-
3
-
-
0034483954
-
Early transitory rise in intracellular pH leads to Bax conformation change during ceramide-induced apoptosis
-
(2000)
Apoptosis
, vol.5
, pp. 551-560
-
-
Belaud-Rotureau, M.A.1
Leducq, N.2
Macouillard Poulletier de Gannes, F.3
Diolez, P.4
Lacoste, L.5
Lacombe, F.6
Bernard, P.7
Belloc, F.8
-
8
-
-
0028095477
-
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase
-
(1994)
J Exp Med
, vol.180
, pp. 1547-1552
-
-
Cifone, M.G.1
De Maria, R.2
Roncaioli, P.3
Rippo, M.R.4
Azuma, M.5
Laniers, L.L.6
Santoni, A.7
Jesti, R.8
-
10
-
-
0034117177
-
Mitochondria-nuclear translocation of A1F in apoptosis and necrosis
-
(2000)
FASEB J
, vol.5
, pp. 729-739
-
-
Daugas, E.1
Susin, S.A.2
Zamzami, N.3
Ferri, K.F.4
Irinopoulou, T.5
Larochette, N.6
Prevost, M.C.7
Leber, B.8
Andrews, D.9
Penninger, J.10
Kroemer, G.11
-
13
-
-
0033535350
-
Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
-
(1999)
J Cell Biol
, vol.144
, pp. 891-901
-
-
Desagher, S.1
Osen-Sand, A.2
Nichols, A.3
Eskes, R.4
Montessuit, S.5
Lauper, S.6
Maundrell, K.7
Antonsson, B.8
Martinou, J.C.9
-
22
-
-
0014027942
-
Enzymatic hydrolysis of sphingolipids
-
(1996)
J Biol Chem
, vol.241
, pp. 3724-3730
-
-
Gatt, S.1
-
24
-
-
0032487582
-
Regulated targeting of BAX to mitochondria
-
(1998)
J Cell Biol
, vol.143
, pp. 207-215
-
-
Goping, I.S.1
Gross, A.2
Lavoie, J.N.3
Nguyen, M.4
Jemmerson, R.5
Roth, K.6
Korsmeyer, S.J.7
Shore, G.C.8
-
29
-
-
0030448021
-
Functions of ceramide in coordinating cellular responses to stress
-
(1996)
Science
, vol.274
, pp. 1855-1859
-
-
Hannun, Y.A.1
-
32
-
-
0024439904
-
Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities
-
(1989)
Biochemistry
, vol.28
, pp. 6796-6800
-
-
Igarashi, Y.1
Hakomori, S.2
Toyokuni, T.3
Dean, B.4
Fujita, S.5
Sugimoto, M.6
Ogawa, T.7
El-Ghendy, K.8
Racker, E.9
-
37
-
-
0034614658
-
Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage
-
(2000)
J Biol Chem
, vol.275
, pp. 322-327
-
-
Kharbanda, S.1
Saxena, S.2
Yoshida, K.3
Pandey, P.4
Kaneki, M.5
Wang, O.6
Cheng, K.7
Chen, Y.N.8
Campbell, A.9
Sudha, T.10
Yuan, Z.M.11
Narula, J.12
Weichselbaum, R.13
Nalin, C.14
Kufe, D.15
-
39
-
-
0030479325
-
Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification of the first molecular lesion causing Farber disease
-
(1996)
J Biol Chem
, vol.271
, pp. 33110-33115
-
-
Koch, J.1
Gartner, S.2
Li, C.M.3
Quintern, L.E.4
Bernardo, K.5
Levran, O.6
Schnabel, D.7
Desnick, R.J.8
Schuchman, E.H.9
Sandhoff, K.10
-
42
-
-
0031019309
-
Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells
-
(1997)
J Biol Chem
, vol.272
, pp. 1682-1687
-
-
Lavie, Y.1
Cao, H.T.2
Volner, A.3
Lucci, A.4
Han, T.Y.5
Geffen, V.6
Giuliano, A.E.7
Cabot, M.C.8
-
45
-
-
0033615537
-
Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate
-
(1999)
Cell
, vol.99
, pp. 301-312
-
-
Lee, M.J.1
Thangada, S.2
Claffey, K.P.3
Ancellin, N.4
Liu, C.H.5
Kluk, M.6
Volpi, M.7
Sha'afi, R.I.8
Hla, T.9
-
47
-
-
0034682890
-
Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3
-
(2000)
Science
, vol.289
, pp. 1159-1164
-
-
Li, H.1
Kolluri, S.K.2
Gu, J.3
Dawson, M.I.4
Cao, X.5
Hobbs, P.D.6
Lin, B.7
Chen, G.8
Lu, J.9
Lin, F.10
Xie, Z.11
Fontana, J.A.12
Reed, J.C.13
Zhang, X.14
-
48
-
-
0034640102
-
Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis
-
(2000)
Cell
, vol.101
, pp. 389-399
-
-
Li, K.1
Li, Y.2
Shelton, J.M.3
Richardson, J.A.4
Spencer, E.5
Chen, Z.J.6
Wang, X.7
Williams, R.S.8
-
49
-
-
0030715323
-
Cytochrome c, dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
51
-
-
0033581014
-
Ataxia telangiectasia-mutated gene product inhibits DNA damage-induced apoptosis via ceramide synthase
-
(1999)
J Biol Chem
, vol.274
, pp. 17908-17917
-
-
Liao, W.C.1
Haimovitz-Friedman, A.2
Persaud, R.S.3
McLoughlin, M.4
Ehleiter, D.5
Zhang, N.6
Gatei, M.7
Lavin, M.8
Kolesnick, R.9
Fuks, Z.10
-
56
-
-
0034698182
-
Mitochondrial translocation of protein kinase C delta in phorhol ester-induced cytochrome c release and apoptosis
-
(2000)
J Biol Chem
, vol.275
, pp. 21793-21796
-
-
Majumder, P.K.1
Pandey, P.2
Sun, X.3
Cheng, K.4
Datta, R.5
Saxena, S.6
Kharbanda, S.7
Kufe, D.8
-
65
-
-
0034640281
-
Noxa, aBH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
68
-
-
0029014350
-
Acid sphingomyelinase-deficient mice mimic the neurovisceral form of human lysosomal storage disease (Niemann-Pick disease)
-
(1995)
Cell
, vol.81
, pp. 1053-1061
-
-
Otterbach, B.1
Stoffel, W.2
-
69
-
-
0033883377
-
The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells
-
(2000)
Am J Pathol
, vol.157
, pp. 449-461
-
-
O'Reilly, L.A.1
Cullen, L.2
Visvader, J.3
Lindeman, G.J.4
Print, C.5
Bath, M.L.6
Huang, D.C.7
Strasser, A.8
-
72
-
-
0028934898
-
Stereoselectivity of induction of the retinoblastoma gene product (pRb) dephosphorylation by D-erythro-sphingosine supports a role for pRb in growth suppression by sphingosine
-
(1995)
Biochemistry
, vol.34
, pp. 1885-1892
-
-
Pushkareva, M.1
Chao, R.2
Bielawska, A.3
Merrill A.H., Jr.4
Crane, H.M.5
Lagu, B.6
Liotta, D.7
Hannun, Y.A.8
-
73
-
-
0029889045
-
Sphingomyelin-derived lipids differentially regulate the extracellular signal-regulated kinase 2 (ERK-2) and c-Jun N-terminal kinase (JNK) signal cascades in airway smooth muscle
-
(1996)
Eur J Biochem
, vol.237
, pp. 819-826
-
-
Pyne, S.1
Chapman, J.2
Steele, L.3
Pyne, N.J.4
-
75
-
-
0029912997
-
The differential regulation of cyclic AMP by sphingomyelin-derived lipids and the modulation of sphingolipid-stimulated extracellular signal regulated kinase-2 in airway smooth muscle
