Optimal T-cell receptor affinity for inducing autoimmunity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 48, 2014, Pages 17248-17253

  Koehli, Sabrina ^a   Naeher, Dieter ^a   Galati Fournier, Virginie ^a   Zehn, Dietmar ^b,c   Palmer, Ed ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b Swiss Vaccine Research Institute   (Switzerland)

^c LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Affinity; Autoimmunity; T cell; TCR; Tolerance

Indexed keywords

T LYMPHOCYTE RECEPTOR; AUTOANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; OVALBUMIN; PROTEIN BINDING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CONTROLLED STUDY; CYTOLYSIS; FLOW CYTOMETRY; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PHENOTYPE; RECEPTOR AFFINITY; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE; ANIMAL; BINDING COMPETITION; C57BL MOUSE; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; TRANSGENIC MOUSE;

MUS; MUS MUSCULUS;

ANIMALS; AUTOANTIGENS; AUTOIMMUNITY; BINDING, COMPETITIVE; DIABETES MELLITUS, TYPE 1; FLOW CYTOMETRY; INSULIN-SECRETING CELLS; MICE, INBRED C57BL; MICE, TRANSGENIC; OVALBUMIN; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL; SELF TOLERANCE; T-LYMPHOCYTES;

EID: 84915747866     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1402724111     Document Type: Article

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