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Volumn 2014, Issue , 2014, Pages

Human AP Endonuclease 1: A potential marker for the prediction of environmental carcinogenesis risk

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; GENES; HEAVY METALS; IONIZING RADIATION; PATHOLOGY; TRANSCRIPTION;

EID: 84930808429     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2014/730301     Document Type: Review
Times cited : (19)

References (188)
  • 1
    • 78149471195 scopus 로고    scopus 로고
    • Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment
    • G. Tell, D. Fantini, and F. Quadrifoglio, " Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment," Cellular and Molecular Life Sciences, vol. 67, no. 21, pp. 3589-3608, 2010.
    • (2010) Cellular and Molecular Life Sciences , vol.67 , Issue.21 , pp. 3589-3608
    • Tell, G.1    Fantini, D.2    Quadrifoglio, F.3
  • 3
    • 51349134457 scopus 로고    scopus 로고
    • Role of themultifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: Small-molecule inhibition of the redox function of Ape1, "
    • M. Luo, S.Delaplane,A. Jiang et al., " Role of themultifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1, " Antioxidants and Redox Signaling, vol. 10, no. 11, pp. 1853-1867, 2008.
    • (2008) Antioxidants and Redox Signaling , vol.10 , Issue.11 , pp. 1853-1867
    • Luo, M.1    Delaplane, S.2    Jiang, A.3
  • 4
    • 33846976720 scopus 로고    scopus 로고
    • A dominant-negative formof themajor human abasic endonuclease enhances cellular sensitivity to laboratory and clinical DNA-damaging agents
    • D. R. McNeill and D. M. Wilson III, " A dominant-negative formof themajor human abasic endonuclease enhances cellular sensitivity to laboratory and clinical DNA-damaging agents," Molecular Cancer Research, vol. 5, no. 1, pp. 61-70, 2007.
    • (2007) Molecular Cancer Research , vol.5 , Issue.1 , pp. 61-70
    • McNeill, D.R.1    Wilson, D.M.2
  • 7
    • 78650501028 scopus 로고    scopus 로고
    • Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions
    • D. Fantini, C. Vascotto, D. Marasco et al., " Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions, " Nucleic Acids Research, vol. 38, no. 22, pp. 8239-8256, 2010.
    • (2010) Nucleic Acids Research , vol.38 , Issue.22 , pp. 8239-8256
    • Fantini, D.1    Vascotto, C.2    Marasco, D.3
  • 8
    • 79960099275 scopus 로고    scopus 로고
    • The protective role ofNrf2 incadmiuminduced DNA damage, "
    • J. Y. Park andY.R. Seo, "The protective role ofNrf2 incadmiuminduced DNA damage, " Molecular and Cellular Toxicology, vol. 7, no. 1, pp. 61-66, 2011.
    • (2011) Molecular and Cellular Toxicology , vol.7 , Issue.1 , pp. 61-66
    • Park, J.Y.1    Seo, Y.R.2
  • 9
    • 84863011154 scopus 로고    scopus 로고
    • Synergistic genotoxic effect between gene and environmental pollutant: Oxidative DNA damage induced by thioredoxin reductase 1 silencing under nickel treatment
    • H. L. Kim and Y. R. Seo, " Synergistic genotoxic effect between gene and environmental pollutant: oxidative DNA damage induced by thioredoxin reductase 1 silencing under nickel treatment, " Molecular and Cellular Toxicology, vol. 7, no. 3, pp. 251-257, 2011.
    • (2011) Molecular and Cellular Toxicology , vol.7 , Issue.3 , pp. 251-257
    • Kim, H.L.1    Seo, Y.R.2
  • 10
    • 84874072268 scopus 로고    scopus 로고
    • Protective role of thioredoxin reductase 1 in cadmium-induced DNA damage
    • J. Y. Park, Y. J. Lee, P. Koedrith, and Y. R. Seo, " Protective role of thioredoxin reductase 1 in cadmium-induced DNA damage," Molecular and Cellular Toxicology, vol. 8, no. 3, pp. 289-295, 2012.
    • (2012) Molecular and Cellular Toxicology , vol.8 , Issue.3 , pp. 289-295
    • Park, J.Y.1    Lee, Y.J.2    Koedrith, P.3    Seo, Y.R.4
  • 11
    • 84868103413 scopus 로고    scopus 로고
    • Molecular and genomic approach for understanding the gene-environment interaction between Nrf2 defciency and carcinogenic nickel-inducedDNA damage, "
    • H. L. Kim and Y. R. Seo, " Molecular and genomic approach for understanding the gene-environment interaction between Nrf2 defciency and carcinogenic nickel-inducedDNA damage, " Oncology Reports, vol. 28, no. 6, pp. 1959-1967, 2012.
    • (2012) Oncology Reports , vol.28 , Issue.6 , pp. 1959-1967
    • Kim, H.L.1    Seo, Y.R.2
  • 12
    • 0035815108 scopus 로고    scopus 로고
    • Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: Implications for the catalytic mechanism, "
    • P. T. Beernink,B.W. SegelkeM. Z.Hadi,J. P. Erzberger,D. M. Wilson III,B. Rupp Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism, " Journal ofMolecular Biology 307, 4, 1023- 1034, 2001.
    • (2001) Journal OfMolecular Biology , vol.307 , Issue.4 , pp. 1023-1034
    • Beernink, P.T.1    Segelkem, Z.2    Hadi, B.W.3    Erzberger, J.P.4    Wilson, D.M.5    Rupp, B.6
  • 13
    • 84892927300 scopus 로고    scopus 로고
    • Human apurinic/apyrimidinic endonuclease 1
    • M. X. Li and D. M. Wilson, "Human apurinic/apyrimidinic endonuclease 1, " Antioxidants & Redox Signaling, vol. 20, no. 4, pp. 678-707, 2014.
    • (2014) Antioxidants & Redox Signaling , vol.20 , Issue.4 , pp. 678-707
    • Li, M.X.1    Wilson, D.M.2
  • 17
    • 1842735418 scopus 로고    scopus 로고
    • Human AP endonuclease (APE1) demonstrates endonucleolytic activity against AP sites in single-stranded DNA
    • D. R.Marenstein, D. M.Wilson III, and G.W. Teebor, " Human AP endonuclease (APE1) demonstrates endonucleolytic activity against AP sites in single-stranded DNA," DNA Repair, vol. 3, no. 5, pp. 527-533, 2004.
    • (2004) DNA Repair , vol.3 , Issue.5 , pp. 527-533
    • Marenstein, D.R.1    Wilson, D.M.2    Teebor, G.W.3
  • 18
    • 0035837587 scopus 로고    scopus 로고
    • The major human abasic endonuclease: Formation, consequences and repair of abasic lesions in DNA
    • D. M. Wilson III and D. Barsky, " The major human abasic endonuclease: Formation, consequences and repair of abasic lesions in DNA," Mutation Research/DNA Repair, vol. 485, no. 4, pp. 283-307, 2001.
    • (2001) Mutation Research/DNA Repair , vol.485 , Issue.4 , pp. 283-307
    • Wilson, D.M.1    Barsky, D.2
  • 19
    • 0023015325 scopus 로고
    • Mutagenesis by apurinic/apyrimidinic sites
    • L. A. Loeb and B. D. Preston, "Mutagenesis by apurinic/apyrimidinic sites, " Annual Review of Genetics, vol. 20, pp. 201-230, 1986.
    • (1986) Annual Review of Genetics , vol.20 , pp. 201-230
    • Loeb, L.A.1    Preston, B.D.2
  • 21
    • 0028245076 scopus 로고
    • Removal of 3-phosphoglycolate from DNA strand-break damage in an oligonucleotide substrate by recombinant human apurinic/apyrimidinic endonuclease 1
    • T. A. Winters, W. D. Henner, P. S. Russell, A. McCullough, and T. J. Jorgensen, " Removal of 3-phosphoglycolate from DNA strand-break damage in an oligonucleotide substrate by recombinant human apurinic/apyrimidinic endonuclease 1, " Nucleic Acids Research, vol. 22, no. 10, pp. 1866-1873, 1994.
    • (1994) Nucleic Acids Research , vol.22 , Issue.10 , pp. 1866-1873
    • Winters, T.A.1    Henner, W.D.2    Russell, P.S.3    McCullough, A.4    Jorgensen, T.J.5
  • 23
    • 0030788621 scopus 로고    scopus 로고
    • endonuclease at DNA double-strand break ends," Nucleic Acids Research, vol. 25, no. 12, pp. 2495-2500, 1997.
    • (1997) Nucleic Acids Research , vol.25 , Issue.12 , pp. 2495-2500
  • 24
    • 0029128447 scopus 로고
    • Identification of critical active-site residues in the multifunctional human DNA repair enzymeHAP1, "
    • G. Barzilay, C. D. Mol, C. N. Robson et al., " Identification of critical active-site residues in the multifunctional human DNA repair enzymeHAP1, " Nature Structural Biology, vol. 2, no. 7, pp. 561-568, 1995.
    • (1995) Nature Structural Biology , vol.2 , Issue.7 , pp. 561-568
    • Barzilay, G.1    Mol, C.D.2    Robson, C.N.3
  • 25
    • 0029001186 scopus 로고
    • Incision activity of human apurinic endonuclease (Ape) at abasic site analogs inDNA
    • D. M.Wilson III, M. Takeshita, A. P. Grollman, and B. Demple, " Incision activity of human apurinic endonuclease (Ape) at abasic site analogs inDNA," Journal of Biological Chemistry, vol. 270, no. 27, pp. 16002-16007, 1995.
    • (1995) Journal of Biological Chemistry , vol.270 , Issue.27 , pp. 16002-16007
    • Wilson, D.M.1    Takeshita, M.2    Grollman, A.P.3    Demple, B.4
  • 26
    • 0026004662 scopus 로고
    • Two distinct human DNA diesterases that hydrolyze 3-blocking deoxyribose fragments from oxidized DNA
    • D. S. Chen, T. Herman, and B. Demple, " Two distinct human DNA diesterases that hydrolyze 3-blocking deoxyribose fragments from oxidized DNA," Nucleic Acids Research, vol. 19, no. 21, pp. 5907-5914, 1991.
    • (1991) Nucleic Acids Research , vol.19 , Issue.21 , pp. 5907-5914
    • Chen, D.S.1    Herman, T.2    Demple, B.3
  • 27
    • 0028342951 scopus 로고
    • Repair of oxidative damage to DNA: Enzymology and biology
    • B. Demple and L. Harrison, "Repair of oxidative damage to DNA: enzymology and biology, " Annual Reviewof Biochemistry, vol. 63, pp. 915-948, 1994.
    • (1994) Annual Reviewof Biochemistry , vol.63 , pp. 915-948
    • Demple, B.1    Harrison, L.2
  • 28
    • 3242710517 scopus 로고    scopus 로고
    • AP endonucleaseindependent DNA base excision repair in human cells
    • L.Wiederhold, J. B. Leppard, P. Kedar et al., " AP endonucleaseindependent DNA base excision repair in human cells," Molecular Cell, vol. 15, no. 2, pp. 209-220, 2004.
    • (2004) Molecular Cell , vol.15 , Issue.2 , pp. 209-220
    • Wiederhold, L.1    Leppard, J.B.2    Kedar, P.3
  • 29
    • 0242268065 scopus 로고    scopus 로고
    • Mammalian DNA base excision repair proteins: Their interactions and role in repair of oxidative DNA damage
    • T. Izumi, L. R. Wiederhold, G. Roy et al., " Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damage," Toxicology, vol. 193, no. 1- 2, pp. 43-65, 2003. [29] D. M. Flaherty, M. M. Monick, A. B. Carter, M. W. Peterson, and G.W.Hunninghake, " Oxidant-mediated increases in redox factor-1 nuclear protein and activator protein-1 DNA binding in asbestos-treated macrophages, " Journal of Immunology, vol. 168, no. 11, pp. 5675-5681, 2002.
