-
1
-
-
14544288635
-
The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment
-
He, X. et al. The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. Nature 433 826-833 (2005).
-
(2005)
Nature
, vol.433
, pp. 826-833
-
-
He, X.1
-
2
-
-
33644839920
-
Role of Bim and other Bcl-2 family members in autoimmune and degenerative diseases
-
Hughes, P., Bouillet, P. & Strasser, A. Role of Bim and other Bcl-2 family members in autoimmune and degenerative diseases. Curr. Dir. Autoimmun. 9, 74-94 (2006).
-
(2006)
Curr. Dir. Autoimmun
, vol.9
, pp. 74-94
-
-
Hughes, P.1
Bouillet, P.2
Strasser, A.3
-
3
-
-
0018862265
-
Purinogenic immunodeficiency diseases: Clinical features and molecular mechanisms
-
Mitchell, B.S. & Kelley, W.N. Purinogenic immunodeficiency diseases: clinical features and molecular mechanisms. Ann. Intern. Med. 92, 826-831 (1980).
-
(1980)
Ann. Intern. Med
, vol.92
, pp. 826-831
-
-
Mitchell, B.S.1
Kelley, W.N.2
-
4
-
-
37049019860
-
Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions
-
Siggs, O.M. et al. Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions. Immunity 27, 912-926 (2007).
-
(2007)
Immunity
, vol.27
, pp. 912-926
-
-
Siggs, O.M.1
-
5
-
-
2942579099
-
Epigenetic gene silencing by Runx proteins
-
Taniuchi, I. & Littman, D.R. Epigenetic gene silencing by Runx proteins. Oncogene 23, 4341-4345 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 4341-4345
-
-
Taniuchi, I.1
Littman, D.R.2
-
6
-
-
33745197598
-
Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia
-
Weerkamp, F., van Dongen, J.J. & Staal, F.J. Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia. Leukemia 20, 1197-1205 (2006).
-
(2006)
Leukemia
, vol.20
, pp. 1197-1205
-
-
Weerkamp, F.1
van Dongen, J.J.2
Staal, F.J.3
-
7
-
-
0036582215
-
T-cell development and the CD4-CD8 lineage decision
-
Germain, R.N. T-cell development and the CD4-CD8 lineage decision. Nat. Rev. Immunol. 2, 309-322 (2002).
-
(2002)
Nat. Rev. Immunol
, vol.2
, pp. 309-322
-
-
Germain, R.N.1
-
8
-
-
0033696201
-
Lck activity controls CD4/CD8 T cell lineage commitment
-
Hernandez-Hoyos, G., Sohn, S.J., Rothenberg, E.V. & Alberola-Ila, J. Lck activity controls CD4/CD8 T cell lineage commitment. Immunity 12, 313-322 (2000).
-
(2000)
Immunity
, vol.12
, pp. 313-322
-
-
Hernandez-Hoyos, G.1
Sohn, S.J.2
Rothenberg, E.V.3
Alberola-Ila, J.4
-
9
-
-
23944494669
-
-
Kappes, D.J. & He, X. CD4-CD8 lineage commitment: An inside view. Nat. Immunol. 6, 761-766 (2005).
-
Kappes, D.J. & He, X. CD4-CD8 lineage commitment: An inside view. Nat. Immunol. 6, 761-766 (2005).
-
-
-
-
10
-
-
2942620983
-
Illuminating autoimmune regulators through controlled variation of the mouse genome sequence
-
Vinuesa, C.G. & Goodnow, C.C. Illuminating autoimmune regulators through controlled variation of the mouse genome sequence. Immunity 20 669-679 (2004).
-
(2004)
Immunity
, vol.20
, pp. 669-679
-
-
Vinuesa, C.G.1
Goodnow, C.C.2
-
11
-
-
0034698734
-
Premature expression of T cell receptor (TCR)αβ suppresses TCRγδ gene rearrangement but permits development of δγ lineage T cells
-
Terrence, K., Pavlovich, C.P., Matechak, E.O. & Fowlkes, B.J. Premature expression of T cell receptor (TCR)αβ suppresses TCRγδ gene rearrangement but permits development of δγ lineage T cells. J. Exp. Med. 192, 537-548 (2000).
-
(2000)
J. Exp. Med
, vol.192
, pp. 537-548
-
-
Terrence, K.1
Pavlovich, C.P.2
Matechak, E.O.3
Fowlkes, B.J.4
-
14
-
-
0025022278
-
Requirement for cotolerogenic gene products in the clonal deletion of I-E reactive T cells
-
Woodland, D., Happ, M.P., Bill, J. & Palmer, E. Requirement for cotolerogenic gene products in the clonal deletion of I-E reactive T cells. Science 247, 964-967 (1990).
