bell, R.M.2
-
65
-
-
0031880177
-
Sphingosine-1-phosphate in cell growth and cell death
-
65. SPIEGEL S, CUVILLIER O, EDSALL LC, KOHAMA T, MENZELEEV R, OLAH Z, OLIVERA A, PIRIANOV G, THOMAS DM, TU Z, VAN BROOKLYN JR, WANG F: Sphingosine-1-phosphate in cell growth and cell death. Ann NY Acad Sci 845:11-18, 1998
-
(1998)
Ann NY Acad Sci
, vol.845
, pp. 11-18
-
-
Spiegel, S.1
Cuvillier, O.2
Edsall, L.C.3
Kohama, T.4
Menzeleev, R.5
Olah, Z.6
Olivera, A.7
Pirianov, G.8
Thomas, D.M.9
Tu, Z.10
Van Brooklyn, J.R.11
Wang, F.12
-
66
-
-
0029014026
-
Short-chain ceramide-1-phosphates are novel stimulators of DNA synthesis and cell division: Antagonism by cell-permeable ceramides
-
66. GOMEZ-MUNOZ A, DUFFY PA, MARTIN A, O'BRIEN L, BYUN HS, BITTMAN R, BRINDLEY DN: Short-chain ceramide-1-phosphates are novel stimulators of DNA synthesis and cell division: Antagonism by cell-permeable ceramides. Mol Pharmacol 47:833-839, 1995
-
(1995)
Mol Pharmacol
, vol.47
, pp. 833-839
-
-
Gomez-Munoz, A.1
Duffy, P.A.2
Martin, A.3
O'Brien, L.4
Byun, H.S.5
Bittman, R.6
Brindley, D.N.7
-
67
-
-
0028108015
-
Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling
-
67. WIEGMANN K, SCHÜTZE S, MACHLEIDT T, WITTE D, KRONKE M: Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling. Cell 78:1005-1015, 1994
-
(1994)
Cell
, vol.78
, pp. 1005-1015
-
-
Wiegmann, K.1
Schütze, S.2
Machleidt, T.3
Witte, D.4
Kronke, M.5
-
68
-
-
0028292774
-
Dissociation of endogenous cellular ceramide from NK-kappa B activation
-
68. BETTS JC, AGRANOFF AB, NABEL GJ, SHAYMAN JA: Dissociation of endogenous cellular ceramide from NK-kappa B activation. J Biol Chem 269:8455-8458, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 8455-8458
-
-
Betts, J.C.1
Agranoff, A.B.2
Nabel, G.J.3
Shayman, J.A.4
-
69
-
-
0026726492
-
2 production and sphingomyelin metabolism: Evidence for the regulation of cyclooxzygenase gene expression by sphingosine and ceramide
-
2 production and sphingomyelin metabolism: Evidence for the regulation of cyclooxzygenase gene expression by sphingosine and ceramide. J Biol Chem 267:20044-20050, 1992
-
(1992)
J Biol Chem
, vol.267
, pp. 20044-20050
-
-
Ballou, L.R.1
Chao, C.P.2
Holness, M.A.3
Barker, S.C.4
Raghow, R.5
-
70
-
-
0347537940
-
Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis
-
70. VERHEIJ M, BOSE R, LIN XH, YAO B, JARVIS WD, GRANT S, BIRRER MJ, SZABO E, ZON LI, KYRIAKIS JM, HAIMOVITZ-FRIEDMAN A, FUKS Z, KOLESNICK RN: Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis. Nature 380:75-79, 1996
-
(1996)
Nature
, vol.380
, pp. 75-79
-
-
Verheij, M.1
Bose, R.2
Lin, X.H.3
Yao, B.4
Jarvis, W.D.5
Grant, S.6
Birrer, M.J.7
Szabo, E.8
Zon, L.I.9
Kyriakis, J.M.10
Haimovitz-Friedman, A.11
Fuks, Z.12
Kolesnick, R.N.13
-
71
-
-
0029148660
-
Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
-
71. BOSE R, VERHEIJ M, HAIMOVITZ-FRIEDMAN A, SCOTTO K, FUKS Z, KOLESNICK R: Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell 82:405-414, 1995
-
(1995)
Cell
, vol.82
, pp. 405-414
-
-
Bose, R.1
Verheij, M.2
Haimovitz-Friedman, A.3
Scotto, K.4
Fuks, Z.5
Kolesnick, R.6
-
72
-
-
0028810984
-
Low temperatures and hypertonicity do not block cytokine-induced stimulation of the sphingomyelin pathway but inhibit nuclear factor-kappa B activation
-
72. ANDRIEU N, SALVAYRE R, JAFFREZOU JP, LEVADE T: Low temperatures and hypertonicity do not block cytokine-induced stimulation of the sphingomyelin pathway but inhibit nuclear factor-kappa B activation. J Biol Chem 270:24518-24524, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 24518-24524
-
-
Andrieu, N.1
Salvayre, R.2
Jaffrezou, J.P.3
Levade, T.4
-
73
-
-
15444339428
-
Ceramide regulates the transcription of cyclooxygenase-2: Evidence for involvement of extracellular signal-regulated kinase/c-Jun N-terminal kinase and p38 mitogen-activated protein kinase pathways
-
73. SUBBARAMAIAH K, CHUNG WJ, DANNENBERG AJ: Ceramide regulates the transcription of cyclooxygenase-2: Evidence for involvement of extracellular signal-regulated kinase/c-Jun N-terminal kinase and p38 mitogen-activated protein kinase pathways. J Biol Chem 273:32943-32949, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 32943-32949
-
-
Subbaramaiah, K.1
Chung, W.J.2
Dannenberg, A.J.3
-
74
-
-
0029558130
-
Ceramide formation during heat shock: A potential mediator of alpha B-crystallin transcription
-
74. CHANG Y, ABE A, SHAYMAN JA: Ceramide formation during heat shock: A potential mediator of alpha B-crystallin transcription. Proc Natl Acad Sci USA 92:12275-12279, 1995
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 12275-12279
-
-
Chang, Y.1
Abe, A.2
Shayman, J.A.3
-
75
-
-
0029918136
-
Regulatory role of ceramide in interleukin (IL)-1-beta-induced E-selectin expression in human umbilical vein endothelial cells: Ceramide enhances IL-1 beta action, but is not sufficient for E-selectin expression
-
75. MASAMUNE A, IGARASHI Y, HAKOMORI S: Regulatory role of ceramide in interleukin (IL)-1-beta-induced E-selectin expression in human umbilical vein endothelial cells: Ceramide enhances IL-1 beta action, but is not sufficient for E-selectin expression. J Biol Chem 271:9368-9375, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 9368-9375
-
-
Masamune, A.1
Igarashi, Y.2
Hakomori, S.3
-
76
-
-
0027461121
-
Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta
-
76. MATHIAS S, YOUNES A, KAN CC, ORLOW I, JOSEPH C, KOLESNICK RN: Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta. Science 259:519-522, 1993
-
(1993)
Science
, vol.259
, pp. 519-522
-
-
Mathias, S.1
Younes, A.2
Kan, C.C.3
Orlow, I.4
Joseph, C.5
Kolesnick, R.N.6
-
77
-
-
0027371722
-
Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens
-
77. OLIVERA A, SPIEGEL S: Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature 365:557-560, 1993