    • (2003) Toxicology , vol.193 , Issue.1-2 , pp. 43-65
    • Izumi, T.1    Wiederhold, L.R.2    Roy, G.3
  • 30
    • 0036604453 scopus 로고    scopus 로고
    • Oxidant-mediated increases in redox factor-1 nuclear protein and activator protein-1 DNA binding in asbestos-treated macrophages
    • D. M. Flaherty, M. M. Monick, A. B. Carter, M. W. Peterson, and G.W.Hunninghake, " Oxidant-mediated increases in redox factor-1 nuclear protein and activator protein-1 DNA binding in asbestos-treated macrophages, " Journal of Immunology, vol. 168, no. 11, pp. 5675-5681, 2002
    • (2002) Journal of Immunology , vol.168 , Issue.11 , pp. 5675-5681
    • Flaherty, D.M.1    Monick, M.M.2    Carter, A.B.3    Peterson, M.W.4    Hunninghake, G.W.5
  • 31
    • 0037162995 scopus 로고    scopus 로고
    • Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions, "
    • T. K. Hazra, Y. W. Kow, Z. Hatahet et al., " Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions, "The Journal of Biological Chemistry, vol. 277, no. 34, pp. 30417-30420, 2002.
    • (2002) The Journal of Biological Chemistry , vol.277 , Issue.34 , pp. 30417-30420
    • Hazra, T.K.1    Kow, Y.W.2    Hatahet, Z.3
  • 32
    • 14044269479 scopus 로고    scopus 로고
    • The intracellular loc alization of APE1/Ref-1: More than a passive phenomenon
    • G. Tell, G. Damante, D. Caldwell, and M. R. Kelley, "The intracellular loc alization of APE1/Ref-1: more than a passive phenomenon?" Antioxidants and Redox Signaling, vol. 7, no. 3- 4, pp. 367-384, 2005.
    • (2005) Antioxidants and Redox Signaling , vol.7 , Issue.3-4 , pp. 367-384
    • Tell, G.1    Damante, G.2    Caldwell, D.3    Kelley, M.R.4
  • 33
    • 0035940441 scopus 로고    scopus 로고
    • Interactio n of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair
    • I. I. Dianova, V. A. Bohr, and G. L. Dianov, "Interactio n of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair," Biochemistry, vol. 40, no. 42, pp. 12639-12644, 2001.
    • (2001) Biochemistry , vol.40 , Issue.42 , pp. 12639-12644
    • Dianova, I.I.1    Bohr, V.A.2    Dianov, G.L.3
  • 34
    • 0032502675 scopus 로고    scopus 로고
    • Involvement of flap endonuclease 1 in base excision DNA repair
    • K. Kim S. Biade, Y. Matsumoto Involvement of flap endonuclease 1 in base excision DNA repair The Journal of Biological Chemistry 273 ,15 ,8842-8848, 1998.
    • (1998) The Journal of Biological Chemistry , vol.273 , Issue.15 , pp. 8842-8848
    • Kim, K.1    Biade, S.2    Matsumoto, Y.3
  • 35
    • 0030957997 scopus 로고    scopus 로고
    • Second pathway for completion of human DNA base excision-repair: Reconstitution with purified proteins and requirement forDNase IV(FEN1)
    • A. Klungland and T. Lindahl, " Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement forDNase IV(FEN1)," TheEMBO Journal, vol. 16, no. 11, pp. 3341-3348, 1997.
    • (1997) TheEMBO Journal , vol.16 , Issue.11 , pp. 3341-3348
    • Klungl, A.1    Lindahl, T.2
  • 36
    • 36749082147 scopus 로고    scopus 로고
    • Base excisionDNArepair defect in Gadd45a-deficient cells
    • H. J. Jung, E.H. Kim, J.-Y.Mun et al., " Base excisionDNArepair defect in Gadd45a-deficient cells," Oncogene, vol. 26, no. 54, pp. 7517-7525, 2007.
    • (2007) Oncogene , vol.26 , Issue.54 , pp. 7517-7525
    • Jung, H.J.1    Kim, E.H.2    Mun, J.-Y.3
  • 37
    • 84877071859 scopus 로고    scopus 로고
    • A novel role for Gadd45 in base excision repair: Modulation of APE1 activity by the direct interaction of Gadd45 with PCNA
    • H. L. Kim, S. U. Kim , and Y. R. Seo, " A novel role for Gadd45 in base excision repair: modulation of APE1 activity by the direct interaction of Gadd45 with PCNA," Biochemical and Biophysical Research Communications, vol. 434, no. 2, pp. 185-190, 2013.
    • (2013) Biochemical and Biophysical Research Communications , vol.434 , Issue.2 , pp. 185-190
    • Kim, H.L.1    Kim, S.U.2    Seo, Y.R.3
  • 38
    • 84882583476 scopus 로고    scopus 로고
    • A novel chemopreventive mechanism of selenomethionine: Enhancement of APE1 enzyme activity via a Gadd45a, PCNA and APE1 protein complex that regulates p53-mediated base excision repair
    • H. J. Jung, H. L. Kim, Y. J. Kim, J. Weon, and Y. R. Seo, " A novel chemopreventive mechanism of selenomethionine: enhancement of APE1 enzyme activity via a Gadd45a, PCNA and APE1 protein complex that regulates p53-mediated base excision repair, " Oncology Reports, vol. 30, no. 4, pp. 1581-1586, 2013.
    • (2013) Oncology Reports , vol.30 , Issue.4 , pp. 1581-1586
    • Jung, H.J.1    Kim, H.L.2    Kim, Y.J.3    Weon, J.4    Seo, Y.R.5
  • 39
    • 0037428228 scopus 로고    scopus 로고
    • DNAsingle-strand break repair and spinocerebellar ataxia
    • K.W. Caldecott, "DNAsingle-strand break repair and spinocerebellar ataxia, " Cell, vol. 112, no. 1, pp. 7-10, 2003.
    • (2003) Cell , vol.112 , Issue.1 , pp. 7-10
    • Caldecott, K.W.1
  • 40
    • 0033976049 scopus 로고    scopus 로고
    • A cell cycle-specific requirement for the XRCC1 BRCT II domain during mammalian DNA strand break repair, "
    • R. M. Taylor, D. J. Moore, J. Whitehouse, P. Johnson, and K. W. Caldecott, " A cell cycle-specific requirement for the XRCC1 BRCT II domain during mammalian DNA strand break repair, " Molecular and Cellular Biology, vol. 20,no. 2, pp. 735-740, 2000.
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.2 , pp. 735-740
    • Taylor, R.M.1    Moore, D.J.2    Whitehouse, J.3    Johnson, P.4    Caldecott, K.W.5
  • 41
    • 0035890069 scopus 로고    scopus 로고
    • XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions, "
    • A. E.Vidal, S. Boiteux, I.D.Hickson, and J. P. Radicella, " XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions, " The EMBO Journal, vol. 20, no. 22, pp. 6530-6539, 2001.
    • (2001) The EMBO Journal , vol.20 , Issue.22 , pp. 6530-6539
    • Vidal, A.E.1    Boiteux, S.2    Hickson, I.D.3    Radicella, J.P.4
  • 42
    • 0034733644 scopus 로고    scopus 로고
    • Natural resistance of human beta cells toward nitric oxide is mediated by heat shock protein 70
    • V. Burkart, H. Liu, K. Bellmann et al., " Natural resistance of human beta cells toward nitric oxide is mediated by heat shock protein 70," Journal of Biological Chemistry, vol. 275, no. 26, pp. 19521-19528, 2000.
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.26 , pp. 19521-19528
    • Burkart, V.1    Liu, H.2    Bellmann, K.3
  • 44
    • 0035937744 scopus 로고    scopus 로고
    • Heat shock protein 70 binds to human apurinic/apyrimidinic endonuclease and stimulates endonuclease activity at abasic sites
    • M. K. Kenny, F. Mendez, M. Sandigursky et al., " Heat shock protein 70 binds to human apurinic/apyrimidinic endonuclease and stimulates endonuclease activity at abasic sites, " Journal of Biological Chemistry, vol. 276, no. 12, pp. 9532-9536, 2001.
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.12 , pp. 9532-9536
    • Kenny, M.K.1    Mendez, F.2    Sandigursky, M.3
  • 45
    • 0037354871 scopus 로고    scopus 로고
    • Specific stimulation of human apurinic/apyrimidinic endonuclease by heat shock protein 70
    • F. Mendez, M. Sandigursky, R. P. Kureekattil, M. K. Kenny, W. A. Franklin, and R. Bases, " Specific stimulation of human apurinic/apyrimidinic endonuclease by heat shock protein 70, " DNA Repair, vol. 2, no. 3, pp. 259-271, 2003.
    • (2003) DNA Repair , vol.2 , Issue.3 , pp. 259-271
    • Mendez, F.1    Sandigursky, M.2    Kureekattil, R.P.3    Kenny, M.K.4    Franklin, W.A.5    Bases, R.6
  • 46
    • 0034866372 scopus 로고    scopus 로고
    • Redox regulation of the DNA repair function of the human AP endonuclease Ape1/ref-1
    • M. R. Kelley and S. H. Parsons, "Redox regulation of the DNA repair function of the human AP endonuclease Ape1/ref-1, " Antioxidants and Redox Signaling, vol. 3, no. 4, pp. 671-683, 2001.
    • (2001) Antioxidants and Redox Signaling , vol.3 , Issue.4 , pp. 671-683
    • Kelley, M.R.1    Parsons, S.H.2
  • 47
    • 84855822330 scopus 로고    scopus 로고
    • APE1/Ref-1role in redox signaling: Translational applications of targ eting the redox function of the DNA repair/redox protein APE1/Ref-1
    • M. R. Kelley, M. M. Georgiadis, and M. L. Fishel, "APE1/Ref-1role in redox signaling: translational applications of targ eting the redox function of the DNA repair/redox protein APE1/Ref-1," CurrentMolecular Pharmacology, vol. 5, no. 1,pp. 36-53, 2012.
    • (2012) CurrentMolecular Pharmacology , vol.5 , Issue.1 , pp. 36-53
    • Kelley, M.R.1    Georgiadis, M.M.2    Fishel, M.L.3
  • 49
    • 0027324056 scopus 로고
    • Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding
    • L. J. Walker, C. N. Robson, E. Black, D. Gillespie, and I. D. Hickson, " Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding, " Molecular and Cellular Biology, vol. 13, no. 9, pp. 5370-5376, 1993.
    • (1993) Molecular and Cellular Biology , vol.13 , Issue.9 , pp. 5370-5376
    • Walker, L.J.1    Robson, C.N.2    Black, E.3    Gillespie, D.4    Hickson, I.D.5
  • 50
    • 0034719372 scopus 로고    scopus 로고
    • DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination
    • C. D. Mol, T. Izumi, S. Mitra, and J. A. Talner, "DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination," Nature, vol. 403, no. 6768, pp. 451-456, 2000.
    • (2000) Nature , vol.403 , Issue.6768 , pp. 451-456
    • Mol, C.D.1    Izumi, T.2    Mitra, S.3    Talner, J.A.4
  • 51
    • 84862924317 scopus 로고    scopus 로고
    • Characterization of the redox activity and disulfide bond formation in apurinic/apyrimidinic endonuclease
    • M. H. Luo, J. Zhang, H. Z. He et al., " Characterization of the redox activity and disulfide bond formation in apurinic/apyrimidinic endonuclease, " Biochemistry, vol. 51, no. 2, pp. 695-705, 2012.
