메뉴 건너뛰기




Volumn 164, Issue 1, 2000, Pages 121-128

Deriving quantitative constraints on T cell selection from data on the mature T cell repertoire

Author keywords

[No Author keywords available]

Indexed keywords

ALLOIMMUNITY; ANTIGEN RECOGNITION; ARTICLE; CALCULATION; CELL SELECTION; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MATHEMATICAL MODEL; PRIORITY JOURNAL; T LYMPHOCYTE; THYMUS;

EID: 0033981410     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.1.121     Document Type: Article
Times cited : (30)

References (78)
  • 3
    • 0017688347 scopus 로고
    • In a radiation chimaera, host H-2 antigens determine immune responsiveness of donor cytotoxic cells
    • Bevan, M. J. 1977. In a radiation chimaera, host H-2 antigens determine immune responsiveness of donor cytotoxic cells. Nature 269:417.
    • (1977) Nature , vol.269 , pp. 417
    • Bevan, M.J.1
  • 4
    • 0018197433 scopus 로고
    • The influence of the major histocompatibility complex on the function of T-helper cells in antibody formation
    • Waldmann, H. 1978. The influence of the major histocompatibility complex on the function of T-helper cells in antibody formation. Immunol. Rev. 42:202.
    • (1978) Immunol. Rev. , vol.42 , pp. 202
    • Waldmann, H.1
  • 5
    • 0018197434 scopus 로고
    • Thymus and lymphohemopoietic cells: Their role in T cell maturation in selection of T cells' H-2-restriction-specificity and in H-2 linked Ir gene control
    • Zinkernagel, R. M. 1978. Thymus and lymphohemopoietic cells: their role in T cell maturation in selection of T cells' H-2-restriction-specificity and in H-2 linked Ir gene control. Immunol. Rev. 42:224.
    • (1978) Immunol. Rev. , vol.42 , pp. 224
    • Zinkernagel, R.M.1
  • 6
    • 0009347131 scopus 로고
    • The role of gene products of the major histocompatibility complex in T cell activation and cellular interactions
    • W. E. Paul. ed. Raven Press, New York.
    • Schwartz, R. H. 1984. The role of gene products of the major histocompatibility complex in T cell activation and cellular interactions. In Fundamental Immunology, 1st Ed., W. E. Paul. ed. Raven Press, New York. p. 379.
    • (1984) Fundamental Immunology, 1st Ed. , pp. 379
    • Schwartz, R.H.1
  • 7
    • 0025231503 scopus 로고
    • Developmental biology of T cells in T cell-receptor transgenic mice
    • von Boehmer, H. 1990. Developmental biology of T cells in T cell-receptor transgenic mice. Annu. Rev. Immunol. 8:531.
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 531
    • Von Boehmer, H.1
  • 8
    • 0028151819 scopus 로고
    • Negative selection of lymphocytes
    • Nossal, G. J. 1994. Negative selection of lymphocytes. Cell 76:229.
    • (1994) Cell , vol.76 , pp. 229
    • Nossal, G.J.1
  • 9
    • 0029007485 scopus 로고
    • Intrathymic and extrathymic clonal deletion of T cells
    • Sprent, J., and S. R. Webb. 1995. Intrathymic and extrathymic clonal deletion of T cells. Curr. Opin. Immunol. 7:196.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 196
    • Sprent, J.1    Webb, S.R.2
  • 10
    • 0026030196 scopus 로고
    • +) thymocytes as post-selection intermediates leading to mature T cells
    • +) thymocytes as post-selection intermediates leading to mature T cells. J. Exp. Med. 173:32.
    • (1991) J. Exp. Med. , vol.173 , pp. 32
    • Shortman, K.1    Vremec, D.2    Egerton, M.3
  • 11
    • 0017227784 scopus 로고
    • H-2 antigen-specific cytotoxic T cells induced by concanavalin A: Estimation of their relative frequency
    • Bevan, M. J., R. E. Langman, and M. Cohn. 1976. H-2 antigen-specific cytotoxic T cells induced by concanavalin A: estimation of their relative frequency. Eur. J. Immunol. 6:150.
