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Volumn 7, Issue 1, 2007, Pages 26-41

Unraveling the story of NGF-mediated sensitization of nociceptive sensory neurons: On or off the trks?

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN RECEPTOR; PROTEIN P75; PROTEIN TYROSINE KINASE A;

EID: 33847618699     PISSN: 15340384     EISSN: 15432548     Source Type: Journal    
DOI: 10.1124/mi.7.1.6     Document Type: Review
Times cited : (128)

References (176)
  • 2
    • 0025878388 scopus 로고
    • Requirement for nerve growth factor in the development of myelinated nociceptors in vivo
    • Ritter, A.M., Lewin, G.R., Kremer, N.E., Mendell, L.M. Requirement for nerve growth factor in the development of myelinated nociceptors in vivo. Nature 350, 500-502 (1991).
    • (1991) Nature , vol.350 , pp. 500-502
    • Ritter, A.M.1    Lewin, G.R.2    Kremer, N.E.3    Mendell, L.M.4
  • 3
    • 0004129725 scopus 로고
    • Biological importance of the retrograde axonal transport of nerve growth factor in sensory neurons
    • Goedert, M., Stoeckel, K., and Otten, U. Biological importance of the retrograde axonal transport of nerve growth factor in sensory neurons. Proc. Natl. Acad. Sci. USA 78, 5895-5898 (1981).
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 5895-5898
    • Goedert, M.1    Stoeckel, K.2    Otten, U.3
  • 4
    • 0037899137 scopus 로고    scopus 로고
    • NGF signaling in sensory neurons: Evidence that early endosomes carry NGF retrograde signals
    • Jul 3;, 2003
    • Delcroix, J.D., Valletta, J.S., Wu, C., Hunt, S.J., Kowal, A.S., and Mobley, W.C. NGF signaling in sensory neurons: Evidence that early endosomes carry NGF retrograde signals. Neuron Jul 3; 39, 69-84 (2003).
    • Neuron , vol.39 , pp. 69-84
    • Delcroix, J.D.1    Valletta, J.S.2    Wu, C.3    Hunt, S.J.4    Kowal, A.S.5    Mobley, W.C.6
  • 5
    • 0028297308 scopus 로고
    • Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons
    • Crowley, C., Spencer, S.D., Nishimura, M.C. et al. Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. Cell 76, 1001-1011 (1994).
    • (1994) Cell , vol.76 , pp. 1001-1011
    • Crowley, C.1    Spencer, S.D.2    Nishimura, M.C.3
  • 6
    • 0028331599 scopus 로고
    • Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene
    • Smeyne, R.J., Klein, R., Schnapp, A., Long, L.K., Bryant, S., Lewin, A. Lira, S.A., and Barbacid, M. Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene. Nature 368, 246-249 (1994).
    • (1994) Nature , vol.368 , pp. 246-249
    • Smeyne, R.J.1    Klein, R.2    Schnapp, A.3    Long, L.K.4    Bryant, S.5    Lewin, A.6    Lira, S.A.7    Barbacid, M.8
  • 7
    • 0035205827 scopus 로고    scopus 로고
    • Molecular basis of congenital insensitivity to pain with anhidrosis (CIPA): Mutations and polymorphisms in TRKA (NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor
    • Indo, Y. Molecular basis of congenital insensitivity to pain with anhidrosis (CIPA): mutations and polymorphisms in TRKA (NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor. Hum. Mutat. 18, 462-471 (2001).
    • (2001) Hum. Mutat , vol.18 , pp. 462-471
    • Indo, Y.1
  • 8
    • 0023684176 scopus 로고
    • Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons
    • Lindsay, R.M. Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons. J. Neurosci. 8, 2394-2405 (1988).
    • (1988) J. Neurosci , vol.8 , pp. 2394-2405
    • Lindsay, R.M.1
  • 9
    • 0026560958 scopus 로고
    • Endogenous NGF and nerve impulses regulate the collateral sprouting of sensory axons in the skin of the adult rat
    • Diamond, J., Holmes, M., and Coughlin, M. Endogenous NGF and nerve impulses regulate the collateral sprouting of sensory axons in the skin of the adult rat. J. Neurosci. 12, 1454-1466 (1992).
    • (1992) J. Neurosci , vol.12 , pp. 1454-1466
    • Diamond, J.1    Holmes, M.2    Coughlin, M.3
  • 10
    • 0026559892 scopus 로고
    • Sensory nerves in adult rats regenerate and restore sensory function to the skin independently of endogenous NGF
    • Diamond, J., Foerster, A., Holmes, M., and Coughlin, M. Sensory nerves in adult rats regenerate and restore sensory function to the skin independently of endogenous NGF. J. Neurosci. 12, 1467-1476 (1992).
    • (1992) J. Neurosci , vol.12 , pp. 1467-1476
    • Diamond, J.1    Foerster, A.2    Holmes, M.3    Coughlin, M.4
  • 11
    • 0030296428 scopus 로고    scopus 로고
    • Levi-Montalcini, R. and Skaper, S.D., Dal Toso, R., Petrelli, L., Leon, A. Nerve growth factor: From neurotrophin to neurokine. Trends Neurosci. 19, 514-520 (1996).
    • Levi-Montalcini, R. and Skaper, S.D., Dal Toso, R., Petrelli, L., Leon, A. Nerve growth factor: From neurotrophin to neurokine. Trends Neurosci. 19, 514-520 (1996).
  • 12
    • 33748375335 scopus 로고    scopus 로고
    • Neurotrophins: Mediators and modulators of pain
    • Pezet, S. and McMahon, S.B. Neurotrophins: Mediators and modulators of pain. Annu. Rev. Neurosci. 29, 507-538 (2006).
    • (2006) Annu. Rev. Neurosci , vol.29 , pp. 507-538
    • Pezet, S.1    McMahon, S.B.2
  • 14
    • 0026586644 scopus 로고
    • Peripheral and central mechanisms of cutaneous hyperalgesia
    • Treede, R.D., Meyer, R.A., Raja, S.N., and Campbell, J.N. Peripheral and central mechanisms of cutaneous hyperalgesia. Prog. Neurobiol. 38, 397-421 (1992).
    • (1992) Prog. Neurobiol , vol.38 , pp. 397-421
    • Treede, R.D.1    Meyer, R.A.2    Raja, S.N.3    Campbell, J.N.4
  • 15
    • 0021014399 scopus 로고
    • Evidence for a central component of post-injury pain hypersensitivity
    • Woolf, C.J. Evidence for a central component of post-injury pain hypersensitivity. Nature 306, 686-688 (1983).
    • (1983) Nature , vol.306 , pp. 686-688
    • Woolf, C.J.1
  • 16
    • 0037794324 scopus 로고    scopus 로고
    • Neurotrophic factors as novel therapeutics for neuropathic pain
    • Sah, D.W.Y., Ossipov, M.H., and Porreca, F. Neurotrophic factors as novel therapeutics for neuropathic pain. Nature Rev. 2, 460-472 (2003).
    • (2003) Nature Rev , vol.2 , pp. 460-472
    • Sah, D.W.Y.1    Ossipov, M.H.2    Porreca, F.3
  • 19
  • 20
    • 0037823440 scopus 로고    scopus 로고
    • Injection of nerve growth factor into human masseter muscle evokes long-lasting mechanical allodynia and hyperalgesia
    • Svensson, P., Cairns, B.E., Wang, K., and Arendt-Nielsen, L. Injection of nerve growth factor into human masseter muscle evokes long-lasting mechanical allodynia and hyperalgesia. Pain 104, 241-247 (2003).
    • (2003) Pain , vol.104 , pp. 241-247
    • Svensson, P.1    Cairns, B.E.2    Wang, K.3    Arendt-Nielsen, L.4
  • 21
    • 0028584437 scopus 로고
    • Peripheral and central mechanisms of NGF-induced hyperalgesia
    • Lewin, G.R., Rueff, A., and Mendell, L.M. Peripheral and central mechanisms of NGF-induced hyperalgesia. Eur. J. Neurosci. 6, 1903-1912 (1994).
    • (1994) Eur. J. Neurosci , vol.6 , pp. 1903-1912
    • Lewin, G.R.1    Rueff, A.2    Mendell, L.M.3
  • 22
    • 0028023450 scopus 로고
    • Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity
    • Woolf, C.J., Safieh-Garabedian, B., Ma, Q.P., Crilly, P., and Winter, J. Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity. Neuroscience 62, 327-331 (1994).
    • (1994) Neuroscience , vol.62 , pp. 327-331
    • Woolf, C.J.1    Safieh-Garabedian, B.2    Ma, Q.P.3    Crilly, P.4    Winter, J.5
  • 23
    • 14844303420 scopus 로고
    • Immune and glial cell factors as pain mediators and modulators
    • McMahon, S.B., Cafferty, W.B., and Marchand, F. Immune and glial cell factors as pain mediators and modulators. Exp. Neurol. 192, 444-462 (1995).
    • (1995) Exp. Neurol , vol.192 , pp. 444-462
    • McMahon, S.B.1    Cafferty, W.B.2    Marchand, F.3
  • 24
    • 0027195615 scopus 로고
    • The neurotrophic factor concept: A reexamination
    • Korsching, S. The neurotrophic factor concept: A reexamination. J. Neurosci. 13, 2739-2748 (1993).
    • (1993) J. Neurosci , vol.13 , pp. 2739-2748
    • Korsching, S.1
  • 25
    • 0030605484 scopus 로고    scopus 로고
    • NGF as a mediator of inflammatory pain
    • McMahon, S.B. NGF as a mediator of inflammatory pain. Phil. Trans. R. Soc. B. 351, 431-440 (1996).
    • (1996) Phil. Trans. R. Soc. B , vol.351 , pp. 431-440
    • McMahon, S.B.1
  • 26
    • 0034913804 scopus 로고    scopus 로고
    • Molecular interactions between neurotrophin receptors
    • Dechant, G. Molecular interactions between neurotrophin receptors. Cell Tissue Res. 305, 229-238 (2001).
