Impact of silver nanoparticles and silver ions on innate immune cells

Journal of Biomedical Nanotechnology

Volumn 10, Issue 6, 2014, Pages 1146-1156

  Haase, Hajo ^a   Fahmi, Amir ^b   Mahltig, Boris ^c  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b RHINE WAAL UNIVERSITY OF APPLIED SCIENCES   (Germany)

^c NIEDERRHEIN UNIVERSITY OF APPLIED SCIENCES   (Germany)

Author keywords

Granulocytes; Immune function; Macrophages

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; DENDRIMERS; ENZYME ACTIVITY; MACROPHAGES; MEDICAL APPLICATIONS; METAL IONS; MOLECULAR OXYGEN; NANOPARTICLES; PARTICLES (PARTICULATE MATTER);

ANTI-BACTERIAL AGENTS; ANTIBACTERIAL PROPERTIES; GRANULOCYTES; IMMUNE FUNCTION; IMMUNOMODULATORY ACTIVITIES; INNATE IMMUNE SYSTEMS; POLYESTER DENDRIMERS; REACTIVE OXYGEN SPECIES;

SILVER;

DENDRIMER; ION; NITRIC OXIDE; PHOSPHOPROTEIN PHOSPHATASE; POLYESTER; REACTIVE OXYGEN METABOLITE; SILVER; SILVER NANOPARTICLE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYDROXYLATION; INNATE IMMUNITY; MACROPHAGE; NEUTROPHIL; NONHUMAN; OXIDATION; PHAGOCYTOSIS; PROMOTER REGION; PROTEIN PHOSPHORYLATION; RESPIRATORY BURST; SECOND MESSENGER; SYNTHESIS;

ANIMALS; CELLS, CULTURED; HUMANS; IMMUNITY, INNATE; IONS; LEUKOCYTES; MACROPHAGES; MATERIALS TESTING; METAL NANOPARTICLES; MICE; REACTIVE OXYGEN SPECIES; SILVER;

EID: 84898403565     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2014.1784     Document Type: Article

References (28)

