Imipramine decreases oesophageal pain perception in human male volunteers

Gut

Volumn 42, Issue 6, 1998, Pages 807-813

  Peghini, P L ^a   Katz, P O ^a   Castell, D O ^a  

^a ALLEGHENY UNIVERSITY HOSPITALS   (United States)

Author keywords

Antidepressants; Distension; Functional bowel syndromes; Imipramine; Oesophageal balloon; Visceral hyperalgesia

Indexed keywords

IMIPRAMINE;

ADULT; ANALGESIA; ANTINOCICEPTION; ARTICLE; DRUG EFFECT; ESOPHAGUS PRESSURE; HUMAN; HUMAN EXPERIMENT; MALE; NOCICEPTION; NORMAL HUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; VISCERAL PAIN;

EID: 0031862833     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.42.6.807     Document Type: Article

References (47)

1. Mayer HA, Gebhart GF. Basic and clinical aspects of visceral hyperalgesia. Gastroenterology 1994;107:271-93.
2. Barish CF, Castell DO, Richter JE. Graded oesophageal balloon distention: a new provocative lest for noncardiac chest pain. Dig Dis Sci 1986;31:1292-8.
3. Richter JE, Barish CF, Castell DO. Abnormal sensory perception in patients with oesophageal chest pain. Gastroenterology 1986;91:845-52.
4. Lémann M, Dederding JP, Flourié B, et al. Abnormal perception of visceral pain in response to gastric distension in chronic idiopathic dyspepsia - the irritable stomach syndrome. Dig Dis Sci 1991;36:1249-54.
5. Ritchie J. Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome. Gut 1973;14: 125-32.
6. Costantini M, Sturniolo GC, Zaninotto G, et al. Altered oesophageal pain threshold in irritable bowel syndrome. Dig Dis Sci 1993;38:206-12.
7. Trimble KC, Farouk R, Pryde A, et al. Heightened visceral sensation in functional gastrointestinal disease is not site specific: evidence for a generalized disorder of gut sensitivity. Dig Dis Sci 1995;40:1607-13.
8. De Caestecker JS, Pryde A, Heading RC. Site and mechanism of pain perception with oesophageal balloon distention and intravenous edrophonium in patients with oesophageal chest pain. Gut 1992;33:580-6.
9. Mayer EA, Raybould HE. Role of visceral afferent mechanisms in functional bowel disorders. Gastroenterology 1990;99:1688-704.
10. Cook IJ, van Eeden A, Collins SM. Patients with irritable bowel syndrome have a greater pain tolerance than normal subjects. Gastroenterology 1987;93:727-33.
11. Whitehead WE, Holtkotter B, Enck P, et al. Tolerance for rectosigmoid distention in irritable bowel syndrome. Gastroenterology 1990;98:1187-92.
12. Egbunike IG, Chaffee BJ. Antidepressants in the management of chronic pain syndromes. Pharmacotherapy 1990; 10:262-70.
13. Max MB, Lynch SA, Muir J, et al. Effects of desipramine, amitriptyline and fluoxetine on pain in diabetic neuropathy. N Engl J Med 1992;326:1250-6.
14. Kvinesdal B, Molin J, Froland A, et al. Imipramine treatment of painful diabetic neuropathy. JAMA 1984;251: 1727-30.
15. Sindrup SH, Brosen K, Gram LF. Antidepressants in pain treatment: antidepressant or analgesic effect? Clin Neuropharm 1992;15:636A-637A.
16. Feinman C. Pain relief by antidepressants: possible modes of action. Pain 1985;23:1-8.
17. France RD, Houpt JL, Ellinwood EH. Therapeutic effects of antidepressants in chronic pain. Gen Hosp Psychiatry 1984;6:55-63.
18. Magni G. The use of antidepressants in the treatment of chronic pain. Drugs 1991;42:730-48.
19. Cannon RO, Quyyumi AA, Mincemoyer R, et al. Imipramine in patients with chest pain despite normal coronary angiograms. N Engl J Med 1994;330:1411-17.
20. Clouse RE, Lustman PJ, Geisman RA, et al. Antidepressant therapy in 138 patients with irritable bowel syndrome: a five-year clinical experience. Aliment Pharmacol Ther 1994; 8:409-16.
21. Sindrup SH, Brosen K, Gram LF. The mechanism of action of antidepressants in pain treatment: controlled cross-over studies in diabetic neuropathy. Clin Neuropharmacol 1992;15:380A-1A.