    • (2001) Cell Tissue Res , vol.305 , pp. 229-238
    • Dechant, G.1
  • 27
    • 0034044227 scopus 로고    scopus 로고
    • Neurotrophin signal transduction in the nervous system
    • Kaplan, D.R. and Miller, F.D. Neurotrophin signal transduction in the nervous system. Curr. Opin. Neurobiol. 10, 381-91 (2000).
    • (2000) Curr. Opin. Neurobiol , vol.10 , pp. 381-391
    • Kaplan, D.R.1    Miller, F.D.2
  • 28
    • 0036344505 scopus 로고    scopus 로고
    • Neurotrophin signaling through the p75 neurotrophin receptor
    • Roux, P.P. and Barker, P.A. Neurotrophin signaling through the p75 neurotrophin receptor. Prog. Neurobiol. 67, 203-233 (2002).
    • (2002) Prog. Neurobiol , vol.67 , pp. 203-233
    • Roux, P.P.1    Barker, P.A.2
  • 29
    • 0037762690 scopus 로고    scopus 로고
    • Neurotrophins and their receptors: A convergence point for many signaling pathways
    • Chao, M.V. Neurotrophins and their receptors: A convergence point for many signaling pathways. Nat. Rev. Neurosci. 4, 299-309 (2003).
    • (2003) Nat. Rev. Neurosci , vol.4 , pp. 299-309
    • Chao, M.V.1
  • 30
    • 0041488911 scopus 로고    scopus 로고
    • Trk receptors: Roles in neuronal signal transduction
    • Huang, E.J. and Reichardt, L.F. Trk receptors: Roles in neuronal signal transduction. Annu. Rev. Biochem. 72, 609-642 (2003).
    • (2003) Annu. Rev. Biochem , vol.72 , pp. 609-642
    • Huang, E.J.1    Reichardt, L.F.2
  • 31
    • 33749010358 scopus 로고    scopus 로고
    • Neurotrophin-regulated signaling pathways
    • Reichardt, L.F. Neurotrophin-regulated signaling pathways. Phil. Trans. R. Soc. B., 361, 1545-1564 (2006).
    • (2006) Phil. Trans. R. Soc. B , vol.361 , pp. 1545-1564
    • Reichardt, L.F.1
  • 32
    • 0023219442 scopus 로고
    • An enzyme-linked immunoassay for nerve growth factor (NGF): A tool for studying regulatory mechanisms involved in NGF production in brain and in peripheral tissues
    • Weskamp, G. and Otten, U. An enzyme-linked immunoassay for nerve growth factor (NGF): A tool for studying regulatory mechanisms involved in NGF production in brain and in peripheral tissues. J. Neurochem. 48, 1779-1786 1987.
    • (1987) J. Neurochem , vol.48 , pp. 1779-1786
    • Weskamp, G.1    Otten, U.2
  • 33
    • 0031684386 scopus 로고    scopus 로고
    • Braun, A., Appel, E., Baruch, R., Herz, U., Botchkarev, V., Paul, R., Brodie, C., and Renz, H. Role of nerve growth factor in a mouse model of allergic airway inflammation and asthma. Eur. J. Immunol. 28, 3240-3251 (1998).
    • Braun, A., Appel, E., Baruch, R., Herz, U., Botchkarev, V., Paul, R., Brodie, C., and Renz, H. Role of nerve growth factor in a mouse model of allergic airway inflammation and asthma. Eur. J. Immunol. 28, 3240-3251 (1998).
  • 37
    • 0031955175 scopus 로고    scopus 로고
    • Psoriatic keratinocytes express high levels of nerve growth factor
    • Raychaudhuri, S.P., Jiang, W.Y., and Farber, E.M. Psoriatic keratinocytes express high levels of nerve growth factor. Acta Derm. Venereol. 78, 84-86 (1998).
    • (1998) Acta Derm. Venereol , vol.78 , pp. 84-86
    • Raychaudhuri, S.P.1    Jiang, W.Y.2    Farber, E.M.3
  • 38
    • 0026579864 scopus 로고
    • Nerve growth factor in the synovial fluid of patients with chronic arthritis
    • Aloe, L., Tuveri, M.A., Carcassi, U., and Levi-Montalcini, R. Nerve growth factor in the synovial fluid of patients with chronic arthritis. Arthritis Rheum. 35, 351-355 (1992).
    • (1992) Arthritis Rheum , vol.35 , pp. 351-355
    • Aloe, L.1    Tuveri, M.A.2    Carcassi, U.3    Levi-Montalcini, R.4
  • 39
    • 0031956503 scopus 로고    scopus 로고
    • Elevated nerve growth factor levels in the synovial fluid of patients with inflammatory joint disease
    • Halliday, D.A., Zettler, C., Rush, R.A., Scicchitano, R., and McNeil, J.D. Elevated nerve growth factor levels in the synovial fluid of patients with inflammatory joint disease. Neurochem. Res. 23, 919-922 (2004).
    • (2004) Neurochem. Res , vol.23 , pp. 919-922
    • Halliday, D.A.1    Zettler, C.2    Rush, R.A.3    Scicchitano, R.4    McNeil, J.D.5
  • 40
    • 0027406813 scopus 로고
    • Nerve growth factor-induced hyperalgesia in the neonatal and adult rat
    • Lewin, G.R., Ritter, A.M., and Mendell, L.M. Nerve growth factor-induced hyperalgesia in the neonatal and adult rat. J. Neurosci. 13, 2136-2148 (1993).
    • (1993) J. Neurosci , vol.13 , pp. 2136-2148
    • Lewin, G.R.1    Ritter, A.M.2    Mendell, L.M.3
  • 42
    • 0029925173 scopus 로고
    • Intraplantar injection of nerve growth factor into the rat hind paw: Local edema and effects on thermal nociceptive threshold
    • Amann, R., Schuligoi, R., Herzeg, G., and Donnerer, J. Intraplantar injection of nerve growth factor into the rat hind paw: Local edema and effects on thermal nociceptive threshold. PainPain 64, 323-329 (1995).
    • (1995) PainPain , vol.64 , pp. 323-329
    • Amann, R.1    Schuligoi, R.2    Herzeg, G.3    Donnerer, J.4
  • 43
    • 0027381517 scopus 로고
    • Altered expression of nerve growth factor in the skin of transgenic mice leads to changes in response to mechanical stimuli
    • Davis, B.M., Lewin, G.R., Mendell, L.M., Jones, M.E., and Albers, K.M. Altered expression of nerve growth factor in the skin of transgenic mice leads to changes in response to mechanical stimuli. Neuroscience 56, 789-792 (1993).
    • (1993) Neuroscience , vol.56 , pp. 789-792
    • Davis, B.M.1    Lewin, G.R.2    Mendell, L.M.3    Jones, M.E.4    Albers, K.M.5
  • 44
    • 0029861749 scopus 로고    scopus 로고
    • Nerve growth factor NT-5 induce increased thermal sensitivity of cutaneous nociceptors in vitro
    • Rueff, A. and Mendell, L.M. Nerve growth factor NT-5 induce increased thermal sensitivity of cutaneous nociceptors in vitro. J. Neurophysiol. 76, 3593-3596 (1996).
    • (1996) J. Neurophysiol , vol.76 , pp. 3593-3596
    • Rueff, A.1    Mendell, L.M.2
  • 45
    • 0030200824 scopus 로고    scopus 로고
    • Sensitization of visceral afferents by nerve growth factor in the adult rat
    • Dmitrieva, N and McMahon, S.B. Sensitization of visceral afferents by nerve growth factor in the adult rat. Pain 66, 87-97 (1996).
    • (1996) Pain , vol.66 , pp. 87-97
    • Dmitrieva, N.1    McMahon, S.B.2
  • 46
    • 0026077316 scopus 로고
    • Differential effects on sensory nerve processes and behavioral alterations in the rat after treatment with antibodies to nerve growth factor
    • Urschel, B.A., Brown, P.N., and Hulsebosch, C.E. Differential effects on sensory nerve processes and behavioral alterations in the rat after treatment with antibodies to nerve growth factor. Exp. Neurol. 114, 44-52 (1991).
    • (1991) Exp. Neurol , vol.114 , pp. 44-52
    • Urschel, B.A.1    Brown, P.N.2    Hulsebosch, C.E.3
  • 47
    • 0029085192 scopus 로고
    • The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule
    • McMahon, S.B., Bennett, D.L., Priestley, J.V., and Shelton, D.L. The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule. Nat. Med. 1, 774-780 (1995).
    • (1995) Nat. Med , vol.1 , pp. 774-780
    • McMahon, S.B.1    Bennett, D.L.2    Priestley, J.V.3    Shelton, D.L.4
  • 48
    • 0032906125 scopus 로고    scopus 로고
    • Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin
    • Koltzenburg, M., Bennett, D.L., Shelton, D.L., and McMahon, S.B. Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin. Eur. J. Neurosci. 11, 1698-1704 (1999).
    • (1999) Eur. J. Neurosci , vol.11 , pp. 1698-1704
    • Koltzenburg, M.1    Bennett, D.L.2    Shelton, D.L.3    McMahon, S.B.4
  • 49
    • 0035890157 scopus 로고    scopus 로고
    • Time course and nerve growth factor dependence of inflammation-induced alterations in electrophysiological membrane properties in nociceptive primary afferent neurons
    • Djouhri, L., Dawbard, D., Robertson, A., Newton, R., and Lawson, S.N. Time course and nerve growth factor dependence of inflammation-induced alterations in electrophysiological membrane properties in nociceptive primary afferent neurons. J. Neurosci. 21, 8722-8733 (2001).
    • (2001) J. Neurosci , vol.21 , pp. 8722-8733
    • Djouhri, L.1    Dawbard, D.2    Robertson, A.3    Newton, R.4    Lawson, S.N.5
  • 52
    • 0007350450 scopus 로고
    • Nerve growth factor stimulates the development of substance P in sensory ganglia
    • Kessler, J.A. and Black, I.B. Nerve growth factor stimulates the development of substance P in sensory ganglia. Proc. Natl. Acad. Sci. USA 77 649-652 (1980).
