A THEMIS:SHP1 complex promotes T-cell survival

EMBO Journal

Volumn 34, Issue 3, 2015, Pages 393-409

  Paster, Wolfgang ^a,i   Bruger, Annika M ^a   Katsch, Kristin ^a   Grégoire, Claude ^b,c   Roncagalli, Romain ^b,c   Fu, Guo ^d,h   Gascoigne, Nicholas R J ^d,e   Nika, Konstantina ^a   Cohnen, Andre ^a   Feller, Stephan M ^f,g   Simister, Philip C ^f   Molder, Kelly C ^a   Cordoba, Shaun Paul ^a   Dushek, Omer ^a   Malissen, Bernard ^b,c   Acuto, Oreste ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^c INSERM   (France)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^h XIAMEN UNIVERSITY   (China)

ⁱ MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

apoptosis; negative feedback; SHP1; TCR; THEMIS

Indexed keywords

CD3 ANTIGEN; CD69 ANTIGEN; CELL PROTEIN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN SH3; PROTEIN THEMIS; PROTEIN TYROSINE PHOSPHATASE SHP 1; SERINE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; CD3E PROTEIN, MOUSE; GRB2 PROTEIN, HUMAN; GRB2 PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; MULTIPROTEIN COMPLEX; PROTEIN; PROTEIN KINASE LCK; PROTEIN TYROSINE PHOSPHATASE SHP 2; PTPN11 PROTEIN, MOUSE; SIGNAL PEPTIDE; THEMIS PROTEIN, MOUSE; THYMOCYTE-EXPRESSED MOLECULE INVOLVED IN SELECTION, HUMAN;

ANIMAL CELL; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL MATURATION; CELL SURVIVAL; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LYMPHOCYTE DIFFERENTIATION; NEGATIVE FEEDBACK; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; GENETICS; JURKAT CELL LINE; KNOCKOUT MOUSE; METABOLISM; MOUSE; MUTATION; SRC HOMOLOGY DOMAIN;

ANIMALS; ANTIGENS, CD3; CELL DIFFERENTIATION; CELL SURVIVAL; GRB2 ADAPTOR PROTEIN; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MICE; MICE, KNOCKOUT; MULTIPROTEIN COMPLEXES; MUTATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; PROTEINS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; T-LYMPHOCYTES;

EID: 84922257832     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201387725     Document Type: Article

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