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Volumn 10, Issue , 2015, Pages 3761-3778

Value of phagocyte function screening for immunotoxicity of nanoparticles in vivo

Author keywords

Cytokines; Immunotoxicity; Nitric oxide generation; Phagocytes; Phagocytosis; Respiratory burst

Indexed keywords

CARBON NANOTUBE; CHEMOTACTIC FACTOR; COMPLEMENT COMPONENT C5A; ELASTASE; ENDOTOXIN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; GAMMA INTERFERON; GOLD NANOPARTICLE; INTERLEUKIN 1; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; LYMPHOCYTE DERIVED CHEMOTACTIC FACTOR; LYMPHOTOXIN; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; NANOPARTICLE; NITRIC OXIDE; POLYSTYRENE; REACTIVE OXYGEN METABOLITE; SILICA NANOPARTICLE; SILVER NANOPARTICLE; TITANIUM DIOXIDE NANOPARTICLE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZINC OXIDE NANOPARTICLE; METAL NANOPARTICLE; OXIDE; SILICON DIOXIDE; SILVER; TITANIUM; TITANIUM DIOXIDE; ZINC OXIDE;

EID: 84930504243     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S83068     Document Type: Article
Times cited : (41)

References (246)
  • 1
    • 34547690726 scopus 로고    scopus 로고
    • Immunological properties of engineered nanomaterials
    • Dobrovolskaia MA, McNeil SE. Immunological properties of engineered nanomaterials. Nat Nanotechnol. 2007;2(8):469–478.
    • (2007) Nat Nanotechnol , vol.2 , Issue.8 , pp. 469-478
    • Dobrovolskaia, M.A.1    McNeil, S.E.2
  • 2
    • 0033367816 scopus 로고    scopus 로고
    • Outdoor air pollution in urban areas and allergic respiratory diseases
    • D’Amato G. Outdoor air pollution in urban areas and allergic respiratory diseases. Monaldi Arch Chest Dis. 1999;54(6):470–474.
    • (1999) Monaldi Arch Chest Dis , vol.54 , Issue.6 , pp. 470-474
    • D’Amato, G.1
  • 3
    • 0036796316 scopus 로고    scopus 로고
    • Association of asthma symptoms with peak particulate air pollution and effect modification by anti-inflammatory medication use
    • Delfino RJ, Zeiger RS, Seltzer JM, Street DH, McLaren CE. Association of asthma symptoms with peak particulate air pollution and effect modification by anti-inflammatory medication use. Environ Health Perspect. 2002;110(10):A607–A617.
    • (2002) Environ Health Perspect , vol.110 , Issue.10 , pp. A607-A617
    • Delfino, R.J.1    Zeiger, R.S.2    Seltzer, J.M.3    Street, D.H.4    McLaren, C.E.5
  • 4
    • 41549129392 scopus 로고    scopus 로고
    • The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles
    • Li N, Xia T, Nel AE. The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles. Free Radic Biol Med. 2008;44(9):1689–1699.
    • (2008) Free Radic Biol Med , vol.44 , Issue.9 , pp. 1689-1699
    • Li, N.1    Xia, T.2    Nel, A.E.3
  • 6
    • 85123316636 scopus 로고    scopus 로고
    • Nanomaterials and nanoparticles: Sources and toxicity
    • Buzea C, Pacheco II, Robbie K. Nanomaterials and nanoparticles: sources and toxicity. Biointerphases. 2007;2(4):MR17–71.
    • (2007) Biointerphases , vol.2 , Issue.4 , pp. MR17-MR71
    • Buzea, C.1    Pacheco, I.I.2    Robbie, K.3
  • 7
    • 83455217479 scopus 로고    scopus 로고
    • Cancer rates after kidney transplantation
    • Sodemann U, Bistrup C, Marckmann P. Cancer rates after kidney transplantation. Dan Med Bull. 2011;58(12):A4342.
    • (2011) Dan Med Bull , vol.58 , Issue.12
    • Sodemann, U.1    Bistrup, C.2    Marckmann, P.3
  • 8
    • 84896471949 scopus 로고    scopus 로고
    • Route-dependent systemic and local immune effects following exposure to solutions prepared from titanium dioxide nanoparticles
    • Auttachoat W, McLoughlin CE, White KL Jr, Smith MJ. Route-dependent systemic and local immune effects following exposure to solutions prepared from titanium dioxide nanoparticles. J Immunotoxicol. 2014;11(3):273–282.
    • (2014) J Immunotoxicol , vol.11 , Issue.3 , pp. 273-282
    • Auttachoat, W.1    McLoughlin, C.E.2    White, K.L.3    Smith, M.J.4
  • 9
    • 51649123914 scopus 로고    scopus 로고
    • Health effects related to nanoparticle exposures: Environmental, health and safety considerations for assessing hazards and risks
    • Warheit DB, Sayes CM, Reed KL, Swain KA. Health effects related to nanoparticle exposures: environmental, health and safety considerations for assessing hazards and risks. Pharmacol Ther. 2008;120(1):35–42.
    • (2008) Pharmacol Ther , vol.120 , Issue.1 , pp. 35-42
    • Warheit, D.B.1    Sayes, C.M.2    Reed, K.L.3    Swain, K.A.4
  • 11
    • 33846221563 scopus 로고    scopus 로고
    • Effect of ultrasmall superparamagnetic iron oxide nanoparticles (Ferumoxtran-10) on human monocyte-macrophages in vitro
    • Müller K, Skepper JN, Posfai M, et al. Effect of ultrasmall superparamagnetic iron oxide nanoparticles (Ferumoxtran-10) on human monocyte-macrophages in vitro. Biomaterials. 2007;28(9):1629–1642.
    • (2007) Biomaterials , vol.28 , Issue.9 , pp. 1629-1642
    • Müller, K.1    Skepper, J.N.2    Posfai, M.3
  • 12
    • 84873725133 scopus 로고    scopus 로고
    • Comparative study of respiratory tract immune toxicity induced by three sterilisation nanoparticles: Silver, zinc oxide and titanium dioxide
    • Liu H, Yang D, Yang H, et al. Comparative study of respiratory tract immune toxicity induced by three sterilisation nanoparticles: silver, zinc oxide and titanium dioxide. J Hazard Mater. 2013;248–249:478–486.
    • (2013) J Hazard Mater , pp. 478-486
    • Liu, H.1    Yang, D.2    Yang, H.3
  • 13
    • 57649243749 scopus 로고    scopus 로고
    • Oxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitro
    • Park EJ, Park K. Oxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitro. Toxicol Lett. 2009; 184(1):18–25.
    • (2009) Toxicol Lett , vol.184 , Issue.1 , pp. 18-25
    • Park, E.J.1    Park, K.2
  • 14
    • 84867711676 scopus 로고    scopus 로고
    • Titanium dioxide induced inflammation in the small intestine
    • Nogueira CM, de Azevedo WM, Dagli ML, et al. Titanium dioxide induced inflammation in the small intestine. World J Gastroenterol. 2012;18(34):4729–4735.
    • (2012) World J Gastroenterol , vol.18 , Issue.34 , pp. 4729-4735
    • Nogueira, C.M.1    De Azevedo, W.M.2    Dagli, M.L.3
  • 15
    • 84925297556 scopus 로고    scopus 로고
    • Particulate nature of inhaled zinc oxide nanoparticles determines systemic effects and mechanisms of pulmonary inflammation in mice
    • Chen JK, Ho CC, Chang H, et al. Particulate nature of inhaled zinc oxide nanoparticles determines systemic effects and mechanisms of pulmonary inflammation in mice. Nanotoxicology. 2015;9:43–53.
    • (2015) Nanotoxicology , vol.9 , pp. 43-53
    • Chen, J.K.1    Ho, C.C.2    Chang, H.3
  • 16
    • 84885871470 scopus 로고    scopus 로고
    • Cell membrane damage and protein interaction induced by copper containing nanoparticles–importance of the metal release process
    • Karlsson HL, Cronholm P, Hedberg Y, Tornberg M, De Battice L, Svedhem S, Wallinder IO. Cell membrane damage and protein interaction induced by copper containing nanoparticles–importance of the metal release process. Toxicology. 2013;313(1):59–69.
    • (2013) Toxicology , vol.313 , Issue.1 , pp. 59-69
    • Karlsson, H.L.1    Cronholm, P.2    Hedberg, Y.3    Tornberg, M.4    De Battice, L.5    Svedhem, S.6    Wallinder, I.O.7
  • 17
    • 84865310538 scopus 로고    scopus 로고
    • The delivered dose: Applying particokinetics to in vitro investigations of nanoparticle internalization by macrophages
    • Ahmad Khanbeigi R, Kumar A, Sadouki F, et al. The delivered dose: Applying particokinetics to in vitro investigations of nanoparticle internalization by macrophages. J Control Release. 2012;162(2):259–266.
    • (2012) J Control Release , vol.162 , Issue.2 , pp. 259-266
    • Ahmad Khanbeigi, R.1    Kumar, A.2    Sadouki, F.3
  • 20
    • 84911092143 scopus 로고    scopus 로고
    • Macrophage heterogeneity in tissues: Phenotypic diversity and functions
    • Gordon S, Pluddemann A, Martinez Estrada F. Macrophage heterogeneity in tissues: phenotypic diversity and functions. Immunol Rev. 2014;262(1):36–55.
    • (2014) Immunol Rev , vol.262 , Issue.1 , pp. 36-55
    • Gordon, S.1    Pluddemann, A.2    Martinez Estrada, F.3
  • 21
    • 34147102301 scopus 로고    scopus 로고
    • Optimum conditions for efficient phagocytosis of rifampicin-loaded PLGA microspheres by alveolar macrophages
    • Hirota K, Hasegawa T, Hinata H, et al. Optimum conditions for efficient phagocytosis of rifampicin-loaded PLGA microspheres by alveolar macrophages. J Control Release. 2007;119(1):69–76.
    • (2007) J Control Release , vol.119 , Issue.1 , pp. 69-76
    • Hirota, K.1    Hasegawa, T.2    Hinata, H.3
  • 22
    • 0022577820 scopus 로고
    • Phagocytosis of latex particles by leucocytes. I. Dependence of phagocytosis on the size and surface potential of particles
    • Kawaguchi H, Koiwai N, Ohtsuka Y, Miyamoto M, Sasakawa S. Phagocytosis of latex particles by leucocytes. I. Dependence of phagocytosis on the size and surface potential of particles. Biomaterials. 1986;7(1):61–66.
    • (1986) Biomaterials , vol.7 , Issue.1 , pp. 61-66
    • Kawaguchi, H.1    Koiwai, N.2    Ohtsuka, Y.3    Miyamoto, M.4    Sasakawa, S.5
  • 23
    • 0025821666 scopus 로고
    • The effect of size of polystyrene particles on their retention within the rat peritoneal compartment, and on their interaction with rat peritoneal macrophages in vitro
    • Seymour L, Schacht E, Duncan R. The effect of size of polystyrene particles on their retention within the rat peritoneal compartment, and on their interaction with rat peritoneal macrophages in vitro. Cell Biol Int Rep. 1991;15(4):277–286.
    • (1991) Cell Biol Int Rep , vol.15 , Issue.4 , pp. 277-286
    • Seymour, L.1    Schacht, E.2    Duncan, R.3
  • 25
    • 51649127081 scopus 로고    scopus 로고
    • The phagocytes: Neutrophils and monocytes
    • Dale DC, Boxer L, Liles WC. The phagocytes: neutrophils and monocytes. Blood. 2008;112(4):935–945.
    • (2008) Blood , vol.112 , Issue.4 , pp. 935-945
    • Dale, D.C.1    Boxer, L.2    Liles, W.C.3
  • 27
    • 0035984827 scopus 로고    scopus 로고
    • Comparative in vitro sensitivities of human immune cell lines, vaginal and cervical epithelial cell lines, and primary cells to candidate microbicides nonoxynol 9, C31G, and sodium dodecyl sulfate
    • Krebs FC, Miller SR, Catalone BJ, Fichorova R, Anderson D, Malamud D, Howett MK, Wigdahl B. Comparative in vitro sensitivities of human immune cell lines, vaginal and cervical epithelial cell lines, and primary cells to candidate microbicides nonoxynol 9, C31G, and sodium dodecyl sulfate. Antimicrob Agents Chemother. 2002;46(7):2292–2298.
    • (2002) Antimicrob Agents Chemother , vol.46 , Issue.7 , pp. 2292-2298
    • Krebs, F.C.1    Miller, S.R.2    Catalone, B.J.3    Fichorova, R.4    Erson, D.5    Malamud, D.6    Howett, M.K.7    Wigdahl, B.8
  • 28
  • 29
    • 0018885287 scopus 로고
    • A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration
    • Falk W, Goodwin RH Jr, Leonard EJ. A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration. J Immunol Methods. 1980;33(3):239–247.
    • (1980) J Immunol Methods , vol.33 , Issue.3 , pp. 239-247
    • Falk, W.1    Goodwin, R.H.2    Leonard, E.J.3
  • 31
    • 84875014253 scopus 로고    scopus 로고
    • A real time chemotaxis assay unveils unique migratory profiles amongst different primary murine macrophages
    • Iqbal AJ, Regan-Komito D, Christou I, et al. A real time chemotaxis assay unveils unique migratory profiles amongst different primary murine macrophages. PLoS One. 2013;8(3):e58744.
    • (2013) Plos One , vol.8 , Issue.3
    • Iqbal, A.J.1    Regan-Komito, D.2    Christou, I.3
  • 32
    • 33645904815 scopus 로고    scopus 로고
    • A new method to quantify phagocytosis and intracellular degradation using green fluorescent protein-labeled Escherichia coli: Comparison of cord blood macrophages and peripheral blood macrophages of healthy adults
    • Gille C, Spring B, Tewes L, Poets CF, Orlikowsky T. A new method to quantify phagocytosis and intracellular degradation using green fluorescent protein-labeled Escherichia coli: comparison of cord blood macrophages and peripheral blood macrophages of healthy adults. Cytometry A. 2006;69(3):152–154.
    • (2006) Cytometry A , vol.69 , Issue.3 , pp. 152-154
    • Gille, C.1    Spring, B.2    Tewes, L.3    Poets, C.F.4    Orlikowsky, T.5
  • 33
    • 0033656445 scopus 로고    scopus 로고
    • Reactive Oxygen Release
    • In: Proudfoot A, Wells T, Power C, editors, Human Press: Totowa
    • Elsner J, Kapp A. Reactive Oxygen Release. In: Proudfoot A, Wells T, Power C, editors. Methods in Molecular Biology: Chemokine Protocols. Human Press: Totowa; 2000:153–157.
    • (2000) Methods in Molecular Biology: Chemokine Protocols , pp. 153-157
    • Elsner, J.1    Kapp, A.2
  • 34
    • 33847783057 scopus 로고    scopus 로고
    • Macrophage biology and immunology: Man is not a mouse
    • discussion 580
    • Schneemann M, Schoeden G. Macrophage biology and immunology: man is not a mouse. J Leukoc Biol. 2007;81(3):579; discussion 580.
