-
1
-
-
79955541353
-
Strength of TCR-peptide/MHC interactions and in vivo T cell responses
-
Corse E., et al. Strength of TCR-peptide/MHC interactions and in vivo T cell responses. J. Immunol. 2011, 186:5039-5045.
-
(2011)
J. Immunol.
, vol.186
, pp. 5039-5045
-
-
Corse, E.1
-
2
-
-
0033615678
-
A direct estimate of the human alphabeta T cell receptor diversity
-
Arstila T.P., et al. A direct estimate of the human alphabeta T cell receptor diversity. Science 1999, 286:958-961.
-
(1999)
Science
, vol.286
, pp. 958-961
-
-
Arstila, T.P.1
-
3
-
-
77956460339
-
Overlap and effective size of the human CD8+ T cell receptor repertoire
-
Robins H.S., et al. Overlap and effective size of the human CD8+ T cell receptor repertoire. Sci. Transl. Med. 2010, 2:47ra64.
-
(2010)
Sci. Transl. Med.
, vol.2
, pp. 47ra64
-
-
Robins, H.S.1
-
4
-
-
77952316386
-
On the composition of the preimmune repertoire of T cells specific for peptide-major histocompatibility complex ligands
-
Jenkins M.K., et al. On the composition of the preimmune repertoire of T cells specific for peptide-major histocompatibility complex ligands. Annu. Rev. Immunol. 2010, 28:275-294.
-
(2010)
Annu. Rev. Immunol.
, vol.28
, pp. 275-294
-
-
Jenkins, M.K.1
-
5
-
-
0023720148
-
T-cell antigen receptor genes and T-cell recognition
-
Davis M.M., Bjorkman P.J. T-cell antigen receptor genes and T-cell recognition. Nature 1988, 334:395-402.
-
(1988)
Nature
, vol.334
, pp. 395-402
-
-
Davis, M.M.1
Bjorkman, P.J.2
-
6
-
-
22744441535
-
How the T cell repertoire becomes peptide and MHC specific
-
Huseby E.S., et al. How the T cell repertoire becomes peptide and MHC specific. Cell 2005, 122:247-260.
-
(2005)
Cell
, vol.122
, pp. 247-260
-
-
Huseby, E.S.1
-
7
-
-
33750113432
-
Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide
-
Huseby E.S., et al. Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide. Nat. Immunol. 2006, 7:1191-1199.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1191-1199
-
-
Huseby, E.S.1
-
8
-
-
81955161800
-
A role for differential variable gene pairing in creating T cell receptors specific for unique major histocompatibility ligands
-
Stadinski B.D., et al. A role for differential variable gene pairing in creating T cell receptors specific for unique major histocompatibility ligands. Immunity 2011, 35:694-704.
-
(2011)
Immunity
, vol.35
, pp. 694-704
-
-
Stadinski, B.D.1
-
9
-
-
84902204273
-
Effect of CDR3 sequences and distal V gene residues in regulating TCR-MHC contacts and ligand specificity
-
Stadinski B.D., et al. Effect of CDR3 sequences and distal V gene residues in regulating TCR-MHC contacts and ligand specificity. J. Immunol. 2014, 192:6071-6082.
-
(2014)
J. Immunol.
, vol.192
, pp. 6071-6082
-
-
Stadinski, B.D.1
-
10
-
-
13944262009
-
The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition
-
Borg N.A., et al. The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition. Nat. Immunol. 2005, 6:171-180.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 171-180
-
-
Borg, N.A.1
-
11
-
-
84901295133
-
Deconstructing the peptide-MHC specificity of T cell recognition
-
Birnbaum M.E., et al. Deconstructing the peptide-MHC specificity of T cell recognition. Cell 2014, 157:1073-1087.
-
(2014)
Cell
, vol.157
, pp. 1073-1087
-
-
Birnbaum, M.E.1
-
12
-
-
84907308588
-
Revisiting thymic positive selection and the mature T cell repertoire for antigen
-
Vrisekoop N., et al. Revisiting thymic positive selection and the mature T cell repertoire for antigen. Immunity 2014, 41:181-190.
-
(2014)
Immunity
, vol.41
, pp. 181-190
-
-
Vrisekoop, N.1
-
13
-
-
84921278229
-
T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity
-
Nelson R.W., et al. T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity. Immunity 2015, 42:95-107.