    • (2012) Biochemistry , vol.51 , Issue.2 , pp. 695-705
    • Luo, M.H.1    Zhang, J.2    He, H.Z.3
  • 52
    • 0026583944 scopus 로고
    • Identification and characterization of Ref-1, a nuclear protein that fac ilitates AP-1 DNAbinding activity
    • S. Xanthoudakis and T. Curran, "Identification and characterization of Ref-1, a nuclear protein that fac ilitates AP-1 DNAbinding activity," The EMBO Journal, vol. 11, no. 2, pp. 653-665, 1992.
    • (1992) The EMBO Journal , vol.11 , Issue.2 , pp. 653-665
    • Xanthoudakis, S.1    Curran, T.2
  • 53
    • 0036399525 scopus 로고    scopus 로고
    • Oxidoreductive modification of two cysteine residues in paired domain by Ref-1 regulates DNA-binding activity of Pax-8
    • X. Cao, F. Kambe, S. Ohmori, and H. Seo, " Oxidoreductive modification of two cysteine residues in paired domain by Ref-1 regulates DNA-binding activity of Pax-8, " Biochemical and Biophysical Research Communications ,297 ,2,288-293,2002.
    • (2002) Biochemical and Biophysical Research Communications , vol.297 , Issue.2 , pp. 288-293
    • Cao, X.1    Kambe, F.2    Ohmori, S.3    Seo, H.4
  • 54
    • 0033118983 scopus 로고    scopus 로고
    • Molecular mechanisms of transcription activation by HLF and HIF1 in response to hypoxia: Their stabilization and redox signal-induced interaction with CBP/p300, "
    • M. Ema, K. Hirota, J. Mimura et al., " Molecular mechanisms of transcription activation by HLF and HIF1 in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300, "TheEMBOJournal, vol. 18,no. 7, pp. 1905-1914, 1999.
    • (1999) TheEMBOJournal , vol.18 , Issue.7 , pp. 1905-1914
    • Ema, M.1    Hirota, K.2    Mimura, J.3
  • 55
    • 0033600744 scopus 로고    scopus 로고
    • Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-B
    • K. Hirota, M. Murata, Y. Sachi et al., " Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-B, " Journal of Biological Chemistry, vol. 274, no. 39, pp. 27891-27897, 1999.
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.39 , pp. 27891-27897
    • Hirota, K.1    Murata, M.2    Sachi, Y.3
  • 56
    • 0034681378 scopus 로고    scopus 로고
    • A redox mechanism controls differential DNA binding activities of hypoxia-inducible factor (HIF) 1 and the HIF-like factor, "
    • Lando D.,Pongratz I.,Poellinger L.,Whitelaw M.L. A redox mechanism controls differential DNA binding activities of hypoxia-inducible factor (HIF) 1 and the HIF-like factor, "The Journal of Biological Chemistry 2000 275 7 4618-4627.
    • (2000) The Journal of Biological Chemistry , vol.275 , Issue.7 , pp. 4618-4627
    • Lando, D.1    Pongratz, I.2    Poellinger, L.3    Whitelaw, M.L.4
  • 57
    • 0034160089 scopus 로고    scopus 로고
    • An nenvironment to nucleus signaling system operates in B lymphocytes: Redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation
    • G. Tell, A. Zecca, L. Pellizzari et al., " An " environment to nucleus" signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation," Nucleic Acids Research, vol. 28, no. 5, pp. 1099-1105, 2000.
    • (2000) Nucleic Acids Research , vol.28 , Issue.5 , pp. 1099-1105
    • Tell, G.1    Zecca, A.2    Pellizzari, L.3
  • 58
    • 0033544915 scopus 로고    scopus 로고
    • Thioredoxin-dependent redox regulation of p53-mediated p21 activation
    • M.Ueno,H.Masutani, R. J. Arai et al., " Thioredoxin-dependent redox regulation of p53-mediated p21 activation," Journal of Biological Chemistry, vol. 274, no. 50, pp. 35809-35815, 1999.
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.50 , pp. 35809-35815
    • Ueno, M.1    Masutani, H.2    Arai, R.J.3
  • 59
    • 0030903691 scopus 로고    scopus 로고
    • Redox regulation of the DNA binding activity in transcription factor PEBP2 the roles of two conserved cysteine residues: The roles of two conserved cysteine residues
    • Y. Akamatsu, T. Ohno, K. Hirota, H. Kagoshima, J. Yodoi, and K. Shigesada, " Redox regulation of the DNA binding activity in transcription factor PEBP2 the roles of two conserved cysteine residues: the roles of two conserved cysteine residues, " The Journal of Biological Chemistry, vol. 272, no.23, pp. 14497-14500, 1997.
    • (1997) The Journal of Biological Chemistry , vol.272 , Issue.23 , pp. 14497-14500
    • Akamatsu, Y.1    Ohno, T.2    Hirota, K.3    Kagoshima, H.4    Yodoi, J.5    Shigesada, K.6
  • 60
    • 0027456704 scopus 로고
    • Characterization of the DNA-binding properties of the e arly growth response-1 (Egr-1) transcription factor: Evidence for modulation by a redox mechanism
    • R. P. Huang and E. D. Adamson, "Characterization of the DNA-binding properties of the e arly growth response-1 (Egr-1) transcription factor: evidence for modulation by a redox mechanism," DNA and Cell Biology, vol. 12, no. 3, pp. 265-273, 1993.
    • (1993) DNA and Cell Biology , vol.12 , Issue.3 , pp. 265-273
    • Huang, R.P.1    Adamson, E.D.2
  • 61
    • 0026714672 scopus 로고
    • Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme
    • S. Xanthoudakis, G. Miao, F.Wang, Y. C. Pan, and T. Curran, " Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme," Journal of Cellular Biochemistry, vol. 11, no. 9, pp. 3323-3335, 1993.
    • (1993) Journal of Cellular Biochemistry , vol.11 , Issue.9 , pp. 3323-3335
    • Xanthoudakis, S.1    Miao, G.2    Wang, F.3    Pan, Y.C.4    Curran, T.5
  • 62
    • 0025077481 scopus 로고
    • Redox regulation of Fos and Jun DNA-binding activity in vitro
    • C. Abate , L. Patel, F. J. Rauscher III, and T. Curran, " Redox regulation of Fos and Jun DNA-binding activity in vitro," Science, vol. 249, no. 4973, pp. 1157-1161, 1990.
    • (1990) Science , vol.249 , Issue.4973 , pp. 1157-1161
    • Abate, C.1    Patel, L.2    Rauscher, F.J.3    Curran, T.4
  • 64
    • 0027361046 scopus 로고
    • Redox modulation of p53 conformation and sequence-specific DNA binding in vitro
    • P. Hainaut and J. Milner, "Redox modulation of p53 conformation and sequence-specific DNA binding in vitro, " Cancer Research, vol. 53, no. 18, pp. 4469-4473, 1993.
    • (1993) Cancer Research , vol.53 , Issue.18 , pp. 4469-4473
    • Hainaut, P.1    Milner, J.2
  • 65
    • 77951804865 scopus 로고    scopus 로고
    • Redox regulation of DNA repair: Implications for human health and cancer therapeutic development
    • M.-H. Luo, H.-Z. He, M. R. Kelley, and M. M. Georgiadis, " Redox regulation of DNA repair: implications for human health and cancer therapeutic development," Antioxidants & Redox Signaling, vol. 12, no. 11, pp. 1247-1269, 2010.
    • (2010) Antioxidants & Redox Signaling , vol.12 , Issue.11 , pp. 1247-1269
    • Luo, M.-H.1    He, H.-Z.2    Kelley, M.R.3    Georgiadis, M.M.4
  • 66
    • 11244344381 scopus 로고    scopus 로고
    • P53: Traffic cop at the crossroads of DNA repair and recombination
    • S. Sengupta and C. C. Harris, "p53: traffic cop at the crossroads of DNA repair and recombination, " Nature Reviews Molecular Cell Biology, vol. 6, no. 1, pp. 44-55, 2005.
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.1 , pp. 44-55
    • Sengupta, S.1    Harris, C.C.2
  • 67
    • 0036772333 scopus 로고    scopus 로고
    • Coordination of altered DNA repair and damage pathways in arsenite-exposed keratinocytes
    • 66] H. K. Hamadeh, K. J. Trouba, R. P. Amin, C. A. Afshari, and D. Germolec, " Coordination of altered DNA repair and damage pathways in arsenite-exposed keratinocytes," Toxicological Sciences, vol. 69, no. 2, pp. 306-316, 2002.
    • (2002) Toxicological Sciences , vol.69 , Issue.2 , pp. 306-316
    • Hamadeh, H.K.1    Trouba, K.J.2    Amin, R.P.3    Afshari, C.A.4    Germolec, D.5
  • 68
    • 0037838835 scopus 로고    scopus 로고
    • Genomic and proteomic profiling of responses to toxic metals in human lung cells
    • A. S. Andrew, A. J.Warren, A. Barchowsky et al., " Genomic and proteomic profiling of responses to toxic metals in human lung cells," Environmental Health Perspectives, vol. 111, no. 6, pp. 825-838, 2003.
    • (2003) Environmental Health Perspectives , vol.111 , Issue.6 , pp. 825-838
    • Andrew, A.S.1    Warren, A.J.2    Barchowsky, A.3
  • 69
    • 0037036585 scopus 로고    scopus 로고
    • Effect of arsenic on transcription factor AP-1 and NF-B DNA binding activity and related gene expression
    • Y. Hu, X. M. Jin, and E. T. Snow, " Effect of arsenic on transcription factor AP-1 and NF-B DNA binding activity and related gene expression," Toxicology Letters, vol. 133, no. 1, pp. 33-45, 2002.
    • (2002) Toxicology Letters , vol.133 , Issue.1 , pp. 33-45
    • Hu, Y.1    Jin, X.M.2    Snow, E.T.3
  • 70
    • 41949110712 scopus 로고    scopus 로고
    • Modulation of DNA polymerase beta-dependent base excision repair in cultured human cells after low dose exposure to arsenite
    • P. Sykora and E. T. Snow, " Modulation of DNA polymerase beta-dependent base excision repair in cultured human cells after low dose exposure to arsenite, " Toxicology and Applied Pharmacology, vol. 228, no. 3, pp. 385-394, 2008.
    • (2008) Toxicology and Applied Pharmacology , vol.228 , Issue.3 , pp. 385-394
    • Sykora, P.1    Snow, E.T.2
  • 71
    • 37549004372 scopus 로고    scopus 로고
    • ATF4-dependent oxidative induction of the DNA repair enzyme Ape1 co unteracts arsenite cytotoxicity and suppresses arsenite-mediated mutagenesis
    • H. Fung, P. Liu, and B. Demple, "ATF4-dependent oxidative induction of the DNA repair enzyme Ape1 co unteracts arsenite cytotoxicity and suppresses arsenite-mediated mutagenesis," Molecular and Cellular Biology, vol. 27, no. 24, pp. 8834-8847, 2007.
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.24 , pp. 8834-8847
    • Fung, H.1    Liu, P.2    Demple, B.3
  • 72
    • 80053132214 scopus 로고    scopus 로고
    • Polymorphic trial in oxidative damage of arsenic exposed Vietnamese
    • J. Fujihara, M. Soejima, T. Yasuda et al., " Polymorphic trial in oxidative damage of arsenic exposed Vietnamese," Toxicology and Applied Pharmacology, vol. 256, no. 2, pp. 174-178, 2011.