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 649-652
    • Kessler, J.A.1    Black, I.B.2
  • 53
    • 0019195743 scopus 로고
    • Requirement of nerve growth factor for development of substance P-containing sensory neurons
    • Otten, U., Goedert, M., Mayer, N., and Lembeck, F. Requirement of nerve growth factor for development of substance P-containing sensory neurons. Nature 287, 158-159 (1980).
    • (1980) Nature , vol.287 , pp. 158-159
    • Otten, U.1    Goedert, M.2    Mayer, N.3    Lembeck, F.4
  • 54
    • 0024503489 scopus 로고
    • Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons
    • Lindsay, R.M. and Harmar, A.J. Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons. Nature 337, 362-364 (1989).
    • (1989) Nature , vol.337 , pp. 362-364
    • Lindsay, R.M.1    Harmar, A.J.2
  • 55
    • 0024817088 scopus 로고
    • Neuropeptide expression in cultures of adult sensory neurons: Modulation of substance P and calcitonin gene-related peptide levels by nerve growth factor
    • Lindsay, R.M., Lockett, C., Sternberg, J., and Winter, J. Neuropeptide expression in cultures of adult sensory neurons: Modulation of substance P and calcitonin gene-related peptide levels by nerve growth factor. Neuroscience 33, 53-65 (1989).
    • (1989) Neuroscience , vol.33 , pp. 53-65
    • Lindsay, R.M.1    Lockett, C.2    Sternberg, J.3    Winter, J.4
  • 56
    • 0028344775 scopus 로고
    • Neuropeptide expression by newborn and adult rat sensory neurons in culture: Effects of nerve growth factor and other neurotrophic factors
    • Mulderry, P.K. Neuropeptide expression by newborn and adult rat sensory neurons in culture: Effects of nerve growth factor and other neurotrophic factors. Neuroscience 59, 673-688 (1994).
    • (1994) Neuroscience , vol.59 , pp. 673-688
    • Mulderry, P.K.1
  • 57
    • 0033959466 scopus 로고    scopus 로고
    • Intrathecally injected neurotrophins and the release of substance P from the rat isolated spinal cord
    • Malcangio, M., Ramer, M.S., Boucher, T.J., and McMahon, S.B. Intrathecally injected neurotrophins and the release of substance P from the rat isolated spinal cord. Eur. J. Neurosci. 12, 139-144 (2000).
    • (2000) Eur. J. Neurosci , vol.12 , pp. 139-144
    • Malcangio, M.1    Ramer, M.S.2    Boucher, T.J.3    McMahon, S.B.4
  • 58
    • 33745893566 scopus 로고    scopus 로고
    • Chronic nerve growth factor administration increases the peripheral exocytotic activity of capsaicin-sensitive cutaneous neurons
    • Bowles, W.R., Sabino, M., Harding-Rose, C., and Hargreaves, K.M. Chronic nerve growth factor administration increases the peripheral exocytotic activity of capsaicin-sensitive cutaneous neurons. Neurosci. Lett. 403, 305-308 (2006).
    • (2006) Neurosci. Lett , vol.403 , pp. 305-308
    • Bowles, W.R.1    Sabino, M.2    Harding-Rose, C.3    Hargreaves, K.M.4
  • 59
    • 0026631031 scopus 로고
    • Increased content and transport of substance P and calcitonin gene-related peptide in sensory nerves innervating inflamed tissue: Evidence for a regulatory function of nerve growth factor in vivo
    • Donnerer, J., Schuligoi, R., and Stein, C. Increased content and transport of substance P and calcitonin gene-related peptide in sensory nerves innervating inflamed tissue: Evidence for a regulatory function of nerve growth factor in vivo. Neuroscience 49, 693-698 (1992).
    • (1992) Neuroscience , vol.49 , pp. 693-698
    • Donnerer, J.1    Schuligoi, R.2    Stein, C.3
  • 60
    • 0028969303 scopus 로고
    • Plasticity in the synthesis and storage of substance P and calcitonin gene-related peptide in primary afferent neurons during peripheral inflammation
    • Galeazza, M.T., Garry, M.G., Yost, H.J., Strait, K.A., Hargreaves, K.M., and Seybold, V.S. Plasticity in the synthesis and storage of substance P and calcitonin gene-related peptide in primary afferent neurons during peripheral inflammation. Neuroscience 66,443-458 (1995).
    • (1995) Neuroscience , vol.66 , pp. 443-458
    • Galeazza, M.T.1    Garry, M.G.2    Yost, H.J.3    Strait, K.A.4    Hargreaves, K.M.5    Seybold, V.S.6
  • 61
    • 0026637909 scopus 로고
    • Enhanced release of immunoreactive CGRP and substance P from spinal cord slices occurs during carrageenan inflammation
    • Garry, M.G. and Hargreaves, K.M. Enhanced release of immunoreactive CGRP and substance P from spinal cord slices occurs during carrageenan inflammation. Brain Res. 582, 139-142 (1992)
    • (1992) Brain Res , vol.582 , pp. 139-142
    • Garry, M.G.1    Hargreaves, K.M.2
  • 62
    • 0032189516 scopus 로고    scopus 로고
    • Intrathecal NSAIDS attenuate inflammation-induced neuropeptide release from rat spinal cord slices
    • Southall, M.D., Michael, R.L., and Vasko, M.R. Intrathecal NSAIDS attenuate inflammation-induced neuropeptide release from rat spinal cord slices. Pain 78, 39-48 (1998).
    • (1998) Pain , vol.78 , pp. 39-48
    • Southall, M.D.1    Michael, R.L.2    Vasko, M.R.3
  • 63
    • 0024151369 scopus 로고
    • Nerve growth factor (NGF) regulates adult rat cultured dorsal root ganglion neuron responses to the excitotoxin capsaicin
    • Winter, J., Forbes, C.A., Sternberb, J., and Lindsay, R.M. Nerve growth factor (NGF) regulates adult rat cultured dorsal root ganglion neuron responses to the excitotoxin capsaicin. Neuron 1, 973-981 (1988).
    • (1988) Neuron , vol.1 , pp. 973-981
    • Winter, J.1    Forbes, C.A.2    Sternberb, J.3    Lindsay, R.M.4
  • 64
    • 0026595244 scopus 로고
    • Effects of nerve growth factor on TTX- and capsaicin-sensitivity in adult rat sensory neurons
    • Aguayo, L.G. and White, G. Effects of nerve growth factor on TTX- and capsaicin-sensitivity in adult rat sensory neurons. Brain Res. 570, 61-67 (1992).
    • (1992) Brain Res , vol.570 , pp. 61-67
    • Aguayo, L.G.1    White, G.2
  • 65
    • 0029034823 scopus 로고
    • Nerve growth factor (NGF) differentially regulates the chemosensitivity of adult rat cultured sensory neurons
    • Bevan, S. and Winter, J. Nerve growth factor (NGF) differentially regulates the chemosensitivity of adult rat cultured sensory neurons. J. Neurosci. 15, 4918-4926 (1995).
    • (1995) J. Neurosci , vol.15 , pp. 4918-4926
    • Bevan, S.1    Winter, J.2
  • 66
    • 0035125534 scopus 로고    scopus 로고
    • Nerve growth factor regulates VR-1 mRNA levels in cultures of adult dorsal root ganglion neurons
    • Winston, J., Toma, H., Shenoy, M., and Pasricha, P.J. Nerve growth factor regulates VR-1 mRNA levels in cultures of adult dorsal root ganglion neurons. Pain 89, 181-186 (2001).
    • (2001) Pain , vol.89 , pp. 181-186
    • Winston, J.1    Toma, H.2    Shenoy, M.3    Pasricha, P.J.4
  • 67
    • 0037282830 scopus 로고    scopus 로고
    • Activation of Ras is necessary and sufficient for upregulation of vanilloid receptor type 1 in sensory neurons by neurotrophic factors
    • Bron, R., Klesse, L.J., Shah, K., Parada, L.F., and Winter, J. Activation of Ras is necessary and sufficient for upregulation of vanilloid receptor type 1 in sensory neurons by neurotrophic factors. Mol. Cell. Neurosci. 22, 118-132 (2003).
    • (2003) Mol. Cell. Neurosci , vol.22 , pp. 118-132
    • Bron, R.1    Klesse, L.J.2    Shah, K.3    Parada, L.F.4    Winter, J.5
  • 68
    • 0037179755 scopus 로고    scopus 로고
    • p38 MAPK Activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia
    • Ji, R.-R., Samad, T.A., Jin, S.-X., Schmoll, R., and Woolf, C.J. p38 MAPK Activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia. Neuron 36, 57-68 (2002).
    • (2002) Neuron , vol.36 , pp. 57-68
    • Ji, R.-R.1    Samad, T.A.2    Jin, S.-X.3    Schmoll, R.4    Woolf, C.J.5
  • 69
    • 4644250844 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization
    • Zhuang, Z.Y., Xu, H., Clapham, D.E., and Ji, R.R. Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization. J. Neurosci. 24, 8300-8309 (2004).
    • (2004) J. Neurosci , vol.24 , pp. 8300-8309
    • Zhuang, Z.Y.1    Xu, H.2    Clapham, D.E.3    Ji, R.R.4
  • 71
    • 0033985255 scopus 로고    scopus 로고
    • Gould, H.J. III, Gould, T.N., England. J.D., Paul, D., Liu, Z.P., and Levinson, S.R. A possible role for nerve growth factor in the augmentation of sodium channels in models of chronic pain. Brain Res. 854, 19-29 (2000).
    • Gould, H.J. III, Gould, T.N., England. J.D., Paul, D., Liu, Z.P., and Levinson, S.R. A possible role for nerve growth factor in the augmentation of sodium channels in models of chronic pain. Brain Res. 854, 19-29 (2000).
