Effects of sustained stimulation with multi-wall carbon nanotubes on immune and inflammatory responses in mice

Journal of Toxicological Sciences

Volumn 37, Issue 1, 2012, Pages 177-189

  Yamaguchi, Atsumi ^a   Fujitani, Tomoko ^a   Ohyama, Ken Ichi ^a   Nakae, Dai ^a   Hirose, Akihiko ^b   Nishimura, Tetsuji ^b   Ogata, Akio ^a  

^a TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Hazard characterization; Immunotoxicity; Inflammation; Multi wall carbon nanotube; Nanomaterial

Indexed keywords

ALPHA4 INTEGRIN; CARBOXYMETHYLCELLULOSE; CROCIDOLITE; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN M; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 33; INTERLEUKIN 4; INTERLEUKIN 5; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MULTI WALLED NANOTUBE; MYELOID DIFFERENTIATION FACTOR 88; OVALBUMIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FIBROMA; GRANULOCYTE; IMMUNE RESPONSE; INFLAMMATION; LEUKOCYTE; LEUKOCYTE ADHERENCE; LIVER STRUCTURE; MALE; MONOCYTE; MOUSE; NONHUMAN; PERITONEAL CAVITY; PERITONEUM CELL; PROTEIN EXPRESSION; TH2 CELL;

MUS;

EID: 84856888108     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.37.177     Document Type: Article

References (38)

