Effect of long-term human exposure to environmental heavy metals on the expression of detoxification and DNA repair genes

Environmental Pollution

Volumn 181, Issue , 2013, Pages 226-232

  Al Bakheet, Saleh A ^a   Attafi, Ibraheem M ^a   Maayah, Zaid H ^a   Abd Allah, Adel R ^a   Asiri, Yousif A ^a   Korashy, Hesham M ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Cadmium; DNA adduct; Lead; Mercury; Mining activity

Indexed keywords

CONTROL GROUPS; DNA ADDUCTS; HIGH EXPOSURES; HUMAN EXPOSURES; MALE RESIDENTS; MERCURIES (HG); MINING ACTIVITIES; MRNA EXPRESSION LEVEL;

CADMIUM; DETOXIFICATION; LEAD; MERCURY (METAL); NUCLEIC ACIDS;

GENE EXPRESSION;

CADMIUM; CYTOCHROME P450 1A1; HEAVY METAL; LEAD; MERCURY; MESSENGER RNA;

CADMIUM; DETOXIFICATION; DNA; GENE EXPRESSION; LEAD; MERCURY (ELEMENT); MINING; POLLUTION EFFECT; POLLUTION EXPOSURE;

ADULT; APE1 GENE; ARTICLE; CAT GENE; CONTROLLED STUDY; CYP1A1 GENE; CYP2E1 GENE; CYP3A4 GENE; DETOXIFICATION; DNA REPAIR; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL IMPACT; GAPDH GENE; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GSTA1 GENE; HO 1 GENE; HSP70 GENE; HUMAN; HUMAN EXPERIMENT; LONG TERM EXPOSURE; MALE; MT 1 GENE; NORMAL HUMAN; NQO1 GENE; OGG1 GENE; SAUDI ARABIA; XENOBIOTIC METABOLISM;

CADMIUM; DNA ADDUCT; LEAD; MERCURY; MINING ACTIVITY;

ADULT; CYTOCHROME P-450 CYP1A1; DEOXYGUANOSINE; DNA GLYCOSYLASES; DNA REPAIR; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; GLUTATHIONE TRANSFERASE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (PHOSPHORYLATING); HSP72 HEAT-SHOCK PROTEINS; HUMANS; ISOENZYMES; MALE; METABOLIC DETOXICATION, DRUG; METALLOTHIONEIN; METALS, HEAVY; NAD(P)H DEHYDROGENASE (QUINONE); RNA, MESSENGER; YOUNG ADULT;

MADINAH; MAHD ADH DHAHAB; RIYADH [RIYADH (PRV)]; RIYADH [SAUDI ARABIA]; SAUDI ARABIA;

EID: 84880340355     PISSN: 02697491     EISSN: 18736424     Source Type: Journal    
DOI: 10.1016/j.envpol.2013.06.014     Document Type: Article

References (67)