-
(2015)
Immunity
, vol.42
, pp. 95-107
-
-
Nelson, R.W.1
-
14
-
-
84927652023
-
Dynamic tuning of lymphocytes: physiological basis, mechanisms, and function
-
Grossman Z., Paul W.E. Dynamic tuning of lymphocytes: physiological basis, mechanisms, and function. Annu. Rev. Immunol. 2015, 33:677-713.
-
(2015)
Annu. Rev. Immunol.
, vol.33
, pp. 677-713
-
-
Grossman, Z.1
Paul, W.E.2
-
15
-
-
0029063148
-
Kinetic proofreading in T-cell receptor signal transduction
-
McKeithan T.W. Kinetic proofreading in T-cell receptor signal transduction. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:5042-5046.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 5042-5046
-
-
McKeithan, T.W.1
-
16
-
-
84906559162
-
Phenotypic models of T cell activation
-
Lever M., et al. Phenotypic models of T cell activation. Nat. Rev. Immunol. 2014, 14:619-629.
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 619-629
-
-
Lever, M.1
-
17
-
-
84906241799
-
Insights into the initiation of TCR signaling
-
Chakraborty A.K., Weiss A. Insights into the initiation of TCR signaling. Nat. Immunol. 2014, 15:798-807.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 798-807
-
-
Chakraborty, A.K.1
Weiss, A.2
-
18
-
-
84867406200
-
TCR signaling emerges from the sum of many parts
-
Kuhns M.S., Davis M.M. TCR signaling emerges from the sum of many parts. Front. Immunol. 2012, 3:159.
-
(2012)
Front. Immunol.
, vol.3
, pp. 159
-
-
Kuhns, M.S.1
Davis, M.M.2
-
19
-
-
84915754505
-
Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance
-
Stepanek O., et al. Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance. Cell 2014, 159:333-345.
-
(2014)
Cell
, vol.159
, pp. 333-345
-
-
Stepanek, O.1
-
20
-
-
84930823744
-
Mechanisms of T-lymphocyte signaling and activation
-
Lippincott Williams & Wilkins, W.H. Paul Series (Ed.)
-
Saito T. Mechanisms of T-lymphocyte signaling and activation. Fundamental Immunology 2013, 306-324. Lippincott Williams & Wilkins. 7th edn. W.H. Paul Series (Ed.).
-
(2013)
Fundamental Immunology
, pp. 306-324
-
-
Saito, T.1
-
21
-
-
84859891065
-
Protein tyrosine phosphatases in lymphocyte activation and autoimmunity
-
Rhee I., Veillette A. Protein tyrosine phosphatases in lymphocyte activation and autoimmunity. Nat. Immunol. 2012, 13:439-447.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 439-447
-
-
Rhee, I.1
Veillette, A.2
-
22
-
-
27844541328
-
Modeling T cell antigen discrimination based on feedback control of digital ERK responses
-
Altan-Bonnet G., Germain R.N. Modeling T cell antigen discrimination based on feedback control of digital ERK responses. PLoS Biol. 2005, 3:e356.
-
(2005)
PLoS Biol.
, vol.3
, pp. e356
-
-
Altan-Bonnet, G.1
Germain, R.N.2
-
23
-
-
0037338890
-
TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways
-
Stefanova I., et al. TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways. Nat. Immunol. 2003, 4:248-254.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 248-254
-
-
Stefanova, I.1
-
24
-
-
84922257832
-
A THEMIS:SHP1 complex promotes T-cell survival
-
Paster W., et al. A THEMIS:SHP1 complex promotes T-cell survival. EMBO J. 2015, 34:393-409.
-
(2015)
EMBO J.
, vol.34
, pp. 393-409
-
-
Paster, W.1
-
25
-
-
0030176270
-
Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response
-
Sykulev Y., et al. Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response. Immunity 1996, 4:565-571.
-
(1996)
Immunity
, vol.4
, pp. 565-571
-
-
Sykulev, Y.1
-
26
-
-
0037167816
-
Direct observation of ligand recognition by T cells
-
Irvine D.J., et al. Direct observation of ligand recognition by T cells. Nature 2002, 419:845-849.
-
(2002)
Nature
, vol.419
, pp. 845-849
-
-
Irvine, D.J.1
-
27
-
-
0025095655
-
Ligand thresholds at different stages of T cell development
-
Yagi J., Janeway C.A. Ligand thresholds at different stages of T cell development. Int. Immunol. 1990, 2:83-89.