    • (2007) J Leukoc Biol , vol.81 , Issue.3 , pp. 579
    • Schneemann, M.1    Schoeden, G.2
  • 35
    • 77649267205 scopus 로고    scopus 로고
    • The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages
    • Daigneault M, Preston JA, Marriott HM, Whyte MK, Dockrell DH. The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages. PLoS One. 2010;5(1):e8668.
    • (2010) Plos One , vol.5 , Issue.1
    • Daigneault, M.1    Preston, J.A.2    Marriott, H.M.3    Whyte, M.K.4    Dockrell, D.H.5
  • 36
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol. 2008;8(12):958–969.
    • (2008) Nat Rev Immunol , vol.8 , Issue.12 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 37
    • 33646514199 scopus 로고    scopus 로고
    • Blood neutrophil activation markers in severe asthma: Lack of inhibition by prednisolone therapy
    • Mann BS, Chung KF. Blood neutrophil activation markers in severe asthma: lack of inhibition by prednisolone therapy. Respir Res. 2006;7:59.
    • (2006) Respir Res , vol.7 , pp. 59
    • Mann, B.S.1    Chung, K.F.2
  • 38
    • 78650880585 scopus 로고    scopus 로고
    • Hydroxylated fullerenes inhibit neutrophil function in fathead minnow (Pimephales promelas Rafinesque, 1820)
    • Jovanović B, Anastasova L, Rowe EW, Palić D. Hydroxylated fullerenes inhibit neutrophil function in fathead minnow (Pimephales promelas Rafinesque, 1820). Aquat Toxicol. 2011;101(2):474–482.
    • (2011) Aquat Toxicol , vol.101 , Issue.2 , pp. 474-482
    • Jovanović, B.1    Anastasova, L.2    Rowe, E.W.3    Ć, D.4
  • 39
    • 80051680980 scopus 로고    scopus 로고
    • Effect of fullerene C60 on functional activity of phagocytic cells
    • Russian
    • Vesnina LÉ, Mamontova TV, Mikitiuk MV, et al. [Effect of fullerene C60 on functional activity of phagocytic cells]. Eksp Klin Farmakol. 2011;74(6):26–29. Russian.
    • (2011) Eksp Klin Farmakol , vol.74 , Issue.6 , pp. 26-29
    • Vesnina, L.1    Mamontova, T.V.2    Mikitiuk, M.V.3
  • 40
    • 0000810758 scopus 로고
    • Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice
    • Steinman RM, Witmer MD. Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice. Proc Natl Acad Sci U S A. 1978;75(10):5132–5136.
    • (1978) Proc Natl Acad Sci U S A , vol.75 , Issue.10 , pp. 5132-5136
    • Steinman, R.M.1    Witmer, M.D.2
  • 41
    • 77949398270 scopus 로고    scopus 로고
    • Donor-strain-derived immature dendritic cell pre-treatment induced hyporesponsiveness against allogeneic antigens
    • Kang HG, Lee JE, Yang SH, et al. Donor-strain-derived immature dendritic cell pre-treatment induced hyporesponsiveness against allogeneic antigens. Immunology. 2010;129(4):567–577.
    • (2010) Immunology , vol.129 , Issue.4 , pp. 567-577
    • Kang, H.G.1    Lee, J.E.2    Yang, S.H.3
  • 42
    • 0029072484 scopus 로고
    • In vitro evaluation of fentanyl and meperidine for immunomodulatory activity
    • House RV, Thomas PT, Bhargava HN. In vitro evaluation of fentanyl and meperidine for immunomodulatory activity. Immunol Lett. 1995;46(1–2):117–124.
    • (1995) Immunol Lett , vol.46 , Issue.12 , pp. 117-124
    • House, R.V.1    Thomas, P.T.2    Bhargava, H.N.3
  • 43
    • 84865720078 scopus 로고    scopus 로고
    • Surface-structure-regulated penetration of nanoparticles across a cell membrane
    • Li Y, Li X, Li Z, Gao H. Surface-structure-regulated penetration of nanoparticles across a cell membrane. Nanoscale. 2012;4(12):3768–3775.
    • (2012) Nanoscale , vol.4 , Issue.12 , pp. 3768-3775
    • Li, Y.1    Li, X.2    Li, Z.3    Gao, H.4
  • 44
    • 0037100530 scopus 로고    scopus 로고
    • MUTZ-3, a human cell line model for the cytokine-induced differentiation of dendritic cells from CD34+ precursors
    • Masterson AJ, Sombroek CC, De Gruijl TD, et al. MUTZ-3, a human cell line model for the cytokine-induced differentiation of dendritic cells from CD34+ precursors. Blood. 2002;100(2):701–703.
    • (2002) Blood , vol.100 , Issue.2 , pp. 701-703
    • Masterson, A.J.1    Sombroek, C.C.2    De Gruijl, T.D.3
  • 45
    • 70449535867 scopus 로고    scopus 로고
    • MUTZ-3-derived dendritic cells as an in vitro alternative model to CD34+ progenitor-derived dendritic cells for testing of chemical sensitizers
    • Nelissen I, Selderslaghs I, Heuvel RV, Witters H, Verheyen GR, Schoeters G. MUTZ-3-derived dendritic cells as an in vitro alternative model to CD34+ progenitor-derived dendritic cells for testing of chemical sensitizers. Toxicol In Vitro. 2009;23(8):1477–1481.
    • (2009) Toxicol in Vitro , vol.23 , Issue.8 , pp. 1477-1481
    • Nelissen, I.1    Selderslaghs, I.2    Heuvel, R.V.3    Witters, H.4    Verheyen, G.R.5    Schoeters, G.6
  • 48
    • 0019175561 scopus 로고
    • Limulus amoebocyte lysate assay for detection and quantitation of endotoxin in a small-volume parenteral product
    • Tsuji K, Steindler KA, Harrison SJ. Limulus amoebocyte lysate assay for detection and quantitation of endotoxin in a small-volume parenteral product. Appl Environ Microbiol. 1980;40(3):533–538.
    • (1980) Appl Environ Microbiol , vol.40 , Issue.3 , pp. 533-538
    • Tsuji, K.1    Steindler, K.A.2    Harrison, S.J.3
  • 49
    • 4243318819 scopus 로고
    • Bacterial endotoxins
    • In: Shier W, Mebs D, editors, New York, NY: Marcel Dekker Inc
    • Hofman J. Bacterial endotoxins. In: Shier W, Mebs D, editors. Handbook of Toxicology. New York, NY: Marcel Dekker Inc.; 1990:655–682.
    • (1990) Handbook of Toxicology , pp. 655-682
    • Hofman, J.1
  • 50
    • 84868573583 scopus 로고    scopus 로고
    • Contamination of nanoparticles by endotoxin: Evaluation of different test methods
    • Smulders S, Kaiser JP, Zuin S, et al. Contamination of nanoparticles by endotoxin: evaluation of different test methods. Part Fibre Toxicol. 2012;9:41.
    • (2012) Part Fibre Toxicol , vol.9 , pp. 41
    • Smulders, S.1    Kaiser, J.P.2    Zuin, S.3
  • 51
    • 79651474507 scopus 로고    scopus 로고
    • Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effects
    • Oostingh GJ, Casals E, Italiani P, et al. Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effects. Part Fibre Toxicol. 2011;8(1):8.
    • (2011) Part Fibre Toxicol , vol.8 , Issue.1 , pp. 8
    • Oostingh, G.J.1    Casals, E.2    Italiani, P.3
  • 52
    • 84884129650 scopus 로고    scopus 로고
    • Endotoxin and Engineered Nanomaterials
    • In: Dobrovolskaia MA, McNeil SE, editors, Republic of Singapore: World Scientific Pub Co Inc
    • Dobrovolskaia MA, McNeil SE. Endotoxin and Engineered Nanomaterials. In: Dobrovolskaia MA, McNeil SE, editors. Handbook of Immunological Properties of Engineered Nanomaterials. Republic of Singapore: World Scientific Pub Co Inc; 2012:77–116.
    • (2012) Handbook of Immunological Properties of Engineered Nanomaterials , pp. 77-116
    • Dobrovolskaia, M.A.1    McNeil, S.E.2
  • 53
    • 34547399502 scopus 로고    scopus 로고
    • Detailed identification of plasma proteins adsorbed on copolymer nanoparticles
    • Cedervall T, Lynch I, Foy M, et al. Detailed identification of plasma proteins adsorbed on copolymer nanoparticles. Angew Chem Int Ed Engl. 2007;46(30):5754–5756.
    • (2007) Angew Chem Int Ed Engl , vol.46 , Issue.30 , pp. 5754-5756
    • Cedervall, T.1    Lynch, I.2    Foy, M.3
  • 54
    • 84873853768 scopus 로고    scopus 로고
    • Biomolecular coronas provide the biological identity of nanosized materials
    • Monopoli MP, Aberg C, Salvati A, Dawson KA. Biomolecular coronas provide the biological identity of nanosized materials. Nat Nanotechnol. 2012;7(12):779–786.
    • (2012) Nat Nanotechnol , vol.7 , Issue.12 , pp. 779-786
    • Monopoli, M.P.1    Aberg, C.2    Salvati, A.3    Dawson, K.A.4
  • 56
    • 84918806355 scopus 로고    scopus 로고
    • Computer simulation of the role of protein corona in cellular delivery of nanoparticles
    • Ding HM, Ma YQ. Computer simulation of the role of protein corona in cellular delivery of nanoparticles. Biomaterials. 2014; 35(30):8703–8710.
    • (2014) Biomaterials , vol.35 , Issue.30 , pp. 8703-8710
    • Ding, H.M.1    Ma, Y.Q.2
  • 57
    • 84887378505 scopus 로고    scopus 로고
    • Altered characteristics of silica nanoparticles in bovine and human serum: The importance of nanomaterial characterization prior to its toxicological evaluation
    • Izak-Nau E, Voetz M, Eiden S, Duschl A, Puntes VF. Altered characteristics of silica nanoparticles in bovine and human serum: the importance of nanomaterial characterization prior to its toxicological evaluation. Part Fibre Toxicol. 2013;10(1):56.
    • (2013) Part Fibre Toxicol , vol.10 , Issue.1 , pp. 56
    • Izak-Nau, E.1    Voetz, M.2    Eiden, S.3    Duschl, A.4    Puntes, V.F.5
  • 58
    • 84867783533 scopus 로고    scopus 로고
    • Molecular interaction of poly(Acrylic acid) gold nanoparticles with human fibrinogen
    • Deng ZJ, Liang M, Toth I, Monteiro MJ, Minchin RF. Molecular interaction of poly(acrylic acid) gold nanoparticles with human fibrinogen. ACS Nano. 2012;6(10):8962–8969.
    • (2012) ACS Nano , vol.6 , Issue.10 , pp. 8962-8969
    • Deng, Z.J.1    Liang, M.2    Toth, I.3    Monteiro, M.J.4    Minchin, R.F.5
  • 60
    • 79959389580 scopus 로고    scopus 로고
    • Binding of polystyrene and carbon black nanoparticles to blood serum proteins
    • Fertsch-Gapp S, Semmler-Behnke M, Wenk A, Kreyling WG. Binding of polystyrene and carbon black nanoparticles to blood serum proteins. Inhal Toxicol. 2011;23(8):468–475.
    • (2011) Inhal Toxicol , vol.23 , Issue.8 , pp. 468-475
    • Fertsch-Gapp, S.1    Semmler-Behnke, M.2    Wenk, A.3    Kreyling, W.G.4
  • 61
    • 10044277018 scopus 로고    scopus 로고
    • Protein adsorption onto silica nanoparticles: Conformational changes depend on the particles’ curvature and the protein stability
    • Lundqvist M, Sethson I, Jonsson BH. Protein adsorption onto silica nanoparticles: conformational changes depend on the particles’ curvature and the protein stability. Langmuir. 2004;20(24):10639–10647.
    • (2004) Langmuir , vol.20 , Issue.24 , pp. 10639-10647
    • Lundqvist, M.1    Sethson, I.2    Jonsson, B.H.3
  • 62
    • 84876045121 scopus 로고    scopus 로고
    • Plasma protein binding of positively and negatively charged polymer-coated gold nanoparticles elicits different biological responses
    • Deng ZJ, Liang M, Toth I, Monteiro M, Minchin RF. Plasma protein binding of positively and negatively charged polymer-coated gold nanoparticles elicits different biological responses. Nanotoxicology. 2013;7(3):314–322.
    • (2013) Nanotoxicology , vol.7 , Issue.3 , pp. 314-322
    • Deng, Z.J.1    Liang, M.2    Toth, I.3    Monteiro, M.4    Minchin, R.F.5
  • 63
    • 79952302512 scopus 로고    scopus 로고
    • Physical-chemical aspects of protein corona: Relevance to in vitro and in vivo biological impacts of nanoparticles
    • Monopoli MP, Walczyk D, Campbell A, et al. Physical-chemical aspects of protein corona: relevance to in vitro and in vivo biological impacts of nanoparticles. J Am Chem Soc. 2011;133(8):2525–2534.
    • (2011) J am Chem Soc , vol.133 , Issue.8 , pp. 2525-2534
    • Monopoli, M.P.1    Walczyk, D.2    Campbell, A.3
  • 64
    • 80053313445 scopus 로고    scopus 로고
    • The evolution of the protein corona around nanoparticles: A test study
    • Lundqvist M, Stigler J, Cedervall T, et al. The evolution of the protein corona around nanoparticles: a test study. ACS Nano. 2011;5(9):7503–7509.
    • (2011) ACS Nano , vol.5 , Issue.9 , pp. 7503-7509
    • Lundqvist, M.1    Stigler, J.2    Cedervall, T.3
  • 65
    • 84886447813 scopus 로고    scopus 로고
    • The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes
    • Wang F, Yu L, Monopoli MP, et al. The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes. Nanomedicine. 2013;9(8):1159–1168.
    • (2013) Nanomedicine , vol.9 , Issue.8 , pp. 1159-1168
    • Wang, F.1    Yu, L.2    Monopoli, M.P.3
  • 66
    • 79955713975 scopus 로고    scopus 로고
    • BSA adsorption on differently charged polystyrene nanoparticles using isothermal titration calorimetry and the influence on cellular uptake
    • Baier G, Costa C, Zeller A, et al. BSA adsorption on differently charged polystyrene nanoparticles using isothermal titration calorimetry and the influence on cellular uptake. Macromol Biosci. 2011;11(5):628–638.
    • (2011) Macromol Biosci , vol.11 , Issue.5 , pp. 628-638
    • Baier, G.1    Costa, C.2    Zeller, A.3
  • 67
    • 84885466820 scopus 로고    scopus 로고
    • Comparative study of ZnO and TiO2 nanoparticles: Physicochemical characterisation and toxicological effects on human colon carcinoma cells
    • De Angelis I, Barone F, Zijno A, et al. Comparative study of ZnO and TiO2 nanoparticles: physicochemical characterisation and toxicological effects on human colon carcinoma cells. Nanotoxicology. 2013;7(8): 1361–1372.
    • (2013) Nanotoxicology , vol.7 , Issue.8 , pp. 1361-1372
    • De Angelis, I.1    Barone, F.2    Zijno, A.3
  • 68
    • 84882535911 scopus 로고    scopus 로고
    • Effects of serum on cytotoxicity of nano-and micro-sized ZnO particles
    • Hsiao IL, Huang YJ. Effects of serum on cytotoxicity of nano-and micro-sized ZnO particles. J Nanopart Res. 2013;15:1829.
