Signaling thresholds govern heterogeneity in IL-7-receptor-mediated responses of nave CD8 T cells

Immunology and Cell Biology

Volumn 89, Issue 5, 2011, Pages 581-594

  Palmer, Megan J ^a   Mahajan, Vinay S ^a   Chen, Jianzhu ^b   Irvine, Darrell J ^a,b,c   Lauffenburger, Douglas A ^a,b  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

homeostasis; IL 7; na ve T cells; signaling

Indexed keywords

CD5 ANTIGEN; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CELL SURVIVAL; HOMEOSTASIS; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD5; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYTOKINES; GENE EXPRESSION REGULATION; HOMEOSTASIS; IMMUNOLOGIC FACTORS; INTERLEUKIN-7; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; RECEPTORS, INTERLEUKIN-7; SIGNAL TRANSDUCTION;

MUS;

EID: 79959993826     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2011.5     Document Type: Article

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