    • (1976) Eur. J. Immunol. , vol.6 , pp. 150
    • Bevan, M.J.1    Langman, R.E.2    Cohn, M.3
  • 12
    • 0022645825 scopus 로고
    • High frequency and nonrandom distribution of alloreactivity in T cell clones selected for recognition of foreign antigen in association with self class 11 molecules
    • Ashwell, J. D., C. Chen, and R. H. Schwartz 1986. High frequency and nonrandom distribution of alloreactivity in T cell clones selected for recognition of foreign antigen in association with self class 11 molecules. J. Immunol. 136:389.
    • (1986) J. Immunol. , vol.136 , pp. 389
    • Ashwell, J.D.1    Chen, C.2    Schwartz, R.H.3
  • 13
    • 0011933946 scopus 로고
    • H-2 restriction as a consequence of intentional priming: T cells of fully allogeneic chimeric mice as well as of normal mice respond to foreign antigens in the context of H-2 determinants not encountered on thymic epithelial cells
    • Stockinger, H., K. Pfizenmaier, C. Hardt, H. Rodt, M. Rollinghoff, and H. Wagner. 1980. H-2 restriction as a consequence of intentional priming: T cells of fully allogeneic chimeric mice as well as of normal mice respond to foreign antigens in the context of H-2 determinants not encountered on thymic epithelial cells. Proc. Natl. Acad. Sci. USA 77:7390.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 7390
    • Stockinger, H.1    Pfizenmaier, K.2    Hardt, C.3    Rodt, H.4    Rollinghoff, M.5    Wagner, H.6
  • 14
    • 0030024279 scopus 로고    scopus 로고
    • Immunology taught by viruses
    • Zinkernagel, R. M. 1996. Immunology taught by viruses. Science 271:173.
    • (1996) Science , vol.271 , pp. 173
    • Zinkernagel, R.M.1
  • 15
    • 0033592574 scopus 로고    scopus 로고
    • A quantitative theory of affinity-driven T cell repertoire seleclion
    • Detours, V., R. Mehr, and A. S. Perelson. 1999. A quantitative theory of affinity-driven T cell repertoire seleclion. J. Theor. Biol. 200:389.
    • (1999) J. Theor. Biol. , vol.200 , pp. 389
    • Detours, V.1    Mehr, R.2    Perelson, A.S.3
  • 16
    • 0033609160 scopus 로고    scopus 로고
    • Explaining high alloreactivity as a quantitative consequence of affinity-driven selection of thymocytes
    • Detours, V., and A. S. Perelson. 1999. Explaining high alloreactivity as a quantitative consequence of affinity-driven selection of thymocytes. Proc. Natl. Acad. Sci. USA 96:-5153.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5153
    • Detours, V.1    Perelson, A.S.2
  • 17
    • 0018567632 scopus 로고
    • Theoretical studies of clonal selection: Minimal antibody repertoire size and reliability of self-nonself discrimination
    • Perelson, A. S. and G. F. Oster. 1979. Theoretical studies of clonal selection: minimal antibody repertoire size and reliability of self-nonself discrimination. J. Theor. Biol. 81:645.
    • (1979) J. Theor. Biol. , vol.81 , pp. 645
    • Perelson, A.S.1    Oster, G.F.2
  • 19
  • 20
    • 0025261988 scopus 로고
    • Somatic mutation, affinity maturation and the antibody repertoire: A computer model
    • Weinand, R. G. 1990. Somatic mutation, affinity maturation and the antibody repertoire: a computer model. J. Theor. Biol. 143:343.
    • (1990) J. Theor. Biol. , vol.143 , pp. 343
    • Weinand, R.G.1
  • 21
    • 0027414469 scopus 로고
    • Probability model for molecular recognition in biological receptor repertoires: Significance to the olfactory system
    • Lancet, D., E. Sadovsky, and E. Seidemann. 1993. Probability model for molecular recognition in biological receptor repertoires: significance to the olfactory system. Proc. Natl. Acad. Sci. USA 90:3715.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3715
    • Lancet, D.1    Sadovsky, E.2    Seidemann, E.3
  • 22
    • 0028943275 scopus 로고
    • The three-dimensional structure of peptide-MHC complexes
    • Madden, D. R. 1995. The three-dimensional structure of peptide-MHC complexes. Annu. Rev. Immunol. 13:587.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 587
    • Madden, D.R.1
  • 24
    • 0030935007 scopus 로고    scopus 로고
    • The MHC reactivity of the T cell repertoire prior to positive and negative selection
    • Zerrahn, J., W. Held, and D. H. Raulet. 1997. The MHC reactivity of the T cell repertoire prior to positive and negative selection. Cell 88:627.
