Effects of low-dose intramuscular ketorolac on experimental pain in the masseter muscle of healthy women

Journal of Oral and Facial Pain and Headache

Volumn 24, Issue 4, 2010, Pages 398-407

  Bendixen, Karina H ^a   Baad Hansen, Lene ^a   Cairns, Brian E ^b   Svensson, Peter ^a,c  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Experimental muscle pain; Ketorolac; Local anesthetics; NSAIDs; Trigeminal nociception

Indexed keywords

KETOROLAC; LIDOCAINE; LOCAL ANESTHETIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; SODIUM CHLORIDE;

ADULT; ANALYSIS OF VARIANCE; AREA UNDER THE CURVE; ARTICLE; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FACE PAIN; FEMALE; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; JOINT CHARACTERISTICS AND FUNCTIONS; MASSETER MUSCLE; NONPARAMETRIC TEST; PAIN ASSESSMENT; PAIN THRESHOLD; RANDOMIZED CONTROLLED TRIAL;

ADULT; ANALYSIS OF VARIANCE; ANESTHETICS, LOCAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FACIAL PAIN; FEMALE; HUMANS; INJECTIONS, INTRAMUSCULAR; KETOROLAC; LIDOCAINE; MASSETER MUSCLE; PAIN MEASUREMENT; PAIN THRESHOLD; RANGE OF MOTION, ARTICULAR; SALINE SOLUTION, HYPERTONIC; STATISTICS, NONPARAMETRIC; YOUNG ADULT;

