Incompatibility of silver nanoparticles with lactate dehydrogenase leakage assay for cellular viability test is attributed to protein binding and reactive oxygen species generation

Toxicology Letters

Volumn 225, Issue 3, 2014, Pages 422-432

  Oh, Seok Jeong ^a   Kim, Hwa ^a   Liu, Yingqiu ^a   Han, Hyo Kyung ^a   Kwon, Kyenghee ^a   Chang, Kyung Hwa ^a   Park, Kwangsik ^b   Kim, Younghun ^c   Shim, Kyuhwan ^d   An, Seong Soo A ^d   Lee, Moo Yeol ^a  

^a Dongguk University   (South Korea)

^b Dongduk Woman s University   (South Korea)

^c Kwangwoon University   (South Korea)

^d Gachon University   (South Korea)

Author keywords

Cytotoxicity; Lactate dehydrogenase leakage assay; Protein adsorption; Reactive oxygen species; Silver nanoparticles

Indexed keywords

LACTATE DEHYDROGENASE; REACTIVE OXYGEN METABOLITE; SILVER NANOPARTICLE; ACETYLCYSTEINE; FORMAZAN; METAL NANOPARTICLE; MTT FORMAZAN; SILVER; TETRAZOLIUM;

ARTICLE; CELL LYSATE; CELL MEMBRANE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY ASSAY; ELECTROSPRAY; ENZYME ACTIVITY; ENZYME ANALYSIS; HUMAN; HUMAN CELL; HYDRODYNAMICS; LIGHT SCATTERING; LIQUID CHROMATOGRAPHY; PHYSICAL CHEMISTRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; TANDEM MASS SPECTROMETRY; CELL SURVIVAL; DRUG EFFECTS; ELECTROSPRAY MASS SPECTROMETRY; HELA CELL LINE; METABOLISM; TOXICITY; ULTRASTRUCTURE;

ACETYLCYSTEINE; CELL SURVIVAL; CHROMATOGRAPHY, LIQUID; FORMAZANS; HELA CELLS; HUMANS; L-LACTATE DEHYDROGENASE; METAL NANOPARTICLES; REACTIVE OXYGEN SPECIES; SILVER; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TETRAZOLIUM SALTS;

EID: 84893655513     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.01.015     Document Type: Article

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