-
(1990)
Int. Immunol.
, vol.2
, pp. 83-89
-
-
Yagi, J.1
Janeway, C.A.2
-
28
-
-
0025761241
-
Lower receptor avidity required for thymic clonal deletion than for effector T-cell function
-
Pircher H., et al. Lower receptor avidity required for thymic clonal deletion than for effector T-cell function. Nature 1991, 351:482-485.
-
(1991)
Nature
, vol.351
, pp. 482-485
-
-
Pircher, H.1
-
29
-
-
0032538986
-
Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells
-
Davey G.M., et al. Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells. J. Exp. Med. 1998, 188:1867-1874.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1867-1874
-
-
Davey, G.M.1
-
30
-
-
0033103008
-
Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire
-
Lucas B., et al. Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire. Immunity 1999, 10:367-376.
-
(1999)
Immunity
, vol.10
, pp. 367-376
-
-
Lucas, B.1
-
31
-
-
84906243997
-
The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function
-
Hogquist K.A., Jameson S.C. The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function. Nat. Immunol. 2014, 15:815-823.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 815-823
-
-
Hogquist, K.A.1
Jameson, S.C.2
-
32
-
-
0030014002
-
T-cell-receptor affinity and thymocyte positive selection
-
Alam S.M., et al. T-cell-receptor affinity and thymocyte positive selection. Nature 1996, 381:616-620.
-
(1996)
Nature
, vol.381
, pp. 616-620
-
-
Alam, S.M.1
-
33
-
-
84915747866
-
Optimal T-cell receptor affinity for inducing autoimmunity
-
Koehli S., et al. Optimal T-cell receptor affinity for inducing autoimmunity. Proc. Natl. Acad. Sci. U.S.A. 2014, 111:17248-17253.
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 17248-17253
-
-
Koehli, S.1
-
34
-
-
0035041538
-
Age-dependent T cell tolerance and autoimmunity to myelin basic protein
-
Huseby E.S., et al. Age-dependent T cell tolerance and autoimmunity to myelin basic protein. Immunity 2001, 14:471-481.
-
(2001)
Immunity
, vol.14
, pp. 471-481
-
-
Huseby, E.S.1
-
35
-
-
33947721625
-
MiR-181a is an intrinsic modulator of T cell sensitivity and selection
-
Li Q.J., et al. miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 2007, 129:147-161.
-
(2007)
Cell
, vol.129
, pp. 147-161
-
-
Li, Q.J.1
-
36
-
-
70350435670
-
An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a
-
Ebert P.J., et al. An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a. Nat. Immunol. 2009, 10:1162-1169.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 1162-1169
-
-
Ebert, P.J.1
-
37
-
-
84878203252
-
The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis
-
Henao-Mejia J., et al. The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis. Immunity 2013, 38:984-997.
-
(2013)
Immunity
, vol.38
, pp. 984-997
-
-
Henao-Mejia, J.1
-
38
-
-
18844473151
-
PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes
-
Sun Z., et al. PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes. Nature 2000, 404:402-407.
-
(2000)
Nature
, vol.404
, pp. 402-407
-
-
Sun, Z.1
-
39
-
-
0038375851
-
Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation
-
Egawa T., et al. Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation. Curr. Biol. 2003, 13:1252-1258.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1252-1258
-
-
Egawa, T.1
-
40
-
-
17744386318
-
Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure
-
Ruland J., et al. Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure. Cell 2001, 104:33-42.
-
(2001)
Cell
, vol.104
, pp. 33-42
-
-
Ruland, J.1
-
41
-
-
0345358541
-
Differential requirement for Malt1 in T and B cell antigen receptor signaling
-
Ruland J., et al. Differential requirement for Malt1 in T and B cell antigen receptor signaling. Immunity 2003, 19:749-758.
-
(2003)
Immunity
, vol.19
, pp. 749-758
-
-
Ruland, J.1
-
42
-
-
84890561320
-
Themis sets the signal threshold for positive and negative selection in T-cell development
-
Fu G., et al. Themis sets the signal threshold for positive and negative selection in T-cell development. Nature 2013, 504:441-445.