    • (2013) J Nanopart Res , vol.15 , pp. 1829
    • Hsiao, I.L.1    Huang, Y.J.2
  • 69
    • 84907478677 scopus 로고    scopus 로고
    • Effects of water and cell culture media on the physicochemical properties of ZnMgO nanoparticles and their toxicity toward mammalian cells
    • Vidic J, Haque F, Guigner JM, Vidy A, Chevalier C, Stankic S. Effects of water and cell culture media on the physicochemical properties of ZnMgO nanoparticles and their toxicity toward mammalian cells. Langmuir. 2014;30(38):11366–11374.
    • (2014) Langmuir , vol.30 , Issue.38 , pp. 11366-11374
    • Vidic, J.1    Haque, F.2    Guigner, J.M.3    Vidy, A.4    Chevalier, C.5    Stankic, S.6
  • 70
    • 84902013170 scopus 로고    scopus 로고
    • Protein coronas suppress the hemolytic activity of hydrophilic and hydrophobic nanoparticles
    • Saha K, Moyano DF, Rotello VM. Protein coronas suppress the hemolytic activity of hydrophilic and hydrophobic nanoparticles. Mater Horiz. 2014;2014(1):102–105.
    • (2014) Mater Horiz , vol.2014 , Issue.1 , pp. 102-105
    • Saha, K.1    Moyano, D.F.2    Rotello, V.M.3
  • 71
    • 84906238490 scopus 로고    scopus 로고
    • Nanoparticle-cell interactions: Molecular structure of the protein corona and cellular outcomes
    • Fleischer CC, Payne CK. Nanoparticle-cell interactions: molecular structure of the protein corona and cellular outcomes. Acc Chem Res. 2014;47(8):2651–2659.
    • (2014) Acc Chem Res , vol.47 , Issue.8 , pp. 2651-2659
    • Fleischer, C.C.1    Payne, C.K.2
  • 72
    • 82255191648 scopus 로고    scopus 로고
    • Uptake of nanoparticles by alveolar macrophages is triggered by surfactant protein A
    • Ruge CA, Kirch J, Cañadas O, et al. Uptake of nanoparticles by alveolar macrophages is triggered by surfactant protein A. Nanomedicine. 2011;7(6):690–693.
    • (2011) Nanomedicine , vol.7 , Issue.6 , pp. 690-693
    • Ruge, C.A.1    Kirch, J.2    Cañadas, O.3
  • 73
    • 82355182186 scopus 로고    scopus 로고
    • Evaluation of the cytotoxic and inflammatory potential of differentially shaped zinc oxide nanoparticles
    • Heng BC, Zhao X, Tan EC, et al. Evaluation of the cytotoxic and inflammatory potential of differentially shaped zinc oxide nanoparticles. Arch Toxicol. 2011;85(12):1517–1528.
    • (2011) Arch Toxicol , vol.85 , Issue.12 , pp. 1517-1528
    • Heng, B.C.1    Zhao, X.2    Tan, E.C.3
  • 74
    • 84876059352 scopus 로고    scopus 로고
    • Screening of different metal oxide nanoparticles reveals selective toxicity and inflammatory potential of silica nanoparticles in lung epithelial cells and macrophages
    • Panas A, Marquardt C, Nalcaci O, et al. Screening of different metal oxide nanoparticles reveals selective toxicity and inflammatory potential of silica nanoparticles in lung epithelial cells and macrophages. Nanotoxicology. 2013;7(3):259–273.
    • (2013) Nanotoxicology , vol.7 , Issue.3 , pp. 259-273
    • Panas, A.1    Marquardt, C.2    Nalcaci, O.3
  • 75
    • 84905273117 scopus 로고    scopus 로고
    • Complement activation by carbon nanotubes and its influence on the phagocytosis and cytokine response by macrophages
    • Pondman KM, Sobik M, Nayak A, et al. Complement activation by carbon nanotubes and its influence on the phagocytosis and cytokine response by macrophages. Nanomedicine. 2014;10(6):1287–1299.
    • (2014) Nanomedicine , vol.10 , Issue.6 , pp. 1287-1299
    • Pondman, K.M.1    Sobik, M.2    Nayak, A.3
  • 76
    • 79951920918 scopus 로고    scopus 로고
    • Proteins of the innate immune system crystallize on carbon nanotubes but are not activated
    • Ling WL, Biro A, Bally I, et al. Proteins of the innate immune system crystallize on carbon nanotubes but are not activated. ACS Nano. 2011;5(2):730–737.
    • (2011) ACS Nano , vol.5 , Issue.2 , pp. 730-737
    • Ling, W.L.1    Biro, A.2    Bally, I.3
  • 77
    • 78650606928 scopus 로고    scopus 로고
    • Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation
    • Deng ZJ, Liang M, Monteiro M, Toth I, Minchin RF. Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation. Nat Nanotechnol. 2011;6(1):39–44.
    • (2011) Nat Nanotechnol , vol.6 , Issue.1 , pp. 39-44
    • Deng, Z.J.1    Liang, M.2    Monteiro, M.3    Toth, I.4    Minchin, R.F.5
  • 78
    • 84906101721 scopus 로고    scopus 로고
    • Protein corona composition does not accurately predict hematocompatibility of colloidal gold nanoparticles
    • Dobrovolskaia MA, Neun BW, Man S, et al. Protein corona composition does not accurately predict hematocompatibility of colloidal gold nanoparticles. Nanomedicine. 2014;10(7):1453–1463.
    • (2014) Nanomedicine , vol.10 , Issue.7 , pp. 1453-1463
    • Dobrovolskaia, M.A.1    Neun, B.W.2    Man, S.3
  • 79
    • 78649457184 scopus 로고    scopus 로고
    • ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies
    • Hinderliter PM, Minard KR, Orr G, et al. ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies. Part Fibre Toxicol. 2010;7(1):36.
    • (2010) Part Fibre Toxicol , vol.7 , Issue.1 , pp. 36
    • Hinderliter, P.M.1    Minard, K.R.2    Orr, G.3
  • 80
    • 84870318900 scopus 로고    scopus 로고
    • Particokinetics: Computational analysis of the superparamagnetic iron oxide nanoparticles deposition process
    • Cárdenas WH, Mamani JB, Sibov TT, Caous CA, Amaro E Jr, Gamarra LF. Particokinetics: computational analysis of the superparamagnetic iron oxide nanoparticles deposition process. Int J Nanomedicine. 2012;7:2699–2712.
    • (2012) Int J Nanomedicine , vol.7 , pp. 2699-2712
    • Cárdenas, W.H.1    Mamani, J.B.2    Sibov, T.T.3    Caous, C.A.4    Amaro, E.5    Gamarra, L.F.6
  • 83
    • 79960132035 scopus 로고    scopus 로고
    • The effect of sedimentation and diffusion on cellular uptake of gold nanoparticles
    • Cho EC, Zhang Q, Xia Y. The effect of sedimentation and diffusion on cellular uptake of gold nanoparticles. Nat Nanotechnol. 2011;6(6): 385–391.
    • (2011) Nat Nanotechnol , vol.6 , Issue.6 , pp. 385-391
    • Cho, E.C.1    Zhang, Q.2    Xia, Y.3
  • 84
    • 85027958231 scopus 로고    scopus 로고
    • Comparison of two in vitro systems to assess cellular effects of nanoparticles-containing aerosols
    • Fröhlich E, Bonstingl G, Höfler A, et al. Comparison of two in vitro systems to assess cellular effects of nanoparticles-containing aerosols. Toxicol In Vitro. 2013;27(1):409–417.
    • (2013) Toxicol in Vitro , vol.27 , Issue.1 , pp. 409-417
    • Fröhlich, E.1    Bonstingl, G.2    Höfler, A.3
  • 85
    • 77955222448 scopus 로고    scopus 로고
    • A dose-controlled system for air-liquid interface cell exposure and application to zinc oxide nanoparticles
    • Lenz AG, Karg E, Lentner B, et al. A dose-controlled system for air-liquid interface cell exposure and application to zinc oxide nanoparticles. Part Fibre Toxicol. 2009;6:32.
    • (2009) Part Fibre Toxicol , vol.6 , pp. 32
    • Lenz, A.G.1    Karg, E.2    Lentner, B.3
  • 86
    • 84880907683 scopus 로고    scopus 로고
    • A compact and portable deposition chamber to study nanoparticles in air-exposed tissue
    • Mertes P, Praplan AP, Künzi L, et al. A compact and portable deposition chamber to study nanoparticles in air-exposed tissue. J Aerosol Med Pulm Drug Deliv. 2013;26(4):228–235.
    • (2013) J Aerosol Med Pulm Drug Deliv , vol.26 , Issue.4 , pp. 228-235
    • Mertes, P.1    Praplan, A.P.2    Künzi, L.3
  • 87
    • 48749100334 scopus 로고    scopus 로고
    • A novel exposure system for the efficient and controlled deposition of aerosol particles onto cell cultures
    • Savi M, Kalberer M, Lang D, et al. A novel exposure system for the efficient and controlled deposition of aerosol particles onto cell cultures. Environ Sci Technol. 2008;42(15):5667–5674.
    • (2008) Environ Sci Technol , vol.42 , Issue.15 , pp. 5667-5674
    • Savi, M.1    Kalberer, M.2    Lang, D.3
  • 88
    • 0036132641 scopus 로고    scopus 로고
    • Deposition of fine and ultrafine aerosol particles during exposure at the air/cell interface
    • Tippe A, Heinzmann U, Roth C. Deposition of fine and ultrafine aerosol particles during exposure at the air/cell interface. J Aerosol Sci. 2002;33(2):207–218.
    • (2002) J Aerosol Sci , vol.33 , Issue.2 , pp. 207-218
    • Tippe, A.1    Heinzmann, U.2    Roth, C.3
  • 89
    • 84870379698 scopus 로고    scopus 로고
    • Multifactorial determinants that govern nanoparticle uptake by human endothelial cells under flow
    • Samuel SP, Jain N, O’Dowd F, et al. Multifactorial determinants that govern nanoparticle uptake by human endothelial cells under flow. Int J Nanomedicine. 2012;7:2943–2956.
    • (2012) Int J Nanomedicine , vol.7 , pp. 2943-2956
    • Samuel, S.P.1    Jain, N.2    O’Dowd, F.3
  • 90
    • 58149267870 scopus 로고    scopus 로고
    • Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line
    • Monteiro-Riviere NA, Inman AO, Zhang LW. Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line. Toxicol Appl Pharmacol. 2009;234(2):222–235.
    • (2009) Toxicol Appl Pharmacol , vol.234 , Issue.2 , pp. 222-235
    • Monteiro-Riviere, N.A.1    Inman, A.O.2    Zhang, L.W.3
  • 91
    • 78650468929 scopus 로고    scopus 로고
    • Internalization of carbon black and maghemite iron oxide nanoparticle mixtures leads to oxidant production
    • Berg JM, Ho S, Hwang W, et al. Internalization of carbon black and maghemite iron oxide nanoparticle mixtures leads to oxidant production. Chem Res Toxicol. 2010;23(12):1874–1882.
    • (2010) Chem Res Toxicol , vol.23 , Issue.12 , pp. 1874-1882
    • Berg, J.M.1    Ho, S.2    Hwang, W.3
  • 92
    • 67650869764 scopus 로고    scopus 로고
    • Confounding experimental considerations in nanogenotoxicology
    • Doak SH, Griffiths SM, Manshian B, et al. Confounding experimental considerations in nanogenotoxicology. Mutagenesis. 2009;24(4): 285–293.
    • (2009) Mutagenesis , vol.24 , Issue.4 , pp. 285-293
    • Doak, S.H.1    Griffiths, S.M.2    Manshian, B.3
  • 93
    • 67349284747 scopus 로고    scopus 로고
    • Current in vitro methods in nanoparticle risk assessment: Limitations and challenges
    • Kroll A, Pillukat MH, Hahn D, Schnekenburger J. Current in vitro methods in nanoparticle risk assessment: limitations and challenges. Eur J Pharm Biopharm. 2009;72(2):370–377.
    • (2009) Eur J Pharm Biopharm , vol.72 , Issue.2 , pp. 370-377
    • Kroll, A.1    Pillukat, M.H.2    Hahn, D.3    Schnekenburger, J.4
  • 94
    • 77749315395 scopus 로고    scopus 로고
    • The suitability of different cellular in vitro immunotoxicity and genotoxicity methods for the analysis of nanoparticle-induced events
    • Pfaller T, Colognato R, Nelissen I, et al. The suitability of different cellular in vitro immunotoxicity and genotoxicity methods for the analysis of nanoparticle-induced events. Nanotoxicology. 2010;4(1):52–72.
    • (2010) Nanotoxicology , vol.4 , Issue.1 , pp. 52-72
    • Pfaller, T.1    Colognato, R.2    Nelissen, I.3
  • 95
    • 70350503605 scopus 로고    scopus 로고
    • Development of in vitro systems for nanotoxicology: Methodological considerations
    • Stone V, Johnston H, Schins RP. Development of in vitro systems for nanotoxicology: methodological considerations. Crit Rev Toxicol. 2009;39(7):613–626.
    • (2009) Crit Rev Toxicol , vol.39 , Issue.7 , pp. 613-626
    • Stone, V.1    Johnston, H.2    Schins, R.P.3
  • 96
    • 84863802840 scopus 로고    scopus 로고
    • Inhibition of enzyme activity by nanomaterials: Potential mechanisms and implications for nanotoxicity testing
    • Maccormack TJ, Clark RJ, Dang MK, et al. Inhibition of enzyme activity by nanomaterials: potential mechanisms and implications for nanotoxicity testing. Nanotoxicology. 2012;6(5):514–525.
    • (2012) Nanotoxicology , vol.6 , Issue.5 , pp. 514-525
    • Maccormack, T.J.1    Clark, R.J.2    Dang, M.K.3
  • 97
    • 84897490257 scopus 로고    scopus 로고
    • Widespread nanoparticle-assay interference: Implications for nanotoxicity testing
    • Ong KJ, MacCormack TJ, Clark RJ, et al. Widespread nanoparticle-assay interference: implications for nanotoxicity testing. PLoS One. 2014;9(3):e90650.
    • (2014) Plos One , vol.9 , Issue.3
    • Ong, K.J.1    Maccormack, T.J.2    Clark, R.J.3
  • 98
    • 80051582306 scopus 로고    scopus 로고
    • Analytical characterization of gold nanoparticle primary particles, aggregates, agglomerates, and agglomerated aggregates
    • Keene AM, Tyner KM. Analytical characterization of gold nanoparticle primary particles, aggregates, agglomerates, and agglomerated aggregates. Journal of Nanoparticle Research. 2011;13(8): 3465–3481.
    • (2011) Journal of Nanoparticle Research , vol.13 , Issue.8 , pp. 3465-3481
    • Keene, A.M.1    Tyner, K.M.2
  • 99
    • 26944487638 scopus 로고    scopus 로고
    • Porous gold nanospheres by controlled transmetalation reaction: A novel material for application in cell imaging
    • Shukla S, Priscilla A, Banerjee M, et al. Porous gold nanospheres by controlled transmetalation reaction: a novel material for application in cell imaging. Chem Mater. 2005;17(20):5000–5005.