    • (1997) Cell , vol.88 , pp. 627
    • Zerrahn, J.1    Held, W.2    Raulet, D.H.3
  • 26
    • 0016318314 scopus 로고
    • Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis
    • Zinkernagel, R. M., and P. C. Doherty. 1974. Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis. Nature 251:547
    • (1974) Nature , vol.251 , pp. 547
    • Zinkernagel, R.M.1    Doherty, P.C.2
  • 27
    • 0026447431 scopus 로고
    • The optimal number of major histocompatibility complex molecules in an individual
    • Nowak, M. A., K. Tarczy-Hornoch, and J. M. Austyn. 1992. The optimal number of major histocompatibility complex molecules in an individual. Proc. Natl. Acad. Sci. USA 89:10896.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10896
    • Nowak, M.A.1    Tarczy-Hornoch, K.2    Austyn, J.M.3
  • 29
    • 0027448514 scopus 로고
    • On the plausibility of the clonal expansion theory of the immune system in terms of the combinatorial possibilities of amino-acids in antigen and self-tolerance
    • Whitaker, L. and A. M. Renton. 1993. On the plausibility of the clonal expansion theory of the immune system in terms of the combinatorial possibilities of amino-acids in antigen and self-tolerance. J. Theor. Biol. 164:531.
    • (1993) J. Theor. Biol. , vol.164 , pp. 531
    • Whitaker, L.1    Renton, A.M.2
  • 30
    • 0030064106 scopus 로고    scopus 로고
    • Antigen receptor "capacity" and the sensitivity of self-tolerance
    • Nemazee, D. 1996. Antigen receptor "capacity" and the sensitivity of self-tolerance. Immunol. Today 17:25
    • (1996) Immunol. Today , vol.17 , pp. 25
    • Nemazee, D.1
  • 31
    • 0030299912 scopus 로고    scopus 로고
    • The role of peptide specificity in MHC class I-restricted allogeneic responses
    • Frelinger, J. A., and M. McMillan. 1996. The role of peptide specificity in MHC class I-restricted allogeneic responses. Immunol. Rev. 154:45.
    • (1996) Immunol. Rev. , vol.154 , pp. 45
    • Frelinger, J.A.1    McMillan, M.2
  • 34
    • 0026733449 scopus 로고
    • Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size
    • Chicz, R. M., R. G. Urban, W. S. Lane, J. C. Gorga, L. J. Stern, D. A. Vignali, and J. L. Strominger. 1992. Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size. Nature 358:764.
    • (1992) Nature , vol.358 , pp. 764
    • Chicz, R.M.1    Urban, R.G.2    Lane, W.S.3    Gorga, J.C.4    Stern, L.J.5    Vignali, D.A.6    Strominger, J.L.7
  • 37
    • 0028344533 scopus 로고
    • Structure of peptides associated with class I and class II MHC molecules
    • Engelhard, V. H. 1994. Structure of peptides associated with class I and class II MHC molecules. Annu. Rev. Immunol. 12:181.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 181
    • Engelhard, V.H.1
  • 38
    • 0030806085 scopus 로고    scopus 로고
    • In thymic selection, peptide diversity gives and takes away
    • Bevan, M. J. 1997. In thymic selection, peptide diversity gives and takes away. Immunity 7:175.
    • (1997) Immunity , vol.7 , pp. 175
    • Bevan, M.J.1
  • 39
    • 0029855347 scopus 로고    scopus 로고
    • Structure of the complex between human T-cell receptor, viral peptide and HLA-A2
    • Garbocvi, D. N., P. Ghosh, U. Utz, Q. R. Fan, W. E. Biddison, and D. C. Wiley. 1996. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature 384:114.