1. O. Ademuyiwa Effects of sub-chronic low-level lead exposure on the homeostasis of copper and zinc in rat tissues J. Trace Elem. Med. Biol. 24 2010 207 211
2. Agency for Toxic Substances and Disease Registry (ATSDR) The ATSDR 2011, Substance Priority List 2011 U.S. ATSDR Atlanta, GA Available at: http://www.atsdr.cdc.gov/SPL/index.html
3. A.S. Al-Farraj, and M.I. Al-Wabel Evaluation of soil pollution around Mahad AD'Dahab Mine J. Saudi Soc. Agric. Sci. 6 2007 89 106
4. A.S. Al-Farraj, and M.I. Al-Wabel Heavy metals accumulation of some plant species grown on mining area at Mahad AD'Dahab, Saudi Arabia J. Appl. Sci. 7 2007 1170 1175
5. A. Al-Hobaib Heavy metals concentrations and usability of groundwater at Mahd Adh Dhahab gold mine, Saudi Arabia Arab. J. Geosci. 6 2013 259 270
6. E.S. Alicia A method for the measurement of mercury in human whole blood Am. J. Anal. Chem. 2 2011 752 756
7. L.A. Allen Validation and potential mechanisms of red cell distribution width as a prognostic marker in heart failure J. Card. Fail. 16 2010 230 238
8. F. Barbosa Jr. A critical review of biomarkers used for monitoring human exposure to lead: advantages, limitations, and future needs Environ. Health Perspect. 113 2005 1669 1674 (Pubitemid 41794259)
9. J.C. Barrett 12th meeting of the scientific group on methodologies for the safety evaluation of chemicals: susceptibility to environmental hazards Environ. Health Perspect. 105 Suppl. 4 1997 699 737 (Pubitemid 27372955)
10. A. Bazzi Determination of toxic and essential elements in children's blood with inductively coupled plasma-mass spectrometry J. Environ. Monit. 10 2008 1226 1232
11. A.L. Benin High concentrations of heavy metals in neighborhoods near ore smelters in northern Mexico Environ. Health Perspect. 107 1999 279 284 (Pubitemid 29231630)
12. A. Bersenyi Effect of ingested heavy metals (Cd, Pb and Hg) on haematology and serum biochemistry in rabbits Acta Vet. Hung. 51 2003 297 304 (Pubitemid 37026015)
13. D. Beyersmann, and A. Hartwig Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms Arch. Toxicol. 82 2008 493 512
14. Canadian Environmental Protection Act (CEPA) Toxic Substances List - Schedule 1 2012 Available: http://www.ec.gc.ca/lcpe-cepa/default.asp?lang= En&n=0DA2924D-1&wsdoc=4ABEFFC8-5BEC-B57A-F4BF-11069545E434
15. V. Chai Optimization of the PAXgene blood RNA extraction system for gene expression analysis of clinical samples J. Clin. Lab. Anal. 19 2005 182 188 (Pubitemid 41407589)
16. S. Chevillard Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours Oncogene 16 1998 3083 3086 (Pubitemid 28297730)
17. B.F. Coles, and F.F. Kadlubar Human alpha class glutathione S-transferases: genetic polymorphism, expression, and susceptibility to disease Methods Enzymol. 401 2005 9 42 (Pubitemid 43052384)
18. R. Cornelis Sample collection guidelines for trace elements in blood and urine. IUPAC Commission of Toxicology J. Trace Elem. Med. Biol. 10 1996 103 127 (Pubitemid 26235307)
19. C. De Luca The search for reliable biomarkers of disease in multiple chemical sensitivity and other environmental intolerances Int. J. Environ. Res. Public Health 8 2011 2770 2797
20. R.H. Elbekai Ascorbic acid differentially modulates the induction of heme oxygenase-1, NAD(P)H:quinone oxidoreductase 1 and glutathione S-transferase Ya by As(3+), Cd(2+) and Cr(6+) Cancer Lett. 246 2007 54 62 (Pubitemid 44959374)
21. K. Eto, M. Marumoto, and M. Takeya The pathology of methylmercury poisoning (Minamata disease) Neuropathology 30 2010 471 479
22. M. Ferrando Heme oxygenase 1 (HO-1) challenges the angiogenic switch in prostate cancer Angiogenesis 14 2011 467 479