    • (2005) Chem Mater , vol.17 , Issue.20 , pp. 5000-5005
    • Shukla, S.1    Priscilla, A.2    Banerjee, M.3
  • 100
    • 44449125568 scopus 로고    scopus 로고
    • Single walled carbon nanotubes induce indirect cytotoxicity by medium depletion in A549 lung cells
    • Casey A, Herzog E, Lyng FM, Byrne HJ, Chambers G, Davoren M. Single walled carbon nanotubes induce indirect cytotoxicity by medium depletion in A549 lung cells. Toxicol Lett. 2008;179(2):78–84.
    • (2008) Toxicol Lett , vol.179 , Issue.2 , pp. 78-84
    • Casey, A.1    Herzog, E.2    Lyng, F.M.3    Byrne, H.J.4    Chambers, G.5    Davoren, M.6
  • 101
    • 34547382496 scopus 로고    scopus 로고
    • Fluorescence modulation of acridine and coumarin dyes by silver nanoparticles
    • Sabatini CA, Pereira RV, Gehlen MH. Fluorescence modulation of acridine and coumarin dyes by silver nanoparticles. J Fluoresc. 2007;17(4): 377–382.
    • (2007) J Fluoresc , vol.17 , Issue.4 , pp. 377-382
    • Sabatini, C.A.1    Pereira, R.V.2    Gehlen, M.H.3
  • 102
    • 84886397566 scopus 로고    scopus 로고
    • Important issues in the cytotoxicity screening of nano-sized materials
    • Fröhlich E, Meindl C, Pieber TR. Important issues in the cytotoxicity screening of nano-sized materials. EURO-NanoTox Letters. 2010;1: 1–6.
    • (2010) Euro-Nanotox Letters , vol.1 , pp. 1-6
    • Fröhlich, E.1    Meindl, C.2    Pieber, T.R.3
  • 103
    • 84930507473 scopus 로고    scopus 로고
    • SCENIHR working group [webpage on the Internet]. The appropriateness of existing methodologies to assess the potential risks associated with engineered and adventitious products of nanotechnologies; 2006. Available from, Accessed January 1
    • SCENIHR working group [webpage on the Internet]. The appropriateness of existing methodologies to assess the potential risks associated with engineered and adventitious products of nanotechnologies; 2006. Available from: http://ec.europa.eu/health/ph_risk/committees/04_scenihr/docs/scenihr_o_003b.pdf. Accessed January 1, 2015.
    • (2015)
  • 104
    • 84930506264 scopus 로고    scopus 로고
    • Alterations of pulmonary function
    • In: Huether S, McCance K, editors, 5th ed. St Louis, MO: Elsevier
    • Brashers V. Alterations of pulmonary function. In: Huether S, McCance K, editors. Understanding Pathophysiology. 5th ed. St Louis, MO: Elsevier; 2012:678–699.
    • (2012) Understanding Pathophysiology , pp. 678-699
    • Brashers, V.1
  • 105
    • 68549135126 scopus 로고    scopus 로고
    • Cytotoxicity of nanoparticles independent from oxidative stress
    • Fröhlich E, Samberger C, Kueznik T, et al. Cytotoxicity of nanoparticles independent from oxidative stress. J Toxicol Sci. 2009;34(4): 363–375.
    • (2009) J Toxicol Sci , vol.34 , Issue.4 , pp. 363-375
    • Fröhlich, E.1    Samberger, C.2    Kueznik, T.3
  • 106
    • 42649099670 scopus 로고    scopus 로고
    • Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways
    • Xia T, Kovochich M, Liong M, Zink JI, Nel AE. Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways. ACS Nano. 2008;2(1):85–96.
    • (2008) ACS Nano , vol.2 , Issue.1 , pp. 85-96
    • Xia, T.1    Kovochich, M.2    Liong, M.3    Zink, J.I.4    Nel, A.E.5
  • 107
    • 77954912731 scopus 로고    scopus 로고
    • Effect of ultrafine zinc oxide (ZnO) nanoparticles on induction of oral tolerance in mice
    • Matsumura M, Takasu N, Nagata M, Nakamura K, Kawai M, Yoshino S. Effect of ultrafine zinc oxide (ZnO) nanoparticles on induction of oral tolerance in mice. J Immunotoxicol. 2010;7(3):232–237.
    • (2010) J Immunotoxicol , vol.7 , Issue.3 , pp. 232-237
    • Matsumura, M.1    Takasu, N.2    Nagata, M.3    Nakamura, K.4    Kawai, M.5    Yoshino, S.6
  • 108
    • 84874577394 scopus 로고    scopus 로고
    • In vivo study of spherical gold nanoparticles: Inflammatory effects and distribution in mice
    • Chen H, Dorrigan A, Saad S, Hare DJ, Cortie MB, Valenzuela SM. In vivo study of spherical gold nanoparticles: inflammatory effects and distribution in mice. PLoS One. 2013;8(2):e58208.
    • (2013) Plos One , vol.8 , Issue.2
    • Chen, H.1    Dorrigan, A.2    Saad, S.3    Hare, D.J.4    Cortie, M.B.5    Valenzuela, S.M.6
  • 109
    • 84873366290 scopus 로고    scopus 로고
    • Gold nanoparticles downregulate interleukin-1β-induced pro-inflammatory responses
    • Sumbayev VV, Yasinska IM, Garcia CP, et al. Gold nanoparticles downregulate interleukin-1β-induced pro-inflammatory responses. Small. 2013;9(3):472–477.
    • (2013) Small , vol.9 , Issue.3 , pp. 472-477
    • Sumbayev, V.V.1    Yasinska, I.M.2    Garcia, C.P.3
  • 110
    • 80052058658 scopus 로고    scopus 로고
    • Uptake of gold nanoparticles in murine macrophage cells without cytotoxicity or production of pro-inflammatory mediators
    • Zhang Q, Hitchins VM, Schrand AM, Hussain SM, Goering PL. Uptake of gold nanoparticles in murine macrophage cells without cytotoxicity or production of pro-inflammatory mediators. Nanotoxicology. 2011;5(3):284–295.
    • (2011) Nanotoxicology , vol.5 , Issue.3 , pp. 284-295
    • Zhang, Q.1    Hitchins, V.M.2    Schrand, A.M.3    Hussain, S.M.4    Goering, P.L.5
  • 111
    • 28044446787 scopus 로고    scopus 로고
    • Biocompatibility of gold nanoparticles and their endocytotic fate inside the cellular compartment: A microscopic overview
    • Shukla R, Bansal V, Chaudhary M, Basu A, Bhonde RR, Sastry M. Biocompatibility of gold nanoparticles and their endocytotic fate inside the cellular compartment: a microscopic overview. Langmuir. 2005;21(23):10644–10654.
    • (2005) Langmuir , vol.21 , Issue.23 , pp. 10644-10654
    • Shukla, R.1    Bansal, V.2    Chaudhary, M.3    Basu, A.4    Bhonde, R.R.5    Sastry, M.6
  • 112
    • 75049086020 scopus 로고    scopus 로고
    • Analysis of the toxicity of gold nano particles on the immune system: Effect on dendritic cell functions
    • Villiers C, Freitas H, Couderc R, Villiers MB, Marche P. Analysis of the toxicity of gold nano particles on the immune system: effect on dendritic cell functions. J Nanopart Res. 2010;12(1):55–60.
    • (2010) J Nanopart Res , vol.12 , Issue.1 , pp. 55-60
    • Villiers, C.1    Freitas, H.2    Couderc, R.3    Villiers, M.B.4    Marche, P.5
  • 113
    • 65549088539 scopus 로고    scopus 로고
    • Single-walled and multi-walled carbon nanotubes promote allergic immune responses in mice
    • Nygaard UC, Hansen JS, Samuelsen M, Alberg T, Marioara CD, Løvik M. Single-walled and multi-walled carbon nanotubes promote allergic immune responses in mice. Toxicol Sci. 2009;109(1): 113–123.
    • (2009) Toxicol Sci , vol.109 , Issue.1 , pp. 113-123
    • Nygaard, U.C.1    Hansen, J.S.2    Samuelsen, M.3    Alberg, T.4    Marioara, C.D.5    Løvik, M.6
  • 114
    • 77249092583 scopus 로고    scopus 로고
    • Adjuvant effect of zinc oxide on Th2 but not Th1 immune responses in mice
    • Matsumura M, Nagata M, Nakamura K, et al. Adjuvant effect of zinc oxide on Th2 but not Th1 immune responses in mice. Immunopharmacol Immunotoxicol. 2010;32(1):56–62.
    • (2010) Immunopharmacol Immunotoxicol , vol.32 , Issue.1 , pp. 56-62
    • Matsumura, M.1    Nagata, M.2    Nakamura, K.3
  • 115
    • 84895787729 scopus 로고    scopus 로고
    • Zinc oxide nanoparticles provide an adjuvant effect to ovalbumin via a Th2 response in Balb/c mice
    • Roy R, Kumar S, Verma AK, et al. Zinc oxide nanoparticles provide an adjuvant effect to ovalbumin via a Th2 response in Balb/c mice. Int Immunol. 2014;26(3):159–172.
    • (2014) Int Immunol , vol.26 , Issue.3 , pp. 159-172
    • Roy, R.1    Kumar, S.2    Verma, A.K.3
  • 116
    • 84895436939 scopus 로고    scopus 로고
    • Nanotoxicity overview: Nano-threat to susceptible populations
    • Li Y, Zhang Y, Yan B. Nanotoxicity overview: nano-threat to susceptible populations. Int J Mol Sci. 2014;15(3):3671–3697.
    • (2014) Int J Mol Sci , vol.15 , Issue.3 , pp. 3671-3697
    • Li, Y.1    Zhang, Y.2    Yan, B.3
  • 117
    • 84898403565 scopus 로고    scopus 로고
    • Impact of silver nanoparticles and silver ions on innate immune cells
    • Haase H, Fahmi A, Mahltig B. Impact of silver nanoparticles and silver ions on innate immune cells. J Biomed Nanotechnol. 2014;10(6): 1146–1156.
    • (2014) J Biomed Nanotechnol , vol.10 , Issue.6 , pp. 1146-1156
    • Haase, H.1    Fahmi, A.2    Mahltig, B.3
  • 118
    • 84872527864 scopus 로고    scopus 로고
    • Immunomodulatory properties of multi-walled carbon nanotubes in peripheral blood mononuclear cells from healthy subjects and allergic patients
    • Laverny G, Casset A, Purohit A, et al. Immunomodulatory properties of multi-walled carbon nanotubes in peripheral blood mononuclear cells from healthy subjects and allergic patients. Toxicol Lett. 2013; 217(2):91–101.
    • (2013) Toxicol Lett , vol.217 , Issue.2 , pp. 91-101
    • Laverny, G.1    Casset, A.2    Purohit, A.3
  • 119
    • 80052088858 scopus 로고    scopus 로고
    • Activation of the inflammasome by amorphous silica and TiO2 nanoparticles in murine dendritic cells
    • Winter M, Beer HD, Hornung V, Krämer U, Schins RP, Förster I. Activation of the inflammasome by amorphous silica and TiO2 nanoparticles in murine dendritic cells. Nanotoxicology. 2011;5(3):326–340.
    • (2011) Nanotoxicology , vol.5 , Issue.3 , pp. 326-340
    • Winter, M.1    Beer, H.D.2    Hornung, V.3    Krämer, U.4    Schins, R.P.5    Förster, I.6
  • 120
    • 84930505948 scopus 로고    scopus 로고
    • Immunotoxicity of zinc oxide nanoparticles with different size and electrostatic charge
    • Kim CS, Nguyen HD, Ignacio RM, et al. Immunotoxicity of zinc oxide nanoparticles with different size and electrostatic charge. Int J Nanomedicine. 2014;9 Suppl 2:195–205.
    • (2014) Int J Nanomedicine , vol.9 , pp. 195-205
    • Kim, C.S.1    Nguyen, H.D.2    Ignacio, R.M.3
  • 121
    • 84863737713 scopus 로고    scopus 로고
    • Clear and present danger? Engineered nanoparticles and the immune system
    • Fadeel B. Clear and present danger? Engineered nanoparticles and the immune system. Swiss Med Wkly. 2012;142:w13609.
    • (2012) Swiss Med Wkly , vol.142
    • Fadeel, B.1
  • 122
    • 84887867927 scopus 로고    scopus 로고
    • Translational studies of phenotypic probes for the mononuclear phagocyte system and liposomal pharmacology
    • Caron WP, Lay JC, Fong AM, et al. Translational studies of phenotypic probes for the mononuclear phagocyte system and liposomal pharmacology. J Pharmacol Exp Ther. 2013;347(3):599–606.
    • (2013) J Pharmacol Exp Ther , vol.347 , Issue.3 , pp. 599-606
    • Caron, W.P.1    Lay, J.C.2    Fong, A.M.3
  • 123
    • 84859247263 scopus 로고    scopus 로고
    • Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
    • Zhang XD, Wu D, Shen X, et al. Size-dependent in vivo toxicity of PEG-coated gold nanoparticles. Int J Nanomedicine. 2011;6: 2071–2081.
    • (2011) Int J Nanomedicine , vol.6 , pp. 2071-2081
    • Zhang, X.D.1    Wu, D.2    Shen, X.3
  • 124
    • 84930506700 scopus 로고    scopus 로고
    • Active Targeting
    • In: Uchegbu I, Schätzlein A, Cheng W, Lalatsa A, editors, Springer: New York
    • Remedios Serrano Lopez, D, Lalatsa A. Active Targeting. In: Uchegbu I, Schätzlein A, Cheng W, Lalatsa A, editors. Fundamentals of Pharmaceutical Nanoscience. Springer: New York; 2013:337–374.
    • (2013) Fundamentals of Pharmaceutical Nanoscience , pp. 337-374
    • Remedios Serrano Lopez, D.1    Lalatsa, A.2
  • 125
    • 85017820465 scopus 로고    scopus 로고
    • OECD Environment, Health and Safety Publications. [webpage on the Internet]. Guidance on sample preparation and dosimetry for the safety testing of manufactured nanomaterials. Paris, France: Paris Environment Directorate organisation for economic co-operation and development; 2012. Available from, Acessed January 1
    • OECD Environment, Health and Safety Publications. [webpage on the Internet]. Guidance on sample preparation and dosimetry for the safety testing of manufactured nanomaterials. Paris, France: Paris Environment Directorate organisation for economic co-operation and development; 2012. Available from: http://www.oecd.org/officialdocuments/publicdisplaydocumentpdf/?cote=ENV/JM/MONO%282012%2940&docLanguage=En. Acessed January 1, 2015.
    • (2015)
  • 127
    • 0036009467 scopus 로고    scopus 로고
    • Lung macrophage-epithelial cell interactions amplify particle-mediated cytokine release
    • Tao F, Kobzik L. Lung macrophage-epithelial cell interactions amplify particle-mediated cytokine release. Am J Respir Cell Mol Biol. 2002; 26(4):499–505.
    • (2002) Am J Respir Cell Mol Biol , vol.26 , Issue.4 , pp. 499-505
    • Tao, F.1    Kobzik, L.2
  • 128
    • 51049108389 scopus 로고    scopus 로고
    • Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution
    • Dobrovolskaia MA, Aggarwal P, Hall JB, McNeil SE. Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution. Mol Pharm. 2008;5(4):487–495.