-
(1993)
Nature
, vol.365
, pp. 557-560
-
-
Olivera, A.1
Spiegel, S.2
-
78
-
-
0029948396
-
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
-
78. CUVILLIER O, PIRIANOV G, KLEUSER B, VANEK PG, COSO OA, GUTKIND S, SPIEGEL S: Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature 381:800-803, 1996
-
(1996)
Nature
, vol.381
, pp. 800-803
-
-
Cuvillier, O.1
Pirianov, G.2
Kleuser, B.3
Vanek, P.G.4
Coso, O.A.5
Gutkind, S.6
Spiegel, S.7
-
79
-
-
0028070326
-
Identification of arachidonic acid as a mediator of sphingomyelin hydrolysis in response to tumor necrosis factor alpha
-
79. JAYADEV S, LINARDIC CM, HANNUN YA: Identification of arachidonic acid as a mediator of sphingomyelin hydrolysis in response to tumor necrosis factor alpha. J Biol Chem 269:5757-5763, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 5757-5763
-
-
Jayadev, S.1
Linardic, C.M.2
Hannun, Y.A.3
-
80
-
-
0027669148
-
Sphingolipids as mediators of effects of platelet-derived growth factor in vascular smooth muscle cells
-
80. JACOBS LS, KESTER M: Sphingolipids as mediators of effects of platelet-derived growth factor in vascular smooth muscle cells. Am J Physiol 265:C740-C747, 1993
-
(1993)
Am J Physiol
, vol.265
-
-
Jacobs, L.S.1
Kester, M.2
-
81
-
-
0028357057
-
Growth-dependent regulation of cellular ceramides in human T-cells
-
81. BORCHARDT RA, LEE WT, KALEN A, BUCKLEY RH, PETERS C, SCHIFF S, BELL RM: Growth-dependent regulation of cellular ceramides in human T-cells. Biochim Biophys Acta 1212:327-336, 1994
-
(1994)
Biochim Biophys Acta
, vol.1212
, pp. 327-336
-
-
Borchardt, R.A.1
Lee, W.T.2
Kalen, A.3
Buckley, R.H.4
Peters, C.5
Schiff, S.6
Bell, R.M.7
-
82
-
-
0026007737
-
Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon: Specific role in cell differentiation
-
82. KIM MY, LINARDIC C, OBEID L, HANNUN Y: Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon: Specific role in cell differentiation. J Biol Chem 266:484-489, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 484-489
-
-
Kim, M.Y.1
Linardic, C.2
Obeid, L.3
Hannun, Y.4
-
83
-
-
0029090337
-
Neurotrophins induce sphingomyelin hydrolysis. Modulation by co-expression of p75NTR with Trk receptors
-
83. DOBROWSKY RT, JENKINS GM, HANNUN YA: Neurotrophins induce sphingomyelin hydrolysis. Modulation by co-expression of p75NTR with Trk receptors. J Biol Chem 270:22135-22142, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 22135-22142
-
-
Dobrowsky, R.T.1
Jenkins, G.M.2
Hannun, Y.A.3
-
84
-
-
0028050242
-
Ceramide mediates the apoptotic response of WEHI231 cells to anti-immunoglobulin, corticosteroids and irradiation
-
84. QUINTANS J, KILKUS J, MCSHAN CL, GOTTSCHALK AR, DAWSON G: Ceramide mediates the apoptotic response of WEHI231 cells to anti-immunoglobulin, corticosteroids and irradiation. Biochem Biophys Res Commun 202:710-714, 1994
-
(1994)
Biochem Biophys Res Commun
, vol.202
, pp. 710-714
-
-
Quintans, J.1
Kilkus, J.2
McShan, C.L.3
Gottschalk, A.R.4
Dawson, G.5
-
85
-
-
0029069765
-
Ceramide triggers meoitic cell cycle progression in Xenopus oocytes: A potential mediator of progesterone-induced maturation
-
85. STRUM JC, SWENSON KI, TURNER JE, BELL RM: Ceramide triggers meoitic cell cycle progression in Xenopus oocytes: A potential mediator of progesterone-induced maturation. J Biol Chem 270: 13541-13547, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 13541-13547
-
-
Strum, J.C.1
Swenson, K.I.2
Turner, J.E.3
Bell, R.M.4
-
86
-
-
0030562067
-
The vitamin D3 analogue, calcipotriol, induces sphingomyelin hydrolysis in human keratinocytes
-
86. GEILEN CC, BEKTAS M, WIEDER T, ORFANOS CE: The vitamin D3 analogue, calcipotriol, induces sphingomyelin hydrolysis in human keratinocytes. FEBS Lett 378:88-92, 1996
-
(1996)
FEBS Lett
, vol.378
, pp. 88-92
-
-
Geilen, C.C.1
Bektas, M.2
Wieder, T.3
Orfanos, C.E.4
-
87
-
-
0029868202
-
Bradykinin increases ceramide and sphingosine content in human fibroblasts: Possible involvement of glycosphingolipids
-
87. MEACCI E, VASTA V, FARNARARO M, BRUNI P: Bradykinin increases ceramide and sphingosine content in human fibroblasts: Possible involvement of glycosphingolipids. Biochem Biophys Res Commun 221:1-7, 1996
-
(1996)
Biochem Biophys Res Commun
, vol.221
, pp. 1-7
-
-
Meacci, E.1
Vasta, V.2
Farnararo, M.3
Bruni, P.4
-
88
-
-
0028856675
-
A mediator role of ceramide in the regulation of neuroblastoma Neuro2a cell differentiation
-
88. RIBONI L, PRINETTI A, BASSI R, CAMINITI A, TETTAMANTI G: A mediator role of ceramide in the regulation of neuroblastoma Neuro2a cell differentiation. J Biol Chem 270:26868-26875, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 26868-26875
-
-
Riboni, L.1
Prinetti, A.2
Bassi, R.3
Caminiti, A.4
Tettamanti, G.5
-
89
-
-
0030582729
-
Involvement of sphingolipids in the endothelin-1 signal transduction mechanism in rat brain
-
89. CATALAN RE, ARAGONES MD, MARTINEZ AM, FERNANDEZ I: Involvement of sphingolipids in the endothelin-1 signal transduction mechanism in rat brain. Neurosci Lett 220:121-124, 1996
-
(1996)
Neurosci Lett
, vol.220
, pp. 121-124
-
-
Catalan, R.E.1
Aragones, M.D.2
Martinez, A.M.3
Fernandez, I.4
-
90
-
-
0028095477
-
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase
-
90. CIFONE MG, MARIA R, RONCAIOLI P, RIPPO MR, AZUMA M, LANIER LL, SANTONI A, TESTI R: Apoptotic signaling through CD95 (Fas/ Apo-1) activates an acidic sphingomyelinase. J Exp Med 180: 1547-1552, 1994
-
(1994)
J Exp Med
, vol.180
, pp. 1547-1552
-
-
Cifone, M.G.1
Maria, R.2
Roncaioli, P.3
Rippo, M.R.4
Azuma, M.5
Lanier, L.L.6
Santoni, A.7
Testi, R.8
-
91
-
-
0029036715
-
CD28 signals through acidic sphingomyelinase
-
91. BOUCHER LM, WIEGMANN K, FUTTERER A, PFEFFER K, MACHLEIDT T, SCHUTZE S, MAK TW, KRONKE M: CD28 signals through acidic sphingomyelinase. J Exp Med 181:2059-2068, 1995
