Molecular and genomic approach for understanding the gene-environment interaction between Nrf2 defciency and carcinogenic nickel-induced DNA damage

Oncology Reports

Volumn 28, Issue 6, 2012, Pages 1959-1967

  Kim, Hye Lim ^a,b   Seo, Young Rok ^a,b  

^a Dongguk University   (South Korea)

^b Kyung Hee University Hospital   (South Korea)

Author keywords

DNA damage; Nickel; Nuclear factor eryrhroid 2 related factor 2; Oxidative stress; Pathway analysis; Toxicogenomics

Indexed keywords

HISTONE H2AX; NICKEL; TRANSCRIPTION FACTOR NRF2;

APLP1 GENE; CARCINOGENESIS; CARCINOGENICITY; CAV1 GENE; CELL SURVIVAL; CLSPN GENE; COMET ASSAY; CONFERENCE PAPER; CONTROLLED STUDY; DNA DAMAGE; DNA MICROARRAY; DNA REPAIR; DNA STRAND BREAKAGE; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; FOSL2 GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; HUMAN CELL; MICA GENE; MOLECULAR GENETICS; MUTAGENICITY; NECROSIS; NRF2 GENE; NUCLEOTIDE SEQUENCE; ONCOGENE; OXIDATIVE STRESS; PCAF GENE; PIM2 GENE; PRAME GENE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN PHOSPHORYLATION; RUNX1 GENE; SLC7A6 GENE; UPREGULATION;

ACETATES; CELL LINE, TUMOR; CELL SURVIVAL; CYTOPROTECTION; DNA DAMAGE; DNA REPAIR; GENE-ENVIRONMENT INTERACTION; HUMANS; NF-E2-RELATED FACTOR 2; ORGANOMETALLIC COMPOUNDS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84868103413     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.2057     Document Type: Conference Paper

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