Lung exposure to nanoparticles modulates an asthmatic response in a mouse model

European Respiratory Journal

Volumn 37, Issue 2, 2011, Pages 299-309

  Hussain, S ^a,b   Vanoirbeek, J A J ^b   Luyts, K ^b   De Vooght, V ^b   Verbeken, E ^b   Thomassen, L C J ^b   Martens, J A ^b   Dinsdale, D ^c   Boland, S ^a   Marano, F ^a   Nemery, B ^b   Hoet, P H M ^b  

^a Groupe Hospitalier Pitié Salpêtrière   (France)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Diisocyanate induced asthma; Gold; Nanoparticle; Titanium dioxide; Toluene diisocyanate

Indexed keywords

ACETONE; GELATINASE B; GOLD NANOPARTICLE; IMMUNOGLOBULIN E; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; OLIVE OIL; TITANIUM DIOXIDE; TOLUENE DIISOCYANATE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; HISTOPATHOLOGY; IMMUNOGLOBULIN BLOOD LEVEL; LUNG ALVEOLUS MACROPHAGE; LUNG EDEMA; LUNG INJURY; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN ANALYSIS; ROENTGEN SPECTROSCOPY; SENSITIZATION;

ANIMALS; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE MODELS, ANIMAL; EOSINOPHILS; GOLD; IMMUNOGLOBULIN E; LUNG; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; NANOPARTICLES; NEUTROPHILS; PULMONARY EDEMA; TITANIUM; TOLUENE 2,4-DIISOCYANATE;

EID: 79953653520     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00168509     Document Type: Article

References (60)