    • (2011) Toxicology and Applied Pharmacology , vol.256 , Issue.2 , pp. 174-178
    • Fujihara, J.1    Soejima, M.2    Yasuda, T.3
  • 73
    • 34547824703 scopus 로고    scopus 로고
    • Susceptibility to arsenicinduced skin lesions from polymorphisms in base excision repair genes
    • C.V. Breton,W. Zhou, M. L.Kile et al., " Susceptibility to arsenicinduced skin lesions from polymorphisms in base excision repair genes, " Carcinogenesis, vol. 28, no. 7, pp. 1520-1525, 2007.
    • (2007) Carcinogenesis , vol.28 , Issue.7 , pp. 1520-1525
    • Breton, C.V.1    Zhou, W.2    Kile, M.L.3
  • 74
    • 2642554095 scopus 로고    scopus 로고
    • Inhibition of Ape1 nuclease activity by lead, iron, and cadmium
    • D. R. McNeill, A. Narayana, H. Wong, and D. M. Wilson III, " Inhibition of Ape1 nuclease activity by lead, iron, and cadmium," Environmental Health Perspectives, vol. 112, no. 7, pp. 799-804, 2004.
    • (2004) Environmental Health Perspectives , vol.112 , Issue.7 , pp. 799-804
    • McNeill, D.R.1    Narayana, A.2    Wong, H.3    Wilson, D.M.4
  • 76
    • 84880340355 scopus 로고    scopus 로고
    • Effect of long-term human exposure to environmental heavy metals on the expression of detoxification and DNA repair genes
    • S. A. Al Bakheet, I. M. Attafi, Z. H. Maayah, A. R. Abd-Allah, Y. A. Asiri, and H. M. Korashy, " Effect of long-term human exposure to environmental heavy metals on the expression of detoxification and DNA repair genes, " Environmental Pollution, vol. 181, pp. 226-232, 2013
    • (2013) Environmental Pollution , vol.181 , Issue.1 , pp. 226-232
    • Al Bakheet, S.A.1    Attafi, I.M.2    Maayah, Z.H.3    Abd-Allah, A.R.4    Asiri, Y.A.5    Korashy, H.M.6
  • 77
    • 75749105357 scopus 로고    scopus 로고
    • Inactivation by oxidation and recruitment into stress granules of hOGG1 but not APE1 in human cells exposed to sub-lethal concentrations of cadmium
    • A. Bravard,A. Campalans,M. Vacher,et al. Inactivation by oxidation and recruitment into stress granules of hOGG1 but not APE1 in human cells exposed to sub-lethal concentrations of cadmium, " Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis 685, 1?2 ,61-69, 2010
    • (2010) Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis , vol.685 , Issue.2 , pp. 61-69
    • Bravard, A.1    Campalans, A.2    Vacher, M.3
  • 78
    • 0033900168 scopus 로고    scopus 로고
    • IncreasedAP-1DNA-binding activity and nuclear REF-1 accumulation in lead-exposed primary cultures of astrocytes
    • M. Scortegagna and I.Hanbauer, " IncreasedAP-1DNA-binding activity and nuclear REF-1 accumulation in lead-exposed primary cultures of astrocytes," Neurochemical Research, vol. 25, no. 6, pp. 861-866, 2000.
    • (2000) Neurochemical Research , vol.25 , Issue.6 , pp. 861-866
    • Scortegagna, M.1    Hanbauer, I.2
  • 79
    • 84860140700 scopus 로고    scopus 로고
    • Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair
    • J. Ga rciá-Lestón, J. Roma-Torres, M. Vilares et al., " Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair, " Environment International, vol. 43, no. 1, pp. 29-36, 2012.
    • (2012) Environment International , vol.43 , Issue.1 , pp. 29-36
    • Ga Rciá-Lestón, J.1    Roma-Torres, J.2    Vilares, M.3
  • 80
    • 80053442450 scopus 로고    scopus 로고
    • Cigarette smoke induces DNA damage and alters base-excision repair and tau levels in the brain of neonatal mice
    • S. la Maestra, G. E. Kisby, R. T. Micale et al., " Cigarette smoke induces DNA damage and alters base-excision repair and tau levels in the brain of neonatal mice," Toxicological Sciences, vol. 123, no. 2, pp. 471-479, 2011.
    • (2011) Toxicological Sciences , vol.123 , Issue.2 , pp. 471-479
    • La Maestra, S.1    Kisby, G.E.2    Micale, R.T.3
  • 81
    • 58349113424 scopus 로고    scopus 로고
    • A polymorphism in the APE1 gene promoter is associated with lung cancer risk
    • Y. Lo, Y. Jou, C. Hsiao et al., " A polymorphism in the APE1 gene promoter is associated with lung cancer risk," Cancer Epidemiology Biomarkers and Prevention, vol. 18, no. 1, pp. 223-229, 2009.
    • (2009) Cancer Epidemiology Biomarkers and Prevention , vol.18 , Issue.1 , pp. 223-229
    • Lo, Y.1    Jou, Y.2    Hsiao, C.3
  • 82
    • 4344602545 scopus 로고    scopus 로고
    • Gene-environment interactions between the smoking habit and polymorphisms in the DNA repair genes, APE1 Asp148Glu and XRCC1 Arg399Gln, in Japanese lung cancer risk,"
    • H. Ito, K. Matsuo, N. Hamajima et al., "Gene-environment interactions between the smoking habit and polymorphisms in the DNA repair genes, APE1 Asp148Glu and XRCC1 Arg399Gln, in Japanese lung cancer risk," Carcinogenesis vol. 25, no. 8, pp. 1395-1401, 2004.
    • (2004) Carcinogenesis , vol.25 , Issue.8 , pp. 1395-1401
    • Ito, H.1    Matsuo, K.2    Hamajima, N.3
  • 83
    • 67650915080 scopus 로고    scopus 로고
    • Apurinic/apyrimidinic endonuclease (APE1) gene polymorphisms and lung cancer risk in relation to tobacco smoking
    • B. Agaçhan, O. Küçükhüseyin, P. Aksoy et al., "Apurinic/apyrimidinic endonuclease (APE1) gene polymorphisms and lung cancer risk in relation to tobacco smoking, " Anticancer Research, vol. 29, no. 6, pp. 2417-2420, 2009.
    • (2009) Anticancer Research , vol.29 , Issue.6 , pp. 2417-2420
    • Agaçhan, B.1    Küçükhüseyin, O.2    Aksoy, P.3
  • 84
    • 79955946534 scopus 로고    scopus 로고
    • APEX1 Asp148glu gene polymorphism is a risk factor for lung cancer in relation to smoking in Japanese
    • K.Osawa,A.Miyaishi, K. Uchino et al., " APEX1 Asp148glu gene polymorphism is a risk factor for lung cancer in relation to smoking in Japanese," Asian Pacific Journal of Cancer Prevention, vol. 11, no. 5, pp. 1181-1186, 2010.
    • (2010) Asian Pacific Journal of Cancer Prevention , vol.11 , Issue.5 , pp. 1181-1186
    • Osawa, K.1    Miyaishi, A.2    Uchino, K.3
  • 85
    • 33846580207 scopus 로고    scopus 로고
    • High-order interactions among genetic variants in DNA base excision repair pathway genes and smoking in bladder cancer susceptibility
    • M. Huang, C. P. Dinney, X. Lin, J. Lin, H. B. Grossman, and X. Wu, " High-order interactions among genetic variants in DNA base excision repair pathway genes and smoking in bladder cancer susceptibility, " Cancer Epidemiology Biomarkers and Prevention, vol. 16, no. 1, pp. 84-91, 2007.
    • (2007) Cancer Epidemiology Biomarkers and Prevention , vol.16 , Issue.1 , pp. 84-91
    • Huang, M.1    Dinney, C.P.2    Lin, X.3    Lin, J.4    Grossman, H.B.5    Wu, X.6
  • 86
    • 0037430538 scopus 로고    scopus 로고
    • Polymorphisms in the DNA repair genes XPD, XRCC1, XRCC3, and APE/ref-1, and the risk of lung cancer among male smokers in Finland
    • R. R. Misra, D. Ratnasinghe, J. A. Tangrea et al., " Polymorphisms in the DNA repair genes XPD, XRCC1, XRCC3, and APE/ref-1, and the risk of lung cancer among male smokers in Finland, " Cancer Letters, vol. 191, no. 2, pp. 171-178, 2003.
    • (2003) Cancer Letters , vol.191 , Issue.2 , pp. 171-178
    • Misra, R.R.1    Ratnasinghe, D.2    Tangrea, J.A.3
  • 87
    • 33750302131 scopus 로고    scopus 로고
    • Polymorphisms in the DNA repair genes XRCC1, APEX1, XRCC3 and NBS1, and the risk for lung cancer in never-and ever-smokers
    • C. Ryk, R. Kumar, R. K. Thirumaran, and S. Hou, " Polymorphisms in the DNA repair genes XRCC1, APEX1, XRCC3 and NBS1, and the risk for lung cancer in never-and ever-smokers," Lung Cancer, vol. 54, no. 3, pp. 285-292, 2006.
    • (2006) Lung Cancer , vol.54 , Issue.3 , pp. 285-292
    • Ryk, C.1    Kumar, R.2    Thirumaran, R.K.3    Hou, S.4
  • 88
    • 33646402349 scopus 로고    scopus 로고
    • APE1 genotype and risk of bladder cancer: Evidence for effect modification by smoking
    • P. D. Terry, D. M. Umbach , and J. A. Taylor, " APE1 genotype and risk of bladder cancer: evidence for effect modification by smoking," International Journal of Cancer, vol. 118, no. 12, pp. 3170-3173, 2006.
    • (2006) International Journal of Cancer , vol.118 , Issue.12 , pp. 3170-3173
    • Terry, P.D.1    Umbach, D.M.2    Taylor, J.A.3
  • 89
    • 9244235164 scopus 로고    scopus 로고
    • Alterations of gene expression in skin and lung of mice exposed to light and cigarette smoke
    • A. Izzotti, C. Cartiglia, M. Longobardi et al., " Alterations of gene expression in skin and lung of mice exposed to light and cigarette smoke," The FASEB Journal, vol. 18, no. 13, pp. 1559-1561, 2004.
    • (2004) The FASEB Journal , vol.18 , Issue.13 , pp. 1559-1561
    • Izzotti, A.1    Cartiglia, C.2    Longobardi, M.3
  • 90
    • 0346243565 scopus 로고    scopus 로고
    • Functional characterization of polymorphisms in DNA repair genes using cytogenetic challenge assays
    • W. W. Au, S. A. Salama, and C. H. Sierra-Torres, " Functional characterization of polymorphisms in DNA repair genes using cytogenetic challenge assays," Environmental Health Perspectives, vol. 111, no. 15, pp. 1843-1850, 2003.
    • (2003) Environmental Health Perspectives , vol.111 , Issue.15 , pp. 1843-1850
    • Au, W.W.1    Salama, S.A.2    Sierra-Torres, C.H.3
  • 91
    • 33846782890 scopus 로고    scopus 로고
    • UVA irradiation induces relocalisation of the DNA repair protein hOGG1 to nuclear speckles
    • A. Campalans, R. Amouroux, A. Bravard, B. Epe, and J. P. Radicella, " UVA irradiation induces relocalisation of the DNA repair protein hOGG1 to nuclear speckles," Journal of Cell Science, vol. 120, no. 1, pp. 23-32, 2007.
    • (2007) Journal of Cell Science , vol.120 , Issue.1 , pp. 23-32
    • Campalans, A.1    Amouroux, R.2    Bravard, A.3    Epe, B.4    Radicella, J.P.5
  • 92
    • 0034981858 scopus 로고    scopus 로고
    • Amino acid substitution variants of APE1 and XRCC1 genes associated with ionizing radiation sensitivity
    • J. J. Hu, T. R. Smith, M. S. Miller, H. W. Mohrenweiser, A. Golden, and L. D. Case, " Amino acid substitution variants of APE1 and XRCC1 genes associated with ionizing radiation sensitivity, " Carcinogenesis, vol. 22, no. 6, pp. 917-922, 2001.