22. Clouse RE, Lustman PJ, Eckert TC, et al. Low-dose trazodone for symptomatic patients with oesophageal contraction abnormalities. Gastroenterology 1987;92:1027-36.
23. Greenbaum DS, Mayle JE, Vanegeren LE, et al. Effects of desipramine on irritable bowel syndrome compared with atropine and placebo. Dig Dis Sci 1987;32:257-66.
24. Mertz HR, Fass R, Hirsh T, et al. Amitriptyline for functional dyspepsia: effect on symptoms, gastric sensitivity and sleep [abstract]. Gastroenterology 1995;108:A649.
25. Bromm B, Meier W, Scharein E. Imipramine reduces experimental pain. Pain 1986;25:245-57.
26. Lasch H, DeVault KR, Castell DO. Intraesophageal balloon distention in the evaluation of sensory thresholds: studies on reproducibility and comparison of balloon composition. Am J Gastroenterol 1994;89:1185-90.
27. DeVault KR, Castell DO. Esophageal balloon distention and cerebral evoked potential recording in the evaluation of unexplained chest pain. Am J Med 1992;92(suppl 5A): 20S-26S.
28. Barlow JD, Thompson DG. Reproducibility of perception to ooesophageal distension. Gut 1994;35(suppl 2):S8.
29. Hazan S, Steinberg A, Morris N, et al. Long-term reproducibility of intraoesophageal balloon distention [abstract]. Gastroenterology 1997;112:A145.
30. Sato TL, Madakasira S. Monitoring tricyclic antidepressant plasma levels. Am Fam Physician 1984;29:199-202.
31. Montastruc JL, Tran MA, Blanc M, et al. Measurement of plasma levels of clomiparmine in the treatment of chronic pain. Clin Neuropharmacol 1985;8:78-82.
32. Baldessarini RJ. Drugs and the treatment of psychiatric disorders. In: Goodman and Gilman, eds. The pharmacological basis of therapeutics. 8th edn. New York: Pergamon Press, 1990:405-23.
33. Botney M, Fields H. Amitriptyline potentiates morphine analgesia by a direct action on the CNS. Ann Neurol 1983; 13:160-4.
34. Isenberg KE, Cicero TJ. Possible involvement of opiate receptors in the pharmacological profiles of antidepressant compounds. Eur J Pharmacol 1984;103:57-63.
35. Paterson WG, Selucky M, Hynna-Liepert TT. Effect of intraesophageal location and muscarinic blockade on balloon distension-induced chest pain. Dig Dis Sci 1991;36: 282-8.
36. Drachman DB. Myasthenia gravis. In: Isselbacher KJ, et al, eds. Harrison's principles of internal medicine. 13th edn. New York: McGraw-Hill, 1995:2393-6.
37. Lynn RB. Mechanisms of oesophageal pain. Am J Med 1992;92(suppl 5A):11S-19S.
38. Bueno L, Fioramonti J, Delvaux M, et al. Mediators and pharmacology of visceral sensitivity: from basic to clinical investigations. Gastroenterology 1997;112:1714-13.
39. Rao SSC, Hayek B, Summers RW. Unexplained chest pain: oesophageal hypersensitivity or motor dysfunction? [abstract]. Gastroenterology 1997;112:A810.
40. Wang JK. Antinociceptive effect of intrathecally administered serotonin. Anesthesiology 1977;47:269-71.
41. Rao SSC, Gregersen H, Hayek B, et al. Unexplained chest pain: the hypersensitive, hyperreactive, and poorly compli ant esophagus. Ann Intern Med 1996;124:950-8.
42. Fass R. Unexplained noncardiac chest pain [letter]. Ann Intern Med 1997;126:662.
43. Peghini PL, Castell DO. Does sensitization of esophageal mucosal receptors occur during provocative testing? Am J Gastroenterol 1997;92:919-20.
44. Kahrilas PJ. Functional anatomy and physiology of the esophagus. In: Castell DO, ed. The esophagus 2nd edn. Boston: Little, Brown, 1995:1-28.
45. Naliboff B, Mayer EA. Sensational developments in the irritable bowel. Gut 1996;39:770-1.
46. Silverman DHS, Munakata JA, Ennes H, et al. Regional cerebral activity in normal and pathological perception of visceral pain. Gastroenterology 1997;112:64-72.
47. Becker K, Kuhlbusch R, Enck P, et al. Effect of topical anaesthesia on oesophageal sensory and motor function in healthy subjects. Neurogastroenterol Motil 1994;6:255-61.