-
(1990)
Science
, vol.247
, pp. 964-967
-
-
Woodland, D.1
Happ, M.P.2
Bill, J.3
Palmer, E.4
-
15
-
-
33748325753
-
ENU-mutagenesis: Insight into immune function and pathology
-
Cook, M.C., Vinuesa, C.G. & Goodnow, C.C. ENU-mutagenesis: Insight into immune function and pathology. Curr. Opin. Immunol. 18, 627-633 (2006).
-
(2006)
Curr. Opin. Immunol
, vol.18
, pp. 627-633
-
-
Cook, M.C.1
Vinuesa, C.G.2
Goodnow, C.C.3
-
16
-
-
67651166585
-
-
Lesourne, R. Themis, a T cell-specific protein important for late thymocyte development Nat. Immunol. advance online publication doi:10.1038/ni1768 (13 July 2009).
-
Lesourne, R. Themis, a T cell-specific protein important for late thymocyte development Nat. Immunol. advance online publication doi:10.1038/ni1768 (13 July 2009).
-
-
-
-
17
-
-
67651154100
-
-
Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling, advance online publication doi:10.1038/ni1766 13 July
-
Fu, G. et al. Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling. Nat. Immunol. advance online publication doi:10.1038/ni1766 (13 July 2009).
-
(2009)
Nat. Immunol
-
-
Fu, G.1
-
18
-
-
27544481941
-
A function for interleukin 2 in Foxp3-expressing regulatory T cells
-
Fontenot, J.D., Rasmussen, J.P., Gavin, M.A. & Rudensky, A.Y. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat. Immunol. 6, 1142-1151 (2005).
-
(2005)
Nat. Immunol
, vol.6
, pp. 1142-1151
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Gavin, M.A.3
Rudensky, A.Y.4
-
19
-
-
36048978911
-
Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature
-
Hill, J.A. et al. Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. Immunity 27, 786-800 (2007).
-
(2007)
Immunity
, vol.27
, pp. 786-800
-
-
Hill, J.A.1
-
20
-
-
33847242598
-
Foxp3 occupancy and regulation of key target genes during T-cell stimulation
-
Marson, A. et al. Foxp3 occupancy and regulation of key target genes during T-cell stimulation. Nature 445, 931-935 (2007).
-
(2007)
Nature
, vol.445
, pp. 931-935
-
-
Marson, A.1
-
21
-
-
0036604986
-
Scaffolds, adaptors and linkers of TCR signaling: Theory and practice
-
Burack, W.R., Cheng, A.M. & Shaw, A.S. Scaffolds, adaptors and linkers of TCR signaling: Theory and practice. Curr. Opin. Immunol. 14 312-316 (2002).
-
(2002)
Curr. Opin. Immunol
, vol.14
, pp. 312-316
-
-
Burack, W.R.1
Cheng, A.M.2
Shaw, A.S.3
-
22
-
-
0033555070
-
Focal adhesion kinase in integrin-mediated signaling
-
Cary, L.A. & Guan, J.L. Focal adhesion kinase in integrin-mediated signaling. Front. Biosci. 4, D102-D113 (1999).
-
(1999)
Front. Biosci
, vol.4
-
-
Cary, L.A.1
Guan, J.L.2
-
23
-
-
0028694342
-
Activation of Ras by receptor tyrosine kinases
-
Margolis, B. & Skolnik, E.Y. Activation of Ras by receptor tyrosine kinases. J. Am. Soc. Nephrol. 5, 1288-1299 (1994).
-
(1994)
J. Am. Soc. Nephrol
, vol.5
, pp. 1288-1299
-
-
Margolis, B.1
Skolnik, E.Y.2
-
25
-
-
16244418695
-
Genetic lesions in T-cell tolerance and thresholds for autoimmunity
-
Liston, A., Lesage, S., Gray, D.H., Boyd, R.L. & Goodnow, C.C. Genetic lesions in T-cell tolerance and thresholds for autoimmunity. Immunol. Rev. 204, 87-101 (2005).
-
(2005)
Immunol. Rev
, vol.204
, pp. 87-101
-
-
Liston, A.1
Lesage, S.2
Gray, D.H.3
Boyd, R.L.4
Goodnow, C.C.5
-
26
-
-
42249099071
-
B-Raf-mediated signaling pathway regulates T cell development
-
Tsukamoto, H. et al. B-Raf-mediated signaling pathway regulates T cell development. Eur. J. Immunol. 38, 518-527 (2008).
