Inhibition of enzyme activity by nanomaterials: Potential mechanisms and implications for nanotoxicity testing

Nanotoxicology

Volumn 6, Issue 5, 2012, Pages 514-525

  MacCormack, Tyson J ^a   Clark, Rhett J ^b   Dang, Michael K M ^b   Ma, Guibin ^b   Kelly, Joel A ^b   Veinot, Jonathan G C ^b   Goss, Greg G ^a  

^a MOUNT ALLISON UNIVERSITY   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Biochemistry; Ecotoxicology; Nanoparticles; Nanotoxicology; Toxicology

Indexed keywords

ALBUMIN; CADMIUM SELENIDE; GOLD NANOPARTICLE; LACTATE DEHYDROGENASE; NANOMATERIAL; SILICON;

ANIMAL TISSUE; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ISOELECTRIC POINT; NANOCHEMISTRY; NANOTOXICOLOGY; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RABBIT; TISSUE HOMOGENATE;

ANALYSIS OF VARIANCE; ANIMALS; CIRCULAR DICHROISM; HYDROGEN-ION CONCENTRATION; KINETICS; L-LACTATE DEHYDROGENASE; METAL NANOPARTICLES; RABBITS; TOXICITY TESTS;

EID: 84863802840     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2011.587904     Document Type: Article

References (36)