1. Malo JL, Lemiere C, Gautrin D, et al. Occupational asthma. Curr Opin Pulm Med 2004; 10: 57-61. (Pubitemid 38045902)
2. Boulet LP, Lemiere C, Gautrin D, et al. New insights into occupational asthma. Curr Opin Allergy Clin Immunol 2007; 7: 96-101. (Pubitemid 46095893)
3. Bello D, Herrick CA, Smith TJ, et al. Skin exposure to isocyanates: reasons for concern. Environ Health Perspect 2007; 115: 328-335. (Pubitemid 46554429)
4. Vanoirbeek JA, Tarkowski M, Ceuppens JL, et al. Respiratory response to toluene diisocyanate depends on prior frequency and concentration of dermal sensitization in mice. Toxicol Sci 2004; 80: 310-321. (Pubitemid 39136386)
5. Tarkowski M, Vanoirbeek JA, Vanhooren HM, et al. Immunological determinants of ventilatory changes induced in mice by dermal sensitization and respiratory challenge with toluene diisocyanate. Am J Physiol Lung Cell Mol Physiol 2007; 292: L207-L214. (Pubitemid 46103445)
6. Vanoirbeek JA, De Vooght V, Vanhooren HM, et al. How long do the systemic and ventilatory responses to toluene diisocyanate persist in dermally sensitized mice? J Allergy Clin Immunol 2008; 121: 456-463.
7. Redlich CA, Herrick CA. Lung/skin connections in occupational lung disease. Curr Opin Allergy Clin Immunol 2008; 8: 115-119. (Pubitemid 351654305)
8. Petsonk EL, Wang ML, Lewis DM, et al. Asthma-like symptoms in wood product plant workers exposed to methylene diphenyl diisocyanate. Chest 2000; 118: 1183-1193.
9. Pronk A, Preller L, Raulf-Heimsoth M, et al. Respiratory symptoms, sensitization, and exposure response relationships in spray painters exposed to isocyanates. Am J Respir Crit Care Med 2007; 176: 1090-1097. (Pubitemid 350223755)
10. Ban M, Morel G, Langonne I, et al. TDI can induce respiratory allergy with Th2-dominated response in mice. Toxicology 2006; 218: 39-47. (Pubitemid 41774670)
11. Herrick CA, Das J, Xu L, et al. Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2- induced lung inflammation. J Allergy Clin Immunol 2003; 111: 1087-1094. (Pubitemid 36570870)
12. De Vooght V, Cruz MJ, Haenen S, et al. Ammonium persulfate can initiate an asthmatic response in mice. Thorax 2010; 65: 252-257.
13. The Project on Emerging Nanotechnologies. Woodrow Wilson Database. www.nanotechproject.org. Date last accessed: October 2009. Date last updated: August 2009.
14. Song Y, Li X, Du X. Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granuloma. Eur Respir J 2009; 34: 559-567.
15. Gilbert N. Nanoparticle safety in doubt. Nature 2009; 460: 937.
16. Xia T, Kovochich M, Brant J, et al. Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett 2006; 6: 1794-807. (Pubitemid 44327550)
17. Kaida T, Kobayashi K, Adachi M, et al. Optical characteristics of titanium oxide interference film and the film laminated with oxides and their applications for cosmetics. J Cosmet Sci 2004; 55: 219-220. (Pubitemid 38758804)
18. Long TC, Tajuba J, Sama P, et al. Nanosize titanium dioxide stimulates reactive oxygen species in brain microglia and damages neurons in vitro. Environ Health Perspect 2007; 115: 1631-1637.
19. Sperling RA, Rivera GP, Zhang F, et al. Biological applications of gold nanoparticles. Chem Soc Rev 2008; 37: 1896-1908.
20. Ghosh P, Han G, De M, et al. Gold nanoparticles in delivery applications. Adv Drug Deliv Rev 2008; 60: 1307-1315.
21. De Wall SL, Painter C, Stone JD, et al. Noble metals strip peptides from class II MHC proteins. Nat Chem Biol 2006; 2: 197-201.
22. Cheng Y, Samia C, Meyers JD, et al. Highly efficient drug delivery with gold nanoparticle vectors for in vivo photodynamic therapy of cancer. J Am Chem Soc 2008; 130: 10643-10647.
23. Novelli F, Recine M, Sparatore F, et al. Gold(I) complexes as antimicrobial agents. Farmaco 1999; 54: 232-236.
24. Frampton MW, Utell MJ, Zareba W, et al. Effects of exposure to ultrafine carbon particles in healthy subjects and subjects with asthma. Res Rep Health Eff Inst, 2004: 1-47.
25. von Klot S, Wolke G, Tuch T, et al. Increased asthma medication use in association with ambient fine and ultrafine particles. Eur Respir J 2002; 20: 691-702.
26. Warheit DB, Webb TR, Sayes CM, et al. Pulmonary instillation studies with nanoscale TiO2 rods and dots in rats: toxicity is not dependent upon particle size and surface area. Toxicol Sci 2006; 91: 227-236.
27. Sayes CM, Reed KL, Warheit DB. Assessing toxicity of fine and nanoparticles: comparing in vitro measurements to in vivo pulmonary toxicity profiles. Toxicol Sci 2007; 97: 163-180. (Pubitemid 47072165)
28. Hussain S, Boland S, Baeza-Squiban A, et al. Oxidative stress and proinflammatory effects of carbon black and titanium dioxide nanoparticles: role of particle surface area and internalized amount. Toxicology 2009; 260: 142-149.
29. Val S, Hussain S, Boland S, et al. Carbon black and titanium dioxide nanoparticles induce pro-inflammatory responses in bronchial epithelial cells: need for multiparametric evaluation due to adsorption artifacts. Inhal Toxicol 2009; 21: 115-122.
30. Karlsson HL, Gustafsson J, Cronholm P, et al. Size-dependent toxicity of metal oxide particles: a comparison between nano- and micrometer size. Toxicol Lett 2009; 188: 112-118.
