Hyperalgesia induced by cutaneous freeze injury for testing analgesics in healthy volunteers

British Journal of Clinical Pharmacology

Volumn 61, Issue 4, 2006, Pages 389-397

  Chassaing, Claude ^a,b,d   Schmidt, Jeannot ^b,c   Eschalier, Alain ^a,b,c   Cardot, Jean Michel ^b   Dubray, Claude ^a,b,c  

^a INSERM   (France)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

^c SERVICE DE RHUMATOLOGIE   (France)

^d Faculté de Médecine   (France)

Author keywords

Analgesics; Clinical pharmacology; Human pain models; Hyperalgesia; Nonsteroidal anti inflammatory drugs

Indexed keywords

ANALGESIC AGENT; GELUFENE; GELUPRANE; IBUPROFEN; PARACETAMOL; PLACEBO;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG ADMINISTRATION ROUTE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SCREENING; FREEZING; HUMAN; HYPERALGESIA; MALE; NORMAL HUMAN; PAIN ASSESSMENT; PAIN THRESHOLD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SKIN INJURY;

ACETAMINOPHEN; ADMINISTRATION, ORAL; ADMINISTRATION, TOPICAL; ADULT; ANALGESICS, NON-NARCOTIC; AREA UNDER CURVE; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FREEZING; HUMANS; HYPERALGESIA; IBUPROFEN; MODELS, BIOLOGICAL; PAIN MEASUREMENT; SKIN;

EID: 33645025625     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2006.02582.x     Document Type: Article

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