-
(1995)
J Exp Med
, vol.181
, pp. 2059-2068
-
-
Boucher, L.M.1
Wiegmann, K.2
Futterer, A.3
Pfeffer, K.4
Machleidt, T.5
Schutze, S.6
Mak, T.W.7
Kronke, M.8
-
92
-
-
0029965928
-
Tumor cell resistance to apoptosis due to a defect in the activation of sphingomyelinase and the 24 kDa apoptotic protease (AP24)
-
92. WRIGHT SC, ZHENG H, ZHONG J: Tumor cell resistance to apoptosis due to a defect in the activation of sphingomyelinase and the 24 kDa apoptotic protease (AP24). FASEB J 10:325-332, 1996
-
(1996)
FASEB J
, vol.10
, pp. 325-332
-
-
Wright, S.C.1
Zheng, H.2
Zhong, J.3
-
93
-
-
0024405793
-
Accumulation of ceramide in ischemic human brain of an acute case of cerebral occlusion
-
93. KUBOTA M, KITAHARA S, SHIMASAKI H, UETA N: Accumulation of ceramide in ischemic human brain of an acute case of cerebral occlusion. Jpn J Exp Med 59:59-64, 1989
-
(1989)
Jpn J Exp Med
, vol.59
, pp. 59-64
-
-
Kubota, M.1
Kitahara, S.2
Shimasaki, H.3
Ueta, N.4
-
94
-
-
0026335117
-
1,2-Diacylglyerol and ceramide levels in rat liver and skeletal muscle in vivo
-
94. TURINSKY J, BAYLY BP, O'SULLIVAN DM: 1,2-Diacylglyerol and ceramide levels in rat liver and skeletal muscle in vivo. Am J Physiol 261:E620-E627, 1991
-
(1991)
Am J Physiol
, vol.261
-
-
Turinsky, J.1
Bayly, B.P.2
Sullivan, D.M.3
-
95
-
-
0030006040
-
Daunorubicin-induced apoptosis: Triggering of ceramide generation through sphingomyelin hydrolysis
-
95. JAFFREZOU JP, LEVADE T, BETTAIEB A, ANDRIEU N, BEZOMBES C, MAESTRE N, VERMEERSCH S, ROUSSE A, LAURENT G: Daunorubicin-induced apoptosis: Triggering of ceramide generation through sphingomyelin hydrolysis. EMBO J 15:2416-2427, 1996
-
(1996)
EMBO J
, vol.15
, pp. 2416-2427
-
-
Jaffrezou, J.P.1
Levade, T.2
Bettaieb, A.3
Andrieu, N.4
Bezombes, C.5
Maestre, N.6
Vermeersch, S.7
Rousse, A.8
Laurent, G.9
-
96
-
-
9344222195
-
Bcl-2 interrupts the ceramide-mediated pathway of cell death
-
96. ZHANG J, ALTER N, REED JC, BORNER C, OBEID LM, HANNUN YA: Bcl-2 interrupts the ceramide-mediated pathway of cell death. Proc Natl Acad Sci USA 93:5325-5328, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5325-5328
-
-
Zhang, J.1
Alter, N.2
Reed, J.C.3
Borner, C.4
Obeid, L.M.5
Hannun, Y.A.6
-
97
-
-
0028176730
-
1-beta-D-Arabino-furanosylcytosine stimulates ceramide and diglyceride formation in HL-60 cells
-
97. STRUM JC, SMALL GW, PAUIG SB, DANIEL LW: 1-beta-D-Arabino-furanosylcytosine stimulates ceramide and diglyceride formation in HL-60 cells. J Biol Chem 269:15493-15497, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 15493-15497
-
-
Strum, J.C.1
Small, G.W.2
Pauig, S.B.3
Daniel, L.W.4
-
98
-
-
0030248842
-
Sphingoid bioregulators in the differentiation of cells of neural origin
-
98. TETTAMANTI G, PRINETTI A, BASSI R, VIANI P, GIUSSANI P, RIBONI L: Sphingoid bioregulators in the differentiation of cells of neural origin. J Lipid Med Cell Signal 14:263-275, 1996
-
(1996)
J Lipid Med Cell Signal
, vol.14
, pp. 263-275
-
-
Tettamanti, G.1
Prinetti, A.2
Bassi, R.3
Viani, P.4
Giussani, P.5
Riboni, L.6
-
99
-
-
0025934998
-
Reversal of multidrug resistance by calcium channel blocker SR33557 without photoaffinity labeling of P-glycoprotein
-
99. JAFFREZOU JP, HERBERT JM, LEVADE T, GAU MN, CHATELAIN P, LARENT G: Reversal of multidrug resistance by calcium channel blocker SR33557 without photoaffinity labeling of P-glycoprotein. J Biol Chem 266:19858-19864, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 19858-19864
-
-
Jaffrezou, J.P.1
Herbert, J.M.2
Levade, T.3
Gau, M.N.4
Chatelain, P.5
Larent, G.6
-
100
-
-
0029889577
-
Protein kinase C inhibition induces apoptosis and ceramide production through activation of a neutral sphingomyelinase
-
100. CHMURA SJ, NODZENSKI E, WEICHSELBAUM RR, QUINTANS J: Protein kinase C inhibition induces apoptosis and ceramide production through activation of a neutral sphingomyelinase. Cancer Res 56:2711-2714, 1996
-
(1996)
Cancer Res
, vol.56
, pp. 2711-2714
-
-
Chmura, S.J.1
Nodzenski, E.2
Weichselbaum, R.R.3
Quintans, J.4
-
101
-
-
0026733541
-
Changes in bioactive lipids, aklylacylglycerol and ceramide, occur in HIV-infected cells
-
101. VAN VELDHOVEN PP, MATTHEWS TJ, BOLOGNESI DP, BELL RM: Changes in bioactive lipids, aklylacylglycerol and ceramide, occur in HIV-infected cells. Biochem Biophys Res Commun 187:209-216, 1992
-
(1992)
Biochem Biophys Res Commun
, vol.187
, pp. 209-216
-
-
Van Veldhoven, P.P.1
Matthews, T.J.2
Bolognesi, D.P.3
Bell, R.M.4
-
102
-
-
0030006201
-
Role of the ceramide-signaling pathway in cytokine responses to P-finbriated Escherichia coli
-
102. HEDLUND M, SVENSSON M, NILSSON A, DUAN RD, SVANBORG C: Role of the ceramide-signaling pathway in cytokine responses to P-finbriated Escherichia coli. J Exp Med 183:1037-1044, 1996
-
(1996)
J Exp Med
, vol.183
, pp. 1037-1044
-
-
Hedlund, M.1
Svensson, M.2
Nilsson, A.3
Duan, R.D.4
Svanborg, C.5
-
103
-
-
0030852331
-
Intracellular signaling events in CD77-mediated apoptosis of Burkitt's lymphoma cells
-
103. TAGA S, CARLIER K, MISHAL Z, CAPOULADE C, MANGENEY M, LECLUSE Y, COULAUD D, TETAUD C, PRITCHARD LL, TURSZ T, WIELS J: Intracellular signaling events in CD77-mediated apoptosis of Burkitt's lymphoma cells. Blood 90:2757-2767, 1997
-
(1997)
Blood
, vol.90
, pp. 2757-2767
-
-
Taga, S.1
Carlier, K.2
Mishal, Z.3
Capoulade, C.4
Mangeney, M.5
Lecluse, Y.6
Coulaud, D.7
Tetaud, C.8
Pritchard, L.L.9
Tursz, T.10
Wiels, J.11
-
104
-
-
0029932759
-
Interleukin-1 beta-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F
-
104. WELSH N: Interleukin-1 beta-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F. J Biol Chem 271:8307-8312, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 8307-8312
-
-
Welsh, N.1
-
105
-
-
0028790293
-
