Resveratrol mediated cell death in cigarette smoke transformed breast epithelial cells is through induction of p21Waf1/Cip1 and inhibition of long patch base excision repair pathway

Toxicology and Applied Pharmacology

Volumn 275, Issue 3, 2014, Pages 221-231

  Mohapatra, Purusottam ^a   Satapathy, Shakti Ranjan ^a   Das, Dipon ^a   Siddharth, Sumit ^a   Choudhuri, Tathagata ^b,c   Kundu, Chanakya Nath ^a  

^a KIIT UNIVERSITY   (India)

^b INSTITUTE OF LIFE SCIENCES   (India)

^c VISVA BHARATI UNIVERSITY   (India)

Author keywords

Breast cancer; Cigarette smoke condensate; DNA damage repair; Resveratrol; Transformation

Indexed keywords

CIGARETTE SMOKE; CIGARETTE SMOKE CONDENSATE; CYCLIN DEPENDENT KINASE INHIBITOR 1; HISTONE H2AX; PROTEIN P21; RESVERATROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST CARCINOGENESIS; BREAST EPITHELIUM; CELL DEATH; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; FEMALE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SMOKING; SOLID TUMOR; TUMOR VOLUME; TUMOR XENOGRAFT; WESTERN BLOTTING;

MUS;

BREAST CANCER; CIGARETTE SMOKE CONDENSATE; DNA DAMAGE REPAIR; RESVERATROL; TRANSFORMATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL DEATH; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; FEMALE; FLAP ENDONUCLEASES; HUMANS; MAMMARY GLANDS, HUMAN; MICE; MICE, INBRED BALB C; PROLIFERATING CELL NUCLEAR ANTIGEN; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMOKE; SMOKING; STILBENES; TIME FACTORS; TRANSFECTION; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84896695117     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.01.011     Document Type: Article

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