1. Amatucci, A., Novobrantseva, T., Gilbride, K., Brickelmaier, M., Hochman, P. and Ibraghimov, A. (2007): Recombinant ST2 boosts hepatic Th2 response in vivo. J. Leukoc. Biol., 82, 124-132
2. Cho, J.Y., Miller, M., Baek, K.J., Han, J.W., Nayar, J., Lee, S.Y., McElwain, K., McElwain, S., Friedman, S. and Broide, D.H. (2004): Inhibition of airway remodeling in IL-5-deficient mice. J. Clin. Invest., 113, 551-560
3. Choi, M., Cho, W.S., Han, B.S., Cho, M., Kim, S.Y., Yi, J.Y., Ahn, B., Kim, S.H. and Jeong, J. (2008): Transient pulmonary fibrogenic effect induced by intratracheal instillation of ultrafine amorphous silica in A/J mice. Toxicol. Lett., 182, 97-101
4. Chow, J.Y., Wong, C.K., Cheung, P.F. and Lam, C.W. (2010): Intracellular signaling mechanisms regulating the activation of human eosinophils by the novel Th2 cytokine IL-33: implications for allergic inflammation. Cell. Mol. Immunol., 7, 26-34
5. Doherty, T. and Broide, D. (2007): Cytokines and growth factors in airway remodeling in asthma. Curr. Opin. Immunol., 19, 676-680
6. Dostert, C., Petrilli, V., Van Bruggen, R., Steele, C., Mossman, B.T. and Tschopp, J. (2008): Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science, 320, 674-677
7. Finkelman, F.D., Wynn, T.A., Donaldson, D.D. and Urban, J.F. (1999): The role of IL-13 in helminth-induced inflammation and protective immunity against nematode infections. Curr. Opin. Immunol., 11, 420-426
8. Flood-Page, P., Menzies-Gow, A., Phipps, S., Ying, S., Wangoo, A., Ludwig, M.S., Barnes, N., Robinson, D. and Kay, A.B. (2003): Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J. Clin. Invest., 112, 1029-1036
9. Hei, T.K., Piao, C.Q., He, Z.Y., Vannais, D. and Waldren, C.A. (1992): Chrysotile fiber is a strong mutagen in mammalian cells. Cancer Res., 52, 6305-6309
10. Hornung, V., Bauernfeind, F., Halle, A., Samstad, E.O., Kono, H., Rock, K.L., Fitzgerald, K.A. and Latz, E. (2008): Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat. Immunol., 9, 847-856
11. Inoue, K., Koike, E., Yanagisawa, R., Hirano, S., Nishikawa, M. and Takano, H. (2009): Effects of multi-walled carbon nanotubes on a murine allergic airway inflammation model. Toxicol. Appl. Pharmacol., 237, 306-316
12. Ito, T., Inouye, K., Fujimaki, H., Tohyama, C. and Nohara, K. (2002): Mechanism of TCDD-induced suppression of antibody production: effect on T cell-derived cytokine production in the primary immune reaction of mice. Toxicol. Sci., 70, 46-54
13. Izuhara, K. (2003): The role of interleukin-4 and interleukin-13 in the non-immunologic aspects of asthma pathogenesis. Clin. Chem. Lab. Med., 41, 860-864
14. Komai-Koma, M., Xu, D., Li, Y., McKenzie, A.N., McInnes, I.B. and Liew, F.Y. (2007): IL-33 is a chemoattractant for human Th2 cells. Eur. J. Immunol., 37, 2779-2786
15. Kondo, Y., Yoshimoto, T., Yasuda, K., Futatsugi-Yumikura, S., Morimoto, M., Hayashi, N., Hoshino, T., Fujimoto, J. and Nakanishi, K. (2008): Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system. Int. Immunol., 20, 791-800
16. Kroeger, K.M., Sullivan, B.M. and Locksley, R.M. (2009): IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88-and p38alpha-dependent pathway. J. Leukoc. Biol., 86, 769-778
17. Manhiani, M.M., Quigley, J.E., Socha, M.J., Motamed, K. and Imig, J.D. (2007): IL6 suppression provides renal protection independent of blood pressure in a murine model of salt-sensitive hypertension. Kidney Blood Press Res., 30, 195-202
18. Martinon, F., Burns, K. and Tschopp, J. (2002): The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol. Cell., 10, 417-426
19. McClintock, S.D., Barron, A.G., Olle, E.W., Deogracias, M.P., Warner, R.L., Opp, M and Johnson, K.J. (2005): Role of interleukin-6 in immune complex induced models of vascular injury. Inflammation, 29, 154-162
20. Mitchell, L.A., Gao, J., Wal, R.V., Gigliotti, A., Burchiel, S.W. and McDonald, J.D. (2007): Pulmonary and systemic immune response to inhaled multiwalled carbon nanotubes. Toxicol. Sci., 100, 203-214
21. Mossman, B.T., Bignon, J., Corn, M., Seaton, A. and Gee, J.B. (1990): Asbestos: scientific developments and implications for public policy. Science, 247, 294-301
22. Mossman, B.T. and Churg, A. (1998): Mechanisms in the pathogenesis of asbestosis and silicosis. Am. J. Respir. Crit. Care. Med., 157, 1666-1680
23. Moussion, C., Ortega, N. and Girard, J.P. (2008): The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'? PLoS One, 3, e3331.
24. Nile, C.J., Barksby, E., Jitprasertwong, P., Preshaw, P.M. and Taylor, J.J. (2010): Expression and regulation of interleukin-33 in human monocytes. Immunology, 130, 172-180
25. Nygaard, U.C., Hansen, J.S., Samuelsen, M., Alberg, T., Marioara, C.D. and Lovik, M. (2009): Single-walled and multi-walled carbon nanotubes promote allergic immune responses in mice. Toxicol. Sci., 109, 113-123
26. Park, E.J., Cho, W.S., Jeong, J., Yi, J., Choi, K. and Park, K. (2009): Pro-inflammatory and potential allergic responses resulting from B cell activation in mice treated with multi-walled carbon nanotubes by intratracheal instillation. Toxicology, 259, 113-121
27. Petrilli, V., Papin, S., Dostert, C., Mayor, A., Martinon, F. and Tschopp, J. (2007): Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ 14, 1583-1589
28. Poland, C.A., Duffin, R., Kinloch, I., Maynard, A., Wallace, W.A., Seaton, A., Stone, V., Brown, S., Macnee, W. and Donaldson, K. (2008): Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat. Nanotechnol., 3, 423-428
29. Porter, D.W., Hubbs, A.F., Mercer, R.R., Wu, N., Wolfarth, M.G., Sriram, K., Leonard, S., Battelli, L., Schwegler-Berry, D., Friend, S., Andrew, M., Chen, B.T., Tsuruoka, S., Endo, M. and Castranova, V. (2010): Mouse pulmonary dose-and time courseresponses induced by exposure to multi-walled carbon nanotubes. Toxicology, 269, 136-147
30. Ryman-Rasmussen, J.P., Cesta, M.F., Brody, A.R., Shipley-Phillips, J.K., Everitt, J.I., Tewksbury, E.W., Moss, O.R., Wong, B.A., Dodd, D.E., Andersen, M.E. and Bonner, J.C. (2009a): Inhaled carbon nanotubes reach the subpleural tissue in mice. Nat. Nanotechnol., 4, 747-751
31. Ryman-Rasmussen, J.P., Tewksbury, E.W., Moss, O.R., Cesta, M.F., Wong, B.A. and Bonner, J.C. (2009b): Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma. Am. J. Respir. Cell. Mol. Biol., 40, 349-358
32. Sakamoto, Y., Nakae, D., Fukumori, N., Tayama, K., Maekawa, A., Imai, K., Hirose, A., Nishimura, T., Ohashi, N. and Ogata, A. (2009): Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats. J. Toxicol. Sci., 34, 65-76
33. Schmid-Grendelmeier, P., Altznauer, F., Fischer, B., Bizer, C., Straumann, A., Menz, G., Blaser, K., Wuthrich, B. and Simon, H.U. (2002): Eosinophils express functional IL-13 in eosinophilic inflammatory diseases. J. Immunol., 169, 1021-1027
34. Schmitz, J., Owyang, A., Oldham, E., Song, Y., Murphy, E., McClanahan, T.K., Zurawski, G., Moshrefi, M., Qin, J., Li, X., Gorman, D.M., Bazan, J.F. and Kastelein, R.A. (2005): IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity, 23, 479-490
35. Tabet, L., Bussy, C., Amara, N., Setyan, A., Grodet, A., Rossi, M.J., Pairon, J.C., Boczkowski, J. and Lanone, S. (2009): Adverse effects of industrial multiwalled carbon nanotubes on human pulmonary cells. J. Toxicol. Environ. Health A, 72, 60-73
36. Takagi, A., Hirose, A., Nishimura, T., Fukumori, N., Ogata, A., Ohashi, N., Kitajima, S. and Kanno, J. (2008): Induction of mesothelioma in p53+/-mouse by intraperitoneal application of multi-wall carbon nanotube. J. Toxicol. Sci., 33, 105-116
37. Teeguarden, J.G., Webb-Robertson, B.J., Waters, K.M., Murray, A.R., Kisin, E.R., Varnum, S.M., Jacobs, J.M., Pounds, J.G., Zanger, R.C. and Shvedova, A.A. (2011): Comparative proteomics and pulmonary toxicity of instilled single-walled carbon nanotubes, crocidolite asbestos, and ultrafine carbon black in mice. Toxicol. Sci., 120, 123-135
38. Yazdi, A.S., Guarda, G., Riteau, N., Drexler, S.K., Tardivel, A., Couillin, I. and Tschopp, J. (2010): Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1beta. Proc. Natl. Acad. Sci. USA, 107, 19449-19454.