Regulation of cytochrome P4502C11 (CYP2C11) gene expression by interleukin-1, sphingomyelin hydrolysis, and ceramides in rat hepatocytes
-
105. CHEN J, NIKOLOVA-KARAKASHIAN M, MERRILL AH, MORGAN ET: Regulation of cytochrome P4502C11 (CYP2C11) gene expression by interleukin-1, sphingomyelin hydrolysis, and ceramides in rat hepatocytes. J Biol Chem 270:25233-25238, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 25233-25238
-
-
Chen, J.1
Nikolova-Karakashian, M.2
Merrill, A.H.3
Morgan, E.T.4
-
106
-
-
0028930638
-
Ceramide mediates tumor necrosis factor effects on P450-aromatase activity in cultured granulosa cells
-
106. SANTANA P, LLANES L, HERNANDEZ I, GALLARDO G, QUINTANA J, GONZALEZ J: Ceramide mediates tumor necrosis factor effects on P450-aromatase activity in cultured granulosa cells. Endocrinology 136:2345-2348, 1995
-
(1995)
Endocrinology
, vol.136
, pp. 2345-2348
-
-
Santana, P.1
Llanes, L.2
Hernandez, I.3
Gallardo, G.4
Quintana, J.5
Gonzalez, J.6
-
107
-
-
0026726492
-
Interleukin-1-mediated PGE2 production and sphingomyelin metabolism: Evidence for the regulation of cyclooxygenase gene expression by sphingosine and ceramide
-
107. BALLOU LR, CHAO CP, HOLNESS MA, BARKER SC, RAHOW R: Interleukin-1-mediated PGE2 production and sphingomyelin metabolism: Evidence for the regulation of cyclooxygenase gene expression by sphingosine and ceramide. J Biol Chem 267:20044-20050, 1992
-
(1992)
J Biol Chem
, vol.267
, pp. 20044-20050
-
-
Ballou, L.R.1
Chao, C.P.2
Holness, M.A.3
Barker, S.C.4
Rahow, R.5
-
108
-
-
0025942530
-
Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells: Evidence that ceramide may mediate sphingosine action
-
108. GOLDKORN T, DRESSLER KA, MUINDI J, RADIN NS, MENDELSOHN J, MENALDINO D, LIOTTA D, KOLESNICK RN: Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells: Evidence that ceramide may mediate sphingosine action. J Biol Chem 266:16092-16097, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 16092-16097
-
-
Goldkorn, T.1
Dressler, K.A.2
Muindi, J.3
Radin, N.S.4
Mendelsohn, J.5
Menaldino, D.6
Liotta, D.7
Kolesnick, R.N.8
-
109
-
-
0029671204
-
C2-ceramide primes specifically for the superoxide anion production induced by N-formylmethionylleucyl phenylalanine (fMLP) in human neutrophils
-
109. RICHARD A, BOURGOIN S, NACCACHE PH, L'HEUREUX GP, KRUM E, MCCOLL SR, PELLETIER G: C2-ceramide primes specifically for the Superoxide anion production induced by N-formylmethionylleucyl phenylalanine (fMLP) in human neutrophils. Biochim Biophys Acta 1299:259-266, 1996
-
(1996)
Biochim Biophys Acta
, vol.1299
, pp. 259-266
-
-
Richard, A.1
Bourgoin, S.2
Naccache, P.H.3
L'Heureux, G.P.4
Krum, E.5
McColl, S.R.6
Pelletier, G.7
-
110
-
-
0032568836
-
Involvement of de novo ceramide biosynthesis in tumor necrosis factor-alpha/cycloheximide-induced cerebral endothelial cell death
-
110. Xu J, YEH CH, CHEN S, HE L, SENSI SL, CANZONIERO LM, CHOI DW, HSU CY: Involvement of de novo ceramide biosynthesis in tumor necrosis factor-alpha/cycloheximide-induced cerebral endothelial cell death. J Biol Chem 273:16521-16526, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 16521-16526
-
-
Xu, J.1
Yeh, C.H.2
Chen, S.3
He, L.4
Sensi, S.L.5
Canzoniero, L.M.6
Choi, D.W.7
Hsu, C.Y.8
-
111
-
-
0032836990
-
Preferential killing of multidrug-resistant KB cells by inhibitors of glucosylceramide synthase
-
111. NICHOLSON KM, QUINN DM, KELLETT GL, WARR JR: Preferential killing of multidrug-resistant KB cells by inhibitors of glucosylceramide synthase. Br J Cancer 81:423-430, 1999
-
(1999)
Br J Cancer
, vol.81
, pp. 423-430
-
-
Nicholson, K.M.1
Quinn, D.M.2
Kellett, G.L.3
Warr, J.R.4
-
112
-
-
0344631722
-
Effect of N-acetylsphingosine (C2) and the ceramidase inhibitor (1S,2R)-D-erythro-2-(N-myristoylamino)-1-phenyl-1-propanol on the regulation of Sertoli cell function
-
112. MERONI SB, CANEPA DF, PELLIZZARI EH, SCHTEINGART HF, CIGORRAGA SB: Effect of N-acetylsphingosine (C2) and the ceramidase inhibitor (1S,2R)-D-erythro-2-(N-myristoylamino)-1-phenyl-1-propanol on the regulation of Sertoli cell function. J Androl 20:619-625, 1999
-
(1999)
J Androl
, vol.20
, pp. 619-625
-
-
Meroni, S.B.1
Canepa, D.F.2
Pellizzari, E.H.3
Schteingart, H.F.4
Cigorraga, S.B.5
-
113
-
-
0028817546
-
Induction of apoptotic DNA fragmentation and cell death by natural ceramide
-
113. JI L, ZHANG G, UEMATSU S, AKAHORI Y, HIRABAYASHI Y: Induction of apoptotic DNA fragmentation and cell death by natural ceramide. FEBS Lett 358:211-214, 1995
-
(1995)
FEBS Lett
, vol.358
, pp. 211-214
-
-
Ji, L.1
Zhang, G.2
Uematsu, S.3
Akahori, Y.4
Hirabayashi, Y.5
-
114
-
-
0027071756
-
Metabolic effects of short-chain ceramide and glucosolyceramide on sphingolipids and protein kinase C
-
114. ABE A, WU D, SHAYMAN JA, RADIN NS: Metabolic effects of short-chain ceramide and glucosolyceramide on sphingolipids and protein kinase C. Eur J Biochem 210:765-773, 1992
-
(1992)
Eur J Biochem
, vol.210
, pp. 765-773
-
-
Abe, A.1
Wu, D.2
Shayman, J.A.3
Radin, N.S.4
-
115
-
-
0344588823
-
Membrane-destabilizing properties of C2-ceramide may be responsible for its ability to inhibit platelet aggregation
-
115. SIMON CG JR, GEAR AR: Membrane-destabilizing properties of C2-ceramide may be responsible for its ability to inhibit platelet aggregation. Biochem 37:2059-2069, 1998
-
(1998)
Biochem
, vol.37
, pp. 2059-2069
-
-
Simon C.G., Jr.1
Gear, A.R.2
-
116
-
-
0030893370
-
Expression of neutral sphingomyelinase identifies a distinct pool of sphingomyelin involved in apoptosis
-
116. ZHANG P, LIU B, JENKINS GM, HANNUN YA, OBEID LM: Expression of neutral sphingomyelinase identifies a distinct pool of sphingomyelin involved in apoptosis. J Biol Chem 272:9609-9612, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 9609-9612
-
-
Zhang, P.1
Liu, B.2
Jenkins, G.M.3
Hannun, Y.A.4
Obeid, L.M.5
-
117
-
-
