Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms

Particle and Fibre Toxicology

Volumn 8, Issue , 2011, Pages

  Scherbart, Agnes M ^a   Langer, Julia ^b   Bushmelev, Alexey ^c   van Berlo, Damiion ^a   Haberzettl, Petra ^a   van Schooten, Frederik Jan ^d   Schmidt, Annette M ^c   Rose, Christine R ^b   Schins, Roel P F ^a   Albrecht, Catrin ^a  

^a IUF LEIBNIZ RESEARCH INSTITUTE FOR ENVIRONMENTAL MEDICINE   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

^d MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Agglomeration; Nr8383 cells; Particle internalization; Size distribution; Titanium dioxide

Indexed keywords

ANTIBODY; CALCIUM; CHLORPROMAZINE; CYTOCHALASIN D; FC RECEPTOR II ANTIBODY; FILIPIN; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; REACTIVE OXYGEN METABOLITE; TITANIUM DIOXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; FC RECEPTOR; HEME OXYGENASE; NANOPARTICLE; SILICON DIOXIDE; TITANIUM;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; COATED VESICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DYNAMIC LIGHT SCATTERING; ENDOCYTOSIS; GENE EXPRESSION; INFLAMMATION; INTERNALIZATION; LIGHT SCATTERING; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE ACTIVATION; NONHUMAN; OXIDATIVE STRESS; PARTICLE SIZE; PHAGOCYTOSIS; PHYSICAL CHEMISTRY; PINOCYTOSIS; PRIORITY JOURNAL; RAT; THERMOGRAVIMETRY; TRANSMISSION ELECTRON MICROSCOPY; AIR POLLUTANT; ANIMAL; CELL LINE; CELL SURVIVAL; COMPARATIVE STUDY; DRUG EFFECT; GENETICS; IMMUNOLOGY; METABOLISM; ULTRASTRUCTURE;

RATTUS;

AIR POLLUTANTS; ANIMALS; CALCIUM; CELL LINE; CELL SURVIVAL; CHLORPROMAZINE; CYTOCHALASIN D; ENDOCYTOSIS; GENE EXPRESSION; HEME OXYGENASE (DECYCLIZING); INTERLEUKIN-1BETA; MACROPHAGE ACTIVATION; MACROPHAGES, ALVEOLAR; NANOPARTICLES; NITRIC OXIDE SYNTHASE TYPE II; PARTICLE SIZE; RATS; REACTIVE OXYGEN SPECIES; RECEPTORS, IGG; SILICON DIOXIDE; TITANIUM; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80053901859     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/1743-8977-8-31     Document Type: Article

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