  • 72
    • 0032031629 scopus 로고    scopus 로고
    • Nerve growth factor regulates the expression of bradykinin binding sites on adult sensory neurons via the neurotrophin receptor p75
    • Petersen, M., von Banchet, G.S., Heppelmann, B., and Koltzenburg, M. Nerve growth factor regulates the expression of bradykinin binding sites on adult sensory neurons via the neurotrophin receptor p75. Neuroscience 83, 161-168 (1998).
    • (1998) Neuroscience , vol.83 , pp. 161-168
    • Petersen, M.1    von Banchet, G.S.2    Heppelmann, B.3    Koltzenburg, M.4
  • 74
    • 0037115054 scopus 로고    scopus 로고
    • Proinflammatory mediators, stimulators of sensory neuron excitability via the expression of acid-sensing ion channels
    • Mamet, J., Baron, A., Lazdunski, M., and Voilley, N. Proinflammatory mediators, stimulators of sensory neuron excitability via the expression of acid-sensing ion channels. J. Neurosci. 22, 10662-10670 (2002).
    • (2002) J. Neurosci , vol.22 , pp. 10662-10670
    • Mamet, J.1    Baron, A.2    Lazdunski, M.3    Voilley, N.4
  • 75
    • 0033520187 scopus 로고    scopus 로고
    • Endogenous nerve growth factor increases the sensitivity to bradykinin in small dorsal root ganglion neurons of adjuvant inflamed rats
    • Kasai, M. and Mizumura, K. Endogenous nerve growth factor increases the sensitivity to bradykinin in small dorsal root ganglion neurons of adjuvant inflamed rats. Neurosci. Lett. 272, 41-44 (1999).
    • (1999) Neurosci. Lett , vol.272 , pp. 41-44
    • Kasai, M.1    Mizumura, K.2
  • 77
    • 0025941955 scopus 로고
    • Cell-type-specific regulation of nerve growth factor (NGF) synthesis in non-neuronal cells: Comparison of Schwann cells with other cell types
    • Matsuoka, I., Meyer, M., and Thoenen, H. Cell-type-specific regulation of nerve growth factor (NGF) synthesis in non-neuronal cells: Comparison of Schwann cells with other cell types. J. Neurosci. 11, 3165-3177 (1991).
    • (1991) J. Neurosci , vol.11 , pp. 3165-3177
    • Matsuoka, I.1    Meyer, M.2    Thoenen, H.3
  • 78
    • 0023317628 scopus 로고
    • Cellular localization of nerve growth factor synthesis by in situ hybridization
    • Bandtlow, C.E., Heumann, R., Schwab, M.E., and Thoenen, H. Cellular localization of nerve growth factor synthesis by in situ hybridization. EMBO J. 6, 891-899 (1987).
    • (1987) EMBO J , vol.6 , pp. 891-899
    • Bandtlow, C.E.1    Heumann, R.2    Schwab, M.E.3    Thoenen, H.4
  • 79
    • 0023256354 scopus 로고
    • Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection
    • Heumann, R., Korsching, S., Bandtlow, C., and Thoenen, H. Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection. J. Cell Biol. 104, 1623-1631 (1987).
    • (1987) J. Cell Biol , vol.104 , pp. 1623-1631
    • Heumann, R.1    Korsching, S.2    Bandtlow, C.3    Thoenen, H.4
  • 81
    • 0023461564 scopus 로고
    • Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: Role of macrophages
    • Heumann, R., Lindholm, D., Bandtlow, C., Meyer, M., Radeke, M.J., Misko, T.P., Shooter, E., and Thoenen, H. Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: Role of macrophages. Proc. Natl. Acad. Sci. USA 84, 8735-8739 (1987).
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 8735-8739
    • Heumann, R.1    Lindholm, D.2    Bandtlow, C.3    Meyer, M.4    Radeke, M.J.5    Misko, T.P.6    Shooter, E.7    Thoenen, H.8
  • 82
    • 0027486268 scopus 로고
    • Nerve growth factor binds to normal human keratinocytes through high- and low-affinity receptors and stimulates their growth by a novel autocrine loop
    • DiMarco, E., Mathor, M., Bondanza, S., Cutuli, N., Marchisio, P.C., Cancedda, R., and DeLuca, M. Nerve growth factor binds to normal human keratinocytes through high- and low-affinity receptors and stimulates their growth by a novel autocrine loop. J. Biol. Chem. 268, 22838-46 (1993).
    • (1993) J. Biol. Chem , vol.268 , pp. 22838-22846
    • DiMarco, E.1    Mathor, M.2    Bondanza, S.3    Cutuli, N.4    Marchisio, P.C.5    Cancedda, R.6    DeLuca, M.7
  • 83
    • 0027265946 scopus 로고
    • Mediator release from mast cells by nerve growth factor
    • Horigome, K., Pryor, J.C., Bullock, E.D., and Johnson, E.M. Jr., Mediator release from mast cells by nerve growth factor. J. Biol. Chem. 268, 14881-14887 (1993).
    • (1993) J. Biol. Chem , vol.268 , pp. 14881-14887
    • Horigome, K.1    Pryor, J.C.2    Bullock, E.D.3    Johnson Jr., E.M.4
  • 84
    • 0030799228 scopus 로고    scopus 로고
    • Nilsson, G., Forsberg-Nilsson, K., Xiang, Z., Hallbrook, F., Nilsson, K, and Metcalfe, D.D. Human mast cells express functional TrkA and are a source of nerve growth factor. Eur. J. Immunol. 27, 2295-2301 (1997).
    • Nilsson, G., Forsberg-Nilsson, K., Xiang, Z., Hallbrook, F., Nilsson, K, and Metcalfe, D.D. Human mast cells express functional TrkA and are a source of nerve growth factor. Eur. J. Immunol. 27, 2295-2301 (1997).
  • 85
    • 0029034576 scopus 로고
    • Immunohistochemical localization of TrkA receptors in chemically identified subgroups of adult rat sensory neurons
    • Averill, S., McMahon, S.B., Clary, D.O., Reichardt, L.F., and Priestley, J.V. Immunohistochemical localization of TrkA receptors in chemically identified subgroups of adult rat sensory neurons. Eur. J. Neurosci. 7, 1484-1494 (1995).
    • (1995) Eur. J. Neurosci , vol.7 , pp. 1484-1494
    • Averill, S.1    McMahon, S.B.2    Clary, D.O.3    Reichardt, L.F.4    Priestley, J.V.5
  • 86
    • 0024368437 scopus 로고
    • Histochemical characterization of sensory neurons with high-affinity receptors for nerve growth factor
    • Verge, V.M., Richardson, P.M., Benoit, R., and Riopelle, R.J. Histochemical characterization of sensory neurons with high-affinity receptors for nerve growth factor. J. Neurocytol. 18, 583-591 (1989).
    • (1989) J. Neurocytol , vol.18 , pp. 583-591
    • Verge, V.M.1    Richardson, P.M.2    Benoit, R.3    Riopelle, R.J.4
  • 87
    • 0026784969 scopus 로고
    • Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: Responses of injury and infusion of NGF
    • Verge, V.M., Merlio, J.P., Grondin, J., Ernfors, P., Persson, H., Riopelle, R.J., Hokfelt, T., and Richardson, P.M. Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: Responses of injury and infusion of NGF. J. Neurosci. 12, 4011-4022 (1992).
    • (1992) J. Neurosci , vol.12 , pp. 4011-4022
    • Verge, V.M.1    Merlio, J.P.2    Grondin, J.3    Ernfors, P.4    Persson, H.5    Riopelle, R.J.6    Hokfelt, T.7    Richardson, P.M.8
  • 88
    • 0028936395 scopus 로고
    • Neurotrophin receptor mRNA expression defines distinct populations of neurons in rat dorsal root ganglia
    • Wright, D.E and Snider, W.D. Neurotrophin receptor mRNA expression defines distinct populations of neurons in rat dorsal root ganglia. J. Comp. Neurol. 351, 329-338 (1995).
    • (1995) J. Comp. Neurol , vol.351 , pp. 329-338
    • Wright, D.E.1    Snider, W.D.2
  • 89
    • 0343052745 scopus 로고    scopus 로고
    • Local injection of nerve growth factor (NGF) triggers degranulation of mast cells in rat paw
    • Tal, M. and Liberman, R. Local injection of nerve growth factor (NGF) triggers degranulation of mast cells in rat paw. Neurosci. Lett. 221, 129-132 (1997).
    • (1997) Neurosci. Lett , vol.221 , pp. 129-132
    • Tal, M.1    Liberman, R.2
  • 90
  • 91
    • 0029981215 scopus 로고    scopus 로고
    • Peripheral cell types contributing to the hyperalgesic action of nerve growth factor in inflammation
    • Woolf, C.J., Ma, Q.-P., Allchorne, A., and Poole, S. Peripheral cell types contributing to the hyperalgesic action of nerve growth factor in inflammation. J. Neurosci. 16, 2716-2723 (1996).
    • (1996) J. Neurosci , vol.16 , pp. 2716-2723
    • Woolf, C.J.1    Ma, Q.-P.2    Allchorne, A.3    Poole, S.4
  • 92
    • 0028824538 scopus 로고
    • Peripheral administration of nerve growth factor in the adult rat produces a thermal hyperalgesia that requires the presence of sympathetic post-ganglionic neurones
    • Andreev, N.Y., Dimitrieva, N., Koltzenburg, M., and McMahon, S.B. Peripheral administration of nerve growth factor in the adult rat produces a thermal hyperalgesia that requires the presence of sympathetic post-ganglionic neurones. Pain 63, 109-115, (1995).
    • (1995) Pain , vol.63 , pp. 109-115
    • Andreev, N.Y.1    Dimitrieva, N.2    Koltzenburg, M.3    McMahon, S.B.4
  • 93
    • 0027476372 scopus 로고
    • Tumor necrosis factor stimulates the synthesis and secretion of biologically active nerve growth factor in non-neuronal cells
    • Hattori, A., Tanaka, E., Murase, K., Ishida, N., Chatani, Y., Tsujimoto, M., Hayashi, K., and Kohno, M. Tumor necrosis factor stimulates the synthesis and secretion of biologically active nerve growth factor in non-neuronal cells. J. Biol. Chem. 268, 2577-2582 (1993).