EID: 79952263361     PISSN: 23330384     EISSN: 23330376     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. LeResche L. Epidemiology of temporomandibular disorders: Implications for the investigation of etiologic factors. Crit Rev Oral Biol Med 1997;8:291-305
2. Fillingim RB, Maixner W. Sex-related factors in temporomandibular disorders. In: Fillingim RB (ed). Sex, Gender and Pain. Seattle: IASP, 2000:309-325
3. Carlsson GE, LeResche L. Epidemiology of temporomandibular disorders. In: Sessle B, Bryant P, Dionne R (eds). Temporomandibular Disorders and Related Pain Conditions. Seattle: IASP, 1995:497-506
4. Drangsholt M, LeResche L. Temporomandibular disorder pain. In: Crombie IK (ed). Epidemiology of Pain. Seattle: IASP, 1999:497-506
5. Dao TT, LeResche L. Gender differences in pain. J Orofac Pain 2000;14:169-184
6. Curatolo M, Bogduk N. Pharmacologic pain treatment of musculoskeletal disorders: Current perspectives and future prospects. Clin J Pain 2001;17:25-32
7. Stohler CS. Clinical perspectives on masticatory and related muscle disorders. In: Sessle BJ, Bryant PS, Dionne RA (eds). Temporomandibular Disorders and Related Pain Conditions. Seattle: IASP, 1995:3-29
8. Singer E, Dionne R. Controlled evaluation of ibuprofen and diazepam for chronic orofacial muscle pain. J Orofac Pain 1997;11:139-146
9. Dionne RA. Pharmacologic treatments for temporomandibular disorders. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997;83:134-142
10. Svensson P. Orofacial musculoskeletal pain. In: Giamberardino MA (ed). Pain 2002, An Updated Review: Refresher Course Syllabus. Seattle: IASP, 2002:447-458
11. Gotzsche PC. Non-steroidal anti-inflammatory drugs. BMJ 2000;320:1058-1061
12. Cashman JN. The mechanisms of action of NSAIDs in analgesia. Drugs 1996;52:13-23
13. Walker JS. NSAIDs: An update on their analgesic effects. Clin Exp Pharmacol Physiol 1995;22:855-860
14. Gordon SM, Brahim JS, Rowan J, Kent A, Dionne RA. Peripheral prostanoid levels and nonsteroidal anti-inflammatory drug analgesia: Replicate clinical trials in a tissue injury model. Clin Pharmacol Ther 2002;72:175-183
15. Cairns BE, Mann MK, Mok E, Dong XD, Svensson P. Diclofenac exerts local anesthetic-like actions on rat masseter muscle afferent fibers. Brain Res 2008;1194:56-64
16. Dong XD, Svensson P, Cairns BE. The analgesic action of topical diclofenac may be mediated through peripheral NMDA receptor antagonism. Pain 2009;147:36-45
17. Moore RA, Tramer MR, Carroll D, Wiffen PJ, McQuay HJ. Quantitative systematic review of topically applied non-steroidal anti-inflammatory drugs. BMJ 1998;316:333-338
18. Galer BS, Rowbotham M, Perander J, Devers A, Friedman E. Topical diclofenac patch relieves minor sports injury pain: Results of a multicenter controlled clinical trial. J Pain Symp Manag 2000;19:287-294
19. Di Rienzo Businco L, Di Rienzo Businco A, D'Emilia M, Lauriello M, Coen Tirelli G. Topical versus systemic diclofenac in the treatment of temporomandibular joint dysfunction symptoms. Acta Otorhinolaryngol Ital 2004;24:279-285
20. Kuo CC, Huang RC, Lou BS. Inhibition of Na(+) current by diphenhydramine and other diphenyl compounds: Molecular determinants of selective binding to the inactivated channels. Mol Pharmacol 2000;57:135-143
21. Kellgren JH. Observations on referred pain arising from muscle. Clin Sci 1938;3:175-190
22. Svensson P, Graven-Nielsen T. Craniofacial muscle pain: Review of mechanisms and clinical manifestations. J Orofac Pain 2001;15:117-145
23. Dworkin SF, LeResche L. Research diagnostic criteria for temporomandibular disorders: Review, criteria, examinations and specifications, critique. J Craniomandib Disord 1992;6:301-355
24. Svensson P, Arendt-Nielsen L, Nielsen H, Larsen JK. Effect of chronic and experimental jaw muscle pain on pain-pressure thresholds and stimulus-response curves. J Orofac Pain 1995;9:347-356
25. Svensson P, Graven-Nielsen T, Arendt-Nielsen L. Mechanical hyperesthesia of human facial skin induced by tonic painful stimulation of jaw muscles. Pain 1998;74:93-100
26. Svensson P. Effects of human jaw-muscle pain on somato sensory and motor function: Experimental studies and clinical implications [thesis]. Aarhus: Aarhus Universitet, 2000
27. Graven-Nielsen T, Arendt-Nielsen L, Svensson P, Jensen TS. Experimental muscle pain: A quantitative study of local and referred pain in humans following injection of hypertonic saline. J Musculoskel Pain 1997;5:49-69
28. Graven-Nielsen T, Babenko V, Svensson P, Arendt-Nielsen L. Experimentally induced muscle pain induces hypoalgesia in heterotopic deep tissues, but not in homotopic deep tissues. Brain Res 1998;787:203-210
29. Graven-Nielsen T, Mense S. The peripheral apparatus of muscle pain: Evidence from animal and human studies. Clin J Pain 2001;17:2-10
30. Cairns BE, Svensson P, Wang K, et al. Ketamine attenuates glutamate-induced mechanical sensitization of the masseter muscle in human males. Exp Brain Res 2006;169:467-472
31. Melzack R. The McGill pain questionnaire: Major properties and scoring methods. Pain 1975;1:277-299
32. Drewes AM, Helweg-Larsen S, Petersen P, et al. McGill pain questionnaire translated into Danish: Experimental and clinical findings. Clin J Pain 1993;9:80-87
33. Sherman JJ, LeResche L. Does experimental pain response vary across the menstrual cycle? A methodological review. Am J Physiol Regul Integr Comp Physiol 2006;291:245-256
34. Isselee H, De Laat A, De Mot B, Lysens R. Pressure-pain threshold variation in temporomandibular disorder myalgia over the course of the menstrual cycle. J Orofac Pain 2002;16:105-117
35. Drobek W, Schoenaers J, De Laat A. Hormone-dependent fluctuations of pressure pain threshold and tactile threshold of the temporalis and masseter muscle. J Oral Rehabil 2002;29:1042-1051
36. Sherman JJ, LeResche L, Mancl LA, Huggins K, Sage JC, Dworkin SF. Cyclic effects on experimental pain response in women with temporomandibular disorders. J Orofac Pain 2005;19:133-143
37. Svensson P. What can human experimental pain models teach us about clinical TMD? Arch Oral Biol 2007;52:391-394
38. Wang K, Svensson P, Arendt-Nielsen L. Modulation of exteroceptive suppression periods in human jaw-closing muscles by local and remote experimental muscle pain. Pain 1999;82:253-262
39. Svensson P, Cairns BE, Wang K, et al. Glutamate-evoked pain and mechanical allodynia in the human masseter muscle. Pain 2003;101:221-227
40. Sotgiu ML, Biella G, Formaglio F, Marchettini P. Central effect of ketorolac involving NMDA receptors activity. Brain Res 1998;813:223-226
41. Juhl GI, Svensson P, Norholt SE, Jensen TS. Long-lasting mechanical sensitization following third molar surgery. J Orofac Pain 2006;20:59-73
42. Terkelsen AJ, Bach FW, Jensen TS. Experimental forearm immobilization in humans induces cold and mechanical hyperalgesia. Anesthesiology 2008;109:297-307
43. Baad-Hansen L, Cairns BE, Ernberg Malin, Svensson P. Effect of systemic monosodium glutamate (MSG) on headache and pericranial muscle sensitivity. Cephalalgia 2010;30:68-76
44. Cairns BE, Gambarota G, Dunning PS, Mulkern RV, Berde CB. Activation of peripheral excitatory amino acid receptors decreases the duration of local anesthesia. Anesthesiology 2003;98:521-529