-
(2013)
Nature
, vol.504
, pp. 441-445
-
-
Fu, G.1
-
43
-
-
67651154100
-
Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling
-
Fu G., et al. Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling. Nat. Immunol. 2009, 10:848-856.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 848-856
-
-
Fu, G.1
-
44
-
-
67651166585
-
Themis, a T cell-specific protein important for late thymocyte development
-
Lesourne R., et al. Themis, a T cell-specific protein important for late thymocyte development. Nat. Immunol. 2009, 10:840-847.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 840-847
-
-
Lesourne, R.1
-
45
-
-
67651149464
-
Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection
-
Johnson A.L., et al. Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection. Nat. Immunol. 2009, 10:831-839.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 831-839
-
-
Johnson, A.L.1
-
46
-
-
84861235503
-
Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling
-
Wang D., et al. Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling. Nat. Immunol. 2012, 13:560-568.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 560-568
-
-
Wang, D.1
-
47
-
-
84865439555
-
A voltage-gated sodium channel is essential for the positive selection of CD4(+) T cells
-
Lo W.L., et al. A voltage-gated sodium channel is essential for the positive selection of CD4(+) T cells. Nat. Immunol. 2012, 13:880-887.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 880-887
-
-
Lo, W.L.1
-
48
-
-
84867283546
-
Tespa1 is a novel inositol 1,4,5-trisphosphate receptor binding protein in T and B lymphocytes
-
Matsuzaki H., et al. Tespa1 is a novel inositol 1,4,5-trisphosphate receptor binding protein in T and B lymphocytes. FEBS Open Bio 2012, 2:255-259.
-
(2012)
FEBS Open Bio
, vol.2
, pp. 255-259
-
-
Matsuzaki, H.1
-
49
-
-
84855957129
-
How the TCR balances sensitivity and specificity for the recognition of self and pathogens
-
Morris G.P., Allen P.M. How the TCR balances sensitivity and specificity for the recognition of self and pathogens. Nat. Immunol. 2012, 13:121-128.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 121-128
-
-
Morris, G.P.1
Allen, P.M.2
-
50
-
-
0029066263
-
A role for CD5 in TCR-mediated signal transduction and thymocyte selection
-
Tarakhovsky A., et al. A role for CD5 in TCR-mediated signal transduction and thymocyte selection. Science 1995, 269:535-537.
-
(1995)
Science
, vol.269
, pp. 535-537
-
-
Tarakhovsky, A.1
-
51
-
-
0032445491
-
CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity
-
Azzam H.S., et al. CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity. J. Exp. Med. 1998, 188:2301-2311.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2301-2311
-
-
Azzam, H.S.1
-
52
-
-
18644365981
-
Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4(+) T cells: evidence from a lymphopenic T cell model
-
Bhandoola A., et al. Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4(+) T cells: evidence from a lymphopenic T cell model. Immunity 2002, 17:425-436.
-
(2002)
Immunity
, vol.17
, pp. 425-436
-
-
Bhandoola, A.1
-
53
-
-
72949100401
-
Naive T cell homeostasis: from awareness of space to a sense of place
-
Takada K., Jameson S.C. Naive T cell homeostasis: from awareness of space to a sense of place. Nat. Rev. Immunol. 2009, 9:823-832.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 823-832
-
-
Takada, K.1
Jameson, S.C.2
-
54
-
-
78650583401
-
Role of antigen persistence and dose for CD4+ T-cell exhaustion and recovery
-
Han S., et al. Role of antigen persistence and dose for CD4+ T-cell exhaustion and recovery. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:20453-20458.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 20453-20458
-
-
Han, S.1
-
55
-
-
57449097558
-
Homeostasis of naive and memory T cells
-
Surh C.D., Sprent J. Homeostasis of naive and memory T cells. Immunity 2008, 29:848-862.
-
(2008)
Immunity
, vol.29
, pp. 848-862
-
-
Surh, C.D.1
Sprent, J.2
-
56
-
-
0037191792
-
Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes
-
Stefanova I., et al. Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes. Nature 2002, 420:429-434.
-
(2002)
Nature
, vol.420
, pp. 429-434
-
-
Stefanova, I.1
-
57
-
-
76949102246
-
T cell receptor-dependent regulation of lipid rafts controls naive CD8+ T cell homeostasis
-
Cho J.H., et al. T cell receptor-dependent regulation of lipid rafts controls naive CD8+ T cell homeostasis. Immunity 2010, 32:214-226.