    • (1993) J. Biol. Chem , vol.268 , pp. 2577-2582
    • Hattori, A.1    Tanaka, E.2    Murase, K.3    Ishida, N.4    Chatani, Y.5    Tsujimoto, M.6    Hayashi, K.7    Kohno, M.8
  • 94
    • 0028982492 scopus 로고
    • Contribution of interleukin-1β to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia
    • Safieh-Garabedian, B., Poole, S., Allchorne, A., Winter, J., and Woolf, C.J. Contribution of interleukin-1β to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia. Br. J. Pharmacol. 115, 1265-1275 (1995).
    • (1995) Br. J. Pharmacol , vol.115 , pp. 1265-1275
    • Safieh-Garabedian, B.1    Poole, S.2    Allchorne, A.3    Winter, J.4    Woolf, C.J.5
  • 95
    • 0030913028 scopus 로고    scopus 로고
    • Cytokines, nerve growth factor and inflammatory hyperalgesia: The contribution of tumour necrosis factor alpha
    • Woolf, C.J., Allchorne, A., Safieh-Garabedian, B., and Poole, S. Cytokines, nerve growth factor and inflammatory hyperalgesia: The contribution of tumour necrosis factor alpha. Brit. J. Pharmacol. 121, 417-424 (1997).
    • (1997) Brit. J. Pharmacol , vol.121 , pp. 417-424
    • Woolf, C.J.1    Allchorne, A.2    Safieh-Garabedian, B.3    Poole, S.4
  • 96
    • 0032849082 scopus 로고    scopus 로고
    • Nerve growth factor acutely sensitizes the response of adult rat sensory neurons to capsaicin
    • Shu, X.-Q. and Mendell, L.M. Nerve growth factor acutely sensitizes the response of adult rat sensory neurons to capsaicin. Neurosci. Lett. 274, 159-162 (1999).
    • (1999) Neurosci. Lett , vol.274 , pp. 159-162
    • Shu, X.-Q.1    Mendell, L.M.2
  • 97
    • 0035927651 scopus 로고    scopus 로고
    • 2-mediated inhibition. Nature 411, 957-962 (2001).
    • 2-mediated inhibition. Nature 411, 957-962 (2001).
  • 98
    • 0041920806 scopus 로고    scopus 로고
    • Mechanisms of sensitization of the response of single dorsal root ganglion cells from adult rat to noxious heat
    • Galoyan, S.M., Petruska, J.C., and Mendell, L.M. Mechanisms of sensitization of the response of single dorsal root ganglion cells from adult rat to noxious heat. Eur. J. Neurosci. 18, 535-541 (2003).
    • (2003) Eur. J. Neurosci , vol.18 , pp. 535-541
    • Galoyan, S.M.1    Petruska, J.C.2    Mendell, L.M.3
  • 99
    • 0141634247 scopus 로고    scopus 로고
    • Signalling pathways involved in the sensitization of mouse nociceptive neurons by nerve growth factor
    • Bonnington, J.K. and McNaughton, P.A. Signalling pathways involved in the sensitization of mouse nociceptive neurons by nerve growth factor. J. Physiol. 551, 433-446 (2003).
    • (2003) J. Physiol , vol.551 , pp. 433-446
    • Bonnington, J.K.1    McNaughton, P.A.2
  • 100
    • 0035211454 scopus 로고    scopus 로고
    • Acute sensitization by NGF of the response of small-diameter sensory neurons to capsaicin
    • Shu, X.-Q. and Mendell, L.M. Acute sensitization by NGF of the response of small-diameter sensory neurons to capsaicin. J. Neurophysiol. 86, 2931-2938 (2001).
    • (2001) J. Neurophysiol , vol.86 , pp. 2931-2938
    • Shu, X.-Q.1    Mendell, L.M.2
  • 101
    • 0037426713 scopus 로고    scopus 로고
    • Rapid effects of neurotrophic factors on calcium homeostasis in rat visceral afferent neurons
    • Lamb, K. and Bielefeldt, K. Rapid effects of neurotrophic factors on calcium homeostasis in rat visceral afferent neurons. Neurosci. Lett. 336, 9-12 (2003).
    • (2003) Neurosci. Lett , vol.336 , pp. 9-12
    • Lamb, K.1    Bielefeldt, K.2
  • 102
    • 14844303990 scopus 로고    scopus 로고
    • A developmental switch in acute sensitization of small dorsal root ganglion (DRG) neurons to capsaicin or noxious heating by NGF
    • Zhu, W., Galoyan, S.M., Petruska, J.C., Oxford, G.S., and Mendell, L.M. A developmental switch in acute sensitization of small dorsal root ganglion (DRG) neurons to capsaicin or noxious heating by NGF. J. Neurophysiol. 92, 3148-3152 (2004).
    • (2004) J. Neurophysiol , vol.92 , pp. 3148-3152
    • Zhu, W.1    Galoyan, S.M.2    Petruska, J.C.3    Oxford, G.S.4    Mendell, L.M.5
  • 103
    • 0026766860 scopus 로고
    • The nerve growth factor family of receptors
    • Meakin, S.O. and Shooter, E.M. The nerve growth factor family of receptors. Trends Neurosci. 15, 323-331 (1992).
    • (1992) Trends Neurosci , vol.15 , pp. 323-331
    • Meakin, S.O.1    Shooter, E.M.2
  • 104
    • 0029556562 scopus 로고
    • Structural and functional properties of the TRK family of neurotrophin receptors
    • Barbacid, M. Structural and functional properties of the TRK family of neurotrophin receptors. Ann. N.Y. Acad. Sci. 766, 442-458 (1995).
    • (1995) Ann. N.Y. Acad. Sci , vol.766 , pp. 442-458
    • Barbacid, M.1
  • 105
    • 0025774207 scopus 로고
    • High-affinity NGF binding requires coexpression of the trk protooncogene and the low-affinity NGF receptor
    • Hempstead, B.L., Martin-Zanca, D., Kaplan, D.R,. Parada, L.F., and Chao, M.V. High-affinity NGF binding requires coexpression of the trk protooncogene and the low-affinity NGF receptor. Nature 350, 678-683 (1991).
    • (1991) Nature , vol.350 , pp. 678-683
    • Hempstead, B.L.1    Martin-Zanca, D.2    Kaplan, D.R.3    Parada, L.F.4    Chao, M.V.5
  • 106
    • 0026747063 scopus 로고    scopus 로고
    • Lee, K.F., Li, E., Huber, L.J., Landis, S.C., Sharpe, A.H., Chao, M.V., J and aenisch, R. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell 69, 737-749 (1992).
    • Lee, K.F., Li, E., Huber, L.J., Landis, S.C., Sharpe, A.H., Chao, M.V., J and aenisch, R. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell 69, 737-749 (1992).
  • 107
    • 0027330994 scopus 로고
    • p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins
    • Davies, A.M., Lee, K.F., and Jaenisch, R. p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins. Neuron 11, 565-574 (1993).
    • (1993) Neuron , vol.11 , pp. 565-574
    • Davies, A.M.1    Lee, K.F.2    Jaenisch, R.3
  • 109
    • 0027966170 scopus 로고
    • Disruption of NGF binding to the low-affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells
    • Barker, P.A. and Shooter, E.M. Disruption of NGF binding to the low-affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells. Neuron 3, 203-215. (1994).
    • (1994) Neuron , vol.3 , pp. 203-215
    • Barker, P.A.1    Shooter, E.M.2
  • 110
    • 0037437998 scopus 로고    scopus 로고
    • Novel functional interactions between Trk kinase and p75 neurotrophin receptor in neuroblastoma cells
    • Lachyankar, M.B., Condon, P.J., Daou, M.C., De, A.K., Levine, L.B., Oberbeier, A. and Ross, A.H. Novel functional interactions between Trk kinase and p75 neurotrophin receptor in neuroblastoma cells. J. Neurosci. Res. 71, 157-172 (2003).
    • (2003) J. Neurosci. Res , vol.71 , pp. 157-172
    • Lachyankar, M.B.1    Condon, P.J.2    Daou, M.C.3    De, A.K.4    Levine, L.B.5    Oberbeier, A.6    Ross, A.H.7
  • 111
    • 1942487757 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor enhances TrkA signaling by binding to Shc and augmenting its phosphorylation
    • Epa, W.R., Markovska, K., and Barrett, G.L. The p75 neurotrophin receptor enhances TrkA signaling by binding to Shc and augmenting its phosphorylation. J. Neurochem. 89, 344-53 (2004).
    • (2004) J. Neurochem , vol.89 , pp. 344-353
    • Epa, W.R.1    Markovska, K.2    Barrett, G.L.3
  • 112
    • 33845695804 scopus 로고    scopus 로고
    • Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors
    • Wehrman, T., He, X., Raab, B., Dukipatti, A., Blau, H., and Garcia, K.C. Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors. Neuron 53, 25-38 (2007).
    • (2007) Neuron , vol.53 , pp. 25-38
    • Wehrman, T.1    He, X.2    Raab, B.3    Dukipatti, A.4    Blau, H.5    Garcia, K.C.6
  • 113
    • 1642410893 scopus 로고    scopus 로고
    • Murray, S.S., Perez, P., Lee, R., Hempstead, B.L., and Chao, M.V. A novel p75 neurotrophin receptor-related protein, NRH2, regulates nerve growth factor binding to the TrkA receptor. J. Neurosci. 24, 2742-2749 (2004).
    • Murray, S.S., Perez, P., Lee, R., Hempstead, B.L., and Chao, M.V. A novel p75 neurotrophin receptor-related protein, NRH2, regulates nerve growth factor binding to the TrkA receptor. J. Neurosci. 24, 2742-2749 (2004).
  • 114
    • 0028108788 scopus 로고
    • Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor
    • Dobrowsky, R.T., Werner, M.H., Castellino, A.M., Chao, M.V., and Hannun, Y.A. Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor. Science 265, 1596-1599 (1994).