1. H. J. Klasen, A historical review of the use of silver in the treatment of burns. II. Renewed interest for silver. Burns 26, 131 (2000).
2. M. Rai, A. Yadav, and A. Gade, Silver nanoparticles as a new generation of antimicrobials. Biotechnol. Adv. 27, 76 (2009).
3. J. Ai, E. Biazar, M. Jafarpour, M. Montazeri, A. Majdi, S. Aminifard, M. Zafari, H. R. Akbari, and H. G. Rad, Nanotoxicology and nanoparticle safety in biomedical designs. Int. J. Nanomedicine. 6, 1117 (2011).
4. B. Mahltig, N. Cheval, V. Astachov, Malkoch, Montanez, Haase, and A. Fahmi, Hydroxyl functional polyester dendrimers as stabilizing agent for preparation of colloidal silver particles-a study in respect to antimicrobial properties and toxicity against human cells. J. Colloid Polym. Sci. 290, 1413 (2012).
5. Agency for Toxic Substances and Disease Registry, Toxicological profile for silver., U. S. Public Health Service (1990), p. 39.
6. R. P. Singh and P. Ramarao, Cellular uptake, intracellular trafficking and cytotoxicity of silver nanoparticles. Toxicol. Lett. 213, 249 (2012).
7. K. Loeschner, N. Hadrup, K. Qvortrup, A. Larsen, X. Gao, U. Vogel, A. Mortensen, H. R. Lam, and E. H. Larsen, Distribution of silver in rats following 28 days of repeated oral exposure to silver nanoparticles or silver acetate. Part Fibre. Toxicol. 8, 18 (2011).
8. S. Takenaka, E. Karg, C. Roth, H. Schulz, A. Ziesenis, U. Heinzmann, P. Schramel, and J. Heyder, Pulmonary and systemic distribution of inhaled ultrafine silver particles in rats. Environ. Health Perspect. 109, 547 (2001).
9. L. J. Locht, A. Larsen, M. Stoltenberg, and G. Danscher, Cultured macrophages cause dissolucytosis of metallic silver. Histol. Histopathol. 24, 167 (2009).
10. C. Carlson, S. M. Hussain, A. M. Schrand, L. K. Braydich-Stolle, K. L. Hess, R. L. Jones, and J. J. Schlager, Unique cellular interaction of silver nanoparticles: size-dependent generation of reactive oxygen species. J. Phys. Chem. B 112, 13608 (2008).
11. F. Martinez-Gutierrez, E. P. Thi, J. M. Silverman, C. C. de Oliveira, S. L. Svensson, A. Vanden Hoek, E. M. Sanchez, N. E. Reiner, E. C. Gaynor, E. L. Pryzdial, E. M. Conway, E. Orrantia, F. Ruiz, Y. Av-Gay, and H. Bach, Antibacterial activity, inflammatory response, coagulation and cytotoxicity effects of silver nanoparticles. Nanomedicine. 8, 328 (2012).
12. A. L. Guildford, T. Poletti, L. H. Osbourne, A. Di Cerbo, A. M. Gatti, and M. Santin, Nanoparticles of a different source induce different patterns of activation in key biochemical and cellular components of the host response. J. R. Soc. Interface 6, 1213 (2009).
13. J. Park, D. H. Lim, H. J. Lim, T. Kwon, J. S. Choi, S. Jeong, I. H. Choi, and J. Cheon, Size dependent macrophage responses and toxicological effects of Ag nanoparticles. Chem. Commun. (Camb.) 47, 4382 (2011).
14. S. Bruns, O. Kniemeyer, M. Hasenberg, V. Aimanianda, S. Nietzsche, A. Thywissen, A. Jeron, J. P. Latge, A. A. Brakhage, and M. Gunzer, Production of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodA. PLoS. Pathog. 6, e1000873 (2010).
15. G. Danscher and L. J. Locht, In vivo liberation of silver ions from metallic silver surfaces. Histochem. Cell Biol. 133, 359 (2010).
16. H. Haase, S. Hebel, G. Engelhardt, and L. Rink, Flow cytometric measurement of labile zinc in peripheral blood mononuclear cells. Anal. Biochem. 352, 222 (2006).
17. H. Haase, J. L. Ober-Blobaum, G. Engelhardt, S. Hebel, A. Heit, H. Heine, and L. Rink, Zinc signals are essential for lipopolysaccharide-induced signal transduction in monocytes. J. Immunol. 181, 6491 (2008).
18. C. A. Schneider, W. S. Rasband, and K. W. Eliceiri, NIH Image to ImageJ: 25 years of image analysis. Nat. Methods 9, 671 (2012).
19. R. Hasan, L. Rink, and H. Haase, Zinc signals in neutrophil granulocytes are required for the formation of neutrophil extracellular traps. Innate. Immun. 19, 253 (2013).
20. M. M. Cortese-Krott, M. Munchow, E. Pirev, F. Hessner, A. Bozkurt, P. Uciechowski, N. Pallua, K. D. Kroncke, and C. V. Suschek, Silver ions induce oxidative stress and intracellular zinc release in human skin fibroblasts. Free Radic. Biol. Med. 47, 1570 (2009).
21. M. J. Kaplan and M. Radic, Neutrophil extracellular traps: Double-edged swords of innate immunity. J. Immunol. 189, 2689 (2012).
22. A. M. Scheuhammer and M. G. Cherian, Quantification of metal-lothioneins by a silver-saturation method. Toxicol. Appl. Pharmacol. 82, 417 (1986).
23. H. Haase and L. Rink, Functional significance of zinc-related signaling pathways in immune cells. Annu. Rev. Nutr. 29, 133 (2009).
24. J. M. Samet and T. L. Tal, Toxicological disruption of signaling homeostasis: Tyrosine phosphatases as targets. Annu. Rev. Pharmacol. Toxicol. 50, 215 (2010).
25. H. Haase and W. Maret, Intracellular zinc fluctuations modulate protein tyrosine phosphatase activity in insulin/insulin-like growth factor-1 signaling. Exp. Cell Res. 291, 289 (2003).
26. G. Anderegg, E. Hubmann, N. G. Podder, and F. Wenk, Die Thermo-dynamik der Metallkomplexbildung mit Bis-, Tris- und Tetrakis[2-pyridyl)methyl]-aminen. Helv. Chim. Acta 60, 123 (1977).
27. H. Haase, J. L. Ober-Blobaum, G. Engelhardt, S. Hebel, and L. Rink, Cadmium ions induce monocytic production of tumor necrosis factor-alpha by inhibiting mitogen activated protein kinase dephosphorylation. Toxicol. Lett. 198, 152 (2010).
28. S. Takashiba, T. E. Van Dyke, L. Shapira, and S. Amar, Lipopolysaccharide-inducible and salicylate-sensitive nuclear factor(s) on human tumor necrosis factor alpha promoter. Infect. Immun. 63, 1529 (1995).