    • (1996) Nature , vol.384 , pp. 114
    • Garbocvi, D.N.1    Ghosh, P.2    Utz, U.3    Fan, Q.R.4    Biddison, W.E.5    Wiley, D.C.6
  • 40
    • 18344405559 scopus 로고    scopus 로고
    • Two human T cell receptors hind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids
    • Ding, Y., K. J. Smith, D. N. Garboczi, U. Utz, W. E. Biddison, and D. C. Wiley. 1998. Two human T cell receptors hind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids. Immunity 8:403.
    • (1998) Immunity , vol.8 , pp. 403
    • Ding, Y.1    Smith, K.J.2    Garboczi, D.N.3    Utz, U.4    Biddison, W.E.5    Wiley, D.C.6
  • 41
    • 0032549142 scopus 로고    scopus 로고
    • Structural basis of plasticity in T cell receptor recognition of self peptide-MHC antigen
    • Garcia, K. C., M. Degano, L. R. Pease, M. Huang, P. A. Peterson, L. Teyton, and I. A. Wilson. 1998. Structural basis of plasticity in T cell receptor recognition of self peptide-MHC antigen. Nature 279:1166.
    • (1998) Nature , vol.279 , pp. 1166
    • Garcia, K.C.1    Degano, M.2    Pease, L.R.3    Huang, M.4    Peterson, P.A.5    Teyton, L.6    Wilson, I.A.7
  • 43
    • 0026621224 scopus 로고
    • Atomic structure of a human MHC molecule presenting an influenza virus peptide
    • Silver, M. L., H. Guo, J. L. Strominger, and D. C. Wiley. 1992. Atomic structure of a human MHC molecule presenting an influenza virus peptide. Nature 360:367.
    • (1992) Nature , vol.360 , pp. 367
    • Silver, M.L.1    Guo, H.2    Strominger, J.L.3    Wiley, D.C.4
  • 45
    • 0030058657 scopus 로고    scopus 로고
    • The repertoire of T cells shaped by a single MHC/peptide ligand
    • Ignatowicz, L., J. Kappler, and P. Marrack. 1996. The repertoire of T cells shaped by a single MHC/peptide ligand. Cell 84:521.
    • (1996) Cell , vol.84 , pp. 521
    • Ignatowicz, L.1    Kappler, J.2    Marrack, P.3
  • 49
    • 0029835390 scopus 로고    scopus 로고
    • Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex
    • Laufer, T. M., J. DeKonig, J. S. Markowitz, D. Lo, and L. H. Glimcher, 1996. Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex. Nature 383:81.
    • (1996) Nature , vol.383 , pp. 81
    • Laufer, T.M.1    DeKonig, J.2    Markowitz, J.S.3    Lo, D.4    Glimcher, L.H.5
  • 51
    • 0029082346 scopus 로고
    • Thymic selection and cell division
    • Ernst, B., C. D. Surh, and J. Sprent. 1995. Thymic selection and cell division. J. Exp. Med. 182:961.
    • (1995) J. Exp. Med. , vol.182 , pp. 961
    • Ernst, B.1    Surh, C.D.2    Sprent, J.3
  • 52
    • 0028988659 scopus 로고
    • Thymic emigration: Conveyor belts or lucky dips?
    • Scollay, R., and D. I. Godfrey. 1995. Thymic emigration: conveyor belts or lucky dips? Immunol. Today 16:268.
    • (1995) Immunol. Today , vol.16 , pp. 268
    • Scollay, R.1    Godfrey, D.I.2
  • 53
    • 0031573129 scopus 로고    scopus 로고
    • Expansion of mature thymocyte subsets before emigration to the periphery
    • Penit, C., and F. Vasseur. 1997. Expansion of mature thymocyte subsets before emigration to the periphery. J. Immunol. 159:4848.
    • (1997) J. Immunol. , vol.159 , pp. 4848
    • Penit, C.1    Vasseur, F.2
  • 55
    • 0028229558 scopus 로고
    • Production, selection, and maturation of thymocytes with high surface density of TCR
    • Lucas, B., F. Vasseur, and C. Penit. 1994. Production, selection, and maturation of thymocytes with high surface density of TCR. J. Immunol. 153:53.