0028913218
-
Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth
-
117. ABE A, RADIN NS, SHAYMAN JA, WOTRING LL, ZIPKIN RE, SIVAKUMAR R, RUGGIERI JM, CARSON KG, GANEM B: Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth. J Lipid Res 36:611-612, 1995
-
(1995)
J Lipid Res
, vol.36
, pp. 611-612
-
-
Abe, A.1
Radin, N.S.2
Shayman, J.A.3
Wotring, L.L.4
Zipkin, R.E.5
Sivakumar, R.6
Ruggieri, J.M.7
Carson, K.G.8
Ganem, B.9
-
118
-
-
0032692477
-
Inhibitors of glucosylceramide synthase
-
118. SHAYMAN JA, LEE L, ABE A, SHU L: Inhibitors of glucosylceramide synthase. Methods Enzymol 311:373-387, 1999
-
(1999)
Methods Enzymol
, vol.311
, pp. 373-387
-
-
Shayman, J.A.1
Lee, L.2
Abe, A.3
Shu, L.4
-
119
-
-
9044222880
-
Fumonisin toxicity and sphingolipid biosynthesis
-
119. MERRILL AH JR, WANG E, VALES TR, SMITH ER, SCHROEDER JJ, MENALDINO DS, ALEXANDER C, CRANE HM, XIA J, LIOTTA DC, MEREDITH FI, RILEY RT: Fumonisin toxicity and sphingolipid biosynthesis. Adv Exp Med Biol 392:297-306, 1996
-
(1996)
Adv Exp Med Biol
, vol.392
, pp. 297-306
-
-
Merrill A.H., Jr.1
Wang, E.2
Vales, T.R.3
Smith, E.R.4
Schroeder, J.J.5
Menaldino, D.S.6
Alexander, C.7
Crane, H.M.8
Xia, J.9
Liotta, D.C.10
Meredith, F.I.11
Riley, R.T.12
-
120
-
-
17544366509
-
(1S,2R)-D-erythro-2-(N-myristoylamino)-1-phenyl-1-propanol as an inhibitor of ceramidase
-
120. BIELAWSKA A, GREENBERG MS, PERRY D, JAYADEV S, SHAYMAN J, MCKAY C, HANNUN YA: (1S,2R)-D-erythro-2-(N-myristoylamino)-1-phenyl-1-propanol as an inhibitor of ceramidase. J Biol Chem 271:12646-12654, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 12646-12654
-
-
Bielawska, A.1
Greenberg, M.S.2
Perry, D.3
Jayadev, S.4
Shayman, J.5
McKay, C.6
Hannun, Y.A.7
-
121
-
-
0027202552
-
Ceramide activates heterotrimeric protein phosphatase 2A
-
121. DOBROWSKY RT, KAMIBAYASHI C, MUMBY MC, HANNUN YA: Ceramide activates heterotrimeric protein phosphatase 2A. J Biol Chem 268:15523-15530, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 15523-15530
-
-
Dobrowsky, R.T.1
Kamibayashi, C.2
Mumby, M.C.3
Hannun, Y.A.4
-
122
-
-
0033050880
-
Analysis of phosphorylate sphingolipid long-chain bases reveals potential roles in heat stress and growth control in Saccharomyces
-
122. SKRZYPEK MS, NAGIEC MM, LESTER RL, DICKSON RC: Analysis of phosphorylate sphingolipid long-chain bases reveals potential roles in heat stress and growth control in Saccharomyces. J Bacterial 181:1134-1140, 1999
-
(1999)
J Bacterial
, vol.181
, pp. 1134-1140
-
-
Skrzypek, M.S.1
Nagiec, M.M.2
Lester, R.L.3
Dickson, R.C.4
-
123
-
-
0032103445
-
Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants
-
123. LANTERMANN MM, SABA JD: Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants. Biochem J 332:525-531, 1998
-
(1998)
Biochem J
, vol.332
, pp. 525-531
-
-
Lantermann, M.M.1
Saba, J.D.2
-
124
-
-
0030671394
-
The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase
-
124. SABA JC, NARA F, BIELAWSKA A, GARRETT S, HANNUN YA: The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase. J Biol Chem 272:26087-26090, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 26087-26090
-
-
Saba, J.C.1
Nara, F.2
Bielawska, A.3
Garrett, S.4
Hannun, Y.A.5
-
125
-
-
0033568278
-
The dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses
-
125. MAO C, SABA JD, OBEID LM: The dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses. Biochem J 342:667-675, 1999
-
(1999)
Biochem J
, vol.342
, pp. 667-675
-
-
Mao, C.1
Saba, J.D.2
Obeid, L.M.3
-
126
-
-
0026458406
-
TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown
-
126. SCHUTZ S, POTTHOFF K, MACHLEIDT T, BERKOVIC D, WIEGMANN K, KRONKE M: TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. Cell 71:765-776, 1992
-
(1992)
Cell
, vol.71
, pp. 765-776
-
-
Schutz, S.1
Potthoff, K.2
Machleidt, T.3
Berkovic, D.4
Wiegmann, K.5
Kronke, M.6
-
127
-
-
0030960327
-
Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione
-
127. LIU B, HANNUN YA: Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione. J Biol Chem 272:16281-16287, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 16281-16287
-
-
Liu, B.1
Hannun, Y.A.2
-
128
-
-
0032079524
-
Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death
-
128. LIU B, ANDRIEU-ABADIE N, LEVADE T, ZHANG P, OBEID LM, HANNUN YA: Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death. J Biol Chem 273:11313-11320, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 11313-11320
-
-
Liu, B.1
Andrieu-Abadie, N.2
Levade, T.3
Zhang, P.4
Obeid, L.M.5
Hannun, Y.A.6
-
129
-
-
0030595340
-
FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase
-
129. ADAM-KLAGES S, ADAM D, WIEGMANN K, STRUVE S, KOLANUS W, SCHNEIDER-MERGENER J, KRONKE M: FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase. Cell 86:937-947, 1996
-
(1996)
Cell
, vol.86
, pp. 937-947
-
-
Adam-Klages, S.1
Adam, D.2
Wiegmann, K.3
Struve, S.4
Kolanus, W.5
Schneider-Mergener, J.6
Kronke, M.7
-
130
-
-
0033600839
-
Differential coupling of the sphingosine 1-phosphate receptors edg-1, edg-3, and H218/Edg-5 to the g (i), g (q), and g (12) families of heterotrimeric G proteins
-
130. WINDH RT, LEE MJ, HLA T, AN S, BARR AJ, MANNING DR: Differential coupling of the sphingosine 1-phosphate receptors edg-1, edg-3, and H218/Edg-5 to the g (i), g (q), and G (12) families of heterotrimeric G proteins. J Biol Chem 274:27351-27358, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 27351-27358
-
-
Windh, R.T.1
Lee, M.J.2
Hla, T.3
An, S.4
Barr, A.J.5
Manning, D.R.6
-
131
-
-
0031729124
-
Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate
-
131. GOETZL EJ, AN S: Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate. FASEB J 12:1589-1598, 1998
-
(1998)
FASEB J
, vol.12
, pp. 1589-1598
-
-
Goetzl, E.J.1
An, S.2
-
132
-
-
0029079324
-
Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism
-
132. WU J, SPIEGEL S, STURGILL TW: Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism. J Biol Chem 270:11484-11488, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 11484-11488
-
-
Wu, J.1
Spiegel, S.2
Sturgill, T.W.3
-
133
-
-
0032538463
-
2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition
-
2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition. J Biol Chem 273:27104-27110, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 27104-27110
-
-
Okamato, H.1
Takuwa, N.2
Gonda, K.3
Okazaki, H.4
Chang, K.5
Yatomi, Y.6
Shigematsu, H.7
Takuwa, Y.8
-
134
-
-
0033603341
-
Effect of Rho and ADP-ribosylation factor GTPases on phospholipase D activity in intact human adenocarcinoma A549 cells
-
134. MEACCI E, VASTA V, MOORMAN JP, BOBAK DA, BRUNI P, MOSS J, VAUGHAN M: Effect of Rho and ADP-ribosylation factor GTPases on phospholipase D activity in intact human adenocarcinoma A549 cells. J Biol Chem 274:18605-18612, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 18605-18612
-
-
Meacci, E.1
Vasta, V.2
Moorman, J.P.3
Bobak, D.A.4
Bruni, P.5
Moss, J.6
Vaughan, M.7
-
136
-
-
2642630721
-
2+ signalling by G-protein-coupled receptors
-
2+ signalling by G-protein-coupled receptors. EMBO J 17:2830-2837, 1998
-
(1998)
EMBO J
, vol.17
, pp. 2830-2837
-
-
Meyer Zu Heringdorf, D.1
Lass, H.2
Alemany, R.3
Laser, K.T.4
Neumann, E.5
Zhang, C.6
Schmidt, M.7
Rauen, U.8
Jakobs, K.H.9
Van Koppen, C.J.10
-
137
-
-
0032489574
-
Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1
-
137. LEE MJ, VAN BROOKLYN JR, THANGADA S, LIU CH, HAND AR, MENZELEEV R, SPIEGEL S, HLA T: Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science 269:1552-1555, 1998
-
(1998)
Science
, vol.269
, pp. 1552-1555
-
-
Lee, M.J.1
Van Brooklyn, J.R.2
Thangada, S.3
Liu, C.H.4
Hand, A.R.5
Menzeleev, R.6
Spiegel, S.7
Hla, T.8
-
138
-
-
0033516586
-
Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5
-
138. ANCILLIN N, HLA T: Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5. J Biol Chem 274:18997-19902, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 18997-19902
-
-
Ancillin, N.1
Hla, T.2
-
139
-
-
0028128763
-
Sphingosine 1-phosphate generated in the endoplasmic reticulum membrane activates release of stored calcium
-
139. GHOSH TK, BIAN J, GILL DL: Sphingosine 1-phosphate generated in the endoplasmic reticulum membrane activates release of stored calcium. J Biol Chem 269:22628-22635, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 22628-22635
-
-
Ghosh, T.K.1
Bian, J.2
Gill, D.L.3
-
140
-
-
0030592536
-
Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity
-
140. BUEHRER BM, BARDES ES, BELL RM: Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity. Biochim Biophys Acta 1303:233-242, 1996
-
(1996)
Biochim Biophys Acta
, vol.1303
, pp. 233-242
-
-
Buehrer, B.M.1
Bardes, E.S.2
Bell, R.M.3
-
141
-
-
0030891014
-
Divergence in signal transduction pathways of platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) receptors: Involvement of sphingosine 1-phosphate in PDGF but not EGF signaling
-
141. RANI CS, WANG F, FUIOR E, BERGER A, WU J, STURGILL TW, LEROITH D, VARTICOVSKI L, SPIEGEL S: Divergence in signal transduction pathways of platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) receptors: Involvement of sphingosine 1-phosphate in PDGF but not EGF signaling. J Biol Chem 272:10777-10783, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 10777-10783
-
-
Rani, C.S.1
Wang, F.2
Fuior, E.3
Berger, A.4
Wu, J.5
Sturgill, T.W.6
LeRoith, D.7
Varticovski, L.8
Spiegel, S.9
-
142
-
-
0032540010
-
FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking
-
142. MELENDEZ A, FLOTO RA, GILLOOLY DJ, HARNETT MM, ALLEN JM: FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking. J Biol Chem 273:9393-9403, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 9393-9403
-
-
Melendez, A.1
Floto, R.A.2
Gillooly, D.J.3
Harnett, M.M.4
Allen, J.M.5
-
143
-
-
0032530864
-
N,N-dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: Modulation of cellular levels of sphingosine 1-kinase and ceramide
-
143. EDSALL LC, VAN BROOKLYN JR, CUVILLIER O, KLEUSER B, SPIEGEL SN: N,N-dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: Modulation of cellular levels of sphingosine 1-kinase and ceramide. Biochemistry 37:12892-12898, 1998
-
(1998)
Biochemistry
, vol.37
, pp. 12892-12898
-
-
Edsall, L.C.1
Van Brooklyn, J.R.2
Cuvillier, O.3
Kleuser, B.4
Spiegel, S.N.5
-
144
-
-
0032508379
-
Purification and characterization of ceramide-activated protein phosphatases
-
144. GALARDI S, KISHIKAWA K, KAMIBAYASHI C, MUMBY MC, HANNUM YA: Purification and characterization of ceramide-activated protein phosphatases. Biochemistry 37:11232-11238, 1998
-
(1998)
Biochemistry
, vol.37
, pp. 11232-11238
-
-
Galardi, S.1
Kishikawa, K.2
Kamibayashi, C.3
Mumby, M.C.4
Hannum, Y.A.5
-
145
-
-
0029915925
-
A ceramide-activated protein phosphatase mediates ceramide-induced G1 arrest of Saccharomyces cerevisiae
-
145. NICKELS JT, BROACH JR: A ceramide-activated protein phosphatase mediates ceramide-induced G1 arrest of Saccharomyces cerevisiae. Genes Dev 10:382-394, 1996
-
(1996)
Genes Dev
, vol.10
, pp. 382-394
-
-
Nickels, J.T.1
Broach, J.R.2
-
146
-
-
0033575310
-
Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A: Activation is stereo-specific and regulated by phopshatidic acid
-
146. CHALFANT CE, KISHIKAWA K, MUMBY MC, KAMIBAYASHI C, BIELAWSKA A, HANNUN YA: Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A: Activation is stereo-specific and regulated by phopshatidic acid. J Biol Chem 274: 20313-20317, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 20313-20317
-
-
Chalfant, C.E.1
Kishikawa, K.2
Mumby, M.C.3
Kamibayashi, C.4
Bielawska, A.5
Hannun, Y.A.6
-
147
-
-
0028934811
-
Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest
-
147. DBAIBO GS, PUSHKAREVA MY, JAYADEV S, SCHWARZ JK, HOROWITZ JM, OBEID LM, HANNUN YA: Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest. Proc Natl Acad Sci USA 92:1347-1351, 1995
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1347-1351
-
-
Dbaibo, G.S.1
Pushkareva, M.Y.2
Jayadev, S.3
Schwarz, J.K.4
Horowitz, J.M.5
Obeid, L.M.6
Hannun, Y.A.7
-
148
-
-
0343742670
-
Kinase suppressor of Ras is ceramide-activated protein kinase
-
148. ZHANG Y, YAO B, DELIKAT S, BAYOUMY S, LIN XH, BASU S, MCGINLEY M, CHAN-HUI PY, LICHENSTEIN H, KOLESNICK R: Kinase suppressor of Ras is ceramide-activated protein kinase. Cell 89:63-72, 1997
-
(1997)
Cell
, vol.89
, pp. 63-72
-
-
Zhang, Y.1
Yao, B.2
Delikat, S.3
Bayoumy, S.4
Lin, X.H.5
Basu, S.6
McGinley, M.7
Chan-Hui, P.Y.8
Lichenstein, H.9
Kolesnick, R.10
-
149
-
-
0027461121
-
Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta
-
149. MATHIAS S, YOUNES A, KAN CC, ORLOW I, JOSEPH C, KOLESNICK RN: Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta. Science 259:519-522, 1993
-
(1993)
Science
, vol.259
, pp. 519-522
-
-
Mathias, S.1
Younes, A.2
Kan, C.C.3
Orlow, I.4
Joseph, C.5
Kolesnick, R.N.6
-
150
-
-
0029003788
-
PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid
-
150. MULLER G, AYOUB M, STORZ P, RENNECKE J, FABBRO D, PFIZENMAIER K: PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid. EMBO J 14:1961-1969, 1995
-
(1995)
EMBO J
, vol.14
, pp. 1961-1969
-
-
Muller, G.1
Ayoub, M.2
Storz, P.3
Rennecke, J.4
Fabbro, D.5
Pfizenmaier, K.6
-
151
-
-
0033214095
-
Cathepsin D targeted by acid sphingomyelinase-derived ceramide
-
151. HEINRICH M, WICKEL M, SCHNEIDER-BRACHERT W, SANDBERG C, GAHR J, SCHWANDNER R, WEBER T, SAFTIG P, PETERS C, BRUNNER J, KRONKE M, SCHUTZE S: Cathepsin D targeted by acid sphingomyelinase-derived ceramide. EMBO J 18:5252-5263, 1999
-
(1999)
EMBO J
, vol.18
, pp. 5252-5263
-
-
Heinrich, M.1
Wickel, M.2
Schneider-Brachert, W.3
Sandberg, C.4
Gahr, J.5
Schwandner, R.6
Weber, T.7
Saftig, P.8
Peters, C.9
Brunner, J.10
Kronke, M.11
Schutze, S.12
-
152
-
-
0027511687
-
Programmed cell death induced by ceramide
-
152. OBEID LM, LINARDIC CM, KAROLAK LA, HANNUN YA: Programmed cell death induced by ceramide. Science 259:1769-1771, 1993
-
(1993)
Science
, vol.259
, pp. 1769-1771
-
-
Obeid, L.M.1
Linardic, C.M.2
Karolak, L.A.3
Hannun, Y.A.4
-
153
-
-
0032797821
-
Inhibition of neutral sphingomyelinase activation and ceramide formation by glutathione in hypoxic PC12 cell death
-
153. YOSHIMURA S, BANNO Y, NAKASHIMA S, HAYASHI K, YAMAKAWA H, SAWADA M, SAKAI N, NOZAWA Y: Inhibition of neutral sphingomyelinase activation and ceramide formation by glutathione in hypoxic PC12 cell death. J Neurochem 73:675-683, 1999
-
(1999)
J Neurochem
, vol.73
, pp. 675-683
-
-
Yoshimura, S.1
Banno, Y.2
Nakashima, S.3
Hayashi, K.4
Yamakawa, H.5
Sawada, M.6
Sakai, N.7
Nozawa, Y.8
-
154
-
-
16044364385
-
Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis
-
154. SANTANA P, PENA LA, HAIMOVITZ-FRIEDMAN A, MARTIN S, GREEN D, MCLOUGHLIN M, CORDON-CARDO C, SCHUCHMAN EH, FUKS Z, KOLESNICK R: Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. Cell 86:189-199, 1996
-
(1996)
Cell
, vol.86
, pp. 189-199
-
-
Santana, P.1
Pena, L.A.2
Haimovitz-Friedman, A.3
Martin, S.4
Green, D.5
McLoughlin, M.6
Cordon-Cardo, C.7
Schuchman, E.H.8
Fuks, Z.9
Kolesnick, R.10
-
155
-
-
0032032270
-
Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3
-
155. AMARANTE-MENDES GP, NAEKYUNG KIM C, LIU L, HUANG Y, PERKINS CL, GREEN DR, BHALLA K: Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3. Blood 91:1700-1705, 1998
-
(1998)
Blood
, vol.91
, pp. 1700-1705
-
-
Amarante-Mendes, G.P.1
Naekyung Kim, C.2
Liu, L.3
Huang, Y.4
Perkins, C.L.5
Green, D.R.6
Bhalla, K.7
-
156
-
-
0032900335
-
Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis
-
156. TEPPER AD, DE VRIES E, VAN BLITTERSWIJK WJ, BORST J: Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis. J Clin Invest 103:971-978, 1999
-
(1999)
J Clin Invest
, vol.103
, pp. 971-978
-
-
Tepper, A.D.1
De Vries, E.2
Van Blitterswijk, W.J.3
Borst, J.4
-
157
-
-
0002842390
-
Alpha-galactosidase A deficiency: Fabry disease
-
New York, McGraw-Hill
-
157. DESNICK RJ, IOANNOU YA, ENG CM: Alpha-galactosidase A deficiency: Fabry disease, in The Metabolic and Molecular Bases of Inherited Disease (7th ed), New York, McGraw-Hill, pp 2741-2784, 1995
-
(1995)
The Metabolic and Molecular Bases of Inherited Disease (7th Ed)
, pp. 2741-2784
-
-
Desnick, R.J.1
Ioannou, Y.A.2
Eng, C.M.3
-
158
-
-
0027263071
-
Gaucher disease as a paradigm of current issues regarding single gene mutations of humans
-
158. BEUTLER E: Gaucher disease as a paradigm of current issues regarding single gene mutations of humans. Proc Natl Acad Sci USA 90:5384-5390, 1993
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 5384-5390
-
-
Beutler, E.1
-
159
-
-
12944265457
-
Infusion of alpha-galactosidase A reduces tissue globotriaosyceramide storage in patients with Fabry disease
-
159. SCHIFFMANN R, MURRAY GJ, TRECO D, DANIEL P, SELLOS-MOURA M, QUIRK JM, ZTRZOW GC, BOROWSKI M, LOVEDAY K, ANDERSON T, GILLESPIE F, OLIVER KL, JEFFRIES NO, DOO E, LIANG TJ, KREPS C, GUNTER K, FREI K, CRUTCHFTELD K, SELDEN RF, BRADY RO: Infusion of alpha-galactosidase A reduces tissue globotriaosyceramide storage in patients with Fabry disease. Proc Natl Acad Sci USA 97:365-370, 2000
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 365-370
-
-
Schiffmann, R.1
Murray, G.J.2
Treco, D.3
Daniel, P.4
Sellos-Moura, M.5
Quirk, J.M.6
Ztrzow, G.C.7
Borowski, M.8
Loveday, K.9
Anderson, T.10
Gillespie, F.11
Oliver, K.L.12
Jeffries, N.O.13
Doo, E.14
Liang, T.J.15
Kreps, C.16
Gunter, K.17
Frei, K.18
Crutchfteld, K.19
Selden, R.F.20
Brady, R.O.21
more..