-
(2008)
Eur. J. Immunol
, vol.38
, pp. 518-527
-
-
Tsukamoto, H.1
-
27
-
-
0034712755
-
Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes
-
Geiman, T.M. & Muegge, K. Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes. Proc. Natl. Acad. Sci. USA 97, 4772-4777 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4772-4777
-
-
Geiman, T.M.1
Muegge, K.2
-
28
-
-
10744219638
-
Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death
-
Okada, H. et al. Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death. J. Exp. Med. 199 399-410 (2004).
-
(2004)
J. Exp. Med
, vol.199
, pp. 399-410
-
-
Okada, H.1
-
29
-
-
0347915639
-
Essential role of survivin, an inhibitor of apoptosis protein, in T cell development, maturation, and homeostasis
-
Xing, Z., Conway, E.M., Kang, C. & Winoto, A. Essential role of survivin, an inhibitor of apoptosis protein, in T cell development, maturation, and homeostasis. J. Exp. Med. 199, 69-80 (2004).
-
(2004)
J. Exp. Med
, vol.199
, pp. 69-80
-
-
Xing, Z.1
Conway, E.M.2
Kang, C.3
Winoto, A.4
-
30
-
-
46149098344
-
LXR signaling couples sterol metabolism to proliferation in the acquired immune response
-
Bensinger, S.J. et al. LXR signaling couples sterol metabolism to proliferation in the acquired immune response. Cell 134, 97-111 (2008).
-
(2008)
Cell
, vol.134
, pp. 97-111
-
-
Bensinger, S.J.1
-
31
-
-
36749003787
-
Calcineurin sets the bandwidth for discrimination of signals during thymocyte development
-
Gallo, E.M. et al. Calcineurin sets the bandwidth for discrimination of signals during thymocyte development. Nature 450, 731-735 (2007).
-
(2007)
Nature
, vol.450
, pp. 731-735
-
-
Gallo, E.M.1
-
33
-
-
34248224562
-
Maturational arrest of thymocyte development is caused by a deletion in the receptor-like protein tyrosine phosphatase κ gene in LEC rats
-
Kose, H. et al. Maturational arrest of thymocyte development is caused by a deletion in the receptor-like protein tyrosine phosphatase κ gene in LEC rats. Genomics 89, 673-677 (2007).
-
(2007)
Genomics
, vol.89
, pp. 673-677
-
-
Kose, H.1
-
34
-
-
36348963611
-
A deletion mutation of the protein tyrosine phosphatase κ (Ptprk) gene is responsible for T-helper immunodeficiency (thid) in the LEC rat
-
Asano, A., Tsubomatsu, K., Jung, C.G., Sasaki, N. & Agui, T. A deletion mutation of the protein tyrosine phosphatase κ (Ptprk) gene is responsible for T-helper immunodeficiency (thid) in the LEC rat. Mamm. Genome 18, 779-786 (2007).
-
(2007)
Mamm. Genome
, vol.18
, pp. 779-786
-
-
Asano, A.1
Tsubomatsu, K.2
Jung, C.G.3
Sasaki, N.4
Agui, T.5
-
35
-
-
38049105629
-
Down-regulation of the TGF-β target gene, PTPRK, by the Epstein-Barr virus encoded EBNA1 contributes to the growth and survival of Hodgkin lymphoma cells
-
Flavell, J.R. et al. Down-regulation of the TGF-β target gene, PTPRK, by the Epstein-Barr virus encoded EBNA1 contributes to the growth and survival of Hodgkin lymphoma cells. Blood 111, 292-301 (2008).
-
(2008)
Blood
, vol.111
, pp. 292-301
-
-
Flavell, J.R.1
-
36
-
-
0037442987
-
Novel tumor suppressor loci on 6q22-23 in primary central nervous system lymphomas
-
Nakamura, M. et al. Novel tumor suppressor loci on 6q22-23 in primary central nervous system lymphomas. Cancer Res. 63, 737-741 (2003).
-
(2003)
Cancer Res
, vol.63
, pp. 737-741
-
-
Nakamura, M.1
-
37
-
-
18944382074
-
Transforming growth factor β (TGF-β)-Smad target gene protein tyrosine phosphatase receptor type κ is required for TGF-β function
-
Wang, S.E., Wu, F.Y., Shin, I., Qu, S. & Arteaga, C.L. Transforming growth factor β (TGF-β)-Smad target gene protein tyrosine phosphatase receptor type κ is required for TGF-β function. Mol. Cell. Biol. 25, 4703-4715 (2005).