    • (1994) J. Immunol. , vol.153 , pp. 53
    • Lucas, B.1    Vasseur, F.2    Penit, C.3
  • 56
    • 0032522808 scopus 로고    scopus 로고
    • Identification of a developmentally regulated phase of postselection expasion driven by thymic epithelium
    • Hare, K. J., R. W. Wilkinson, E. J. Jenkinson, and G. Anderson. 1998. Identification of a developmentally regulated phase of postselection expasion driven by thymic epithelium. J. Immunol. 160:3666.
    • (1998) J. Immunol. , vol.160 , pp. 3666
    • Hare, K.J.1    Wilkinson, R.W.2    Jenkinson, E.J.3    Anderson, G.4
  • 57
    • 0016345568 scopus 로고
    • Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogencic system
    • Zinkernagel, R. M., and P. C. Doherty. 1974. Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogencic system. Nature 248:701.
    • (1974) Nature , vol.248 , pp. 701
    • Zinkernagel, R.M.1    Doherty, P.C.2
  • 58
    • 0018197431 scopus 로고
    • The influence of thymus H-2 antigens on the specilicity of maturing killer and helper cells
    • Bevan, M. J., and P. J. Fink. 1978. The influence of thymus H-2 antigens on the specilicity of maturing killer and helper cells. Immunol. Rev. 42:3.
    • (1978) Immunol. Rev. , vol.42 , pp. 3
    • Bevan, M.J.1    Fink, P.J.2
  • 59
    • 0018197429 scopus 로고
    • Role of H-2 gene products in the function of T helper cells from normal and chimeric mice in vivo
    • Sprent, J. 1978. Role of H-2 gene products in the function of T helper cells from normal and chimeric mice in vivo, Immunol. Rev. 42:108.
    • (1978) Immunol. Rev. , vol.42 , pp. 108
    • Sprent, J.1
  • 61
    • 0019315941 scopus 로고
    • MHC restriction, self-tolerance and the thymus
    • Howard, J. 1980. MHC restriction, self-tolerance and the thymus. Nature 286:15.
    • (1980) Nature , vol.286 , pp. 15
    • Howard, J.1
  • 62
    • 0019313523 scopus 로고
    • An examination of MHC restriction in the context of a minimal clonal abortion model for self tolerance
    • Doherty, P. C., and J. R. Bennink. 1980. An examination of MHC restriction in the context of a minimal clonal abortion model for self tolerance. Scand, J. Immunol. 12:271.
    • (1980) Scand, J. Immunol. , vol.12 , pp. 271
    • Doherty, P.C.1    Bennink, J.R.2
  • 63
    • 0027329978 scopus 로고
    • Why positive selection?
    • Matzinger, P. 1993. Why positive selection? Immunol. Rev. 135:81.
    • (1993) Immunol. Rev. , vol.135 , pp. 81
    • Matzinger, P.1
  • 64
    • 0028920919 scopus 로고
    • The positively selected T cell repertoire: Is it exclusively restricted to the selecting MHC?
    • Nanda, N. K., and E. E. Sercarz. 1995. The positively selected T cell repertoire: is it exclusively restricted to the selecting MHC? Intl. Immunol. 7:353.
    • (1995) Intl. Immunol. , vol.7 , pp. 353
    • Nanda, N.K.1    Sercarz, E.E.2
  • 65
    • 0028913816 scopus 로고
    • Ligands for the T-cell receptor: Hard times for avidity models
    • Janeway, C. A. 1995. Ligands for the T-cell receptor: hard times for avidity models. Immunol. Today 16:223.
    • (1995) Immunol. Today , vol.16 , pp. 223
    • Janeway, C.A.1
  • 66
    • 0027974989 scopus 로고
    • The three-dimentional structure of H-2Dh at 2.4 Å resolution: Implications for antigen-determinant selection
    • Young, A. C. M., W. Zhang, J. C. Sacchettini, and S. G. Nathenson. 1994. The three-dimentional structure of H-2Dh at 2.4 Å resolution: implications for antigen-determinant selection. Cell 76:39.