-
(2010)
Immunity
, vol.32
, pp. 214-226
-
-
Cho, J.H.1
-
58
-
-
79959993826
-
Signaling thresholds govern heterogeneity in IL-7-receptor-mediated responses of naive CD8(+) T cells
-
Palmer M.J., et al. Signaling thresholds govern heterogeneity in IL-7-receptor-mediated responses of naive CD8(+) T cells. Immunol. Cell Biol. 2011, 89:581-594.
-
(2011)
Immunol. Cell Biol.
, vol.89
, pp. 581-594
-
-
Palmer, M.J.1
-
59
-
-
84912113033
-
Continuous T cell receptor signals maintain a functional regulatory T cell pool
-
Vahl J.C., et al. Continuous T cell receptor signals maintain a functional regulatory T cell pool. Immunity 2014, 41:722-736.
-
(2014)
Immunity
, vol.41
, pp. 722-736
-
-
Vahl, J.C.1
-
60
-
-
84908123494
-
Continuous requirement for the TCR in regulatory T cell function
-
Levine A.G., et al. Continuous requirement for the TCR in regulatory T cell function. Nat. Immunol. 2014, 15:1070-1078.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 1070-1078
-
-
Levine, A.G.1
-
61
-
-
0033180491
-
The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery
-
Ernst B., et al. The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity 1999, 11:173-181.
-
(1999)
Immunity
, vol.11
, pp. 173-181
-
-
Ernst, B.1
-
62
-
-
0033180494
-
Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts
-
Goldrath A.W., Bevan M.J. Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts. Immunity 1999, 11:183-190.
-
(1999)
Immunity
, vol.11
, pp. 183-190
-
-
Goldrath, A.W.1
Bevan, M.J.2
-
63
-
-
33645275372
-
Naive and memory CD4+ T cell survival controlled by clonal abundance
-
Hataye J., et al. Naive and memory CD4+ T cell survival controlled by clonal abundance. Science 2006, 312:114-116.
-
(2006)
Science
, vol.312
, pp. 114-116
-
-
Hataye, J.1
-
64
-
-
70350439671
-
An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells
-
Lo W.L., et al. An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells. Nat. Immunol. 2009, 10:1155-1161.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 1155-1161
-
-
Lo, W.L.1
-
65
-
-
84892621959
-
T cell immunodominance is dictated by the positively selecting self-peptide
-
Lo W.L., et al. T cell immunodominance is dictated by the positively selecting self-peptide. Elife 2014, 3:e01457.
-
(2014)
Elife
, vol.3
, pp. e01457
-
-
Lo, W.L.1
-
66
-
-
0035927093
-
Dynamic tuning of T cell reactivity by self-peptide-major histocompatibility complex ligands
-
Wong P., et al. Dynamic tuning of T cell reactivity by self-peptide-major histocompatibility complex ligands. J. Exp. Med. 2001, 193:1179-1187.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1179-1187
-
-
Wong, P.1
-
67
-
-
84874244135
-
T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens
-
Mandl J.N., et al. T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens. Immunity 2013, 38:263-274.
-
(2013)
Immunity
, vol.38
, pp. 263-274
-
-
Mandl, J.N.1
-
68
-
-
84894447120
-
Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC
-
Persaud S.P., et al. Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC. Nat. Immunol. 2014, 15:266-274.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 266-274
-
-
Persaud, S.P.1
-
69
-
-
84924979971
-
The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens
-
Fulton R.B., et al. The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens. Nat. Immunol. 2015, 16:107-117.
-
(2015)
Nat. Immunol.
, vol.16
, pp. 107-117
-
-
Fulton, R.B.1
-
70
-
-
84862190820
-
Distinct CD4+ helper T cells involved in primary and secondary responses to infection
-
Weber K.S., et al. Distinct CD4+ helper T cells involved in primary and secondary responses to infection. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:9511-9516.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 9511-9516
-
-
Weber, K.S.1
-
71
-
-
0033981410
-
Deriving quantitative constraints on T cell selection from data on the mature T cell repertoire
-
Detours V., et al. Deriving quantitative constraints on T cell selection from data on the mature T cell repertoire. J. Immunol. 2000, 164:121-128.