    • (2008) Mol Pharm , vol.5 , Issue.4 , pp. 487-495
    • Dobrovolskaia, M.A.1    Aggarwal, P.2    Hall, J.B.3    McNeil, S.E.4
  • 132
    • 77951525639 scopus 로고    scopus 로고
    • Arnida. Cellular uptake and toxicity of gold nanoparticles in prostate cancer cells: A comparative study of rods and spheres
    • Malugin A, Ghandehari H; Arnida. Cellular uptake and toxicity of gold nanoparticles in prostate cancer cells: a comparative study of rods and spheres. J Appl Toxicol. 2010;30(3):212–217.
    • (2010) J Appl Toxicol , vol.30 , Issue.3 , pp. 212-217
    • Malugin, A.1    Ghandehari, H.2
  • 133
    • 53649092909 scopus 로고    scopus 로고
    • The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line
    • Clift MJ, Rothen-Rutishauser B, Brown DM, et al. The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line. Toxicol Appl Pharmacol. 2008;232(3):418–427.
    • (2008) Toxicol Appl Pharmacol , vol.232 , Issue.3 , pp. 418-427
    • Clift, M.J.1    Rothen-Rutishauser, B.2    Brown, D.M.3
  • 134
    • 79952107710 scopus 로고    scopus 로고
    • Cytotoxicity and oxidative stress induced by different metallic nanoparticles on human kidney cells
    • Pujalté I, Passagne I, Brouillaud B, et al. Cytotoxicity and oxidative stress induced by different metallic nanoparticles on human kidney cells. Part Fibre Toxicol. 2011;8:10.
    • (2011) Part Fibre Toxicol , vol.8 , pp. 10
    • Pujalté, I.1    Passagne, I.2    Brouillaud, B.3
  • 135
    • 84866019700 scopus 로고    scopus 로고
    • Interference of engineered nanoparticles with in vitro toxicity assays
    • Kroll A, Pillukat MH, Hahn D, Schnekenburger J. Interference of engineered nanoparticles with in vitro toxicity assays. Arch Toxicol. 2012;86(7):1123–1136.
    • (2012) Arch Toxicol , vol.86 , Issue.7 , pp. 1123-1136
    • Kroll, A.1    Pillukat, M.H.2    Hahn, D.3    Schnekenburger, J.4
  • 136
    • 34047101423 scopus 로고    scopus 로고
    • Biological interactions of functionalized single-wall carbon nanotubes in human epidermal keratinocytes
    • Zhang LW, Zeng L, Barron AR, Monteiro-Riviere NA. Biological interactions of functionalized single-wall carbon nanotubes in human epidermal keratinocytes. Int J Toxicol. 2007;26(2):103–113.
    • (2007) Int J Toxicol , vol.26 , Issue.2 , pp. 103-113
    • Zhang, L.W.1    Zeng, L.2    Barron, A.R.3    Monteiro-Riviere, N.A.4
  • 137
    • 77955927833 scopus 로고    scopus 로고
    • In vitro evaluation of the cytotoxicity of iron oxide nanoparticles with different coatings and different sizes in A3 human T lymphocytes
    • Ying E, Hwang HM. In vitro evaluation of the cytotoxicity of iron oxide nanoparticles with different coatings and different sizes in A3 human T lymphocytes. Sci Total Environ. 2010;408(20):4475–4481.
    • (2010) Sci Total Environ , vol.408 , Issue.20 , pp. 4475-4481
    • Ying, E.1    Hwang, H.M.2
  • 138
    • 27944489615 scopus 로고    scopus 로고
    • In vitro cytotoxicity of nanoparticles in mammalian germline stem cells
    • Braydich-Stolle L, Hussain S, Schlager JJ, Hofmann MC. In vitro cytotoxicity of nanoparticles in mammalian germline stem cells. Toxicol Sci. 2005;88(2):412–419.
    • (2005) Toxicol Sci , vol.88 , Issue.2 , pp. 412-419
    • Braydich-Stolle, L.1    Hussain, S.2    Schlager, J.J.3    Hofmann, M.C.4
  • 139
    • 57349092512 scopus 로고    scopus 로고
    • Novel luminescence assay offers new possibilities for the risk assessment of silica nanoparticles
    • Wahl B, Wahl B, Daum N, Ohrem HL, Lehr CM. Novel luminescence assay offers new possibilities for the risk assessment of silica nanoparticles. Nanotoxicology. 2008;2(4):243–251.
    • (2008) Nanotoxicology , vol.2 , Issue.4 , pp. 243-251
    • Wahl, B.1    Wahl, B.2    Daum, N.3    Ohrem, H.L.4    Lehr, C.M.5
  • 140
    • 38149135806 scopus 로고    scopus 로고
    • Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique
    • Murdock RC, Braydich-Stolle L, Schrand AM, Schlager JJ, Hussain SM. Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique. Toxicol Sci. 2008;101(2):239–253.
    • (2008) Toxicol Sci , vol.101 , Issue.2 , pp. 239-253
    • Murdock, R.C.1    Braydich-Stolle, L.2    Schrand, A.M.3    Schlager, J.J.4    Hussain, S.M.5
  • 141
    • 32044468707 scopus 로고    scopus 로고
    • Challenges for assessing carbon nanomaterial toxicity to the skin
    • Monteiro-Riviere NA, Inman AO. Challenges for assessing carbon nanomaterial toxicity to the skin. Carbon. 2006;44(6):1070–1078.
    • (2006) Carbon , vol.44 , Issue.6 , pp. 1070-1078
    • Monteiro-Riviere, N.A.1    Inman, A.O.2
  • 142
    • 77951545351 scopus 로고    scopus 로고
    • Interactions of aluminum nanoparticles with human epidermal keratinocytes
    • Monteiro-Riviere NA, Oldenburg SJ, Inman AO. Interactions of aluminum nanoparticles with human epidermal keratinocytes. J Appl Toxicol. 2010;30(3):276–285.
    • (2010) J Appl Toxicol , vol.30 , Issue.3 , pp. 276-285
    • Monteiro-Riviere, N.A.1    Oldenburg, S.J.2    Inman, A.O.3
  • 143
    • 33745741441 scopus 로고    scopus 로고
    • Oops they did it again! Carbon nanotubes hoax scientists in viability assays
    • Wörle-Knirsch JM, Pulskamp K, Krug HF. Oops they did it again! Carbon nanotubes hoax scientists in viability assays. Nano Lett. 2006;6(6):1261–1268.
    • (2006) Nano Lett , vol.6 , Issue.6 , pp. 1261-1268
    • Wörle-Knirsch, J.M.1    Pulskamp, K.2    Krug, H.F.3
  • 144
    • 78349249461 scopus 로고    scopus 로고
    • Cytotoxicity of iron oxide nanoparticles made from the thermal decomposition of organometallics and aqueous phase transfer with Pluronic F127
    • Gonzales M, Mitsumori LM, Kushleika JV, Rosenfeld ME, Krishnan KM. Cytotoxicity of iron oxide nanoparticles made from the thermal decomposition of organometallics and aqueous phase transfer with Pluronic F127. Contrast Media Mol Imaging. 2010;5(5):286–293.
    • (2010) Contrast Media Mol Imaging , vol.5 , Issue.5 , pp. 286-293
    • Gonzales, M.1    Mitsumori, L.M.2    Kushleika, J.V.3    Rosenfeld, M.E.4    Krishnan, K.M.5
  • 145
    • 34249691793 scopus 로고    scopus 로고
    • Spectroscopic analysis confirms the interactions between single walled carbon nanotubes and various dyes commonly used to assess cytotoxicity
    • Casey A, Herzog E, Davoren M, Lyng FM, Byrne HJ, Chambers G. Spectroscopic analysis confirms the interactions between single walled carbon nanotubes and various dyes commonly used to assess cytotoxicity. Carbon. 2007;45(7):1425–1432.
    • (2007) Carbon , vol.45 , Issue.7 , pp. 1425-1432
    • Casey, A.1    Herzog, E.2    Davoren, M.3    Lyng, F.M.4    Byrne, H.J.5    Chambers, G.6
  • 146
    • 33947355750 scopus 로고    scopus 로고
    • In vitro toxicity evaluation of single walled carbon nanotubes on human A549 lung cells
    • Davoren M, Herzog E, Casey A, et al. In vitro toxicity evaluation of single walled carbon nanotubes on human A549 lung cells. Toxicol In Vitro. 2007;21(3):438–448.
    • (2007) Toxicol in Vitro , vol.21 , Issue.3 , pp. 438-448
    • Davoren, M.1    Herzog, E.2    Casey, A.3
  • 147
    • 58249141684 scopus 로고    scopus 로고
    • In vitro effects of nanoparticles on renal cells
    • L’azou B, Jorly J, On D, et al. In vitro effects of nanoparticles on renal cells. Part Fibre Toxicol. 2008;5:22.
    • (2008) Part Fibre Toxicol , vol.5 , pp. 22
    • L’Azou, B.1    Jorly, J.2    On, D.3
  • 148
    • 33646857934 scopus 로고    scopus 로고
    • Evaluation of mammalian cell adhesion on surface-modified porous silicon
    • Low SP, Williams KA, Canham LT, Voelcker NH. Evaluation of mammalian cell adhesion on surface-modified porous silicon. Biomaterials. 2006;27(26):4538–4546.
    • (2006) Biomaterials , vol.27 , Issue.26 , pp. 4538-4546
    • Low, S.P.1    Williams, K.A.2    Canham, L.T.3    Voelcker, N.H.4
  • 149
    • 79960698825 scopus 로고    scopus 로고
    • Validation of an LDH assay for assessing nanoparticle toxicity
    • Han X, Gelein R, Corson N, et al. Validation of an LDH assay for assessing nanoparticle toxicity. Toxicology. 2011;287(1–3):99–104.
    • (2011) Toxicology , vol.287 , Issue.13 , pp. 99-104
    • Han, X.1    Gelein, R.2    Corson, N.3
  • 150
    • 84893655513 scopus 로고    scopus 로고
    • Incompatibility of silver nanoparticles with lactate dehydrogenase leakage assay for cellular viability test is attributed to protein binding and reactive oxygen species generation
    • Oh SJ, Kim H, Liu Y, et al. Incompatibility of silver nanoparticles with lactate dehydrogenase leakage assay for cellular viability test is attributed to protein binding and reactive oxygen species generation. Toxicol Lett. 2014;225(3):422–432.
    • (2014) Toxicol Lett , vol.225 , Issue.3 , pp. 422-432
    • Oh, S.J.1    Kim, H.2    Liu, Y.3
  • 151
    • 84897493675 scopus 로고    scopus 로고
    • Understanding interactions of functionalized nanoparticles with proteins: A case study on lactate dehydrogenase
    • Stueker O, Ortega VA, Goss GG, Stepanova M. Understanding interactions of functionalized nanoparticles with proteins: a case study on lactate dehydrogenase. Small. 2014;10(10):2006–2021.
    • (2014) Small , vol.10 , Issue.10 , pp. 2006-2021
    • Stueker, O.1    Ortega, V.A.2    Goss, G.G.3    Stepanova, M.4
  • 152
  • 153
    • 3242792640 scopus 로고    scopus 로고
    • In vivo cytokine secretion and NF-kappaB activation around titanium and copper implants
    • Suska F, Gretzer C, Esposito M, et al. In vivo cytokine secretion and NF-kappaB activation around titanium and copper implants. Biomaterials. 2005;26(5):519–527.
    • (2005) Biomaterials , vol.26 , Issue.5 , pp. 519-527
    • Suska, F.1    Gretzer, C.2    Esposito, M.3
  • 154
    • 35348866826 scopus 로고    scopus 로고
    • The reliability and limits of the MTT reduction assay for carbon nanotubes–cell interaction
    • Belyanskaya L, Manser P, Spohn P, Bruinink A, Wick P. The reliability and limits of the MTT reduction assay for carbon nanotubes–cell interaction. Carbon. 2007;45(13):2643–2648.
    • (2007) Carbon , vol.45 , Issue.13 , pp. 2643-2648
    • Belyanskaya, L.1    Manser, P.2    Spohn, P.3    Bruinink, A.4    Wick, P.5
  • 155
    • 38149032630 scopus 로고    scopus 로고
    • Failure of MTT as a toxicity testing agent for mesoporous silicon microparticles
    • Laaksonen T, Santos H, Vihola H, et al. Failure of MTT as a toxicity testing agent for mesoporous silicon microparticles. Chem Res Toxicol. 2007;20(12):1913–1918.
    • (2007) Chem Res Toxicol , vol.20 , Issue.12 , pp. 1913-1918
    • Laaksonen, T.1    Santos, H.2    Vihola, H.3
  • 156
    • 77951777300 scopus 로고    scopus 로고
    • Interaction between nanoparticles and cytokine proteins: Impact on protein and particle functionality
    • Brown DM, Dickson C, Duncan P, Al-Attili F, Stone V. Interaction between nanoparticles and cytokine proteins: impact on protein and particle functionality. Nanotechnology. 2010;21(21):215104.
    • (2010) Nanotechnology , vol.21 , Issue.21 , pp. 215104
    • Brown, D.M.1    Dickson, C.2    Duncan, P.3    Al-Attili, F.4    Stone, V.5
  • 157
    • 37549010793 scopus 로고    scopus 로고
    • Differential binding of cytokines to environmentally relevant particles: A possible source for misinterpretation of in vitro results?
    • Kocbach A, Totlandsdal AI, Låg M, Refsnes M, Schwarze PE. Differential binding of cytokines to environmentally relevant particles: a possible source for misinterpretation of in vitro results? Toxicol Lett. 2008;176(2):131–137.
    • (2008) Toxicol Lett , vol.176 , Issue.2 , pp. 131-137
    • Kocbach, A.1    Totlandsdal, A.I.2    Låg, M.3    Refsnes, M.4    Schwarze, P.E.5
  • 158
    • 70350666201 scopus 로고    scopus 로고
    • Carbon black and titanium dioxide nanoparticles induce pro-inflammatory responses in bronchial epithelial cells: Need for multiparametric evaluation due to adsorption artifacts
    • Val S, Hussain S, Boland S, Hamel R, Baeza-Squiban A, Marano F. Carbon black and titanium dioxide nanoparticles induce pro-inflammatory responses in bronchial epithelial cells: need for multiparametric evaluation due to adsorption artifacts. Inhal Toxicol. 2009;21 Suppl 1:115–122.
    • Inhal Toxicol. 2009;21 Suppl , vol.1 , pp. 115-122
    • Val, S.1    Hussain, S.2    Boland, S.3    Hamel, R.4    Baeza-Squiban, A.5    Marano, F.6
  • 159
    • 33947413465 scopus 로고    scopus 로고
    • Cytokine responses of human lung cells (BEAS-2B) treated with micron-sized and nanoparticles of metal oxides compared to soil dusts
    • Veranth JM, Kaser EG, Veranth MM, Koch M, Yost GS. Cytokine responses of human lung cells (BEAS-2B) treated with micron-sized and nanoparticles of metal oxides compared to soil dusts. Part Fibre Toxicol. 2007;4:2.