23. M. Filipic, and T.K. Hei Mutagenicity of cadmium in mammalian cells: implication of oxidative DNA damage Mutat. Res. 546 2004 81 91 (Pubitemid 38130222)
24. G. Garcon Biologic markers of oxidative stress and nephrotoxicity as studied in biomonitoring of adverse effects of occupational exposure to lead and cadmium J. Occup. Environ. Med. 46 2004 1180 1186 (Pubitemid 39518499)
25. J.P. Goulle Metal and metalloid multi-elementary ICP-MS validation in whole blood, plasma, urine and hair. Reference values Forensic Sci. Int. 153 2005 39 44
26. Health Canada Guidelines for Canadian Drinking Water Quality - Summary Table 2012 Water, Air and Climate Change Bureau, Healthy Environments and Consumer Safety Branch, Health Canada Ottawa, Ontario
27. A.A. Hegazy Relation between anemia and blood levels of lead, copper, zinc and iron among children BMC Res. Notes 3 2010 133
28. S. Hodgson Kidney disease mortality and environmental exposure to mercury Am. J. Epidemiol. 165 2007 72 77 (Pubitemid 46026211)
29. J. Janik 8-Oxoguanine incision activity is impaired in lung tissues of NSCLC patients with the polymorphism of OGG1 and XRCC1 genes Mutat. Res. 709-710 2011 21 31
30. L. Jarup Hazards of heavy metal contamination Br. Med. Bull. 68 2003 167 182 (Pubitemid 38248496)
31. P. Joseph Mechanisms of cadmium carcinogenesis Toxicol. Appl. Pharmacol. 238 2009 272 279
32. P. Kakkar, and F.N. Jaffery Biological markers for metal toxicity Environ. Toxicol. Pharmacol. 19 2005 335 349 (Pubitemid 39601933)
33. L. Kennedy Hematopoietic lineage transcriptome stability and representation in PAXgene collected peripheral blood utilising SPIA single-stranded cDNA probes for microarray Biomark Insights 3 2008 403 417
34. E. Kobayashi Influence of consumption of cadmium-polluted rice or Jinzu River water on occurrence of renal tubular dysfunction and/or Itai-itai disease Biol. Trace Elem. Res. 127 2009 257 268
35. H.M. Korashy, and A.O. El-Kadi Differential effects of mercury, lead and copper on the constitutive and inducible expression of aryl hydrocarbon receptor (AHR)-regulated genes in cultured hepatoma Hepa 1c1c7 cells Toxicology 201 2004 153 172 (Pubitemid 39023943)
36. H.M. Korashy The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation Chem. Res. Toxicol. 24 2011 1540 1548
37. H.M. Korashy Camel milk modulates the expression of aryl hydrocarbon receptor-regulated genes, Cyp1a1, Nqo1, and Gsta1, in murine hepatoma Hepa 1c1c7 cells J. Biomed. Biotechnol. 2012 2012 782642
38. A. Kumar Reduced expression of DNA repair genes (XRCC1, XPD, and OGG1) in squamous cell carcinoma of head and neck in North India Tumour Biol. 33 2012 111 119
39. J. Li Patient outcome prediction using multiple biomarkers in human melanoma: a clinicopathological study of 118 cases Exp. Ther. Med. 2 2011 131 135
40. Y. Li Risk assessment of heavy metals in soils and vegetables around non-ferrous metals mining and smelting sites, Baiyin, China J. Environ. Sci. (China) 18 2006 1124 1134
41. C.L. Liu Fucoxanthin attenuates rifampin-induced cytochrome P450 3A4 (CYP3A4) and multiple drug resistance 1 (MDR1) gene expression through pregnane X receptor (PXR)-mediated pathways in human hepatoma HepG2 and colon adenocarcinoma LS174T cells Mar. Drugs 10 2012 242 257
42. J. Liu Blood metallothionein transcript as a biomarker for metal sensitivity: low blood metallothionein transcripts in arsenicosis patients from Guizhou, China Environ. Health Perspect. 115 2007 1101 1106 (Pubitemid 47317078)
43. K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 2001 402 408 (Pubitemid 34164012)
44. I. Mahjabeen Novel mutations of OGG1 base excision repair pathway gene in laryngeal cancer patients Fam. Cancer 11 2012 587 593
