Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair

Environment International

Volumn 43, Issue 1, 2012, Pages 29-36

  García Lestón, Julia ^a   Roma Torres, Joana ^b,c   Vilares, Maria ^d   Pinto, Rui ^e   Prista, João ^c   Teixeira, João Paulo ^b   Mayan, Olga ^b   Conde, João ^f   Pingarilho, Marta ^f   Gaspar, Jorge Francisco ^f   Pásaro, Eduardo ^a   Méndez, Josefina ^a   Laffon, Blanca ^a  

^a UNIVERSITY OF A CORUÑA   (Spain)

^b NATIONAL INSTITUTE OF HEALTH   (Portugal)

^c UNIVERSIDADE NOVA DE LISBOA   (Portugal)

^d NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

^e RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^f NOVA MEDICAL SCHOOL   (Portugal)

Author keywords

Comet assay; Genetic polymorphisms; Genotoxicity; Lead; Micronucleus test; T cell receptor mutation assay

Indexed keywords

CELL MEMBRANES; GENES; LEAD; REPAIR;

COMET ASSAYS; GENETIC POLYMORPHISMS; GENOTOXICITIES; MICRONUCLEUS TEST; MUTATION ASSAYS;

DNA;

APE1 PROTEIN; DNA GLYCOSYLASE MUTY; LEAD; LIG4 PROTEIN; PORPHOBILINOGEN SYNTHASE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; XRCC4 PROTEIN;

BIOASSAY; BIOMARKER; DNA; GENE; GENETIC MARKER; GENOTOXICITY; LEAD; OCCUPATIONAL EXPOSURE; POLLUTION EFFECT; POLYMORPHISM;

APE1 GENE; ARTICLE; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; ETHNIC GROUP; GENE; GENETIC POLYMORPHISM; GENOTOXICITY; HUMAN; LEAD BLOOD LEVEL; LIG4 GENE; MAJOR CLINICAL STUDY; MALE; MICRONUCLEUS TEST; MUTATION RATE; OCCUPATIONAL EXPOSURE; PILOT STUDY; PORTUGUESE; PRIORITY JOURNAL; TOXICOKINETICS; WORKER;

EID: 84860140700     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2012.03.001     Document Type: Article

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