The capacity of particles to increase allergic sensitization is predicted by particle number and surface area, not by particle mass

Toxicological Sciences

Volumn 82, Issue 2, 2004, Pages 515-524

  Nygaar, Unni Cecilie ^a   Samuelsen, Mari ^a   Aase, Audun ^a   Løvik, Martinus ^a  

^a NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

Author keywords

Adjuvant effect; Allergy; IgE; Mice; Particle size; PM

Indexed keywords

CARBON; CD19 ANTIGEN; CD23 ANTIGEN; CD86 ANTIGEN; IMMUNOGLOBULIN E; INTERLEUKIN 10; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OVALBUMIN; POLYSTYRENE;

AIR PARTICLE CONTROL; AIRBORNE PARTICLE; ALLERGIC REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ANTIGEN EXPRESSION; ARTICLE; CELL COUNT; CONTROLLED STUDY; CYTOKINE PRODUCTION; EX VIVO STUDY; EXHAUST GAS; FEMALE; FOOT PAD; IMMUNE RESPONSE; LINEAR REGRESSION ANALYSIS; LYMPH NODE; MOUSE; NONHUMAN; PARTICLE SIZE; PREDICTION; PRIMARY IMMUNE RESPONSE; SENSITIZATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, SURFACE; CARBON; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HYPERSENSITIVITY; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; LYMPH NODES; LYMPHOCYTE COUNT; LYMPHOCYTES; MICE; MICE, INBRED BALB C; OVALBUMIN; PARTICLE SIZE; PHENOTYPE; POLYSTYRENES; PREDICTIVE VALUE OF TESTS; REGRESSION ANALYSIS; SURFACE PROPERTIES; THYMIDINE; VEHICLE EMISSIONS;

EID: 10044282922     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfh287     Document Type: Article

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