Affinity, potency and efficacy of tramadol and its metabolites at the cloned human μ-opioid receptor

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 362, Issue 2, 2000, Pages 116-121

  Gillen, C ^a   Haurand, M ^a   Kobelt, D J ^a   Wnendt, S ^a  

^a GRÜNENTHAL GMBH   (Germany)

Author keywords

Affinity; Analgesics; Efficacy; GTP S; Human opioid receptor; Tramadol

Indexed keywords

DRUG METABOLITE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; FENTANYL; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); LEVOMETHADONE; MORPHINE; MU OPIATE RECEPTOR; NALOXONE; OPIATE AGONIST; SULFUR 35; TRAMADOL; TRITIUM;

ANALGESIA; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHO CELL; COMPETITIVE INHIBITION; DRUG EFFICACY; DRUG METABOLISM; DRUG POTENCY; DRUG RECEPTOR BINDING; NONHUMAN; PAIN;

ANALGESICS, OPIOID; ANIMALS; BINDING, COMPETITIVE; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; NALOXONE; NARCOTIC ANTAGONISTS; RECEPTORS, OPIOID, MU; TRAMADOL;

EID: 0033901486     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002100000266     Document Type: Article

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