1. Balogh L, Nigavekar SS, Nair BM, Lesniak W, Zhang CS, Lok Y, Kariapper MST, El Jawahri A, Llanes M, Bolton B, et al. 2007 Significant effect of size on the in vivo biodistribution of gold composite nanodevices in mouse tumor models. Nanomed: Nanotechnol Biol Med 3:281-296.
2. Bayraktar H, Ghosh PS, Rotello VM, Knapp MJ. 2006. Disruption of protein-protein interactions using nanoparticles: Inhibition of cytochrome C peroxidase. Chem Comm 2006:1390-1392.
3. Bolotina IA, Chekov VO, Lugauskus VY. 1979. Determination of the secondary structures of proteins by circular dichroism spectra. Calculation of the protein basic circular dichroism spectra for antiparallel and parallel b-structures and b-bends. Int J Quant Chem 16:819-824.
4. Borm P. 2006. Research strategies for safety evaluation of nanomaterials; Part V: Role of dissolution in biological fate and effects of nanoscale particles. Toxicol Sci 90:23-32.
5. Cedervall T, Lynch I, Lindman S, Berggård T, Thulin E, Nilsson H, Dawson KA, Linse S. 2007. Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles. Proc Natl Acad Sci 104:2050-2055.
6. Clark RJ, Dang MKM, Veinot JGC. 2010. Exploration of organic acid chain length on water soluble silicon quantum dot surfaces. Langmuir 26:15657-15664.
7. Corbierre MK. 2004. Gold nanoparticles: Tailored preparation and assembly in 2- and 3-dimensions [dissertation]. Montréal QC: McGill University. 246 pp. Available from: McGill University Library Montréal Québec AS42 M3 2004 C673.
8. Deguchi S, Yamazaki T, Mukai S, Usami R, Horikoshi K. 2007. Stabilization of C60 nanoparticles by protein adsorption and its implications for toxicity studies. Chem Res Toxicol 20:854-858.
9. Derfus AM, Chan WCW, Bhatia SN. 2004. Probing the cytotoxicity of semiconductor quantum dots. Nano Lett 4:11-18.
10. Dym O, Pratt EA, Ho C, Eisenberg D. 2000. The crystal structure of d-lactate dehydrogenase a peripheral membrane respiratory enzyme. Proc Nat Acad Sci USA 97:9413-9418.
11. Ellis RJ. 2001. Macromolecular crowding: Obvious but underappreciated. Trends Biochem Sci 26:597-604.
12. Fei L, Perrett S. 2009. Effect of nanoparticles on protein folding and fibrillogenesis. Int J Mol Sci 10:646-655.
13. Fischer NO, McIntosh CM, Simard JM, Rotello VM. 2002. Inhibition of chymotrypsin through surface binding using nanoparticle-based receptors. Proc Nat Acad Sci USA 99:5018-5023.
14. Ge Y, Zhang Y, Xia J, Ma M, He S, Nie F, Gu N. 2009. Effect of surface charge and agglomerate degree of magnetic iron oxide nanoparticles on KB cellular uptake in vitro. Colloids Surfaces B: Biointerfaces 73:294-301.
15. Haun JB, Yoon T, Lee H, Weissleder R. 2010. Magnetic nanoparticle biosensors. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2:291-304.
16. Hessel CM, Henderson EJ, Veinot JGC. 2006. Hydrogen silsesquioxane: A molecular precursor for nanocrystalline Si-SiO2 composites and freestanding hydride-surface-terminated silicon nanoparticles. Chem Mat 18:6139-6146.
17. Hong R, Fischer NO, Verma A, Goodman CM, Emrick T, Rotello VM. 2004. Control of protein structure and function through surface recognition by tailored nanoparticle scaffolds. J Am Chem Soc 126:739-743.
18. Hyung H, Fortner JD, Hughes JB, Kim J. 2007. Natural organic matter stabilizes carbon nanotubes in the aqueous phase. Environ Sci Technol 41:179-184.
19. Karajanagi SS, Vertegel AA, Kane RS, Dordick JS. 2004. Structure and function of enzymes adsorbed onto single-walled carbon nanotubes. Langmuir 20:11594-11599.
20. Kroll A, Pillukat MH, Hahn D, Schnekenburger J. 2009. Current in vitro methods in nanoparticle risk assessment: Limitations and challenges. Eur J Pharm Biopharm 72:370-377.
21. Kumar S, Harrison N, Richards-Kortum R, Sokolov K. 2007. Plasmonic nanosensors for imaging intracellular biomarkers in live cells. Nano Lett 7:1338-1343.
22. Lorenz MR, Holzapfel V, Musyanovych A, Nothelfer K,Walther P, Frank H, Landfester K, Schrezenmeier H, Mailänder V. 2006. Uptake of functionalized fluorescent-labeled polymeric particles in different cell lines and stem cells. Biomaterials 27:2820-2828.
23. Lovric J, Bazzi HS, Cuie Y, Fortin GRA, Winnik FM,Maysinger D. 2005. Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots. J Mol Med 83:377-385.
24. Lundqvist M, Stigler J, Elia G, Lynch I, Cedervall T, Dawson KA. 2008. Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc Natl Acad Sci USA 105:14265-14270.
25. MacCormack TJ, Goss GG. 2008. Identifying and predicting biological risks associated with manufactured nanoparticles in aquatic ecosystems. J Industrial Ecol 12:286-296.
26. Martin KR. 2007. The chemistry of silica and its potential health benefits. J Nutrition Health Aging 11:94-98.
27. Mayer A, Vadon M, Rinner B, Novak A, Wintersteiger R, Fröhlich E. 2009. The role of nanoparticle size in hemocompatibility. Toxicology 258:139-147.
28. Park J, Gu L, von Maltzahn G, Ruoslahti E, Bhatia SN, Sailor MJ. 2009. Biodegradable luminescent porous silicon nanoparticles for in vivo applications. Nature Mat 8:331-336.
29. Pfleiderer G, Nagal G, Bühler H. 1991. Limited proteolysis of lactate dehydrogenase from porcine heart with trypsin: Characterization and reactivation of the fragments. Experientia 47:470-475.
30. Robberecht H, Van Cauwenbergh R, Van Vlaslaer V, Hermans N. 2009. Dietary silicon intake in Belgium: Sources, availability from foods, and human serum levels. Sci Total Environ 407:4777-4782.
31. Sawant RM, Hurley JP, Salmaso A, Kale A, Tolcheva E, Levchenko TS, Torchilin VP. 2006. 'Smart' drug delivery systems: Double-targeted pH-responsive pharmaceutical nanocarriers. Bioconjugate Chem 17:943-949.
32. Vallhov H, Gabrielsson S, Stromme M, Scheynius A, Garcia-Bennett AE. 2007. Mesoporous silica particles induce size dependent effects on human dendritic cells. Nano Lett 7:3576-3582.
33. Yoo EJ, Li T, Park HG, Chang YK. 2008. Size-dependent flocculation behavior of colloidal Au nanoparticles modified with various biomolecules. Ultramicroscopy 108:1273-1277.
34. Zhao L, Liu R, Zhao X, Yang B, Gao C, Hao X, Wu Y. 2009. New strategy for the evaluation of CdTe quantum dot toxicity targeted to bovine serum albumin. Sci Total Environ 407:5019-5023.
35. Zheng YB, Meng FG, Chen BY, Wang XC. 2002. Inactivation and conformational changes of lactate dehydrogenase from porcine heart in sodium dodecyl sulfate solutions. Int J Biol Macromol 31:97-102.
36. Zhong P, Yu Y, Wu J, Lai Y, Chen B, Long Z, Liang C. 2006 Preparation and application of functionalized nanoparticles of CdSe capped with 11-mercaptoundecanoic acid as a fluorescence probe. Talanta 70:902-906.