Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lynphocytes

Nature

Volumn 415, Issue 6869, 2002, Pages 335-339

  Barouch, Dan H ^a   Kunstman, Jennifer ^b   Kuroda, Marcelo J ^a   Schmitz, Jörn E ^a   Santra, Sampa ^a   Peyerl, Fred W ^a   Krivulka, Georgia R ^a   Beaudry, Kristin ^a   Lifton, Michelle A ^a   Gorgone, Darci A ^a   Montefiori, David C ^c   Lewis, Mark G ^d   Wolinsky, Steven M ^b   Letvin, Norman L ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTAGENESIS; PATHOLOGY; RNA; VACCINES;

PARTIAL IMMUNE PROTECTION;

VIRUSES;

HUMAN IMMUNODEFICIENCY VIRUS VACCINE; VIRUS RNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; MUTATION; VACCINATION;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AIDS RELATED COMPLEX; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DISEASE COURSE; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; TREATMENT FAILURE; VACCINATION; VIRUS HYBRID; VIRUS REPLICATION;

ACQUIRED IMMUNODEFICIENCY SYNDROME; AIDS VACCINES; AMINO ACID SUBSTITUTION; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; DNA MUTATIONAL ANALYSIS; EPITOPES, T-LYMPHOCYTE; GENES, GAG; HIV-1; HUMANS; IMMUNITY; LYMPHOCYTE DEPLETION; MACACA MULATTA; MUTATION; SAIDS VACCINES; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; T-LYMPHOCYTES, CYTOTOXIC; VACCINES, SYNTHETIC; VIRUS REPLICATION;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; MACACA MULATTA; RNA VIRUSES; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS; SIMIAN-HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0037122796     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/415335a     Document Type: Article

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