    • (1994) Science , vol.265 , pp. 1596-1599
    • Dobrowsky, R.T.1    Werner, M.H.2    Castellino, A.M.3    Chao, M.V.4    Hannun, Y.A.5
  • 115
    • 0033373573 scopus 로고    scopus 로고
    • Advances in the signal transduction of ceramide and related sphingolipids
    • Liu, G., Kleine, L., and Hébert R.L. Advances in the signal transduction of ceramide and related sphingolipids. Crit. Rev. Clin. Lab. Sci. 36, 511-573 (1999).
    • (1999) Crit. Rev. Clin. Lab. Sci , vol.36 , pp. 511-573
    • Liu, G.1    Kleine, L.2    Hébert, R.L.3
  • 116
    • 2942754160 scopus 로고    scopus 로고
    • Sphingolipids in inflammation: Roles and implications
    • Pettus, B.J., Chalfant, C.E., and Hannun, Y.A. Sphingolipids in inflammation: Roles and implications. Curr. Mol. Med. 4, 405-418 (2004).
    • (2004) Curr. Mol. Med , vol.4 , pp. 405-418
    • Pettus, B.J.1    Chalfant, C.E.2    Hannun, Y.A.3
  • 117
    • 33746801909 scopus 로고    scopus 로고
    • Intracellular sphingosine 1-phosphate mediates the increased excitability produced by nerve growth factor in rat sensory neurons
    • Zhang, Y.-H., Vasko, M.R., and Nicol, G.D. Intracellular sphingosine 1-phosphate mediates the increased excitability produced by nerve growth factor in rat sensory neurons. J. Physiol. 575, 101-113 (2006).
    • (2006) J. Physiol , vol.575 , pp. 101-113
    • Zhang, Y.-H.1    Vasko, M.R.2    Nicol, G.D.3
  • 119
    • 0346849774 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor: Multiple interactors and numerous functions
    • Gentry, J.J., Barker, P.A., and Carter, B.D. The p75 neurotrophin receptor: Multiple interactors and numerous functions. Prog. Brain Res. 146, 25-39 (2004).
    • (2004) Prog. Brain Res , vol.146 , pp. 25-39
    • Gentry, J.J.1    Barker, P.A.2    Carter, B.D.3
  • 121
    • 33751089066 scopus 로고    scopus 로고
    • Suppression of the p75 neurotrophin receptor in uninjured sensory neurons reduces neuropathic pain after nerve injury
    • Obata, K., Katsura, H., Sakurai, J., Kobayashi, K., Yamanaka, H., Dai, Y., Fukuoka, T., and Noguchi, K. Suppression of the p75 neurotrophin receptor in uninjured sensory neurons reduces neuropathic pain after nerve injury. J. Neurosci. 26, 11974-11986 (2006).
    • (2006) J. Neurosci , vol.26 , pp. 11974-11986
    • Obata, K.1    Katsura, H.2    Sakurai, J.3    Kobayashi, K.4    Yamanaka, H.5    Dai, Y.6    Fukuoka, T.7    Noguchi, K.8
  • 122
    • 33645460235 scopus 로고    scopus 로고
    • A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: Respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance
    • Zhuang, Z.Y., Wen, Y.R., Zhang, D.R., Borsello, T., Bonny, C., Strichartz, G.R., Decosterd, I., and Ji, R.R. A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: Respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance. J. Neurosci. 26, 3551-3560 (2006).
    • (2006) J. Neurosci , vol.26 , pp. 3551-3560
    • Zhuang, Z.Y.1    Wen, Y.R.2    Zhang, D.R.3    Borsello, T.4    Bonny, C.5    Strichartz, G.R.6    Decosterd, I.7    Ji, R.R.8
  • 123
    • 0037008693 scopus 로고    scopus 로고
    • Mamidipudi, V., Li, X., and Wooten, M.W. Identification of interleukin 1 receptor-associated kinase as a conserved component in the p75-neurotrophin receptor activation of nuclear factor-kappa B. J. Biol. Chem. 277, 28010-28018 (2002).
    • Mamidipudi, V., Li, X., and Wooten, M.W. Identification of interleukin 1 receptor-associated kinase as a conserved component in the p75-neurotrophin receptor activation of nuclear factor-kappa B. J. Biol. Chem. 277, 28010-28018 (2002).
  • 124
    • 0035896518 scopus 로고    scopus 로고
    • The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor
    • Wooten, M.W., Seibenhener, M.L., Mamidipudi, V., Diaz-Meco, M.T., Barker, P.A., and Moscat, J. The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor. J. Biol. Chem. 276, 7709-7712 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 7709-7712
    • Wooten, M.W.1    Seibenhener, M.L.2    Mamidipudi, V.3    Diaz-Meco, M.T.4    Barker, P.A.5    Moscat, J.6
  • 125
    • 0032479145 scopus 로고    scopus 로고
    • RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase
    • McCarthy, J.V., Ni ,J., and Dixit, V.M. RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase. J. Biol. Chem. 273, 16968-16975 (1998).
    • (1998) J. Biol. Chem , vol.273 , pp. 16968-16975
    • McCarthy, J.V.1    Ni, J.2    Dixit, V.M.3
  • 126
    • 0035882380 scopus 로고    scopus 로고
    • A prosurvival function for the p75 receptor death domain mediated via the caspase recruitment domain receptor-interacting protein 2
    • Khursigara, G., Bertin, J., Yano, H., Moffett, H., DiStefano, P.S., and Chao, M.V. A prosurvival function for the p75 receptor death domain mediated via the caspase recruitment domain receptor-interacting protein 2. J. Neurosci. 21, 5854-5863 (2001).
    • (2001) J. Neurosci , vol.21 , pp. 5854-5863
    • Khursigara, G.1    Bertin, J.2    Yano, H.3    Moffett, H.4    DiStefano, P.S.5    Chao, M.V.6
  • 128
    • 0032809906 scopus 로고    scopus 로고
    • p75-mediated NF-kappaB activation enhances the survival response of developing sensory neurons to nerve growth factor
    • Hamanoue, M., Middleton, G., Wyatt, S., Jaffray, E., Hay, R.T., Davies, A.M. p75-mediated NF-kappaB activation enhances the survival response of developing sensory neurons to nerve growth factor. Mol. Cell Neurosci. 14, 28-40 (1999).
    • (1999) Mol. Cell Neurosci , vol.14 , pp. 28-40
    • Hamanoue, M.1    Middleton, G.2    Wyatt, S.3    Jaffray, E.4    Hay, R.T.5    Davies, A.M.6
  • 129
    • 0028988514 scopus 로고
    • Regulation of NF-kappa B activity in rat dorsal root ganglia and PC12 cells by tumour necrosis factor and nerve growth factor
    • Wood, J.N. Regulation of NF-kappa B activity in rat dorsal root ganglia and PC12 cells by tumour necrosis factor and nerve growth factor. Neurosci. Lett. 192, 41-44 (1995).
    • (1995) Neurosci. Lett , vol.192 , pp. 41-44
    • Wood, J.N.1
  • 131
    • 33845353520 scopus 로고    scopus 로고
    • Injection of nuclear factor-kappa B decoy into the sciatic nerve suppresses mechanical allodynia and thermal hyperalgesia in a rat inflammatory pain model
    • Inoue, G., Ochiai, N., Ohtori, S. et al. Injection of nuclear factor-kappa B decoy into the sciatic nerve suppresses mechanical allodynia and thermal hyperalgesia in a rat inflammatory pain model. Spine 31, 2904-2908. 2006
    • (2006) Spine , vol.31 , pp. 2904-2908
    • Inoue, G.1    Ochiai, N.2    Ohtori, S.3
  • 132
    • 0035919810 scopus 로고    scopus 로고
    • NF-kappa B decoy suppresses cytokine expression and thermal hyperalgesia in a rat neuropathic pain model
    • Sakaue, G., Shimaoka, M., Fukuoka, T. et al. NF-kappa B decoy suppresses cytokine expression and thermal hyperalgesia in a rat neuropathic pain model. Neuroreport 12, 2079-2084 (2001).
    • (2001) Neuroreport , vol.12 , pp. 2079-2084
    • Sakaue, G.1    Shimaoka, M.2    Fukuoka, T.3
  • 133
    • 0035933783 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway
    • Roux, P.P., Bhakar, A.L., Kennedy, T.E., and Barker, P.A. The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway. J. Biol. Chem. 276, 23097-23104 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 23097-23104
    • Roux, P.P.1    Bhakar, A.L.2    Kennedy, T.E.3    Barker, P.A.4
  • 134
    • 0036319594 scopus 로고    scopus 로고
    • p75 neurotrophin receptor is required for constitutive and NGF-induced survival signaling in PC12 cells and rat hippocampal neurons
    • Bui, N.T., Konig, H.G., Culmsee, C., Bauerbach, E., Poppe, M., Krieglstein, J., and Prehn, J.H. p75 neurotrophin receptor is required for constitutive and NGF-induced survival signaling in PC12 cells and rat hippocampal neurons. J. Neurochem. 81, 594-605 (2002).
    • (2002) J. Neurochem , vol.81 , pp. 594-605
    • Bui, N.T.1    Konig, H.G.2    Culmsee, C.3    Bauerbach, E.4    Poppe, M.5    Krieglstein, J.6    Prehn, J.H.7
  • 135
    • 0027156203 scopus 로고
    • Neurotrophin induced cAMP and IP3 responses in PC12 cells. Different pathways
    • Knipper, M., Beck, A., Rylett, J., and Breer, H. Neurotrophin induced cAMP and IP3 responses in PC12 cells. Different pathways. FEBS Lett. 324, 147-152 (1993).