    • (2001) Carcinogenesis , vol.22 , Issue.6 , pp. 917-922
    • Hu, J.J.1    Smith, T.R.2    Miller, M.S.3    Mohrenweiser, H.W.4    Golden, A.5    Case, L.D.6
  • 94
    • 66049090395 scopus 로고    scopus 로고
    • Genetic polymorphisms in XRCC1,OGG1, APE1 and XRCC3 DNA repair genes, ionizing radiation exposure and chromosomal DNA damage in interventional cardiologists, "
    • M. G. Andreassi, I. Foffa, S. Ma nfredi, N. Botto, A. Cioppa, and E. Picano, " Genetic polymorphisms in XRCC1,OGG1, APE1 and XRCC3 DNA repair genes, ionizing radiation exposure and chromosomal DNA damage in interventional cardiologists, " Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis, vol. 666, no. 1- 2, pp. 57-63, 2009.
    • (2009) Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis , vol.666 , Issue.1-2 , pp. 57-63
    • Andreassi, M.G.1    Foffa, I.2    Ma Nfredi, S.3    Botto, N.4    Cioppa, A.5    Picano, E.6
  • 95
    • 84878420112 scopus 로고    scopus 로고
    • Human apurinic/apyrimidinic endonuclease siRNA inhibits the angiogenesis induced by XRay irradiation in lung cancer cells
    • X. Gu, Y. Cun, M. Li et al., " Human apurinic/apyrimidinic endonuclease siRNA inhibits the angiogenesis induced by XRay irradiation in lung cancer cells, " International Journal of Medical Sciences, vol. 10, no. 7, pp. 870-882, 2013.
    • (2013) International Journal of Medical Sciences , vol.10 , Issue.7 , pp. 870-882
    • Gu, X.1    Cun, Y.2    Li, M.3
  • 96
    • 81155152597 scopus 로고    scopus 로고
    • Nm23-H1 protein binds to APE1 at AP sites and stimulates AP endonuclease activity following ionizing radiation of the human lung cancer A549 cells
    • Z. Zhang, X. Yang, D. Wang et al., " Nm23-H1 protein binds to APE1 at AP sites and stimulates AP endonuclease activity following ionizing radiation of the human lung cancer A549 cells, " Cell Biochemistry and Biophysics, vol. 61, no. 3, pp. 561-572, 2011.
    • (2011) Cell Biochemistry and Biophysics , vol.61 , Issue.3 , pp. 561-572
    • Zhang, Z.1    Yang, X.2    Wang, D.3
  • 98
    • 43049167396 scopus 로고    scopus 로고
    • Characterization of abasic endonuclease activity of human Ape1 on alternative substrates, as well as effects of ATP and sequence context on AP site incision
    • B. R. Berquist,D. R. McNeill,D. M. Wilson III Characterization of abasic endonuclease activity of human Ape1 on alternative substrates, as well as effects of ATP and sequence context on AP site incision, " Journal of Molecular Biology ,379 ,1, 17-27, 2008.
    • (2008) Journal of Molecular Biology , vol.379 , Issue.1 , pp. 17-27
    • Berquist, B.R.1    McNeill, D.R.2    Wilson, D.M.3
  • 99
    • 77953484497 scopus 로고    scopus 로고
    • DNA repair in mammalian mitochondria: Much more th an we thought
    • P. F. Liu and B. Demple, "DNA repair in mammalian mitochondria: much more th an we thought?" Environmental and Molecular Mutagenesis, vol. 51, no. 5, pp. 417-426, 2010.
    • (2010) Environmental and Molecular Mutagenesis , vol.51 , Issue.5 , pp. 417-426
    • Liu, P.F.1    Demple, B.2
  • 100
    • 67651149733 scopus 로고    scopus 로고
    • Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA
    • T. Barnes, W. Kim, A. K. Mantha et al., " Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA, " Nucleic Acids Research, vol. 37, no. 12, pp. 3946-3958, 2009.
    • (2009) Nucleic Acids Research , vol.37 , Issue.12 , pp. 3946-3958
    • Barnes, T.1    Kim, W.2    Mantha, A.K.3
  • 101
    • 36549036731 scopus 로고    scopus 로고
    • APE1-And APE2-dependent DNA breaks in immunoglobulin class switch recombination
    • J. E. J. Guikema, E. K. Linehan, D. Tsuchimoto et al., " APE1-And APE2-dependent DNA breaks in immunoglobulin class switch recombination," Journal of Experimental Medicine, vol. 204, no. 12, pp. 3017-3026, 2007.
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.12 , pp. 3017-3026
    • Guikema, J.E.J.1    Linehan, E.K.2    Tsuchimoto, D.3
  • 102
    • 84875265549 scopus 로고    scopus 로고
    • Apurinic/apy rimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination
    • S. Masani, L. Han, and K. Yu, "Apurinic/apy rimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination," Molecular and Cellular Biology, vol. 33, no. 7, pp. 1468-1473, 2013.
    • (2013) Molecular and Cellular Biology , vol.33 , Issue.7 , pp. 1468-1473
    • Masani, S.1    Han, L.2    Yu, K.3
  • 103
    • 0034027636 scopus 로고    scopus 로고
    • Evidence that the bifunctional redox factor/AP endonuclease Ref-1 is an anti-apoptotic protein associated with differentiation in the developing retina
    • L. B. Chiarini, F. G. Freitas, H. Petrs-Silva, and R. Linden, " Evidence that the bifunctional redox factor/AP endonuclease Ref-1 is an anti-apoptotic protein associated with differentiation in the developing retina, " Cell Death and Differentiation, vol. 7, no. 3, pp. 272-281, 2000.
    • (2000) Cell Death and Differentiation , vol.7 , Issue.3 , pp. 272-281
    • Chiarini, L.B.1    Freitas, F.G.2    Petrs-Silva, H.3    Linden, R.4
  • 104
    • 77955095659 scopus 로고    scopus 로고
    • Human AP endonuclease 1 (APE1): From mechanistic insights to druggable target in cancer
    • R. Abbotts and S. Madhusudan, "Human AP endonuclease 1 (APE1): from mechanistic insights to druggable target in cancer, " Cancer Treatment Reviews, vol. 36, no. 5, pp. 425-435, 2010.
    • (2010) Cancer Treatment Reviews , vol.36 , Issue.5 , pp. 425-435
    • Abbotts, R.1    Madhusudan, S.2
  • 105
    • 37549033163 scopus 로고    scopus 로고
    • Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth
    • M. L. Fishel, Y.He, A. M. Reed et al., " Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth, " DNA Repair, vol. 7, no. 2, pp. 177-186, 2008.
    • (2008) DNA Repair , vol.7 , Issue.2 , pp. 177-186
    • Fishel, M.L.1    He, Y.2    Reed, A.M.3
  • 106
    • 77958001097 scopus 로고    scopus 로고
    • Reduced expression of DNA repair and redox signaling protein APE1/Ref-1 impairs human pancreatic cancer cell survival, proliferation, and cell cycle progression
    • Y. L. Jiang, S. Y. Zhou, G. E. Sandusky, M. R. Kelley, and M. L. Fishel, " Reduced expression of DNA repair and redox signaling protein APE1/Ref-1 impairs human pancreatic cancer cell survival, proliferation, and cell cycle progression, " Cancer Investigation, vol. 28, no. 9, pp. 885-895, 2010.
    • (2010) Cancer Investigation , vol.28 , Issue.9 , pp. 885-895
    • Jiang, Y.L.1    Zhou, S.Y.2    Sandusky, G.E.3    Kelley, M.R.4    Fishel, M.L.5
  • 107
    • 0033961301 scopus 로고    scopus 로고
    • Alterations in the expression of the DNA repair/redox enzyme APE/ref-1 in epithelial ovarian cancers
    • D. H. Moore, H. Mic hael, R. Tritt, S. H. Parsons, and M. R. Kelley, " Alterations in the expression of the DNA repair/redox enzyme APE/ref-1 in epithelial ovarian cancers," Clinical Cancer Research, vol. 6, no. 2, pp. 602-609, 2000.
    • (2000) Clinical Cancer Research , vol.6 , Issue.2 , pp. 602-609
    • Moore, D.H.1    Mic Hael, H.2    Tritt, R.3    Parsons, S.H.4    Kelley, M.R.5
  • 108
  • 109
    • 4444327784 scopus 로고    scopus 로고
    • Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: Enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition, "
    • D.Wang, M. Luo, and M. R. Kelley, " Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition, " Molecular CancerTherapeutics, vol. 3, no. 6, pp. 679-686, 2004.
    • (2004) Molecular CancerTherapeutics , vol.3 , Issue.6 , pp. 679-686
    • Wang, D.1    Luo, M.2    Kelley, M.R.3
  • 110
    • 7844241550 scopus 로고    scopus 로고
    • Levels of TheDNA Repair Enzyme Human Apurinic/apyrimidinic Endonuclease (APE1, APEX, Ref-1) Are Associated with the Intrinsic Radiosensitivity of Cervical Cancers
    • C. J. Herring, C. M. L. West, D. P. Wilks et al., "Levels of theDNA repair enzyme human apurinic/apyrimidinic endonuclease (APE1, APEX, Ref-1) are associated with the intrinsic radiosensitivity of cervical cancers," vol. 78, no. 9, pp. 1128-1133, 1998.
    • (1998) Radiosensitivity of Cervical Cancers , vol.78 , pp. 1128-1133
    • Herring, C.J.1    West, C.M.L.2    Wilks, D.P.3
  • 111
    • 51449094587 scopus 로고    scopus 로고
    • Chimeric adenoviral vector Ad5/F35-mediated APE1 siRNA enhances sensitivity of human colorectal cancer cells to radiotherapy in vitro and in vivo
    • D.-B. Xiang, Z.-T. Chen, D. Wang et al., " Chimeric adenoviral vector Ad5/F35-mediated APE1 siRNA enhances sensitivity of human colorectal cancer cells to radiotherapy in vitro and in vivo, " Cancer Gene Therapy, vol. 15, no. 10, pp. 625-635, 2008.
    • (2008) Cancer Gene Therapy , vol.15 , Issue.10 , pp. 625-635
    • Xiang, D.-B.1    Chen, Z.-T.2    Wang, D.3
  • 112
    • 84874718458 scopus 로고    scopus 로고
    • Downregu lation of apurinic/apyrimidinic endonuclease 1/redox factor-1 enhances the sensitivity of human pancreatic cancer cells to radiotherapy in vitro
    • S. Chen, G. Xiong, S. Wu, and J. Mo, "Downregu lation of apurinic/apyrimidinic endonuclease 1/redox factor-1 enhances the sensitivity of human pancreatic cancer cells to radiotherapy in vitro," Cancer Biotherapy and Radiopharmaceuticals, vol. 28, no. 2, pp. 169-176, 2013.
    • (2013) Cancer Biotherapy and Radiopharmaceuticals , vol.28 , Issue.2 , pp. 169-176
    • Chen, S.1    Xiong, G.2    Wu, S.3    Mo, J.4
  • 113
    • 0035266131 scopus 로고    scopus 로고
    • Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation
    • K. A. Robertson, H. A. Bullock, Y. Xu et al., " Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation, " Cancer Research, vol. 61, no. 5, pp. 2220-2225, 2001.