-
(2000)
J. Immunol.
, vol.164
, pp. 121-128
-
-
Detours, V.1
-
72
-
-
0028344533
-
Structure of peptides associated with class I and class II MHC molecules
-
Engelhard V.H. Structure of peptides associated with class I and class II MHC molecules. Annu. Rev. Immunol. 1994, 12:181-207.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 181-207
-
-
Engelhard, V.H.1
-
73
-
-
0032171644
-
A very high level of crossreactivity is an essential feature of the T-cell receptor
-
Mason D. A very high level of crossreactivity is an essential feature of the T-cell receptor. Immunol. Today 1998, 19:395-404.
-
(1998)
Immunol. Today
, vol.19
, pp. 395-404
-
-
Mason, D.1
-
74
-
-
1142274484
-
The many important facets of T-cell repertoire diversity
-
Nikolich-Zugich J., et al. The many important facets of T-cell repertoire diversity. Nat. Rev. Immunol. 2004, 4:123-132.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 123-132
-
-
Nikolich-Zugich, J.1
-
75
-
-
58149280299
-
T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity
-
Stone J.D., et al. T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity. Immunology 2009, 126:165-176.
-
(2009)
Immunology
, vol.126
, pp. 165-176
-
-
Stone, J.D.1
-
76
-
-
62249131518
-
Complete but curtailed T-cell response to very low-affinity antigen
-
Zehn D., et al. Complete but curtailed T-cell response to very low-affinity antigen. Nature 2009, 458:211-214.
-
(2009)
Nature
, vol.458
, pp. 211-214
-
-
Zehn, D.1
-
77
-
-
0028273017
-
Evidence for a differential avidity model of T cell selection in the thymus
-
Ashton-Rickardt P.G., et al. Evidence for a differential avidity model of T cell selection in the thymus. Cell 1994, 76:651-663.
-
(1994)
Cell
, vol.76
, pp. 651-663
-
-
Ashton-Rickardt, P.G.1
-
78
-
-
84871990243
-
Viral antigen density and confinement time regulate the reactivity pattern of CD4 T-cell responses to vaccinia virus infection
-
Vanguri V., et al. Viral antigen density and confinement time regulate the reactivity pattern of CD4 T-cell responses to vaccinia virus infection. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:288-293.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 288-293
-
-
Vanguri, V.1
-
79
-
-
84915752670
-
Force and affinity in ligand discrimination by the TCR
-
Depoil D., Dustin M.L. Force and affinity in ligand discrimination by the TCR. Trends Immunol. 2014, 35:597-603.
-
(2014)
Trends Immunol.
, vol.35
, pp. 597-603
-
-
Depoil, D.1
Dustin, M.L.2
-
80
-
-
84898644308
-
Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling
-
Liu B., et al. Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling. Cell 2014, 157:357-368.
-
(2014)
Cell
, vol.157
, pp. 357-368
-
-
Liu, B.1
-
81
-
-
84922370601
-
Force-dependent transition in the T-cell receptor beta-subunit allosterically regulates peptide discrimination and pMHC bond lifetime
-
Das D.K., et al. Force-dependent transition in the T-cell receptor beta-subunit allosterically regulates peptide discrimination and pMHC bond lifetime. Proc. Natl. Acad. Sci. U.S.A. 2015, 112:1517-1522.
-
(2015)
Proc. Natl. Acad. Sci. U.S.A.
, vol.112
, pp. 1517-1522
-
-
Das, D.K.1
-
82
-
-
84856004728
-
Mechanosensing in T lymphocyte activation
-
Judokusumo E., et al. Mechanosensing in T lymphocyte activation. Biophys. J. 2012, 102:L5-L7.
-
(2012)
Biophys. J.
, vol.102
, pp. L5-L7
-
-
Judokusumo, E.1
-
83
-
-
71449090489
-
The alphabeta T cell receptor is an anisotropic mechanosensor
-
Kim S.T., et al. The alphabeta T cell receptor is an anisotropic mechanosensor. J. Biol. Chem. 2009, 284:31028-31037.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 31028-31037
-
-
Kim, S.T.1
-
84
-
-
67349283033
-
Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor
-
Beddoe T., et al. Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor. Immunity 2009, 30:777-788.
-
(2009)
Immunity
, vol.30
, pp. 777-788
-
-
Beddoe, T.1
-
85
-
-
84856020544
-
Kinetics and mechanics of two-dimensional interactions between T cell receptors and different activating ligands
-
Robert P., et al. Kinetics and mechanics of two-dimensional interactions between T cell receptors and different activating ligands. Biophys. J. 2012, 102:248-257.