    • (1994) Cell , vol.76 , pp. 39
    • Young, A.C.M.1    Zhang, W.2    Sacchettini, J.C.3    Nathenson, S.G.4
  • 67
    • 0026728457 scopus 로고
    • Emerging principles for the recognition of peptide antigens by MHC class I molecules
    • Matsumura, M., D. H. Fremont, P. A. Peterson, and I. A. Wilson. 1992. Emerging principles for the recognition of peptide antigens by MHC class I molecules. Science 257:927.
    • (1992) Science , vol.257 , pp. 927
    • Matsumura, M.1    Fremont, D.H.2    Peterson, P.A.3    Wilson, I.A.4
  • 68
    • 0029091980 scopus 로고
    • Nonclassical binding of formylated peptide in crystal structure of the MHC class Ib molecule H-2M3
    • Wang, C. R., A. R. Castaño, P. A. Peterson, C. Slaughter, K. F. Lindahl, and J. Deisenhofer. 1995. Nonclassical binding of formylated peptide in crystal structure of the MHC class Ib molecule H-2M3. Cell 82:655.
    • (1995) Cell , vol.82 , pp. 655
    • Wang, C.R.1    Castaño, A.R.2    Peterson, P.A.3    Slaughter, C.4    Lindahl, K.F.5    Deisenhofer, J.6
  • 69
    • 0028987213 scopus 로고
    • b-ovalbumine peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove
    • b-ovalbumine peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove. Proc. Natl. Acad. Sci. USA 92:2479.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2479
    • Fremont, D.H.1    Stura, M.2    Matsumura, E.A.3    Peterson, P.A.4    Wilson, I.A.5
  • 71
    • 0025791952 scopus 로고
    • T cell receptor genes in a series of class I major histocompatibility complex-restricted cytoloxic T lymphocyte clones specific for a plasmodium berghey nonapeptide; implications for T cell allelic exclusion and antigen-specific repertoire
    • Casanova, J. L., P. Romero, C. Widman, P. Kouritsky, and J. L. Maryanski. 1991. T cell receptor genes in a series of class I major histocompatibility complex-restricted cytoloxic T lymphocyte clones specific for a Plasmodium berghey nonapeptide; implications for T cell allelic exclusion and antigen-specific repertoire. J. Exp. Med. 174:1371.
    • (1991) J. Exp. Med. , vol.174 , pp. 1371
    • Casanova, J.L.1    Romero, P.2    Widman, C.3    Kouritsky, P.4    Maryanski, J.L.5
  • 72
    • 0026721377 scopus 로고
    • Exclusion and inclusion of α and β T cell receptor alleles
    • Borgulya, P., H. Kishi, Y. Uematsu, and H. von Boehmer. 1992, Exclusion and inclusion of α and β T cell receptor alleles. Cell 69:529.
    • (1992) Cell , vol.69 , pp. 529
    • Borgulya, P.1    Kishi, H.2    Uematsu, Y.3    Von Boehmer, H.4
  • 75
    • 0027220211 scopus 로고
    • Multiple rearrangements in T cell receptor a chain genes maximize the production of useful thymocytes
    • Petrie, H. T., F. Livak, D. G. Schatz, A. Strasser, I. N. Crispe, and K. Shortman. 1993. Multiple rearrangements in T cell receptor a chain genes maximize the production of useful thymocytes. J. Exp. Med. 178:615.
    • (1993) J. Exp. Med. , vol.178 , pp. 615
    • Petrie, H.T.1    Livak, F.2    Schatz, D.G.3    Strasser, A.4    Crispe, I.N.5    Shortman, K.6
  • 76
    • 0028900682 scopus 로고
    • The influence of positive selection on RAG expression in thymocytes
    • Kouskoff, V., J. L. Vonesch, C. Benoist, and D. Mathis. 1995. The influence of positive selection on RAG expression in thymocytes. Eur. J. Immunol. 25:54.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 54
    • Kouskoff, V.1    Vonesch, J.L.2    Benoist, C.3    Mathis, D.4
  • 78
    • 0029810903 scopus 로고    scopus 로고
    • Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function
    • Zal, T., S. Weiss, A. Mellor, and B. Stockinger. 1996. Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function. Proc. Natl. Acad. Sci. USA 93:9102.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9102
    • Zal, T.1    Weiss, S.2    Mellor, A.3    Stockinger, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.