-
(1996)
Biochem J
, vol.315
, pp. 917-923
-
-
Pyne, S.1
Pyne, N.J.2
-
78
-
-
0029834974
-
c-Jun is a downstream target for ceramide-activated protein phosphatase in A431 cells
-
(1996)
J Biol Chem
, vol.271
, pp. 21375-21380
-
-
Reyes, J.G.1
Robayna, I.G.2
Delgado, P.S.3
Gonzalez, I.H.4
Aguiar, J.Q.5
Rosas, F.E.6
Fanjul, L.F.7
Galarreta, C.M.8
-
82
-
-
0024412757
-
Different effects of sphingosine, R59022 and anionic amphiphiles on two diacylglycerol kinase isozymes purified from porcine thymus cytosol
-
(1989)
FEBS Lett
, vol.255
, pp. 409-413
-
-
Sakane, F.1
Yamada, K.2
Kanoh, H.3
-
84
-
-
16044364385
-
Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis
-
(1996)
Cell
, vol.86
, pp. 189-199
-
-
Santana, P.1
Pena, L.A.2
Haimovitz-Friedman, A.3
Martin, S.4
Green, D.5
McLoughlin, M.6
Cordon-Cardo, C.7
Schuchman, E.H.8
Fuks, Z.9
Kolesnick, R.10
-
87
-
-
0034681110
-
Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity
-
(2000)
PNAS
, vol.97
, pp. 577-582
-
-
Shimizu, S.1
Tsujimoto, Y.2
-
93
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
Mangion, J.7
Jacotot, E.8
Costantini, P.9
Loeffler, M.10
Larochette, M.11
Goodlett, D.R.12
Aebersold, R.13
Siderovski, D.P.14
Penninger, J.M.15
Kroemer, G.16
-
98
-
-
0034607702
-
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
-
(2000)
Science
, vol.288
, pp. 870-874
-
-
Tournier, C.1
Hess, P.2
Yang, D.D.3
Xu, J.4
Turner, T.K.5
Nimnual, A.6
Bar-Sagi, D.7
Jones, S.N.8
Flavell, R.A.9
Davis, R.J.10
-
99
-
-
0033537768
-
2+-induced apoptosis through calcineurin dephosphorylation of BAD
-
(1999)
Science
, vol.284
, pp. 339-343
-
-
Wang, H.G.1
Pathan, N.2
Ethell, I.M.3
Krajewski, S.4
Yamaguchi, Y.5
Shibasaki, F.6
McKeon, F.7
Bobo, T.8
Franke, T.F.9
Reed, J.C.10
-
100
-
-
0034663829
-
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c
-
(2000)
Genes Dev
, vol.14
, pp. 2060-2071
-
-
Wei, M.C.1
Lindsten, T.2
Mootha, V.K.3
Weiler, S.4
Gross, A.5
Ashiya, M.6
Thompson, C.B.7
Korsmeyer, S.J.8
-
102
-
-
0032568836
-
Involvement of de novo ceramide biosynthesis in tumor necrosis factor-a cycloheximide-induced cerebral endothelial cell death
-
(1998)
J Biol Chem
, vol.273
, pp. 16521-16526
-
-
Xu, J.1
Yeh, C.H.2
Chen, S.3
He, L.4
Sensi, S.L.5
Canzoniero, L.M.6
Choi, D.W.7
Hsu, C.Y.8
-
105
-
-
0026049696
-
Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation
-
(1991)
J Cell Biol
, vol.114
, pp. 155-167
-
-
Zhang, H.1
Desai, N.N.2
Olivera, A.3
Seki, T.4
Brooke, G.5
Spiegel, S.6
-
107
-
-
0343742670
-
Kinase suppressor of Ras is ceramide-activated protein kinase
-
(1997)
Cell
, vol.89
, pp. 63-72
-
-
Zhang, Y.1
Yao, B.2
Delikat, S.3
Bayoumy, S.4
Lin, X.H.5
Basu, S.6
McGinley, M.7
Chan-Hui, P.Y.8
Lichenstein, H.9
Kolesnick, R.10
|