45. Z. Mazej Heavy metal concentrations in food chain of Lake Velenjsko jezero, Slovenia: an artificial lake from mining Arch. Environ. Contam. Toxicol. 58 2010 998 1007
46. D.R. McNeill Inhibition of Ape1 nuclease activity by lead, iron, and cadmium Environ. Health Perspect. 112 2004 799 804 (Pubitemid 38714779)
47. K.A. Nath Renal oxidant injury and oxidant response induced by mercury Kidney Int. 50 1996 1032 1043 (Pubitemid 26302695)
48. M. Qiao Characterization of soil heavy metal contamination and potential health risk in metropolitan region of northern China Environ. Monit. Assess. 172 2011 353 365
49. S.A. Quandt Heavy metals exposures among Mexican farmworkers in eastern North Carolina Environ. Res. 110 2010 83 88
50. S.A. Rushworth Lipopolysaccharide-induced expression of NAD(P)H:quinone oxidoreductase 1 and heme oxygenase-1 protects against excessive inflammatory responses in human monocytes J. Immunol. 181 2008 6730 6737
51. T. Sakai Determination of lead in plasma, whole blood, and urine by icp-ms and the relationships among the three exposure indices J. Occup. Med. Tox. 51 2003 50 57
52. D. Schwarz Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1: highly stereoselective formation of 17(R), 18(S)-epoxyeicosatetraenoic acid Biochem. Pharmacol. 67 2004 1445 1457 (Pubitemid 38388207)
53. K.J. Senthil Kumar Hepatoprotective effect of lucidone against alcohol-induced oxidative stress in human hepatic HepG2 cells through the up-regulation of HO-1/Nrf-2 antioxidant genes Toxicol. In Vitro 26 2012 700 708
54. H.J. Shin Induction of orphan nuclear receptor Nur77 gene expression and its role in cadmium-induced apoptosis in lung Carcinogenesis 25 2004 1467 1475
55. R.M. Tripathi Blood lead and its effect on Cd, Cu, Zn, Fe and hemoglobin levels of children Sci. Total Environ. 277 2001 161 168 (Pubitemid 32846656)
56. S. Uno Benzo[a]pyrene-induced toxicity: paradoxical protection in Cyp1a1(-/-) knockout mice having increased hepatic BaP-DNA adduct levels Biochem. Biophys. Res. Commun. 289 2001 1049 1056 (Pubitemid 34076296)
57. S. Uno Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation Mol. Pharmacol. 65 2004 1225 1237 (Pubitemid 38543493)
58. + excretion Hum. Exp. Toxicol. 22 2003 237 244 (Pubitemid 36626420)
59. T. Wakai Prognostic significance of NQO1 expression in intrahepatic cholangiocarcinoma Int. J. Clin. Exp. Pathol. 4 2011 363 370
60. Z. Wang Identifying sources and assessing potential risk of heavy metals in soils from direct exposure to children in a mine-impacted city, Changsha, China J. Environ. Qual. 39 2010 1616 1623
61. J.J. Wirth, and R.S. Mijal Adverse effects of low level heavy metal exposure on male reproductive function Syst. Biol. Reprod. Med. 56 2010 147 167
62. H. Yilmaz Analysis of the hematological and biochemical parameters related to lead intoxication J. Forensic Leg. Med. 19 2012 452 454
63. Y. Yin Expression and function of heme oxygenase-1 in human gastric cancer Exp. Biol. Med. (Maywood) 237 2012 362 371
64. Y.J. Yoon KRIBB11 inhibits HSP70 synthesis through inhibition of heat shock factor 1 function by impairing the recruitment of positive transcription elongation factor b to the hsp70 promoter J. Biol. Chem. 286 2011 1737 1747
65. N.H. Zawia Sp1 as a target site for metal-induced perturbations of transcriptional regulation of developmental brain gene expression Brain Res. Dev. Brain Res. 107 1998 291 298 (Pubitemid 28257161)
66. J. Zhang Detection of CYP2E1, a genetic biomarker of susceptibility to benzene metabolism toxicity in immortal human lymphocytes derived from the Han Chinese population Biomed. Environ. Sci. 24 2011 300 309
67. B.N. Zordoky, and A.O. El-Kadi Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases Pharmacol. Ther. 125 2010 446 463