Glucosylceramide synthase inhibition enhances vincristine-induced cytotoxicity

International Journal of Cancer

Volumn 93, Issue 1, 2001, Pages 131-138

  Olshefski, Randal S ^a,b   Ladisch, Stephan ^a,b  

^a CHILDREN S RESEARCH INSTITUTE   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Cell cycle arrest; Ceramide; Drug resistance; Glucosylceramide synthase inhibition; Programmed cell death

Indexed keywords

CERAMIDE; CERAMIDE GLUCOSYLTRANSFERASE; PYRROLIDINE DERIVATIVE; SPHINGOLIPID; VINCRISTINE;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL LEVEL; CELL PROLIFERATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LIPID METABOLISM; LIPOGENESIS; MITOSIS INHIBITION; MODULATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL CYCLE; CELL SURVIVAL; DRUG RESISTANCE, MULTIPLE; ENZYME INHIBITORS; GLUCOSYLTRANSFERASES; HUMANS; LEUKEMIA, T-CELL; P-GLYCOPROTEIN; PROPANOLAMINES; PYRROLIDINES; SPHINGOLIPIDS; TUMOR CELLS, CULTURED; VINCRISTINE;

EID: 0035399826     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.1301     Document Type: Article

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