-
160
-
-
0029939988
-
Treatment of Gaucher disease with an enzyme inhibitor
-
160. RADIN NS: Treatment of Gaucher disease with an enzyme inhibitor. Glycoconj J 13:153-157, 1996
-
(1996)
Glycoconj J
, vol.13
, pp. 153-157
-
-
Radin, N.S.1
-
161
-
-
0033557199
-
A genetic model of substrate deprivation therapy for a glycosphingolipid storage disorder
-
161. LIU Y, WADA R, KAWAI H, SANGO K, DENG C, TAI T, MCDONALD MP, ARAUJO K, CRAWLEY JN, BIERFREUND U, SANDHOFF K, SUZUKI K, PROIA RL: A genetic model of substrate deprivation therapy for a glycosphingolipid storage disorder. J Clin Invest 103:497-505, 1999
-
(1999)
J Clin Invest
, vol.103
, pp. 497-505
-
-
Liu, Y.1
Wada, R.2
Kawai, H.3
Sango, K.4
Deng, C.5
Tai, T.6
McDonald, M.P.7
Araujo, K.8
Crawley, J.N.9
Bierfreund, U.10
Sandhoff, K.11
Suzuki, K.12
Proia, R.L.13
-
162
-
-
0030937840
-
Prevention of lysosomal storage in Tay-Sachs mice treated with N-butyldeoxynojirimycin
-
162. PLATT FM, NEISES GR, REINKENSMEIER G, TOWNSEND MJ, PERRY VH, PROIA RL, WINCHESTER B, DWEK RA, BUTTERS TD: Prevention of lysosomal storage in Tay-Sachs mice treated with N-butyldeoxynojirimycin. Science 276:428-431, 1997
-
(1997)
Science
, vol.276
, pp. 428-431
-
-
Platt, F.M.1
Neises, G.R.2
Reinkensmeier, G.3
Townsend, M.J.4
Perry, V.H.5
Proia, R.L.6
Winchester, B.7
Dwek, R.A.8
Butters, T.D.9
-
163
-
-
0033060380
-
Delayed symptom onset and increased life expectancy in Sandhoff disease mice treated with N-butyldeoxynojirimycin
-
163. JEYAKUMAR M, BUTTERS TD, CORTINA-BORJA M, HUNNAM V, PROIA RL, PERRY VH, DWEK RA, PLATT FM: Delayed symptom onset and increased life expectancy in Sandhoff disease mice treated with N-butyldeoxynojirimycin. Proc Natl Acad Sci USA 96:6388-6393, 1999
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6388-6393
-
-
Jeyakumar, M.1
Butters, T.D.2
Cortina-Borja, M.3
Hunnam, V.4
Proia, R.L.5
Perry, V.H.6
Dwek, R.A.7
Platt, F.M.8
-
164
-
-
0033930125
-
Glycosphingolipid depletion in Fabry disease lymphoblasts with potent inhibitors of glucosylceramide synthase
-
164. ABE A, AREND LJ, LEE L, LINGWOOD C, BRADY RO, SHAYMAN JA: Glycosphingolipid depletion in Fabry disease lymphoblasts with potent inhibitors of glucosylceramide synthase. Kidney Int 57:446-454, 2000
-
(2000)
Kidney Int
, vol.57
, pp. 446-454
-
-
Abe, A.1
Arend, L.J.2
Lee, L.3
Lingwood, C.4
Brady, R.O.5
Shayman, J.A.6
-
165
-
-
0021946215
-
The association between isopathic hemolytic uremic syndrome and infection by verotoxin-producing Escherichia coli
-
165. KARMALI MA, PETRIC M, LIM C, FLEMING PC, ARBUS GS, LIOR H: The association between isopathic hemolytic uremic syndrome and infection by verotoxin-producing Escherichia coli. J Infect Dis 151:775-782, 1985
-
(1985)
J Infect Dis
, vol.151
, pp. 775-782
-
-
Karmali, M.A.1
Petric, M.2
Lim, C.3
Fleming, P.C.4
Arbus, G.S.5
Lior, H.6
-
166
-
-
0030113327
-
Two distinct binding sites for globotriaosyl ceramide on verotoxins: Identification by molecular modelling and confirmation using deoxy analogues and a new glycolipid receptor for all verotoxins
-
166. NYHOLM PG, MAGNUSSON G, ZHENG Z, NOREL R, BINNINGTONBOYD B, LINGWOOD CA: Two distinct binding sites for globotriaosyl ceramide on verotoxins: Identification by molecular modelling and confirmation using deoxy analogues and a new glycolipid receptor for all verotoxins. Chem Biol 3:263-275, 1996
-
(1996)
Chem Biol
, vol.3
, pp. 263-275
-
-
Nyholm, P.G.1
Magnusson, G.2
Zheng, Z.3
Norel, R.4
Binningtonboyd, B.5
Lingwood, C.A.6
-
167
-
-
0026454927
-
Tumor necrosis factor and interleukin-1 induce expression of the verocytotoxin receptor globotriaosylceramide on human endothelial cells: Implications for the pathogenesis of the hemolytic uremic syndrome
-
167. VAN DE KAR NC, MONNENS LA, KARMALI MA, VAN HINSBERGH VW: Tumor necrosis factor and interleukin-1 induce expression of the verocytotoxin receptor globotriaosylceramide on human endothelial cells: Implications for the pathogenesis of the hemolytic uremic syndrome. Blood 80:2755-2764, 1992
-
(1992)
Blood
, vol.80
, pp. 2755-2764
-
-
Van De Kar, N.C.1
Monnens, L.A.2
Karmali, M.A.3
Van Hinsbergh, V.W.4
-
168
-
-
0021688561
-
Enzymatic and organizational difference in expression of a burkitt lymphoma-associated antigen (globotriaosylceramide) in burkitt lymphoma and lymphoblastoid lines
-
168. WIELS J, HOLMES EH, COCHRAN N, TURSZ T, HAKOMORI S: Enzymatic and organizational difference in expression of a Burkitt lymphoma-associated antigen (globotriaosylceramide) in Burkitt lymphoma and lymphoblastoid lines. J Biol Chem 259:14783-14787, 1984
-
(1984)
J Biol Chem
, vol.259
, pp. 14783-14787
-
-
Wiels, J.1
Holmes, E.H.2
Cochran, N.3
Tursz, T.4
Hakomori, S.5
-
169
-
-
0026007043
-
HIV-associated nephropathy in transgenic mice expressing HIV-1 genes
-
169. DICKIE P, FELSER J, ECKHAUS M, BRYANT J, SILVER J, MARINOS N, NOTKINS AL: HIV-associated nephropathy in transgenic mice expressing HIV-1 genes. Virology 185:109-119, 1991
-
(1991)
Virology
, vol.185
, pp. 109-119
-
-
Dickie, P.1
Felser, J.2
Eckhaus, M.3
Bryant, J.4
Silver, J.5
Marinos, N.6
Notkins, A.L.7
-
171
-
-
0033607256
-
Calcium-independent activation of endothelial nitric oxide synthase by ceramide
-
171. IGARASHI J, THATTE HS, PRABHAKAR P, GOLAN DE, MICHEL T: Calcium-independent activation of endothelial nitric oxide synthase by ceramide. Proc Natl Acad Sci USA 96:12583-12588, 1999
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12583-12588
-
-
Igarashi, J.1
Thatte, H.S.2
Prabhakar, P.3
Golan, D.E.4
Michel, T.5
-
172
-
-
0031781921
-
Ceramide accumulation during oxidant renal tubular injury: Mechanisms and potential consequences
-
172. ZAGER RA, CONRAD DS, BURKHART K: Ceramide accumulation during oxidant renal tubular injury: Mechanisms and potential consequences. J Am Soc Nephrol 9:1670-1680, 1998
-
(1998)
J Am Soc Nephrol
, vol.9
, pp. 1670-1680
-
-
Zager, R.A.1
Conrad, D.S.2
Burkhart, K.3
-
173
-
-
0031848460
-
Role of enhanced ceramide generation in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells
-
173. UEDA N, KAUSHAL GP, HONG X, SHAH SV: Role of enhanced ceramide generation in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells. Kidney Int 2:399-406, 1998
-
(1998)
Kidney Int
, vol.2
, pp. 399-406
-
-
Ueda, N.1
Kaushal, G.P.2
Hong, X.3
Shah, S.V.4
|