31. Hussain S, Thomassen LC, Ferecatu I, et al. Carbon black and titanium dioxide nanoparticles elicit distinct apoptotic pathways in bronchial epithelial cells. Part Fibre Toxicol 2010; 7: 10.
32. Berne BJ, Pecora R. Dynamic Light Scattering with Applications to Chemistry, Biology, and Physics. New York, Wiley; 1976.
33. De Vooght V, Vanoirbeek JA, Haenen S, et al. Oropharyngeal aspiration: an alternative route for challenging in a mouse model of chemical-induced asthma. Toxicology 2009; 259: 84-89.
34. Vanoirbeek JA, Rinaldi M, De Vooght V, et al. Noninvasive and invasive pulmonary function in mouse models of obstructive and restrictive respiratory diseases. Am J Respir Cell Mol Biol 2009; 42: 96-104.
35. Kahru A, Savolainen K. Potential hazard of nanoparticles: from properties to biological and environmental effects. Toxicology 2010; 269: 89-91.
36. Savolainen K, Alenius H, Norppa H, et al. Risk assessment of engineered nanomaterials and nanotechnologies: a review. Toxicology 2010; 269: 92-104.
37. Larsen ST, Roursgaard M, Jensen KA, et al. Nano titanium dioxide particles promote allergic sensitization and lung inflammation in mice. Basic Clin Pharmacol Toxicol 2010; 106: 114-117.
38. Alessandrini F, Schulz H, Takenaka S, et al. Effects of ultrafine carbon particle inhalation on allergic inflammation of the lung. J Allergy Clin Immunol 2006; 117: 824-830.
39. Inoue K, Takano H, Yanagisawa R, et al. Effects of nanoparticles on lung physiology in the presence or absence of antigen. Int J Immunopathol Pharmacol 2007; 20: 737-744.
40. Takano H, Ichinose T, Miyabara Y, et al. Inhalation of diesel exhaust enhances allergen-related eosinophil recruitment and airway hyperresponsiveness in mice. Toxicol Appl Pharmacol 1998; 150: 328-337. (Pubitemid 28302517)
41. Park EJ, Yoon J, Choi K, et al. Induction of chronic inflammation in mice treated with titanium dioxide nanoparticles by intratracheal instillation. Toxicology 2009; 260: 37-46.
42. 2 and quartz. Toxicol Lett 2009; 186: 152-159.
43. NIOSH. Evaluation of Health Hazard and Recommandations for Occupational Exposure to Titanium Dioxide.www.cdc.gov/niosh/ review/public/tio2/pdfs/ TIO2Draft.pdf Date last accessed: November, 2010. Date last updated: November 22, 2005.
44. Inoue K, Takano H, Yanagisawa R, et al. Size effects of latex nanomaterials on lung inflammation in mice. Toxicol Appl Pharmacol 2009; 234: 68-76.
45. Ban M, Langonne I, Huguet N, et al. Inhaled chemicals may enhance allergic airway inflammation in ovalbumin-sensitised mice. Toxicology 2006; 226: 161-171. (Pubitemid 44287167)
46. Marraccini P, Brass DM, Hollingsworth JW, et al. Bakery flour dust exposure causes non-allergic inflammation and enhances allergic airway inflammation in mice. Clin Exp Allergy 2008; 38: 1526-1535.
47. Robbins RA, Russ WD, Thomas KR, et al. Complement component C5 is required for release of alveolar macrophage-derived neutrophil chemotactic activity. Am Rev Respir Dis 1987; 135: 659-664. (Pubitemid 17041601)
48. Hashimoto S, Pittet JF, Hong K, et al. Depletion of alveolar macrophages decreases neutrophil chemotaxis to Pseudomonas airspace infections. Am J Physiol 1996; 270: L819-L828.
49. Desouza IA, Hyslop S, Franco-Penteado CF, et al. Mouse macrophages release a neutrophil chemotactic mediator following stimulation by staphylococcal enterotoxin type A. Inflamm Res 2001; 50: 206-212. (Pubitemid 32382246)
50. Alberg T, Cassee FR, Groeng EC, et al. Fine ambient particles from various sites in europe exerted a greater IgE adjuvant effect than coarse ambient particles in a mouse model. J Toxicol Environ Health A 2009; 72: 1-13.
51. Nygaard UC, Samuelsen M, Aase A, et al. The capacity of particles to increase allergic sensitization is predicted by particle number and surface area, not by particle mass. Toxicol Sci 2004; 82: 515-524. (Pubitemid 39600079)
52. Samuelsen M, Nygaard UC, Lovik M. Allergy adjuvant effect of particles from wood smoke and road traffic. Toxicology 2008; 246: 124-131.
53. Riedl MA, Nel AE. Importance of oxidative stress in the pathogenesis and treatment of asthma. Curr Opin Allergy Clin Immunol 2008; 8: 49-56.
54. van Zijverden M, Granum B. Adjuvant activity of particulate pollutants in different mouse models. Toxicology 2000; 152: 69-77.
55. Murphy SA, BeruBe KA, Pooley FD, et al. The response of lung epithelium to well characterised fine particles. Life Sci 1998; 62: 1789-1799. (Pubitemid 28189415)
56. Devalia JL, Rusznak C, Davies RJ. Allergen/irritant interaction: its role in sensitization and allergic disease. Allergy 1998; 53: 335-345. (Pubitemid 28168193)
57. Vermeer PD, Denker J, Estin M, et al. MMP9 modulates tight junction integrity and cell viability in human airway epithelia. Am J Physiol Lung Cell Mol Physiol 2009; 296: L751-L762.
58. Palomäki J, Karisola P, Pylkkanen L, et al. Engineered nanomaterials cause cytotoxicity and activation on mouse antigen presenting cells. Toxicology 2010; 267: 125-131.
59. Monteiller C, Tran L, MacNee W, et al. The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: the role of surface area. Occup Environ Med 2007; 64: 609-615. (Pubitemid 47345256)
60. -/- mice. Part Fibre Toxicol 2009; 6: 2.