    • (2001) Cancer Research , vol.61 , Issue.5 , pp. 2220-2225
    • Robertson, K.A.1    Bullock, H.A.2    Xu, Y.3
  • 114
    • 2642527702 scopus 로고    scopus 로고
    • Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function
    • T. Xi, I. M. Jones, and H. W. Mohrenweiser, " Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function, " Genomics, vol. 83, no. 6, pp. 970-979, 2004.
    • (2004) Genomics , vol.83 , Issue.6 , pp. 970-979
    • Xi, T.1    Jones, I.M.2    Mohrenweiser, H.W.3
  • 115
    • 0034668113 scopus 로고    scopus 로고
    • Functional characterization of Ape1 variants identified in the human population
    • M. Z.Hadi,M.A.Coleman,K. Fidelis, H.W.Mohrenweiser, and D. M.Wilson III, " Functional characterization of Ape1 variants identified in the human population," Nucleic Acids Research, vol. 28, no. 20, pp. 3871-3879, 2000.
    • (2000) Nucleic Acids Research , vol.28 , Issue.20 , pp. 3871-3879
    • Hadi, M.Z.1    Coleman, M.A.2    Fidelis, K.3    Mohrenweiser, H.W.4    Wilson, D.M.5
  • 116
    • 27744531188 scopus 로고    scopus 로고
    • Genetic polymorphisms in the base excision repair pathway and cancer risk: A huge review
    • R. J. Hung, J. Hall, P. Brennan, and P. Boffetta, " Genetic polymorphisms in the base excision repair pathway and cancer risk: a huge review," The American Journal of Epidemiology, vol. 162, no. 10, pp. 925-942, 2005.
    • (2005) The American Journal of Epidemiology , vol.162 , Issue.10 , pp. 925-942
    • Hung, R.J.1    Hall, J.2    Brennan, P.3    Boffetta, P.4
  • 117
    • 77953772492 scopus 로고    scopus 로고
    • Possible associations of APE1 polymorphism with susceptibility and HOGG1 polymorphism with prognosis in gastric cancer
    • E. Canbay, B. Agachan, M. Gu lluoglu et al., " Possible associations of APE1 polymorphism with susceptibility and HOGG1 polymorphism with prognosis in gastric cancer," Anticancer Research, vol. 30, no. 4, pp. 1359-1364, 2010.
    • (2010) Anticancer Research , vol.30 , Issue.4 , pp. 1359-1364
    • Canbay, E.1    Agachan, B.2    Gu Lluoglu, M.3
  • 118
    • 79958864965 scopus 로고    scopus 로고
    • Association of APE1 and hOGG1 polymorphisms with colorectal cancer risk in aTurkish population
    • rffrt [117] E. Canbay, B. Cakmakoglu, U. Zeybek et al., " Association of APE1 and hOGG1 polymorphisms with colorectal cancer risk in aTurkish population," CurrentMedical Research andOpinion, vol. 27, no. 7, pp. 1295-1302, 2011.
    • (2011) CurrentMedical Research AndOpinion , vol.27 , Issue.7 , pp. 1295-1302
    • Canbay, E.1    Cakmakoglu, B.2    Zeybek, U.3
  • 119
    • 29144471254 scopus 로고    scopus 로고
    • Association between polymorphisms in theDNA repair genes XRCC1 and APE1, and the risk of prostate cancer in white and black Americans
    • L. Chen,C. B. Ambrosone,J. Lee,T. A. Sellers,J. Pow-Sang,J. Y. Park Association between polymorphisms in theDNA repair genes XRCC1 and APE1, and the risk of prostate cancer in white and black Americans Journal of Urology ,175 , 1 ,108-112 ,2006
    • (2006) Journal of Urology , vol.175 , Issue.1 , pp. 108-112
    • Chen, L.1    Ambrosone, C.B.2    Lee, J.3    Sellers, T.A.4    Pow-Sang, J.5    Park, J.Y.6
  • 120
    • 33747877809 scopus 로고    scopus 로고
    • Genetic variants of the ADPRT, XRCC1 and APE1 genes and risk of cutaneous melanoma
    • C. Li,Z. Liu,L. Wang,et al. Genetic variants of the ADPRT, XRCC1 and APE1 genes and risk of cutaneous melanoma," Carcinogenesis 27 9 1894-1901 2006.
    • (2006) BCarcinogenesis , vol.27 , Issue.9 , pp. 1894-1901
    • Li, C.1    Liu, Z.2    Wang, L.3
  • 121
    • 84873956952 scopus 로고    scopus 로고
    • Polymorphisms in genes of APE1, PARP1, and XRCC1: Risk and prognosis of colorectal cancer in a Northeast Chinese population
    • 505
    • Y. Li, S. Li, Z. Wu et al., " Polymorphisms in genes of APE1, PARP1, and XRCC1: risk and prognosis of colorectal cancer in a Northeast Chinese population, " Medical Oncology, vol. 30, no. 2, article no. 505, 2013.
    • Medical Oncology , vol.30 , Issue.2 , pp. 2013
    • Li, Y.1    Li, S.2    Wu, Z.3
  • 122
    • 84884815776 scopus 로고    scopus 로고
    • A genetic variant in the promoter of APE1 gene (?656 T > G) is associated with breast cancer risk and progression in a Chinese population
    • H. F. Kang, Z. J. Dai, X. B. Ma et al., " A genetic variant in the promoter of APE1 gene (?656 T > G) is associated with breast cancer risk and progression in a Chinese population, " Gene, vol. 531, no. 1, pp. 97-100, 2013.
    • (2013) Gene , vol.531 , Issue.1 , pp. 97-100
    • Kang, H.F.1    Dai, Z.J.2    Ma, X.B.3
  • 123
    • 84884603647 scopus 로고    scopus 로고
    • Genetic variant in APE1 gene promoter contributes to cervical cancer risk
    • M.Wang, H. Chu, S.Wang et al., " Genetic variant in APE1 gene promoter contributes to cervical cancer risk," American Journal of Obstetrics and Gynecology, vol. 209, no. 4, pp. 360.e1-360.e7, 2013.
    • (2013) American Journal of Obstetrics and Gynecology , vol.209 , Issue.4 , pp. 360e1-360e7
    • Wang, M.1    Chu, H.2    Wang, S.3
  • 124
    • 77953926931 scopus 로고    scopus 로고
    • Genetic variants of XRCC1, APE1, and ADPRT genes and risk of bladder cancer
    • M. L.Wang, C.Qin, J. A. Zhu et al., " Genetic variants of XRCC1, APE1, and ADPRT genes and risk of bladder cancer," DNA and Cell Biology, vol. 29, no. 6, pp. 303-311, 2010.
    • (2010) DNA and Cell Biology , vol.29 , Issue.6 , pp. 303-311
    • Wang, M.L.1    Qin, C.2    Zhu, J.A.3
  • 125
    • 70349655091 scopus 로고    scopus 로고
    • Functional characterization of a promoter polymorphism in APE1/Ref-1 that contributes to reduced lung cancer susceptibility
    • J. Lu, S. Y. Zhang, D. Chen et al., " Functional characterization of a promoter polymorphism in APE1/Ref-1 that contributes to reduced lung cancer susceptibility, " The FASEB Journal, vol. 23, no. 10, pp. 3459-3469, 2009.
    • (2009) The FASEB Journal , vol.23 , Issue.10 , pp. 3459-3469
    • Lu, J.1    Zhang, S.Y.2    Chen, D.3
  • 126
    • 79959715401 scopus 로고    scopus 로고
    • Genetic polymorphism of DNA base-excision repair genes (APE1, OGG1 and XRCC1) and their correlation with risk of lung cancer in a Chinese population
    • Z. Li,W. Guan, M . Li et al., " Genetic polymorphism of DNA base-excision repair genes (APE1, OGG1 and XRCC1) and their correlation with risk of lung cancer in a Chinese population," Archives of Medical Research, vol. 42, no. 3, pp. 226-234, 2011.
    • (2011) Archives of Medical Research , vol.42 , Issue.3 , pp. 226-234
    • Li, W.1    Guan, Z.2    Li, M.3
  • 127
    • 80052447445 scopus 로고    scopus 로고
    • APE1 Asp148Glu gene polymorphism and lung cancer risk: A meta-analysis
    • Y. Ji, P. Zhan, J.Wang, L. Qiu, and L. Yu, " APE1 Asp148Glu gene polymorphism and lung cancer risk: a meta-analysis," Molecular Biology Reports, vol. 38, no. 7, pp. 4537-4543, 2011.
    • (2011) Molecular Biology Reports , vol.38 , Issue.7 , pp. 4537-4543
    • Ji, Y.1    Zhan, P.2    Wang, J.3    Qiu, L.4    Yu, L.5
  • 128
    • 80052473784 scopus 로고    scopus 로고
    • Genetic polymorphisms in ATM, ERCC1, APE1 and iASPP genes and lung cancer risk in a population of southeast China
    • Q. Deng, L. Sheng, D. Su et al., " Genetic polymorphisms in ATM, ERCC1, APE1 and iASPP genes and lung cancer risk in a population of southeast China," Medical Oncology, vol. 28, no. 3, pp. 667-672, 2011.
    • (2011) Medical Oncology , vol.28 , Issue.3 , pp. 667-672
    • Deng, Q.1    Sheng, L.2    Su, D.3
  • 129
    • 34247148449 scopus 로고    scopus 로고
    • Base excision repair and the central nervous system, "
    • D. M. Wilson III and D. R. McNeill, "Base excision repair and the central nervous system, " Neuroscience, vol. 145, no. 4, pp . 1187-1200, 2007.
    • (2007) Neuroscience , vol.145 , Issue.4 , pp. 1187-1200
  • 130
    • 12344291209 scopus 로고    scopus 로고
    • The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress
    • M. R. Vasko, C. Guo, and M. R. Kelley, " The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress," DNA Repair, vol. 4, no. 3, pp. 367-379, 2005.
    • (2005) DNA Repair , vol.4 , Issue.3 , pp. 367-379
    • Vasko, M.R.1    Guo, C.2    Kelley, M.R.3
  • 131
    • 0032563635 scopus 로고    scopus 로고
    • Immunohistochemical localization of redox factor-1 (Ref-1) in Alzheimer's hippocampus
    • Z. Tan, N. Sun, and S. S. Schreiber, "Immunohistochemical localization of redox factor-1 (Ref-1) in Alzheimer's hippocampus, " NeuroReport, vol. 9, no. 12, pp. 2749-2752, 1998.
    • (1998) NeuroReport , vol.9 , Issue.12 , pp. 2749-2752
    • Tan, Z.1    Sun, N.2    Schreiber, S.S.3
  • 132
    • 70350302327 scopus 로고    scopus 로고
    • APE1/Ref-1 in Alzheimer's disease: An immunohistochemical study
    • G.Marcon, G. Tell, L. Perrone et al., " APE1/Ref-1 in Alzheimer's disease: An immunohistochemical study," Neuroscience Letters, vol. 466, no. 3, pp. 124-127, 2009.
    • (2009) Neuroscience Letters , vol.466 , Issue.3 , pp. 124-127
    • Marcon, G.1    Tell, G.2    Perrone, L.3
  • 133
    • 0030916372 scopus 로고    scopus 로고
    • Evidence of reduced DNA repair in amyotrophic lateral sclerosis brain tissue
    • G. E. Kisby J. Milne and C. Sweatt Evidence of reduced DNA repair in amyotrophic lateral sclerosis brain tissue NeuroReport ,8 , 6, 1337-1340 , 1997
    • (1997) NeuroReport , vol.8 , Issue.6 , pp. 1337-1340
    • Kisby, G.E.1    Milne, J.2    Sweatt, C.3
  • 135
    • 0032567807 scopus 로고    scopus 로고
    • Mutant AP endonuclease in patients with amyotrophic lateral sclerosis
    • Z. L. Olkowski, " Mutant AP endonuclease in patients with amyotrophic lateral sclerosis," NeuroReport, vol. 9, no. 2, pp. 239-242, 1998.