    • (2007) Part Fibre Toxicol , vol.4 , pp. 2
    • Veranth, J.M.1    Kaser, E.G.2    Veranth, M.M.3    Koch, M.4    Yost, G.S.5
  • 160
    • 67449108219 scopus 로고    scopus 로고
    • Comparison of organic and inorganic germanium compounds in cellular radiosensitivity and preparation of germanium nanoparticles as a radiosensitizer
    • Lin MH, Hsu TS, Yang PM, Tsai MY, Perng TP, Lin LY. Comparison of organic and inorganic germanium compounds in cellular radiosensitivity and preparation of germanium nanoparticles as a radiosensitizer. Int J Radiat Biol. 2009;85(3):214–226.
    • (2009) Int J Radiat Biol , vol.85 , Issue.3 , pp. 214-226
    • Lin, M.H.1    Hsu, T.S.2    Yang, P.M.3    Tsai, M.Y.4    Perng, T.P.5    Lin, L.Y.6
  • 161
    • 34250826138 scopus 로고    scopus 로고
    • Carbon black particles increase reactive oxygen species formation in rat alveolar macrophages in vitro
    • Aam BB, Fonnum F. Carbon black particles increase reactive oxygen species formation in rat alveolar macrophages in vitro. Arch Toxicol. 2007;81(6):441–446.
    • (2007) Arch Toxicol , vol.81 , Issue.6 , pp. 441-446
    • Aam, B.B.1    Fonnum, F.2
  • 162
    • 84873461682 scopus 로고    scopus 로고
    • Intracellular oxidative stress caused by nanoparticles: What do we measure with the dichlorofluorescein assay?
    • Hoet PH, Nemery B, Napierska D. Intracellular oxidative stress caused by nanoparticles: what do we measure with the dichlorofluorescein assay? Nano Today. 2013;8(3):223–227.
    • (2013) Nano Today , vol.8 , Issue.3 , pp. 223-227
    • Hoet, P.H.1    Nemery, B.2    Napierska, D.3
  • 163
    • 77957871283 scopus 로고    scopus 로고
    • The comet assay in nanotoxicology research
    • Karlsson HL. The comet assay in nanotoxicology research. Anal Bioanal Chem. 2010;398(2):651–666.
    • (2010) Anal Bioanal Chem , vol.398 , Issue.2 , pp. 651-666
    • Karlsson, H.L.1
  • 165
    • 0034597567 scopus 로고    scopus 로고
    • Adjuvant activity of particulate pollutants in different mouse models
    • van Zijverden M, Granum B. Adjuvant activity of particulate pollutants in different mouse models. Toxicology. 2000;152(1–3):69–77.
    • (2000) Toxicology , vol.152 , Issue.13 , pp. 69-77
    • Van Zijverden, M.1    Granum, B.2
  • 166
    • 4344697146 scopus 로고    scopus 로고
    • Size-dependent immunogenicity: Therapeutic and protective properties of nano-vaccines against tumors
    • Fifis T, Gamvrellis A, Crimeen-Irwin B, et al. Size-dependent immunogenicity: therapeutic and protective properties of nano-vaccines against tumors. J Immunol. 2004;173(5):3148–3154.
    • (2004) J Immunol , vol.173 , Issue.5 , pp. 3148-3154
    • Fifis, T.1    Gamvrellis, A.2    Crimeen-Irwin, B.3
  • 167
    • 10044282922 scopus 로고    scopus 로고
    • The capacity of particles to increase allergic sensitization is predicted by particle number and surface area, not by particle mass
    • Nygaard UC, Samuelsen M, Aase A, Løvik M. The capacity of particles to increase allergic sensitization is predicted by particle number and surface area, not by particle mass. Toxicol Sci. 2004;82(2):515–524.
    • (2004) Toxicol Sci , vol.82 , Issue.2 , pp. 515-524
    • Nygaard, U.C.1    Samuelsen, M.2    Aase, A.3    Løvik, M.4
  • 168
    • 10044259889 scopus 로고    scopus 로고
    • The IgE adjuvant effect of particles: Characterisation of the primary cellular response in the draining lymph node
    • Nygaard UC, Ormstad H, Aase A, Løvik M. The IgE adjuvant effect of particles: characterisation of the primary cellular response in the draining lymph node. Toxicology. 2005;206(2):181–193.
    • (2005) Toxicology , vol.206 , Issue.2 , pp. 181-193
    • Nygaard, U.C.1    Ormstad, H.2    Aase, A.3    Løvik, M.4
  • 170
    • 42949092649 scopus 로고    scopus 로고
    • Sequential exposure to carbon nanotubes and bacteria enhances pulmonary inflammation and infectivity
    • Shvedova AA, Fabisiak JP, Kisin ER, et al. Sequential exposure to carbon nanotubes and bacteria enhances pulmonary inflammation and infectivity. Am J Respir Cell Mol Biol. 2008;38(5):579–590.
    • (2008) Am J Respir Cell Mol Biol , vol.38 , Issue.5 , pp. 579-590
    • Shvedova, A.A.1    Fabisiak, J.P.2    Kisin, E.R.3
  • 171
    • 80052699285 scopus 로고    scopus 로고
    • A single intratracheal instillation of single-walled carbon nanotubes induced early lung fibrosis and subchronic tissue damage in mice
    • Park EJ, Roh J, Kim SN, et al. A single intratracheal instillation of single-walled carbon nanotubes induced early lung fibrosis and subchronic tissue damage in mice. Arch Toxicol. 2011;85(9):1121–1131.
    • (2011) Arch Toxicol , vol.85 , Issue.9 , pp. 1121-1131
    • Park, E.J.1    Roh, J.2    Kim, S.N.3
  • 172
    • 77249172273 scopus 로고    scopus 로고
    • Repeated pulmonary exposure to single-walled carbon nanotubes exacerbates allergic inflammation of the airway: Possible role of oxidative stress
    • Inoue K, Yanagisawa R, Koike E, Nishikawa M, Takano H. Repeated pulmonary exposure to single-walled carbon nanotubes exacerbates allergic inflammation of the airway: Possible role of oxidative stress. Free Radic Biol Med. 2010;48(7):924–934.
    • (2010) Free Radic Biol Med , vol.48 , Issue.7 , pp. 924-934
    • Inoue, K.1    Yanagisawa, R.2    Koike, E.3    Nishikawa, M.4    Takano, H.5
  • 173
    • 58749093286 scopus 로고    scopus 로고
    • Effects of pulmonary exposure to carbon nanotubes on lung and systemic inflammation with coagulatory disturbance induced by lipopolysaccharide in mice
    • Inoue K, Takano H, Koike E, et al. Effects of pulmonary exposure to carbon nanotubes on lung and systemic inflammation with coagulatory disturbance induced by lipopolysaccharide in mice. Exp Biol Med (Maywood). 2008;233(12):1583–1590.
    • (2008) Exp Biol Med (Maywood) , vol.233 , Issue.12 , pp. 1583-1590
    • Inoue, K.1    Takano, H.2    Koike, E.3
  • 174
    • 77952882503 scopus 로고    scopus 로고
    • Carbon nanotubes induce inflammation but decrease the production of reactive oxygen species in lung
    • Crouzier D, Follot S, Gentilhomme E, et al. Carbon nanotubes induce inflammation but decrease the production of reactive oxygen species in lung. Toxicology. 2010;272(1–3):39–45.
    • (2010) Toxicology , vol.272 , Issue.13 , pp. 39-45
    • Crouzier, D.1    Follot, S.2    Gentilhomme, E.3
  • 175
    • 80655144973 scopus 로고    scopus 로고
    • Immune responses of BALB/c mice to subcutaneously injected multi-walled carbon nanotubes
    • Meng J, Yang M, Jia F, Xu Z, Kong H, Xu H. Immune responses of BALB/c mice to subcutaneously injected multi-walled carbon nanotubes. Nanotoxicology. 2011;5(4):583–591.
    • (2011) Nanotoxicology , vol.5 , Issue.4 , pp. 583-591
    • Meng, J.1    Yang, M.2    Jia, F.3    Xu, Z.4    Kong, H.5    Xu, H.6
  • 177
    • 79961094494 scopus 로고    scopus 로고
    • Direct effects of carbon nanotubes on dendritic cells induce immune suppression upon pulmonary exposure
    • Tkach AV, Shurin GV, Shurin MR, et al. Direct effects of carbon nanotubes on dendritic cells induce immune suppression upon pulmonary exposure. ACS Nano. 2011;5(7):5755–5762.
    • (2011) ACS Nano , vol.5 , Issue.7 , pp. 5755-5762
    • Tkach, A.V.1    Shurin, G.V.2    Shurin, M.R.3
  • 178
    • 63649132140 scopus 로고    scopus 로고
    • Pro-inflammatory and potential allergic responses resulting from B cell activation in mice treated with multi-walled carbon nanotubes by intratracheal instillation
    • Park EJ, Cho WS, Jeong J, Yi J, Choi K, Park K. Pro-inflammatory and potential allergic responses resulting from B cell activation in mice treated with multi-walled carbon nanotubes by intratracheal instillation. Toxicology. 2009;259(3):113–121.
    • (2009) Toxicology , vol.259 , Issue.3 , pp. 113-121
    • Park, E.J.1    Cho, W.S.2    Jeong, J.3    Yi, J.4    Choi, K.5    Park, K.6
  • 179
    • 84877100531 scopus 로고    scopus 로고
    • Intravenously delivered graphene nanosheets and multiwalled carbon nanotubes induce site-specific Th2 inflammatory responses via the IL-33/ST2 axis
    • Wang X, Podila R, Shannahan JH, Rao AM, Brown JM. Intravenously delivered graphene nanosheets and multiwalled carbon nanotubes induce site-specific Th2 inflammatory responses via the IL-33/ST2 axis. Int J Nanomedicine. 2013;8:1733–1748.
    • (2013) Int J Nanomedicine , vol.8 , pp. 1733-1748
    • Wang, X.1    Podila, R.2    Shannahan, J.H.3    Rao, A.M.4    Brown, J.M.5
  • 180
    • 84856888108 scopus 로고    scopus 로고
    • Effects of sustained stimulation with multi-wall carbon nanotubes on immune and inflammatory responses in mice
    • Yamaguchi A, Fujitani T, Ohyama K, et al. Effects of sustained stimulation with multi-wall carbon nanotubes on immune and inflammatory responses in mice. J Toxicol Sci. 2012;37(1):177–189.
    • (2012) J Toxicol Sci , vol.37 , Issue.1 , pp. 177-189
    • Yamaguchi, A.1    Fujitani, T.2    Ohyama, K.3
  • 181
    • 65749116404 scopus 로고    scopus 로고
    • Effects of multi-walled carbon nanotubes on a murine allergic airway inflammation model
    • Inoue K, Koike E, Yanagisawa R, Hirano S, Nishikawa M, Takano H. Effects of multi-walled carbon nanotubes on a murine allergic airway inflammation model. Toxicol Appl Pharmacol. 2009;237(3): 306–316.
    • (2009) Toxicol Appl Pharmacol , vol.237 , Issue.3 , pp. 306-316
    • Inoue, K.1    Koike, E.2    Yanagisawa, R.3    Hirano, S.4    Nishikawa, M.5    Takano, H.6
  • 183
    • 77955496545 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide enhances PDGF signaling and pulmonary fibrosis in rats exposed to carbon nanotubes
    • Cesta MF, Ryman-Rasmussen JP, Wallace DG, et al. Bacterial lipopolysaccharide enhances PDGF signaling and pulmonary fibrosis in rats exposed to carbon nanotubes. Am J Respir Cell Mol Biol. 2010; 43(2):142–151.
    • (2010) Am J Respir Cell Mol Biol , vol.43 , Issue.2 , pp. 142-151
    • Cesta, M.F.1    Ryman-Rasmussen, J.P.2    Wallace, D.G.3
  • 184
    • 64349090027 scopus 로고    scopus 로고
    • Subchronic inhalation toxicity of silver nanoparticles
    • Sung JH, Ji JH, Park JD, et al. Subchronic inhalation toxicity of silver nanoparticles. Toxicol Sci. 2009;108(2):452–461.
    • (2009) Toxicol Sci , vol.108 , Issue.2 , pp. 452-461
    • Sung, J.H.1    Ji, J.H.2    Park, J.D.3
  • 185
    • 36749097369 scopus 로고    scopus 로고
    • Intracellular GSH levels rather than ROS levels are tightly related to AMA-induced HeLa cell death
    • Han YH, Kim SH, Kim SZ, Park WH. Intracellular GSH levels rather than ROS levels are tightly related to AMA-induced HeLa cell death. Chem Biol Interact. 2008;171(1):67–78.
    • (2008) Chem Biol Interact , vol.171 , Issue.1 , pp. 67-78
    • Han, Y.H.1    Kim, S.H.2    Kim, S.Z.3    Park, W.H.4
  • 186
    • 77955419251 scopus 로고    scopus 로고
    • Repeated-dose toxicity and inflammatory responses in mice by oral administration of silver nanoparticles
    • Park EJ, Bae E, Yi J, et al. Repeated-dose toxicity and inflammatory responses in mice by oral administration of silver nanoparticles. Environ Toxicol Pharmacol. 2010;30(2):162–168.
    • (2010) Environ Toxicol Pharmacol , vol.30 , Issue.2 , pp. 162-168
    • Park, E.J.1    Bae, E.2    Yi, J.3
  • 187
    • 84902296031 scopus 로고    scopus 로고
    • Immunotoxicity of silver nanoparticles in an intravenous 28-day repeated-dose toxicity study in rats
    • Vandebriel RJ, Tonk EC, de la Fonteyne-Blankestijn LJ, et al. Immunotoxicity of silver nanoparticles in an intravenous 28-day repeated-dose toxicity study in rats. Part Fibre Toxicol. 2014;11:21.
    • (2014) Part Fibre Toxicol , vol.11 , pp. 21
    • Vandebriel, R.J.1    Tonk, E.C.2    De La Fonteyne-Blankestijn, L.J.3
  • 188
    • 84881270338 scopus 로고    scopus 로고
    • Taiwan CardioPulmonary Research Group (T-CPR). Comparative proteomics of inhaled silver nanoparticles in healthy and allergen provoked mice
    • Su CL, Chen TT, Chang CC, et al; Taiwan CardioPulmonary Research Group (T-CPR). Comparative proteomics of inhaled silver nanoparticles in healthy and allergen provoked mice. Int J Nanomedicine. 2013;8:2783–2799.
    • (2013) Int J Nanomedicine , vol.8 , pp. 2783-2799
    • Su, C.L.1    Chen, T.T.2    Chang, C.C.3
  • 189
    • 78649577012 scopus 로고    scopus 로고
    • Impact of agglomeration state of nano-and submicron sized gold particles on pulmonary inflammation
    • Gosens I, Post JA, de la Fonteyne LJ, et al. Impact of agglomeration state of nano-and submicron sized gold particles on pulmonary inflammation. Part Fibre Toxicol. 2010;7(1):37.