    • (1993) FEBS Lett , vol.324 , pp. 147-152
    • Knipper, M.1    Beck, A.2    Rylett, J.3    Breer, H.4
  • 136
    • 0037447299 scopus 로고    scopus 로고
    • PKA phosphorylates the p75 receptor and regulates its localization to lipid rafts
    • Higuchi, H., Yamashita, T., Yoshikawa, H., and Tohyama, M. PKA phosphorylates the p75 receptor and regulates its localization to lipid rafts. EMBO J. 22, 1790-1800 (2003).
    • (2003) EMBO J , vol.22 , pp. 1790-1800
    • Higuchi, H.1    Yamashita, T.2    Yoshikawa, H.3    Tohyama, M.4
  • 137
    • 12344333887 scopus 로고    scopus 로고
    • PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells
    • Obara,Y., Labudda, K., Dillon, T.J., and Stork, P.J. PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells. J. Cell Sci. 1, 6085-6094 (2004).
    • (2004) J. Cell Sci , vol.1 , pp. 6085-6094
    • Obara, Y.1    Labudda, K.2    Dillon, T.J.3    Stork, P.J.4
  • 138
  • 140
    • 21544452743 scopus 로고    scopus 로고
    • Epac mediates a cAMP-to-PKC signaling in inflammatory pain: An isolectin B4(+) neuron-specific mechanism
    • Hucho, T.B., Dina, O.A., and Levine, J.D. Epac mediates a cAMP-to-PKC signaling in inflammatory pain: An isolectin B4(+) neuron-specific mechanism. J. Neurosci. 25, 6119-6126 (2005).
    • (2005) J. Neurosci , vol.25 , pp. 6119-6126
    • Hucho, T.B.1    Dina, O.A.2    Levine, J.D.3
  • 141
    • 0029023042 scopus 로고
    • Prostaglandins facilitate peptide release from rat sensory neurons by activating the adenosine 3′,5′-cyclic monophosphate transduction cascade
    • Hingtgen, C.M., Waite, K.J., and Vasko, M.R. Prostaglandins facilitate peptide release from rat sensory neurons by activating the adenosine 3′,5′-cyclic monophosphate transduction cascade. J. Neurosci. 15, 5411-5419 (1995).
    • (1995) J. Neurosci , vol.15 , pp. 5411-5419
    • Hingtgen, C.M.1    Waite, K.J.2    Vasko, M.R.3
  • 142
    • 0032529562 scopus 로고    scopus 로고
    • The cAMP transduction cascade mediates the prostaglandin E2 enhancement of the capsaicin-elicited current in rat sensory neurons: Whole-cell and single-channel studies
    • Lopshire, J.C. and Nicol, G.D. The cAMP transduction cascade mediates the prostaglandin E2 enhancement of the capsaicin-elicited current in rat sensory neurons: Whole-cell and single-channel studies. J Neurosci. 18, 6081-6092 (1998).
    • (1998) J Neurosci , vol.18 , pp. 6081-6092
    • Lopshire, J.C.1    Nicol, G.D.2
  • 143
    • 33745215639 scopus 로고    scopus 로고
    • Soluble adenylyl cyclase mediates nerve growth factor-induced activation of Rap1
    • Stessin, A.M., Zippin, J.H., Kamenetsky, M., Hess, K.C., Buck, J., and Levin, L.R. Soluble adenylyl cyclase mediates nerve growth factor-induced activation of Rap1. J. Biol. Chem. 281, 17253-17258 (2006).
    • (2006) J. Biol. Chem , vol.281 , pp. 17253-17258
    • Stessin, A.M.1    Zippin, J.H.2    Kamenetsky, M.3    Hess, K.C.4    Buck, J.5    Levin, L.R.6
  • 145
    • 0033776498 scopus 로고    scopus 로고
    • Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1
    • York, R.D., Molliver, D.C., Grewal, S.S., Stenberg, P.E., McCleskey, E.W., and Stork, P.J. Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1. Mol. Cell. Biol. 20, 8069-8083 (2000).
    • (2000) Mol. Cell. Biol , vol.20 , pp. 8069-8083
    • York, R.D.1    Molliver, D.C.2    Grewal, S.S.3    Stenberg, P.E.4    McCleskey, E.W.5    Stork, P.J.6
  • 146
    • 0036758662 scopus 로고    scopus 로고
    • Phosphorylation of extracellular signal-regulated kinase in primary afferent neurons by noxious stimuli and its involvement in peripheral sensitization
    • Dai, Y., Iwata, K., Fukuoka, T., Kondo, E., Tokunaga, A., Yamanaka, H., Tachibana, T., Liu, Y., and Noguchi, K. Phosphorylation of extracellular signal-regulated kinase in primary afferent neurons by noxious stimuli and its involvement in peripheral sensitization. J Neurosci. 22, 7737-7745 (2002).
    • (2002) J Neurosci , vol.22 , pp. 7737-7745
    • Dai, Y.1    Iwata, K.2    Fukuoka, T.3    Kondo, E.4    Tokunaga, A.5    Yamanaka, H.6    Tachibana, T.7    Liu, Y.8    Noguchi, K.9
  • 147
    • 0035449934 scopus 로고    scopus 로고
    • Nociceptor sensitization by extracellular signal-regulated kinases
    • Aley, K.O., Martin, A., McMahon, T., Mok, J., Levine, J.D., and Messing, R.O. Nociceptor sensitization by extracellular signal-regulated kinases. J. Neurosci. 21, 6933-6939 (2001).
    • (2001) J. Neurosci , vol.21 , pp. 6933-6939
    • Aley, K.O.1    Martin, A.2    McMahon, T.3    Mok, J.4    Levine, J.D.5    Messing, R.O.6
  • 148
    • 33750527107 scopus 로고    scopus 로고
    • Phosphorylation of extracellular signal-related protein kinase is required for rapid facilitation of heat-induced currents in rat dorsal root ganglion neurons
    • Firner, M., Greffrath, W., and Treede, R.D. Phosphorylation of extracellular signal-related protein kinase is required for rapid facilitation of heat-induced currents in rat dorsal root ganglion neurons. Neuroscience 143,253-263 (2006).
    • (2006) Neuroscience , vol.143 , pp. 253-263
    • Firner, M.1    Greffrath, W.2    Treede, R.D.3
  • 149
    • 0036905264 scopus 로고    scopus 로고
    • Move over protein kinase C, you've got company: Alternative cellular effectors of diacylglycerol and phorbol esters
    • Brose, N. and Rosenmund, C. Move over protein kinase C, you've got company: Alternative cellular effectors of diacylglycerol and phorbol esters. J. Cell Sci. 115, 4399-4411 (2002).
    • (2002) J. Cell Sci , vol.115 , pp. 4399-4411
    • Brose, N.1    Rosenmund, C.2
  • 150
    • 0242321186 scopus 로고    scopus 로고
    • Divergence and complexities in DAG signaling: Looking beyond PKC
    • Yang, C. and Kazanietz, M.G. Divergence and complexities in DAG signaling: Looking beyond PKC. Trends Pharmacol. Sci. 24, 602-608 (2003).
    • (2003) Trends Pharmacol. Sci , vol.24 , pp. 602-608
    • Yang, C.1    Kazanietz, M.G.2
  • 152
    • 0024418739 scopus 로고
    • Second messengers involved in the mechanism of action of bradykinin in sensory neurons in culture
    • Burgess, G.M., Mullaney, I., McNeill, M., Dunn, P.M., and Rang H.P. Second messengers involved in the mechanism of action of bradykinin in sensory neurons in culture. J. Neurosci. 9, 3314-3325 (1989).
    • (1989) J. Neurosci , vol.9 , pp. 3314-3325
    • Burgess, G.M.1    Mullaney, I.2    McNeill, M.3    Dunn, P.M.4    Rang, H.P.5
  • 153
    • 0034700494 scopus 로고    scopus 로고
    • Induction of vanilloid receptor channel activity by protein kinase C
    • Premkumar, L.S. and Ahern, G.P. Induction of vanilloid receptor channel activity by protein kinase C. Nature 408, 985-990 (2000).
    • (2000) Nature , vol.408 , pp. 985-990
    • Premkumar, L.S.1    Ahern, G.P.2
  • 154
    • 0035425705 scopus 로고    scopus 로고
    • Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide
    • Vellani,V., Mapplebeck, S., Moriondo, A., Davis, J.B., and McNaughton, P.A. Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide. J. Physiol. 534, 813-825 (2001).
    • (2001) J. Physiol , vol.534 , pp. 813-825
    • Vellani, V.1    Mapplebeck, S.2    Moriondo, A.3    Davis, J.B.4    McNaughton, P.A.5
  • 155
    • 0029922521 scopus 로고    scopus 로고
    • Activation of protein kinase C augments peptide release from rat sensory neurons
    • Barber, L.A. and Vasko, M.R. Activation of protein kinase C augments peptide release from rat sensory neurons. J. Neurochem. 67, 72-80 (1996).
    • (1996) J. Neurochem , vol.67 , pp. 72-80
    • Barber, L.A.1    Vasko, M.R.2
  • 156
    • 0033166535 scopus 로고    scopus 로고
    • Specific involvement of PKC-epsilon in sensitization of the neuronal response to painful heat
    • Cesare, P., Dekker, L.V., Sardini, A., Parker, P.J., and McNaughton, P.A. Specific involvement of PKC-epsilon in sensitization of the neuronal response to painful heat. Neuron 23, 617-624, (1999).
    • (1999) Neuron , vol.23 , pp. 617-624
    • Cesare, P.1    Dekker, L.V.2    Sardini, A.3    Parker, P.J.4    McNaughton, P.A.5
  • 157
    • 0016767840 scopus 로고
    • Specificity of retrograde transport of nerve growth factor (NGF) in sensory neurons: A biochemical and morphological study
    • Stoeckel, K., Schwab, M., Thoenen, H. Specificity of retrograde transport of nerve growth factor (NGF) in sensory neurons: A biochemical and morphological study. Brain Res. 89, 1-14 (1975).
    • (1975) Brain Res , vol.89 , pp. 1-14
    • Stoeckel, K.1    Schwab, M.2    Thoenen, H.3
  • 158
    • 0037154885 scopus 로고    scopus 로고
    • Retrograde support of neuronal survival without retrograde transport of nerve growth factor
    • MacInnis, B.L., Campenot, R.B. Retrograde support of neuronal survival without retrograde transport of nerve growth factor. Science 295,1536-1539 (2002).