    • (1998) NeuroReport , vol.9 , Issue.2 , pp. 239-242
    • Olkowski, Z.L.1
  • 136
    • 0036570012 scopus 로고    scopus 로고
    • Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells
    • V. A. Bohr, "Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells," Free Radical Biology and Medicine, vol. 32, no. 9, pp. 804-812, 2002.
    • (2002) Free Radical Biology and Medicine , vol.32 , Issue.9 , pp. 804-812
    • Bohr, V.A.1
  • 137
    • 0037341775 scopus 로고    scopus 로고
    • Agerelated base excision repair activity in mouse brain and liver nuclear extracts
    • G.W. Intano, E. J. Cho, C. A. McMahan, andC.A.Walter, " Agerelated base excision repair activity in mouse brain and liver nuclear extracts," Journals of Gerontology A, vol. 58, no. 3, pp. 205-211, 2003.
    • (2003) Journals of Gerontology A , vol.58 , Issue.3 , pp. 205-211
    • Intano, G.W.1    Cho, E.J.2    McMahan, C.A.3    Walter A, C.4
  • 138
    • 80053128348 scopus 로고    scopus 로고
    • Study of DNA damage via the comet assay and base excision repair activities in rat brain neurons and astrocytes during aging
    • U. Swain and K. S. Rao, "Study of DNA damage via the comet assay and base excision repair activities in rat brain neurons and astrocytes during aging," Mechanisms of Ageing and Development, vol. 132, no. 8- 9, pp. 374-381, 2011.
    • (2011) Mechanisms of Ageing and Development , vol.132 , Issue.8-9 , pp. 374-381
    • Swain, U.1    Rao, K.S.2
  • 139
    • 0035988381 scopus 로고    scopus 로고
    • Redox factor-1: An extra-nuclear role in the regulation of endothelial oxidative stress and apoptosis
    • P. Angkeow, S. S. Deshpande, B. Qi et al., " Redox factor-1: an extra-nuclear role in the regulation of endothelial oxidative stress and apoptosis," Cell Death and Differentiation, vol. 9, no. 7, pp. 717-725, 2002.
    • (2002) Cell Death and Differentiation , vol.9 , Issue.7 , pp. 717-725
    • Angkeow, P.1    Deshpande, S.S.2    Qi, B.3
  • 140
    • 77956958964 scopus 로고    scopus 로고
    • Expression changes in DNA repair enzymes and mitochondrial DNA damage in aging rat lens
    • Y. Zhang, L. Zhang, L. Zhang, J. Bai, H. Y. Ge, and P. Liu, " Expression changes in DNA repair enzymes and mitochondrial DNA damage in aging rat lens," Molecular Vision, vol. 16, pp. 1754-1763, 2010
    • Molecular Vision , vol.16 , Issue.2010 , pp. 1754-1763
    • Zhang, Y.1    Zhang, L.2    Zhang, L.3    Bai, J.4    Ge, H.Y.5    Liu, P.6
  • 141
    • 24344436378 scopus 로고    scopus 로고
    • Effect of aging on intracellular distribution of abasic (AP) endonuclease 1 in the mouse liver
    • B. Szczesny S. Mitra Effect of aging on intracellular distribution of abasic (AP) endonuclease 1 in the mouse liver Mechanisms of Ageing and Development, 126 ,10 1071- 1078, 2005
    • (2005) Mechanisms of Ageing and Development , vol.126 , Issue.10 , pp. 1071-1078
    • Szczesny, B.1    Mitra, S.2
  • 142
  • 143
    • 48349106989 scopus 로고    scopus 로고
    • APE1 and XRCC3 polymorphisms and myocardial infarction
    • A. Tekeli, S. Isbir, A. Ergen et al., " APE1 and XRCC3 polymorphisms and myocardial infarction," In Vivo, vol. 22, no. 4, pp. 477-480, 2008.
    • (2008) Vivo , vol.22 , Issue.4 , pp. 477-480
    • Tekeli, A.1    Isbir, S.2    Ergen, A.3
  • 144
    • 84863099502 scopus 로고    scopus 로고
    • Functional polymorphisms in XRCC-1 and APE-1 contribute to increased apoptosis and risk of ulcerative colitis, "
    • A. Bardia, S. K. Tiwari, S. Gunisetty et al., " Functional polymorphisms in XRCC-1 and APE-1 contribute to increased apoptosis and risk of ulcerative colitis, " Inflammation Research, vol. 61, no. 4, pp. 359-365, 2012.
    • (2012) Inflammation Research , vol.61 , Issue.4 , pp. 359-365
    • Bardia, A.1    Tiwari, S.K.2    Gunisetty, S.3
  • 145
    • 78650308983 scopus 로고    scopus 로고
    • Inhibition of APE 1/Ref-1 redox activity with APX3330 blocks retinal angiogenesis in vitro and in vivo
    • A. Jiang, H. Gao, M. R. Kelley, and X. Qiao, "Inhibition of APE 1/Ref-1 redox activity with APX3330 blocks retinal angiogenesis in vitro and in vivo," Vision Research, vol. 51, no. 1, pp. 93-100, 2011.
    • (2011) Vision Research , vol.51 , Issue.1 , pp. 93-100
    • Jiang, A.1    Gao, H.2    Kelley, M.R.3    Qiao, X.4
  • 146
    • 0032581277 scopus 로고    scopus 로고
    • Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
    • P. Carmeliet, Y. Dor, J. M. Herbert et al., " Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis, " Nature, vol. 394, no. 6692, pp. 485-490, 1998.
    • (1998) Nature , vol.394 , Issue.6692 , pp. 485-490
    • Carmeliet, P.1    Dor, Y.2    Herbert, J.M.3
  • 147
    • 30744476478 scopus 로고    scopus 로고
    • Retinal angiogenesis in development and disease
    • R. F. Gariano and T. W. Gardner, "Retinal angiogenesis in development and disease, " Nature, vol. 438, no. 7070, pp. 960-966, 2005.
    • (2005) Nature , vol.438 , Issue.7070 , pp. 960-966
    • Gariano, R.F.1    Gardner, T.W.2
  • 148
    • 0032619880 scopus 로고    scopus 로고
    • Review of studies of selected metabolic polymorphisms and cancer
    • A. d'Errico, N. Malats, P. Vineis, and P. Boffetta, " Review of studies of selected metabolic polymorphisms and cancer.," IARC scientific publications, no. 148, pp. 323-393, 1999.
    • (1999) IARC Scientific Publications , Issue.148 , pp. 323-393
    • Derrico, A.1    Malats, N.2    Vineis, P.3    Boffetta, P.4
  • 149
    • 13744261256 scopus 로고    scopus 로고
    • Some drinking-water disinfectants and contaminants, including arsenic
    • IARCWorking Group on the Evaluation of Carcinogenic Risks to Humans, " Some drinking-water disinfectants and contaminants, including arsenic," IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol. 84, pp. 1-477, 2004.
    • (2004) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , vol.84 , pp. 1-477
  • 150
    • 34547598210 scopus 로고    scopus 로고
    • Insights into the carcinogenic mode of action of arsenic
    • A. D. Kligerman and A. H. Tennant, "Insights into the carcinogenic mode of action of arsenic, " Toxicology a nd Applied Pharmacology, vol. 222, no. 3, pp. 281-288, 2007.
    • (2007) Toxicology A Nd Applied Pharmacology , vol.222 , Issue.3 , pp. 281-288
    • Kligerman, A.D.1    Tennant, A.H.2
  • 151
    • 35348907322 scopus 로고    scopus 로고
    • The concentration of selected cancer markers (TPA, TPS, CYFRA 21-1, CEA) in workers occupationally exposed to arsenic (As) and some heavy metals (Pb, Cd) during a two-year observation study
    • A. Szymá nska-Chabowska, J. Antonowicz-Juchniewicz, and R. Andrzejak, " The concentration of selected cancer markers (TPA, TPS, CYFRA 21-1, CEA) in workers occupationally exposed to arsenic (As) and some heavy metals (Pb, Cd) during a two-year observation study, " International Journal of Occupational Medicine and Environmental Health, vol. 20, no. 3, pp. 229-239, 2007.
    • (2007) International Journal of Occupational Medicine and Environmental Health , vol.20 , Issue.3 , pp. 229-239
    • Szymánska-Chabowska, A.1    Antonowicz-Juchniewicz, J.2    Andrzejak, R.3
  • 153
    • 22544482100 scopus 로고    scopus 로고
    • Characterization of themonomethylarsonate reductase and d ehydroascorbate reductase activities of Omega class glutathione transferase variants: Implications for arsenic metabolism and the age-atonset of Alzheimer's and Parkinson's diseases
    • E. M. Schmuck, P. G. Board, A. K.Whitbread et al., " Characterization of themonomethylarsonate reductase and d ehydroascorbate reductase activities of Omega class glutathione transferase variants: Implications for arsenic metabolism and the age-atonset of Alzheimer's and Parkinson's diseases, " Pharmacogenetics and Genomics, vol. 15, no. 7, pp. 493-501, 2005.
    • (2005) Pharmacogenetics and Genomics , vol.15 , Issue.7 , pp. 493-501
    • Schmuck, E.M.1    Board, P.G.2    Whitbread, A.3
  • 156
    • 24644459501 scopus 로고    scopus 로고
    • Arsenic, mode of action at biologically plausible low doses: What are the implications for low dose cancer risk
    • ] E. T. Snow, P. Sykora, T. R. Durham, and C. B. Klein, " Arsenic, mode of action at biologically plausible low doses: what are the implications for low dose cancer risk?" Toxicology and Applied Pharmacology, vol. 207, supplememet 1, no. 2, pp. 557-564, 2005.
    • (2005) Toxicology and Applied Pharmacology , vol.207 , Issue.2 , pp. 557-564
    • Snow, E.T.1    Sykora, P.2    Durham, T.R.3    Klein, C.B.4
  • 158
    • 34047116383 scopus 로고    scopus 로고
    • Association of DNA repair polymorphisms withDNA repair functional outcomes in healthy human subjects
    • P. Vodicka, R. Stetina, V. Polakova et al., " Association of DNA repair polymorphisms withDNA repair functional outcomes in healthy human subjects, " Carcinogenesis, vol. 28, no. 3, pp. 657-664, 2007.
    • (2007) Carcinogenesis , vol.28 , Issue.3 , pp. 657-664
    • Vodicka, P.1    Stetina, R.2    Polakova, V.3
  • 159
    • 0027867973 scopus 로고
    • Beryllium, cadmium, mercury, and exposures in the glass manufacturing industry. Working Group views and expert opinions, Lyon, 9-16 February 1993, "
    • " Beryllium, cadmium, mercury, and exposures in the glass manufacturing industry. Working Group views and expert opinions, Lyon, 9-16 February 1993, " IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol. 58, pp. 1-415, 1993.
    • (1993) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , vol.58 , pp. 1-415
  • 161
    • 0142219722 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of cadmium carcinogenesis
    • M.Waisberg,P. Joseph, B.Hale, andD. Beyersmann, " Molecular and cellular mechanisms of cadmium carcinogenesis," Toxicology, vol. 192, no. 2- 3, pp. 95-117, 2003.
    • (2003) Toxicology , vol.192 , Issue.2-3 , pp. 95-117
    • Waisberg, M.1    Joseph, P.2    Hale, B.3    Beyersmann, D.4
  • 162
    • 33751002324 scopus 로고    scopus 로고
    • Cadmium: Cellular effects, modifications of biomolecules, modulation of DNA repair and genotoxic consequences (a review)
    • G. Bertin D. AverbeckCadmium: Cellular effects, modifications of biomolecules, modulation of DNA repair and genotoxic consequences (a review) Biochimie ,88 , 11, 1549-1559 ,2006.