    • (2010) Part Fibre Toxicol , vol.7 , Issue.1 , pp. 37
    • Gosens, I.1    Post, J.A.2    De La Fonteyne, L.J.3
  • 190
    • 84879349261 scopus 로고    scopus 로고
    • Effects of naked gold nanoparticles on proinflammatory cytokines mRNA expression in rat liver and kidney
    • Khan HA, Abdelhalim MA, Alhomida AS, Al-Ayed MS. Effects of naked gold nanoparticles on proinflammatory cytokines mRNA expression in rat liver and kidney. Biomed Res Int. 2013;2013:590730.
    • (2013) Biomed Res Int , vol.2013 , pp. 590730
    • Khan, H.A.1    Abdelhalim, M.A.2    Alhomida, A.S.3    Al-Ayed, M.S.4
  • 191
    • 79953653520 scopus 로고    scopus 로고
    • Lung exposure to nanoparticles modulates an asthmatic response in a mouse model
    • Hussain S, Vanoirbeek JA, Luyts K, et al. Lung exposure to nanoparticles modulates an asthmatic response in a mouse model. Eur Respir J. 2011;37(2):299–309.
    • (2011) Eur Respir J , vol.37 , Issue.2 , pp. 299-309
    • Hussain, S.1    Vanoirbeek, J.A.2    Luyts, K.3
  • 192
    • 67651001573 scopus 로고    scopus 로고
    • Pulmonary toxicity and kinetic study of Cy5.5-conjugated superparamagnetic iron oxide nanoparticles by optical imaging
    • Cho WS, Cho M, Kim SR, et al. Pulmonary toxicity and kinetic study of Cy5.5-conjugated superparamagnetic iron oxide nanoparticles by optical imaging. Toxicol Appl Pharmacol. 2009;239(1):106–115.
    • (2009) Toxicol Appl Pharmacol , vol.239 , Issue.1 , pp. 106-115
    • Cho, W.S.1    Cho, M.2    Kim, S.R.3
  • 193
    • 77954818793 scopus 로고    scopus 로고
    • Inflammatory responses may be induced by a single intratracheal instillation of iron nanoparticles in mice
    • Park EJ, Kim H, Kim Y, Yi J, Choi K, Park K. Inflammatory responses may be induced by a single intratracheal instillation of iron nanoparticles in mice. Toxicology. 2010;275(1–3):65–71.
    • (2010) Toxicology , vol.275 , Issue.13 , pp. 65-71
    • Park, E.J.1    Kim, H.2    Kim, Y.3    Yi, J.4    Choi, K.5    Park, K.6
  • 194
    • 79952118330 scopus 로고    scopus 로고
    • The effect of magnetic nanoparticles of Fe(3)O(4) on immune function in normal ICR mice
    • Chen BA, Jin N, Wang J, et al. The effect of magnetic nanoparticles of Fe(3)O(4) on immune function in normal ICR mice. Int J Nanomedicine. 2010;5:593–599.
    • (2010) Int J Nanomedicine , vol.5 , pp. 593-599
    • Chen, B.A.1    Jin, N.2    Wang, J.3
  • 195
    • 80155198296 scopus 로고    scopus 로고
    • A single exposure to iron oxide nanoparticles attenuates antigen-specific antibody production and T-cell reactivity in ovalbumin-sensitized BALB/c mice
    • Shen CC, Wang CC, Liao MH, Jan TR. A single exposure to iron oxide nanoparticles attenuates antigen-specific antibody production and T-cell reactivity in ovalbumin-sensitized BALB/c mice. Int J Nanomedicine. 2011;6:1229–1235.
    • (2011) Int J Nanomedicine , vol.6 , pp. 1229-1235
    • Shen, C.C.1    Wang, C.C.2    Liao, M.H.3    Jan, T.R.4
  • 196
    • 84870330660 scopus 로고    scopus 로고
    • Iron oxide nanoparticles suppressed T helper 1 cell-mediated immunity in a murine model of delayed-type hypersensitivity
    • Shen CC, Liang HJ, Wang CC, Liao MH, Jan TR. Iron oxide nanoparticles suppressed T helper 1 cell-mediated immunity in a murine model of delayed-type hypersensitivity. Int J Nanomedicine. 2012;7:2729–2737.
    • (2012) Int J Nanomedicine , vol.7 , pp. 2729-2737
    • Shen, C.C.1    Liang, H.J.2    Wang, C.C.3    Liao, M.H.4    Jan, T.R.5
  • 197
    • 84863012772 scopus 로고    scopus 로고
    • Exosomes as extrapulmonary signaling conveyors for nanoparticle-induced systemic immune activation
    • Zhu M, Li Y, Shi J, Feng W, Nie G, Zhao Y. Exosomes as extrapulmonary signaling conveyors for nanoparticle-induced systemic immune activation. Small. 2012;8(3):404–412.
    • (2012) Small , vol.8 , Issue.3 , pp. 404-412
    • Zhu, M.1    Li, Y.2    Shi, J.3    Feng, W.4    Nie, G.5    Zhao, Y.6
  • 198
    • 84862898405 scopus 로고    scopus 로고
    • Nanoparticle-induced exosomes target antigen-presenting cells to initiate Th1-type immune activation
    • Zhu M, Tian X, Song X, et al. Nanoparticle-induced exosomes target antigen-presenting cells to initiate Th1-type immune activation. Small. 2012;8(18):2841–2848.
    • (2012) Small , vol.8 , Issue.18 , pp. 2841-2848
    • Zhu, M.1    Tian, X.2    Song, X.3
  • 199
    • 84861143559 scopus 로고    scopus 로고
    • Effect of submicron and nano-iron oxide particles on pulmonary immunity in mice
    • Ban M, Langonné I, Huguet N, Goutet M. Effect of submicron and nano-iron oxide particles on pulmonary immunity in mice. Toxicol Lett. 2012;210(3):267–275.
    • (2012) Toxicol Lett , vol.210 , Issue.3 , pp. 267-275
    • Ban, M.1    Langonné, I.2    Huguet, N.3    Goutet, M.4
  • 200
    • 78650269106 scopus 로고    scopus 로고
    • Metal oxide nanoparticles induce unique inflammatory footprints in the lung: Important implications for nanoparticle testing
    • Cho WS, Duffin R, Poland CA, et al. Metal oxide nanoparticles induce unique inflammatory footprints in the lung: important implications for nanoparticle testing. Environ Health Perspect. 2010;118(12):1699–1706.
    • (2010) Environ Health Perspect , vol.118 , Issue.12 , pp. 1699-1706
    • Cho, W.S.1    Duffin, R.2    Poland, C.A.3
  • 201
    • 77955873730 scopus 로고    scopus 로고
    • Cytotoxicity of amorphous silica particles against macrophage-like THP-1 cells depends on particle-size and surface properties
    • Morishige T, Yoshioka Y, Inakura H, et al. Cytotoxicity of amorphous silica particles against macrophage-like THP-1 cells depends on particle-size and surface properties. Pharmazie. 2010;65(8):596–599.
    • (2010) Pharmazie , vol.65 , Issue.8 , pp. 596-599
    • Morishige, T.1    Yoshioka, Y.2    Inakura, H.3
  • 202
    • 84875155427 scopus 로고    scopus 로고
    • Kupffer cell-mediated hepatic injury induced by silica nanoparticles in vitro and in vivo
    • Chen Q, Xue Y, Sun J. Kupffer cell-mediated hepatic injury induced by silica nanoparticles in vitro and in vivo. Int J Nanomedicine. 2013;8: 1129–1140.
    • (2013) Int J Nanomedicine , vol.8 , pp. 1129-1140
    • Chen, Q.1    Xue, Y.2    Sun, J.3
  • 204
    • 84856437765 scopus 로고    scopus 로고
    • Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection
    • Hirai T, Yoshikawa T, Nabeshi H, et al. Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection. Part Fibre Toxicol. 2012;9:3.
    • (2012) Part Fibre Toxicol , vol.9 , pp. 3
    • Hirai, T.1    Yoshikawa, T.2    Nabeshi, H.3
  • 205
    • 79951904474 scopus 로고    scopus 로고
    • Adverse effect of nano-silicon dioxide on lung function of rats with or without ovalbumin immunization
    • Han B, Guo J, Abrahaley T, et al. Adverse effect of nano-silicon dioxide on lung function of rats with or without ovalbumin immunization. PLoS One. 2011;6(2):e17236.
    • (2011) Plos One , vol.6 , Issue.2
    • Han, B.1    Guo, J.2    Abrahaley, T.3
  • 206
    • 84873365984 scopus 로고    scopus 로고
    • Titanium oxide nanoparticle instillation induces inflammation and inhibits lung development in mice
    • Ambalavanan N, Stanishevsky A, Bulger A, et al. Titanium oxide nanoparticle instillation induces inflammation and inhibits lung development in mice. Am J Physiol Lung Cell Mol Physiol. 2013;304(3): L152–L161.
    • (2013) Am J Physiol Lung Cell Mol Physiol , vol.304 , Issue.3 , pp. L152-L161
    • Ambalavanan, N.1    Stanishevsky, A.2    Bulger, A.3
  • 208
    • 0028104529 scopus 로고
    • Correlation between particle size, in vivo particle persistence, and lung injury
    • Oberdörster G, Ferin J, Lehnert BE. Correlation between particle size, in vivo particle persistence, and lung injury. Environ Health Perspect. 1994;102 Suppl 5:173–179.
    • (1994) Environ Health Perspect , vol.102 , pp. 173-179
    • Oberdörster, G.1    Ferin, J.2    Lehnert, B.E.3
  • 209
    • 0034252225 scopus 로고    scopus 로고
    • Acute pulmonary effects of ultrafine particles in rats and mice
    • disc. 75–86
    • Oberdörster G, Finkelstein JN, Johnston C, et al. Acute pulmonary effects of ultrafine particles in rats and mice. Res Rep Health Eff Inst. 2000;(96):5–74; disc. 75–86.
    • (2000) Res Rep Health Eff Inst , Issue.96 , pp. 5-74
    • Oberdörster, G.1    Finkelstein, J.N.2    Johnston, C.3
  • 210
    • 79955657973 scopus 로고    scopus 로고
    • Acute and subchronic airway inflammation after intratracheal instillation of quartz and titanium dioxide agglomerates in mice
    • Roursgaard M, Jensen KA, Poulsen SS, et al. Acute and subchronic airway inflammation after intratracheal instillation of quartz and titanium dioxide agglomerates in mice. Scientific World Journal. 2011;11: 801–825.
    • (2011) Scientific World Journal , vol.11 , pp. 801-825
    • Roursgaard, M.1    Jensen, K.A.2    Poulsen, S.S.3
  • 211
    • 79955634536 scopus 로고    scopus 로고
    • Lung exposure of titanium dioxide nanoparticles induces innate immune activation and long-lasting lymphocyte response in the Dark Agouti rat
    • Gustafsson Å, Lindstedt E, Elfsmark LS, Bucht A. Lung exposure of titanium dioxide nanoparticles induces innate immune activation and long-lasting lymphocyte response in the Dark Agouti rat. J Immunotoxicol. 2011;8(2):111–121.
    • (2011) J Immunotoxicol , vol.8 , Issue.2 , pp. 111-121
    • Gustafsson, Å.1    Lindstedt, E.2    Elfsmark, L.S.3    Bucht, A.4
  • 212
    • 69449107408 scopus 로고    scopus 로고
    • Comparative pulmonary toxicity study of nano-TiO(2) particles of different sizes and agglomerations in rats: Different short-and long-term post-instillation results
    • Kobayashi N, Naya M, Endoh S, Maru J, Yamamoto K, Nakanishi J. Comparative pulmonary toxicity study of nano-TiO(2) particles of different sizes and agglomerations in rats: different short-and long-term post-instillation results. Toxicology. 2009;264(1–2):110–118.
    • (2009) Toxicology , vol.264 , Issue.12 , pp. 110-118
    • Kobayashi, N.1    Naya, M.2    Endoh, S.3    Maru, J.4    Yamamoto, K.5    Nakanishi, J.6
  • 213
    • 84902958103 scopus 로고    scopus 로고
    • Nano-sized titanium dioxide-induced splenic toxicity: A biological pathway explored using microarray technology
    • Sheng L, Wang L, Sang X, et al. Nano-sized titanium dioxide-induced splenic toxicity: a biological pathway explored using microarray technology. J Hazard Mater. 2014;278:180–188.
    • (2014) J Hazard Mater , vol.278 , pp. 180-188
    • Sheng, L.1    Wang, L.2    Sang, X.3
  • 214
    • 84906783859 scopus 로고    scopus 로고
    • Immunomodulatory effects in the spleen-injured mice following exposure to titanium dioxide nanoparticles
    • Sang X, Fei M, Sheng L, et al. Immunomodulatory effects in the spleen-injured mice following exposure to titanium dioxide nanoparticles. J Biomed Mater Res A. 2014;102(10):3562–3572.
    • (2014) J Biomed Mater Res A , vol.102 , Issue.10 , pp. 3562-3572
    • Sang, X.1    Fei, M.2    Sheng, L.3
  • 215
    • 70350589283 scopus 로고    scopus 로고
    • The acute liver injury in mice Caused by nano-anatase TiO2
    • Ma L, Zhao J, Wang J, et al. The acute liver injury in mice Caused by nano-anatase TiO2. Nanoscale Res Lett. 2009;4(11):1275–1285.
    • (2009) Nanoscale Res Lett , vol.4 , Issue.11 , pp. 1275-1285
    • Ma, L.1    Zhao, J.2    Wang, J.3
  • 216
    • 74549186977 scopus 로고    scopus 로고
    • Nano titanium dioxide particles promote allergic sensitization and lung inflammation in mice
    • Larsen ST, Roursgaard M, Jensen KA, Nielsen GD. Nano titanium dioxide particles promote allergic sensitization and lung inflammation in mice. Basic Clin Pharmacol Toxicol. 2010;106(2):114–117.
    • (2010) Basic Clin Pharmacol Toxicol , vol.106 , Issue.2 , pp. 114-117
    • Larsen, S.T.1    Roursgaard, M.2    Jensen, K.A.3    Nielsen, G.D.4
  • 217
    • 33750567127 scopus 로고    scopus 로고
    • Ultrafine but not fine particulate matter causes airway inflammation and allergic airway sensitization to co-administered antigen in mice
    • de Haar C, Hassing I, Bol M, Bleumink R, Pieters R. Ultrafine but not fine particulate matter causes airway inflammation and allergic airway sensitization to co-administered antigen in mice. Clin Exp Allergy. 2006;36(11):1469–1479.
    • (2006) Clin Exp Allergy , vol.36 , Issue.11 , pp. 1469-1479
    • De Haar, C.1    Hassing, I.2    Bol, M.3    Bleumink, R.4    Pieters, R.5
  • 218
    • 77149158798 scopus 로고    scopus 로고
    • Pulmonary inflammation after intraperitoneal administration of ultrafine titanium dioxide (TiO2) at rest or in lungs primed with lipopolysaccharide
    • Moon C, Park HJ, Choi YH, Park EM, Castranova V, Kang JL. Pulmonary inflammation after intraperitoneal administration of ultrafine titanium dioxide (TiO2) at rest or in lungs primed with lipopolysaccharide. J Toxicol Environ Health A. 2010;73(5):396–409.