    • (2002) Science , vol.295 , pp. 1536-1539
    • MacInnis, B.L.1    Campenot, R.B.2
  • 159
    • 0034846991 scopus 로고    scopus 로고
    • Nerve growth factor modulates the activation status and fast axonal transport of ERK 1/2 in adult nociceptive neurons
    • Averill, S., Delcroix, J.D., Michael, G.J., Tomlinson, D.R., Fernyhough, P., and Priestley, J.V. Nerve growth factor modulates the activation status and fast axonal transport of ERK 1/2 in adult nociceptive neurons. Mol. Cell. Neurosci. 18, 183-96 (2001).
    • (2001) Mol. Cell. Neurosci , vol.18 , pp. 183-196
    • Averill, S.1    Delcroix, J.D.2    Michael, G.J.3    Tomlinson, D.R.4    Fernyhough, P.5    Priestley, J.V.6
  • 160
    • 21844470486 scopus 로고    scopus 로고
    • Primary afferent nociceptor mechanisms mediating NGF-induced mechanical hyperalgesia
    • Malik-Hall, M., Dina, O.A., and Levine, J.D. Primary afferent nociceptor mechanisms mediating NGF-induced mechanical hyperalgesia. Eur. J. Neurosci. 21, 3387-3394 (2005).
    • (2005) Eur. J. Neurosci , vol.21 , pp. 3387-3394
    • Malik-Hall, M.1    Dina, O.A.2    Levine, J.D.3
  • 161
    • 8544239374 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation
    • Obata, K., Yamanaka, H., Kobayashi, K., Dai, Y., Mizushima, T., Katsura, H., Fukuoka, T., Tokunaga, A., and Noguchi, K. Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation. J. Neurosci. 24,10211-10222 (2004).
    • (2004) J. Neurosci , vol.24 , pp. 10211-10222
    • Obata, K.1    Yamanaka, H.2    Kobayashi, K.3    Dai, Y.4    Mizushima, T.5    Katsura, H.6    Fukuoka, T.7    Tokunaga, A.8    Noguchi, K.9
  • 162
    • 0031045405 scopus 로고    scopus 로고
    • Analysis of cutaneous sensory neurons in transgenic mice lacking the low affinity neurotrophin receptor p75
    • Bergmann. I., Priestley. J.V., McMahon. S.B., Brocker, E.B., Toyka, K.V., and Koltzenburg, M. Analysis of cutaneous sensory neurons in transgenic mice lacking the low affinity neurotrophin receptor p75. Eur. J. Neurosci. 9, 18-28 (1997).
    • (1997) Eur. J. Neurosci , vol.9 , pp. 18-28
    • Bergmann, I.1    Priestley, J.V.2    McMahon, S.B.3    Brocker, E.B.4    Toyka, K.V.5    Koltzenburg, M.6
  • 163
    • 0032475465 scopus 로고    scopus 로고
    • Nerve growth factor evokes hyperalgesia in mice lacking the low-affinity neurotrophin receptor p75
    • Bergmann, I., Reiter, R., Toyka, K.V., and Koltzenburg, M. Nerve growth factor evokes hyperalgesia in mice lacking the low-affinity neurotrophin receptor p75. Neurosci. Lett. 255, 87-90(1998).
    • (1998) Neurosci. Lett , vol.255 , pp. 87-90
    • Bergmann, I.1    Reiter, R.2    Toyka, K.V.3    Koltzenburg, M.4
  • 164
    • 0034803770 scopus 로고    scopus 로고
    • Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system
    • von Schack, D., Casademunt, E., Schweigreiter, R., Meyer, M., Bibel, M., and Dechant, G. Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system. Nat. Neurosci. 4, 977-978 (2001).
    • (2001) Nat. Neurosci , vol.4 , pp. 977-978
    • von Schack, D.1    Casademunt, E.2    Schweigreiter, R.3    Meyer, M.4    Bibel, M.5    Dechant, G.6
  • 165
    • 0023155966 scopus 로고    scopus 로고
    • Kase, H., Iwahashi, K., Nakanishi, S., Matsuda, Y., Yamada, K., Takahashi, M., Murakata, C., Sato, A., and Kaneko, M. K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem. Biophys. Res. Commun. 142, 436-440 (1987).
    • Kase, H., Iwahashi, K., Nakanishi, S., Matsuda, Y., Yamada, K., Takahashi, M., Murakata, C., Sato, A., and Kaneko, M. K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem. Biophys. Res. Commun. 142, 436-440 (1987).
  • 166
    • 0024411048 scopus 로고
    • Selective inhibition of nerve growth factor-stimulated protein kinases by K-252a and 5′-S-methyladenosine in PC12 cells
    • Smith, D.S., King, C.S., Pearson, E., Gittinger, C.K., and Landreth, G.E. Selective inhibition of nerve growth factor-stimulated protein kinases by K-252a and 5′-S-methyladenosine in PC12 cells. J. Neurochem. 53, 800-806 (1989).
    • (1989) J. Neurochem , vol.53 , pp. 800-806
    • Smith, D.S.1    King, C.S.2    Pearson, E.3    Gittinger, C.K.4    Landreth, G.E.5
  • 167
    • 3242757516 scopus 로고    scopus 로고
    • NGF-mediated sensitization of the excitability of rat sensory neurons is prevented by a blocking antibody to the p75 neurotrophin receptor
    • Zhang, Y.-H. and Nicol, G.D. NGF-mediated sensitization of the excitability of rat sensory neurons is prevented by a blocking antibody to the p75 neurotrophin receptor. Neurosci. Lett. 366, 187-192 (2004).
    • (2004) Neurosci. Lett , vol.366 , pp. 187-192
    • Zhang, Y.-H.1    Nicol, G.D.2
  • 169
    • 29244484493 scopus 로고    scopus 로고
    • NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels
    • Zhang, X., Huang, J., and McNaughton, P.A. NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels. EMBO J. 24, 4211-4223 (2005).
    • (2005) EMBO J , vol.24 , pp. 4211-4223
    • Zhang, X.1    Huang, J.2    McNaughton, P.A.3
  • 170
    • 0030960327 scopus 로고    scopus 로고
    • Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione
    • Liu, B. and Hannun, Y.A. Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione. J. Biol. Chem. 272, 16281-16287 (1997).
    • (1997) J. Biol. Chem , vol.272 , pp. 16281-16287
    • Liu, B.1    Hannun, Y.A.2
  • 171
    • 0032079524 scopus 로고    scopus 로고
    • Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death
    • Liu, B., Andrieu-Abadie, N., Levade, T., Zhang, P., Obeid, L.M., and Hannun, Y.A. Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death. J. Biol. Chem. 273, 11313-11320 (1998).
    • (1998) J. Biol. Chem , vol.273 , pp. 11313-11320
    • Liu, B.1    Andrieu-Abadie, N.2    Levade, T.3    Zhang, P.4    Obeid, L.M.5    Hannun, Y.A.6
  • 172
    • 0029090337 scopus 로고
    • Neurotrophins induce sphingomyelin hydrolysis: Modulation by co-expression of p75NTR with Trk receptors
    • Dobrowsky, R.T., Jenkins, G.M., and Hannun, Y.A. Neurotrophins induce sphingomyelin hydrolysis: Modulation by co-expression of p75NTR with Trk receptors. J. Biol. Chem. 270, 22135-22142 (1995).
    • (1995) J. Biol. Chem , vol.270 , pp. 22135-22142
    • Dobrowsky, R.T.1    Jenkins, G.M.2    Hannun, Y.A.3
  • 173
    • 0030752208 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor binding to the p75 neurotrophin receptor reduces TrkA signaling while increasing serine phosphorylation in the TrkA intracellular domain
    • MacPhee, I.J. and Barker, P.A. Brain-derived neurotrophic factor binding to the p75 neurotrophin receptor reduces TrkA signaling while increasing serine phosphorylation in the TrkA intracellular domain. J. Biol. Chem. 272, 23547-23551 (1997).
    • (1997) J. Biol. Chem , vol.272 , pp. 23547-23551
    • MacPhee, I.J.1    Barker, P.A.2
  • 174
    • 27444433045 scopus 로고    scopus 로고
    • The p62 scaffold regulates nerve growth factor-induced NF-kappaB activation by influencing TRAF6 polyubiquitination
    • Wooten, M.W., Geetha, T., Seibenhener, M.L., Babu, J.R., Diaz-Meco, M.T., and Moscat, J. The p62 scaffold regulates nerve growth factor-induced NF-kappaB activation by influencing TRAF6 polyubiquitination. J. Biol. Chem. 280, 35625-35629 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 35625-35629
    • Wooten, M.W.1    Geetha, T.2    Seibenhener, M.L.3    Babu, J.R.4    Diaz-Meco, M.T.5    Moscat, J.6
  • 175
    • 0042164216 scopus 로고    scopus 로고
    • Individual and combined effects of TrkA and p75NTR nerve growth factor receptors. A role for the high-affinity receptor site
    • Lad, S.P., Peterson, D.A., Bradshaw, R.A., and Neet, K.E. Individual and combined effects of TrkA and p75NTR nerve growth factor receptors. A role for the high-affinity receptor site. J. Biol. Chem. 278, 24808-24817 (2003).
    • (2003) J. Biol. Chem , vol.278 , pp. 24808-24817
    • Lad, S.P.1    Peterson, D.A.2    Bradshaw, R.A.3    Neet, K.E.4
  • 176
    • 0025197271 scopus 로고
    • 2+-current by a serum factor in cultured dorsal root ganglia neurons of the adult guinea pig
    • 2+-current by a serum factor in cultured dorsal root ganglia neurons of the adult guinea pig. Brain Res. 529, 286-293 (1990).
    • (1990) Brain Res , vol.529 , pp. 286-293
    • Yamaguchi, K.1


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