Designing anticancer drugs via the achilles heel: Ceramide, allylic ketones, and mitochondria

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 7, 2003, Pages 1511-1529

  Radin, Norman S ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; ALCOHOL; ANTHRACYCLINE; ANTINEOPLASTIC AGENT; CALCITRIOL; CAMPTOTHECIN; CERAMIDE; CIPROFLOXACIN; CROTONYLOXYMETHYL TRIHYDROXYCYCLOHEXENONE; CURCUMIN; DOCETAXEL; FLAVOPIRIDOL; GLUCOCORTICOID; HYDROXYL GROUP; ILLUDIN M; KETONE; KETONE DERIVATIVE; MI 10079; MI 1743; MI 2337; MI 2703; MI 4122; MI 4923; MI 6238; MI 8190; MI 9271; MI 9283; MITOXANTRONE; NITROGEN; PACLITAXEL; RALOXIFENE; REACTIVE OXYGEN METABOLITE; SPHINGOLIPID; TETRACYCLINE; TETRAHYDROCANNABINOL; UNCLASSIFIED DRUG; ANTHRACYCLINE DERIVATIVE; ANTIBIOTIC AGENT; COLCHICINE; CYTARABINE; DEXAMETHASONE; DOXORUBICIN; DOXYCYCLINE; GLUTATHIONE; ILLUDIN S; LIPID; MI 1009; MI 2813; MI 2960; MI 3431; MI 3473; MI 3474; MI 7052; MITOMYCIN C; UNINDEXED DRUG; VINBLASTINE;

ARTICLE; ATOM; CANCER CELL; CHEMOTHERAPY; HEEL; MITOCHONDRION; TUMOR; ACHILLES TENDON; ANTINEOPLASTIC ACTIVITY; BLADDER CANCER; BREAST CANCER; CANCER THERAPY; CARDIOTOXICITY; CELL STIMULATION; CHEMICAL BOND; COLON CANCER; COLON TUMOR; DRUG ACTIVITY; DRUG DESIGN; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; HUMAN; LUNG CANCER; NONHUMAN; PANCREAS CANCER; PROSTATE CANCER; REVIEW; SKIN CANCER; TUMOR CELL;

EID: 0037375586     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(03)00062-2     Document Type: Article

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