-
(2012)
Biophys. J.
, vol.102
, pp. 248-257
-
-
Robert, P.1
-
86
-
-
0033762433
-
Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition
-
Aivazian D., Stern L.J. Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition. Nat. Struct. Biol. 2000, 7:1023-1026.
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 1023-1026
-
-
Aivazian, D.1
Stern, L.J.2
-
87
-
-
55449138409
-
Regulation of T cell receptor activation by dynamic membrane binding of the CD3epsilon cytoplasmic tyrosine-based motif
-
Xu C., et al. Regulation of T cell receptor activation by dynamic membrane binding of the CD3epsilon cytoplasmic tyrosine-based motif. Cell 2008, 135:702-713.
-
(2008)
Cell
, vol.135
, pp. 702-713
-
-
Xu, C.1
-
88
-
-
82755165363
-
Basic residues in the T-cell receptor zeta cytoplasmic domain mediate membrane association and modulate signaling
-
Zhang H., et al. Basic residues in the T-cell receptor zeta cytoplasmic domain mediate membrane association and modulate signaling. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:19323-19328.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 19323-19328
-
-
Zhang, H.1
-
89
-
-
84871909015
-
Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3epsilon cytoplasmic domain
-
Gagnon E., et al. Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3epsilon cytoplasmic domain. J. Exp. Med. 2012, 209:2423-2439.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 2423-2439
-
-
Gagnon, E.1
-
90
-
-
84871736291
-
Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids
-
Shi X., et al. Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids. Nature 2013, 493:111-115.
-
(2013)
Nature
, vol.493
, pp. 111-115
-
-
Shi, X.1
-
91
-
-
0024992268
-
Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo
-
Pircher H., et al. Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo. Nature 1990, 346:629-633.
-
(1990)
Nature
, vol.346
, pp. 629-633
-
-
Pircher, H.1
-
92
-
-
0034928717
-
CD4+ T-cell-epitope escape mutant virus selected in vivo
-
Ciurea A., et al. CD4+ T-cell-epitope escape mutant virus selected in vivo. Nat. Med. 2001, 7:795-800.
-
(2001)
Nat. Med.
, vol.7
, pp. 795-800
-
-
Ciurea, A.1
-
93
-
-
0037122796
-
Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes
-
Barouch D.H., et al. Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes. Nature 2002, 415:335-339.
-
(2002)
Nature
, vol.415
, pp. 335-339
-
-
Barouch, D.H.1
-
94
-
-
84918501014
-
Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis
-
Gaiha G.D., et al. Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis. Immunity 2014, 41:1001-1012.
-
(2014)
Immunity
, vol.41
, pp. 1001-1012
-
-
Gaiha, G.D.1
-
95
-
-
84893711428
-
Tolerance and exhaustion: defining mechanisms of T cell dysfunction
-
Schietinger A., Greenberg P.D. Tolerance and exhaustion: defining mechanisms of T cell dysfunction. Trends Immunol. 2014, 35:51-60.
-
(2014)
Trends Immunol.
, vol.35
, pp. 51-60
-
-
Schietinger, A.1
Greenberg, P.D.2
-
96
-
-
0037290768
-
Epitope dominance, competition and T cell affinity maturation
-
Kedl R.M., et al. Epitope dominance, competition and T cell affinity maturation. Curr. Opin. Immunol. 2003, 15:120-127.
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 120-127
-
-
Kedl, R.M.1
-
97
-
-
77955375356
-
Attenuated T cell responses to a high-potency ligand in vivo
-
Corse E., et al. Attenuated T cell responses to a high-potency ligand in vivo. PLoS Biol. 2010, 8:e1000481.
-
(2010)
PLoS Biol.
, vol.8
, pp. e1000481
-
-
Corse, E.1
-
98
-
-
33747041065
-
CD8 T cell competition for dendritic cells in vivo is an early event in activation
-
Willis R.A., et al. CD8 T cell competition for dendritic cells in vivo is an early event in activation. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:12063-12068.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 12063-12068
-
-
Willis, R.A.1
-
99
-
-
84911201387
-
Molecular regulation of effector and memory T cell differentiation
-
Chang J.T., et al. Molecular regulation of effector and memory T cell differentiation. Nat. Immunol. 2014, 15:1104-1115.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 1104-1115
-
-
Chang, J.T.1
|