Human experimental pain models for assessing the therapeutic efficacy of analgesic drugs

Pharmacological Reviews

Volumn 64, Issue 3, 2012, Pages 722-779

  Olesen, Anne Estrup ^a   Andresen, Trine ^a   Staahl, Camilla ^b   Drewes, Asbjørn Mohr ^a,c  

^a AALBORG UNIVERSITY HOSPITAL   (Denmark)

^b GRÜNENTHAL GMBH   (Germany)

^c AALBORG UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALFENTANIL; ALOSETRON; AMITRIPTYLINE; ANALGESIC AGENT; ASIMADOLINE; DELTA9(11) TETRAHYDROCANNABINOL; DEXTROMETHORPHAN; DICLOFENAC; FEDOTOZINE; FENTANYL; FLUOXETINE; GABAPENTIN; GRANISETRON; IBUPROFEN; IMIPRAMINE; KETAMINE; KETOROLAC; LAMOTRIGINE; MORPHINE; NAPROXEN; ONDANSETRON; OXYCODONE; PARACETAMOL; PENTAZOCINE; PETHIDINE; PREGABALIN; REMIFENTANIL; TRAMADOL; UNINDEXED DRUG;

ALGOMETRY; ANALGESIC ACTIVITY; ARTICLE; BURN; CHRONIC PANCREATITIS; CHRONIC TENSION HEADACHE; COLD PRESSOR TEST; COLD SENSATION; CONCENTRIC MUSCLE CONTRACTION; CONTINUOUS INFUSION; DIFFUSE NOXIOUS INHIBITORY CONTROL; DRUG BLOOD LEVEL; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG HALF LIFE; DRUG TREATMENT FAILURE; ELECTROENCEPHALOGRAPHY; ELECTROSTIMULATION; ENTERITIS; EVOKED RESPONSE; FIBROMYALGIA; HEAT SENSATION; HUMAN; HYPERALGESIA; INFLAMMATORY PAIN; ISCHEMIA; LASER; LONG TERM DEPRESSION; LONG TERM POTENTIATION; LOW BACK PAIN; LOW DRUG DOSE; MAGNETOENCEPHALOGRAPHY; MCGILL PAIN QUESTIONNAIRE; MECHANICAL STIMULATION; MYALGIA; NEUROPATHIC PAIN; NOCICEPTION; NOCICEPTIVE PAIN; NOCICEPTIVE RECEPTOR; NOCICEPTIVE STIMULATION; NONCARDIAC CHEST PAIN; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOARTHRITIS; PAIN; PAIN ASSESSMENT; PAIN THRESHOLD; POSITRON EMISSION TOMOGRAPHY; POSTHERPETIC NEURALGIA; PRIORITY JOURNAL; REFERRED PAIN; SCLEROSIS; SENSITIZATION; SENSORY NERVE; SINGLE DRUG DOSE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SKIN TINGLING; SPATIAL SUMMATION; SYNAPTOSOME; TEMPORAL SUMMATION; THERMAL STIMULATION; TOOTH PAIN; TOUCH; VISCERAL PAIN; VISUAL ANALOG SCALE; WITHDRAWAL REFLEX;

ANALGESICS; ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; HYPERALGESIA; NONTHERAPEUTIC HUMAN EXPERIMENTATION; PAIN MEASUREMENT; PAIN THRESHOLD; SPECIES SPECIFICITY;

EID: 84930478017     PISSN: 00316997     EISSN: 15210081     Source Type: Journal    
DOI: 10.1124/pr.111.005447     Document Type: Article

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