    • (2010) J Toxicol Environ Health A , vol.73 , Issue.5 , pp. 396-409
    • Moon, C.1    Park, H.J.2    Choi, Y.H.3    Park, E.M.4    Castranova, V.5    Kang, J.L.6
  • 219
    • 84899046918 scopus 로고    scopus 로고
    • Toxicity assessment of zinc oxide nanoparticles using sub-acute and sub-chronic murine inhalation models
    • Adamcakova-Dodd A, Stebounova LV, Kim JS, et al. Toxicity assessment of zinc oxide nanoparticles using sub-acute and sub-chronic murine inhalation models. Part Fibre Toxicol. 2014;11:15.
    • (2014) Part Fibre Toxicol , vol.11 , pp. 15
    • Adamcakova-Dodd, A.1    Stebounova, L.V.2    Kim, J.S.3
  • 220
    • 84878457573 scopus 로고    scopus 로고
    • Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: The NIEHS Nano GO Consortium
    • Xia T, Hamilton RF, Bonner JC, et al. Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium. Environ Health Perspect. 2013;121(6):683–690.
    • (2013) Environ Health Perspect , vol.121 , Issue.6 , pp. 683-690
    • Xia, T.1    Hamilton, R.F.2    Bonner, J.C.3
  • 221
    • 70350690489 scopus 로고    scopus 로고
    • Single-walled carbon nanotubes impair human macrophage engulfment of apoptotic cell corpses
    • Witasp E, Shvedova AA, Kagan VE, Fadeel B. Single-walled carbon nanotubes impair human macrophage engulfment of apoptotic cell corpses. Inhal Toxicol. 2009;21 Suppl 1:131–136.
    • (2009) Inhal Toxicol , vol.21 , pp. 131-136
    • Witasp, E.1    Shvedova, A.A.2    Kagan, V.E.3    Fadeel, B.4
  • 222
    • 67749088047 scopus 로고    scopus 로고
    • Studies on the biocompatibility and the interaction of silver nanoparticles with human mesenchymal stem cells (HMSCs)
    • Greulich C, Kittler S, Epple M, Muhr G, Köller M. Studies on the biocompatibility and the interaction of silver nanoparticles with human mesenchymal stem cells (hMSCs). Langenbecks Arch Surg. 2009;394(3):495–502.
    • (2009) Langenbecks Arch Surg , vol.394 , Issue.3 , pp. 495-502
    • Greulich, C.1    Kittler, S.2    Epple, M.3    Muhr, G.4    Köller, M.5
  • 223
    • 35748933519 scopus 로고    scopus 로고
    • The effects of nano-silver on the proliferation and cytokine expression by peripheral blood mononuclear cells
    • Shin SH, Ye MK, Kim HS, Kang HS. The effects of nano-silver on the proliferation and cytokine expression by peripheral blood mononuclear cells. Int Immunopharmacol. 2007;7(13):1813–1818.
    • (2007) Int Immunopharmacol , vol.7 , Issue.13 , pp. 1813-1818
    • Shin, S.H.1    Ye, M.K.2    Kim, H.S.3    Kang, H.S.4
  • 224
    • 55949113520 scopus 로고    scopus 로고
    • Unique cellular interaction of silver nanoparticles: Size-dependent generation of reactive oxygen species
    • Carlson C, Hussain SM, Schrand AM, et al. Unique cellular interaction of silver nanoparticles: size-dependent generation of reactive oxygen species. J Phys Chem B. 2008;112(43):13608–13619.
    • (2008) J Phys Chem B , vol.112 , Issue.43 , pp. 13608-13619
    • Carlson, C.1    Hussain, S.M.2    Schrand, A.M.3
  • 225
    • 78951469265 scopus 로고    scopus 로고
    • Nanosilver induces minimal lung toxicity or inflammation in a subacute murine inhalation model
    • Stebounova LV, Adamcakova-Dodd A, Kim JS, et al. Nanosilver induces minimal lung toxicity or inflammation in a subacute murine inhalation model. Part Fibre Toxicol. 2011;8(1):5.
    • (2011) Part Fibre Toxicol , vol.8 , Issue.1 , pp. 5
    • Stebounova, L.V.1    Adamcakova-Dodd, A.2    Kim, J.S.3
  • 226
    • 84913613623 scopus 로고    scopus 로고
    • Toxicity of nanoparticles embedded in paints compared with pristine nanoparticles in mice
    • Smulders S, Luyts K, Brabants G, et al. Toxicity of nanoparticles embedded in paints compared with pristine nanoparticles in mice. Toxicol Sci. 2014;141(1):132–140.
    • (2014) Toxicol Sci , vol.141 , Issue.1 , pp. 132-140
    • Smulders, S.1    Luyts, K.2    Brabants, G.3
  • 227
    • 84863990988 scopus 로고    scopus 로고
    • Inflammasome formation and IL-1β release by human blood monocytes in response to silver nanoparticles
    • Yang EJ, Kim S, Kim JS, Choi IH. Inflammasome formation and IL-1β release by human blood monocytes in response to silver nanoparticles. Biomaterials. 2012;33(28):6858–6867.
    • (2012) Biomaterials , vol.33 , Issue.28 , pp. 6858-6867
    • Yang, E.J.1    Kim, S.2    Kim, J.S.3    Choi, I.H.4
  • 228
    • 79551594933 scopus 로고    scopus 로고
    • In vitro toxicity of silver nanoparticles on murine peritoneal macrophages
    • Shavandi Z, Ghazanfari T, Moghaddam KN. In vitro toxicity of silver nanoparticles on murine peritoneal macrophages. Immunopharmacol Immunotoxicol. 2011;33(1):135–140.
    • (2011) Immunopharmacol Immunotoxicol , vol.33 , Issue.1 , pp. 135-140
    • Shavandi, Z.1    Ghazanfari, T.2    Moghaddam, K.N.3
  • 229
    • 77952932220 scopus 로고    scopus 로고
    • Microglial response to gold nanoparticles
    • Hutter E, Boridy S, Labrecque S, et al. Microglial response to gold nanoparticles. ACS Nano. 2010;4(5):2595–2606.
    • (2010) ACS Nano , vol.4 , Issue.5 , pp. 2595-2606
    • Hutter, E.1    Boridy, S.2    Labrecque, S.3
  • 230
    • 67749137301 scopus 로고    scopus 로고
    • Cytotoxicity and immunological response of gold and silver nanoparticles of different sizes
    • Yen HJ, Hsu SH, Tsai CL. Cytotoxicity and immunological response of gold and silver nanoparticles of different sizes. Small. 2009;5(13): 1553–1561.
    • (2009) Small , vol.5 , Issue.13 , pp. 1553-1561
    • Yen, H.J.1    Hsu, S.H.2    Tsai, C.L.3
  • 231
    • 84869006534 scopus 로고    scopus 로고
    • Oxidative stress and inflammatory responses of rat following acute inhalation exposure to iron oxide nanoparticles
    • Srinivas A, Rao PJ, Selvam G, Goparaju A, Murthy PB, Reddy PN. Oxidative stress and inflammatory responses of rat following acute inhalation exposure to iron oxide nanoparticles. Hum Exp Toxicol. 2012; 31(11):1113–1131.
    • (2012) Hum Exp Toxicol , vol.31 , Issue.11 , pp. 1113-1131
    • Srinivas, A.1    Rao, P.J.2    Selvam, G.3    Goparaju, A.4    Murthy, P.B.5    Reddy, P.N.6
  • 232
    • 80053450672 scopus 로고    scopus 로고
    • Different capacity of monocyte subsets to phagocytose iron-oxide nanoparticles
    • Settles M, Etzrodt M, Kosanke K, et al. Different capacity of monocyte subsets to phagocytose iron-oxide nanoparticles. PLoS One. 2011; 6(10):e25197.
    • (2011) Plos One , vol.6 , Issue.10
    • Settles, M.1    Etzrodt, M.2    Kosanke, K.3
  • 233
    • 66349108461 scopus 로고    scopus 로고
    • Cellular behavior change of macrophage after exposure to nanoparticles
    • Hsiao JK, Weng TI, Tai MF, et al. Cellular behavior change of macrophage after exposure to nanoparticles. J Nanosci Nanotechnol. 2009;9(2):1388–1393.
    • (2009) J Nanosci Nanotechnol , vol.9 , Issue.2 , pp. 1388-1393
    • Hsiao, J.K.1    Weng, T.I.2    Tai, M.F.3
  • 234
    • 53849117141 scopus 로고    scopus 로고
    • Macrophage physiological function after superparamagnetic iron oxide labeling
    • Hsiao JK, Chu HH, Wang YH, et al. Macrophage physiological function after superparamagnetic iron oxide labeling. NMR Biomed. 2008;21(8):820–829.
    • (2008) NMR Biomed , vol.21 , Issue.8 , pp. 820-829
    • Hsiao, J.K.1    Chu, H.H.2    Wang, Y.H.3
  • 235
    • 78650388659 scopus 로고    scopus 로고
    • Small-sized titanium dioxide nanoparticles mediate immune toxicity in rat pulmonary alveolar macrophages in vivo
    • Liu R, Zhang X, Pu Y, et al. Small-sized titanium dioxide nanoparticles mediate immune toxicity in rat pulmonary alveolar macrophages in vivo. J Nanosci Nanotechnol. 2010;10(8):5161–5169.
    • (2010) J Nanosci Nanotechnol , vol.10 , Issue.8 , pp. 5161-5169
    • Liu, R.1    Zhang, X.2    Pu, Y.3
  • 236
    • 84894318718 scopus 로고    scopus 로고
    • Immunostimulatory effects of silica nanoparticles in human monocytes
    • Yang EJ, Choi IH. Immunostimulatory effects of silica nanoparticles in human monocytes. Immune Netw. 2013;13(3):94–101.
    • (2013) Immune Netw , vol.13 , Issue.3 , pp. 94-101
    • Yang, E.J.1    Choi, I.H.2
  • 237
    • 59149102353 scopus 로고    scopus 로고
    • Macrophage responses to silica nanoparticles are highly conserved across particle sizes
    • Waters KM, Masiello LM, Zangar RC, et al. Macrophage responses to silica nanoparticles are highly conserved across particle sizes. Toxicol Sci. 2009;107(2):553–569.
    • (2009) Toxicol Sci , vol.107 , Issue.2 , pp. 553-569
    • Waters, K.M.1    Masiello, L.M.2    Zangar, R.C.3
  • 238
    • 84865795614 scopus 로고    scopus 로고
    • Pulmotoxicological effects caused by long-term titanium dioxide nanoparticles exposure in mice
    • Sun Q, Tan D, Ze Y, et al. Pulmotoxicological effects caused by long-term titanium dioxide nanoparticles exposure in mice. J Hazard Mater. 2012;235–236:47–53.
    • (2012) J Hazard Mater , pp. 47-53
    • Sun, Q.1    Tan, D.2    Ze, Y.3
  • 239
    • 79952108291 scopus 로고    scopus 로고
    • The immune toxicity of titanium dioxide on primary pulmonary alveolar macrophages relies on their surface area and crystal structure
    • Liu R, Yin LH, Pu YP, et al. The immune toxicity of titanium dioxide on primary pulmonary alveolar macrophages relies on their surface area and crystal structure. J Nanosci Nanotechnol. 2010; 10(12):8491–8499.
    • (2010) J Nanosci Nanotechnol , vol.10 , Issue.12 , pp. 8491-8499
    • Liu, R.1    Yin, L.H.2    Pu, Y.P.3
  • 240
    • 80053901859 scopus 로고    scopus 로고
    • Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms
    • Scherbart AM, Langer J, Bushmelev A, et al. Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms. Part Fibre Toxicol. 2011;8:31.
    • (2011) Part Fibre Toxicol , vol.8 , pp. 31
    • Scherbart, A.M.1    Langer, J.2    Bushmelev, A.3
  • 241
    • 84905275305 scopus 로고    scopus 로고
    • Potential impact of metal oxide nanoparticles on the immune system: The role of integrins, L-selectin and the chemokine receptor CXCR4
    • Lozano-Fernández T, Ballester-Antxordoki L, Pérez-Temprano N, et al. Potential impact of metal oxide nanoparticles on the immune system: The role of integrins, L-selectin and the chemokine receptor CXCR4. Nanomedicine. 2014;10(6):1301–1310.
    • (2014) Nanomedicine , vol.10 , Issue.6 , pp. 1301-1310
    • Lozano-Fernández, T.1    Ballester-Antxordoki, L.2    Pérez-Temprano, N.3
  • 242
    • 0024273585 scopus 로고
    • Titanium dioxide induced chemiluminescence of human polymorphonuclear leukocytes
    • Hedenborg M. Titanium dioxide induced chemiluminescence of human polymorphonuclear leukocytes. Int Arch Occup Environ Health. 1988;61(1–2):1–6.
    • (1988) Int Arch Occup Environ Health , vol.61 , Issue.12 , pp. 1-6
    • Hedenborg, M.1
  • 243
    • 84896714721 scopus 로고    scopus 로고
    • Size-dependent effect of zinc oxide on toxicity and inflammatory potential of human monocytes
    • Sahu D, Kannan GM, Vijayaraghavan R. Size-dependent effect of zinc oxide on toxicity and inflammatory potential of human monocytes. J Toxicol Environ Health A. 2014;77(4):177–191.
    • (2014) J Toxicol Environ Health A , vol.77 , Issue.4 , pp. 177-191
    • Sahu, D.1    Kannan, G.M.2    Vijayaraghavan, R.3
  • 244
    • 79957676879 scopus 로고    scopus 로고
    • Cytotoxicity and uptake of zinc oxide nanoparticles leading to enhanced inflammatory cytokines levels in murine macrophages: Comparison with bulk zinc oxide
    • Roy R, Tripathi A, Das M, Dwivedi PD. Cytotoxicity and uptake of zinc oxide nanoparticles leading to enhanced inflammatory cytokines levels in murine macrophages: comparison with bulk zinc oxide. J Biomed Nanotechnol. 2011;7(1):110–111.
    • (2011) J Biomed Nanotechnol , vol.7 , Issue.1 , pp. 110-111
    • Roy, R.1    Tripathi, A.2    Das, M.3    Dwivedi, P.D.4
  • 245
    • 84867487858 scopus 로고    scopus 로고
    • Independent cytotoxic and inflammatory responses to zinc oxide nanoparticles in human monocytes and macrophages
    • Feltis BN, OKeefe SJ, Harford AJ, Piva TJ, Turney TW, Wright PF. Independent cytotoxic and inflammatory responses to zinc oxide nanoparticles in human monocytes and macrophages. Nanotoxicology. 2012;6(7):757–765.
    • (2012) Nanotoxicology , vol.6 , Issue.7 , pp. 757-765
    • Feltis, B.N.1    Okeefe, S.J.2    Harford, A.J.3    Piva, T.J.4    Turney, T.W.5    Wright, P.F.6
  • 246
    • 84878648124 scopus 로고    scopus 로고
    • Zinc oxide nanoparticles induce necrosis and apoptosis in macrophages in a p47phox-and Nrf2-independent manner
    • Wilhelmi V, Fischer U, Weighardt H, et al. Zinc oxide nanoparticles induce necrosis and apoptosis in macrophages in a p47phox-and Nrf2-independent manner. PLoS One. 2013;8(6):e65704.
    • (2013) Plos One , vol.8 , Issue.6
    • Wilhelmi, V.1    Fischer, U.2    Weighardt, H.3


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