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 4703-4715
-
-
Wang, S.E.1
Wu, F.Y.2
Shin, I.3
Qu, S.4
Arteaga, C.L.5
-
38
-
-
0030597284
-
Transforming growth factor-β1 inhibits human keratinocyte proliferation by upregulation of a receptor-type tyrosine phosphatase R-PTP-κ gene expression
-
Yang, Y. et al. Transforming growth factor-β1 inhibits human keratinocyte proliferation by upregulation of a receptor-type tyrosine phosphatase R-PTP-κ gene expression. Biochem. Biophys. Res. Commun. 228, 807-812 (1996).
-
(1996)
Biochem. Biophys. Res. Commun
, vol.228
, pp. 807-812
-
-
Yang, Y.1
-
39
-
-
0036286741
-
Detection of increased icb-1 transcript levels in maturing HL-60 cells: A novel marker for granulocytic and monocytic in vitro differentiation
-
Treeck, O. et al. Detection of increased icb-1 transcript levels in maturing HL-60 cells: A novel marker for granulocytic and monocytic in vitro differentiation. Leuk. Res. 26, 765-769 (2002).
-
(2002)
Leuk. Res
, vol.26
, pp. 765-769
-
-
Treeck, O.1
-
40
-
-
27944453013
-
Expression of Icb-1 gene is interferon-γ inducible in breast and ovarian cancer cell lines and affects the IFN γ-response of SK-OV-3 ovarian cancer cells
-
Treeck, O., Kindzorra, I., Pauser, K., Treeck, L. & Ortmann, O. Expression of Icb-1 gene is interferon-γ inducible in breast and ovarian cancer cell lines and affects the IFN γ-response of SK-OV-3 ovarian cancer cells. Cytokine 32, 137-142 (2005).
-
(2005)
Cytokine
, vol.32
, pp. 137-142
-
-
Treeck, O.1
Kindzorra, I.2
Pauser, K.3
Treeck, L.4
Ortmann, O.5
-
41
-
-
0037827638
-
Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis
-
Jun, J.E. et al. Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis. Immunity 18, 751-762 (2003).
-
(2003)
Immunity
, vol.18
, pp. 751-762
-
-
Jun, J.E.1
-
43
-
-
0035881574
-
+ T cells in vivo: Multiple thresholds in response to a constant level of antigen presentation
-
+ T cells in vivo: Multiple thresholds in response to a constant level of antigen presentation. J. Immunol. 167, 2030-2039 (2001).
-
(2001)
J. Immunol
, vol.167
, pp. 2030-2039
-
-
Tanchot, C.1
Barber, D.L.2
Chiodetti, L.3
Schwartz, R.H.4
-
44
-
-
0025933951
-
Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice
-
Huesmann, M., Scott, B., Kisielow, P. & von Boehmer, H. Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice. Cell 66, 533-540 (1991).
-
(1991)
Cell
, vol.66
, pp. 533-540
-
-
Huesmann, M.1
Scott, B.2
Kisielow, P.3
von Boehmer, H.4
-
45
-
-
35348877956
-
MyD88-dependent autoimmune disease in Lyn-deficient mice
-
Silver, K.L. et al. MyD88-dependent autoimmune disease in Lyn-deficient mice. Eur. J. Immunol. 37, 2734-2743 (2007).
-
(2007)
Eur. J. Immunol
, vol.37
, pp. 2734-2743
-
-
Silver, K.L.1
-
46
-
-
0032055828
-
Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signalling and selection
-
Cornall, R.J. et al. Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signalling and selection. Immunity 8, 497-508 (1998).
-
(1998)
Immunity
, vol.8
, pp. 497-508
-
-
Cornall, R.J.1
-
47
-
-
36248944103
-
Ribosomal protein S3: A KH domain subunit in NF-κB complexes that mediates selective gene regulation
-
Wan, F. et al. Ribosomal protein S3: A KH domain subunit in NF-κB complexes that mediates selective gene regulation. Cell 131, 927-939 (2007).
-
(2007)
Cell
, vol.131
, pp. 927-939
-
-
Wan, F.1
-
48
-
-
12344298241
-
Active mixing during hybridization improves the accuracy and reproducibility of microarray results
-
Schaupp, C.J., Jiang, G., Myers, T.G. & Wilson, M.A. Active mixing during hybridization improves the accuracy and reproducibility of microarray results. Biotechniques 38, 117-119 (2005).
-
(2005)
Biotechniques
, vol.38
, pp. 117-119
-
-
Schaupp, C.J.1
Jiang, G.2
Myers, T.G.3
Wilson, M.A.4
-
49
-
-
0037311919
-
TM4: A free, open-source system for microarray data management and analysis
-
Saeed, A.I. et al. TM4: A free, open-source system for microarray data management and analysis. Biotechniques 34, 374-378 (2003).
-
(2003)
Biotechniques
, vol.34
, pp. 374-378
-
-
Saeed, A.I.1
|