    • (2006) Biochimie , vol.88 , Issue.11 , pp. 1549-1559
    • Bertin, G.1    Averbeck, D.2
  • 163
    • 67649649748 scopus 로고    scopus 로고
    • Mechanisms of cadmiumcarcinogenesis
    • P. Joseph, "Mechanisms of cadmiumcarcinogenesis, " Toxicology and Applied Pharmacology, vol. 238, no. 3, pp. 272-279, 2009.
    • (2009) Toxicology and Applied Pharmacology , vol.238 , Issue.3 , pp. 272-279
    • Joseph, P.1
  • 164
    • 38049112778 scopus 로고    scopus 로고
    • Early steps in the DNA base excision/single-strand interruption repair pa thway in mammalian cells
    • M. L. Hegde, T. K. Hazra, and S. Mitra, "Early steps in the DNA base excision/single-strand interruption repair pa thway in mammalian cells," Cell Research, vol. 18,no. 1, pp. 27-47, 2008.
    • (2008) Cell Research , vol.18 , Issue.1 , pp. 27-47
    • Hegde, M.L.1    Hazra, T.K.2    Mitra, S.3
  • 166
    • 84935002611 scopus 로고
    • Lead and lead compounds: Lead and inorganic lead compounds
    • "Lead and lead compounds: lead and inorganic lead compounds, " IARC Monographs Evaluation Carcinogenic Risks to Humans, vol. 23, supplement 7, pp. 1-729, 1987.
    • (1987) IARC Monographs Evaluation Carcinogenic Risks to Humans , vol.23 , pp. 1-729
  • 168
    • 3242774357 scopus 로고    scopus 로고
    • Hazards of heavy metal contamination
    • L. Järup, "Hazards of heavy metal contamination, " British Medical Bulletin, vol. 68, pp. 167-182, 2003.
    • (2003) British Medical Bulletin , vol.68 , pp. 167-182
    • Järup, L.1
  • 169
    • 0142119419 scopus 로고    scopus 로고
    • Inorganic lead toxicology
    • J. Patocka and K. Cerńy, "Inorganic lead toxicology, " Acta Medica, vol. 46, no. 2, pp. 65-72, 2003.
    • (2003) Acta Medica , vol.46 , Issue.2 , pp. 65-72
    • Patocka, J.1    Cerńy, K.2
  • 170
    • 54949102363 scopus 로고    scopus 로고
    • Genotoxic effects of environmental exposure to arsenic and lead on children in Region Lagunera, Mexico
    • J. Mé ndez-Gómez, G. Garciá-Vargas, L. López-Carrillo et al., " Genotoxic effects of environmental exposure to arsenic and lead on children in Region Lagunera, Mexico, " Annals of the New York Academy of Sciences, vol. 1140, pp. 358-367, 2008.
    • (2008) Annals of the New York Academy of Sciences , vol.1140 , pp. 358-367
    • Mé Ndez-Gómez, J.1    Garciá-Vargas, G.2    López-Carrillo, L.3
  • 172
    • 33847117649 scopus 로고    scopus 로고
    • Lead promotes abasic site accumulation and co-mutagenesis in mammalian cells by inhibiting themajor abasic endonuclease Ape1
    • D. R. McNeill, H. Wong, A. Narayana, and D. M. Wilson III, " Lead promotes abasic site accumulation and co-mutagenesis in mammalian cells by inhibiting themajor abasic endonuclease Ape1, " Molecular Carcinogenesis, vol. 46, no. 2, pp. 91-99, 2007.
    • (2007) Molecular Carcinogenesis , vol.46 , Issue.2 , pp. 91-99
    • McNeill, D.R.1    Wong, H.2    Narayana, A.3    Wilson, D.M.4
  • 173
    • 0032188756 scopus 로고    scopus 로고
    • Apurinic endonuclease (Ref-1) is induced in mammalian cells by oxidative stress and involved in clastogenic adaptation
    • S. Grö sch, G. Fritz, and B. Kaina, "Apurinic endonuclease (Ref-1) is induced in mammalian cells by oxidative stress and involved in clastogenic adaptation," Cancer Research, vol. 58,no. 19, pp. 4410-4416, 1998.
    • (1998) Cancer Research , vol.58 , Issue.19 , pp. 4410-4416
    • Grö Sch, S.1    Fritz, G.2    Kaina, B.3
  • 174
    • 0032574770 scopus 로고    scopus 로고
    • Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals
    • C. V. Ramana, I. Boldogh, T. Izumi, and S.Mitra, " Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals, " Proceedings of the National Academy of Sciences of the United States of America, vol. 95, no. 9, pp. 5061-5066, 1998.
    • (1998) Proceedings of the National Academy of Sciences of the United States of America , vol.95 , Issue.9 , pp. 5061-5066
    • Ramana, C.V.1    Boldogh, I.2    Izumi, T.3    Mitra, S.4
  • 175
    • 0031002938 scopus 로고    scopus 로고
    • Cancer, cigarette smoking and premature death in Europ e: A review including the Recommendations of European Cancer Experts Consensus Meeting, Helsinki, October 1996
    • P. Boyle, "Cancer, cigarette smoking and premature death in Europ e: a review including the Recommendations of European Cancer Experts Consensus Meeting, Helsinki, October 1996," Lung Cancer, vol. 17, no. 1, pp. 1-60, 1997.
    • (1997) Lung Cancer , vol.17 , Issue.1 , pp. 1-60
    • Boyle, P.1
  • 176
    • 0036333198 scopus 로고    scopus 로고
    • Cigarette smoking and lu ng cancer: Chemical mechanisms and approaches to prevention
    • S. S. Hecht, "Cigarette smoking and lu ng cancer: chemical mechanisms and approaches to prevention," The Lancet Oncology, vol. 3, no. 8, pp. 461-469, 2002.
    • (2002) The Lancet Oncology , vol.3 , Issue.8 , pp. 461-469
    • Hecht, S.S.1
  • 177
    • 0030668586 scopus 로고    scopus 로고
    • The role of DNA repair capacity in susceptibility to lung cancer: A review
    • Q. Wei and M. R. Spitz, "The role of DNA repair capacity in susceptibility to lung cancer: a review," Cancer and Metastasis Reviews, vol. 16, no. 3- 4, pp. 295-307, 1997.
    • (1997) Cancer and Metastasis Reviews , vol.16 , Issue.3-4 , pp. 295-307
    • Wei, Q.1    Spitz, M.R.2
  • 178
    • 0035866403 scopus 로고    scopus 로고
    • Modulation of nucleotide excision repair capacity by XPD polymorphisms in lung cancer patients
    • M. R. Spitz, X. Wu, Y. Wang et al., " Modulation of nucleotide excision repair capacity by XPD polymorphisms in lung cancer patients, " Cancer Research, vol. 61, no. 4, pp. 1354-1357, 2001.
    • (2001) Cancer Research , vol.61 , Issue.4 , pp. 1354-1357
    • Spitz, M.R.1    Wu, X.2    Wang, Y.3
  • 179
    • 0029832418 scopus 로고    scopus 로고
    • ReducedDNA repair capacity in lung cancer patients
    • Q. Wei, L. Cheng, W. K. Hong, andM. R. Spitz, " ReducedDNA repair capacity in lung cancer patients," Cancer Research, vol. 56, no. 18, pp. 4103-4107, 1996.
    • (1996) Cancer Research , vol.56 , Issue.18 , pp. 4103-4107
    • Wei, Q.1    Cheng, L.2    Hong, W.K.3    Spitz, M.R.4
  • 180
    • 0042916149 scopus 로고    scopus 로고
    • Smoking, DNA repair capacity and risk of nonsmall cell lung cancer
    • H. Shen, M. R. Spitz, Y. Qiao et al., " Smoking, DNA repair capacity and risk of nonsmall cell lung cancer," International Journal of Cancer, vol. 107, no. 1, pp. 84-88, 2003.
    • (2003) International Journal of Cancer , vol.107 , Issue.1 , pp. 84-88
    • Shen, H.1    Spitz, M.R.2    Qiao, Y.3
  • 181
    • 33847355195 scopus 로고    scopus 로고
    • Cigarette smoke condensate-induced level of adenomatous polyposis coli blocks long-patch base excision repair in breast epithelial cells
    • C. N. Kundu, R. Balusu, A. S. Jaiswal, C. G. Gairola, and S. Narayan, " Cigarette smoke condensate-induced level of adenomatous polyposis coli blocks long-patch base excision repair in breast epithelial cells, " Oncogene, vol. 26, no. 10, pp. 1428-1438, 2007.
    • (2007) Oncogene , vol.26 , Issue.10 , pp. 1428-1438
    • Kundu, C.N.1    Balusu, R.2    Jaiswal, A.S.3    Gairola, C.G.4    Narayan, S.5
  • 182
    • 84896695117 scopus 로고    scopus 로고
    • Resveratrol mediated cell death in cigarette smoke transformed breast epithelial cells is through induction of p21Waf1/Cip1 and inhibition of longpatchbase excision repair pathway
    • P. Mohapatra, S. R. Satapathy, D. Das et al., " Resveratrol mediated cell death in cigarette smoke transformed breast epithelial cells is through induction of p21Waf1/Cip1 and inhibition of longpatchbase excision repair pathway, " Toxicology and Applied Pharma cology, vol. 275, no. 3, pp. 221-231, 2014.
    • (2014) Toxicology and Applied Pharma Cology , vol.275 , Issue.3 , pp. 221-231
    • Mohapatra, P.1    Satapathy, S.R.2    Das, D.3
  • 183
    • 84875637193 scopus 로고    scopus 로고
    • Adenomatous polyposis coli-mediated accumulation of abasic DNA lesions lead to cigarette smoke condensate-induced neoplastic transformation of normal breast epithelial cells
    • A. S. Jaiswal, H. Panda, C. A. Pampo et al., " Adenomatous polyposis coli-mediated accumulation of abasic dna lesions lead to cigarette smoke condensate-induced neoplastic transformation of normal breast epithelial cells, " Neoplasia, vol. 15, no. 4, pp. 454-460, 2013.
    • (2013) Neoplasia , vol.15 , Issue.4 , pp. 454-460
    • Jaiswal, A.S.1    Panda, H.2    Pampo, C.A.3
  • 184
    • 0031797032 scopus 로고    scopus 로고
    • Ionizing radiation and cancer risk: Evidence from epidemiology
    • E. Ron Ionizing radiation and cancer risk: evidence from epidemiology Radiation Research 150 5 S30-S41 1998.
    • (1998) Radiation Research , vol.150 , Issue.5 , pp. S30-S41
    • Ron, E.1
  • 186
    • 44349138945 scopus 로고    scopus 로고
    • Cancer risks from diagnostic radiology
    • E. J. Hall and D. J. Brenner, "Cancer risks from diagnostic radiology, " British Journal of Radiology, vol. 81, no. 965, pp. 362-378, 2008.
    • (2008) British Journal of Radiology , vol.81 , Issue.965 , pp. 362-378
    • Hall, E.J.1    Brenner, D.J.2
  • 187
    • 77951838449 scopus 로고    scopus 로고
    • Should we be concerned about the rapid increase in CT usage?
    • D. J. Brenner, "Should we be concerned about the rapid increase in CT usage? " Reviews on Environmental Health, vol. 25, no. 1, pp. 63-67, 2010.
    • (2010) Reviews on Environmental Health , vol.25 , Issue.1 , pp. 63-67
    • Brenner, D.J.1


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