메뉴 건너뛰기




Volumn 60, Issue 6, 1996, Pages 636-644

The hypoalgesic effect of tramadol in relation to CYP2D6

Author keywords

[No Author keywords available]

Indexed keywords

OPIATE RECEPTOR; PLACEBO; TRAMADOL;

EID: 0030471120     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9236(96)90211-8     Document Type: Article
Times cited : (376)

References (36)
  • 1
    • 0027194499 scopus 로고
    • Tramadol: A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutical potential in acute and chronic pain
    • Lee CR, McTavish D, Sorkin EM. Tramadol: a preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutical potential in acute and chronic pain. Drugs 1993;46:313-40.
    • (1993) Drugs , vol.46 , pp. 313-340
    • Lee, C.R.1    McTavish, D.2    Sorkin, E.M.3
  • 2
    • 0017876343 scopus 로고
    • Pharmakologische Untersuchungen zur Analgesie, Abhängigkeits- und Toleranzentwicklung von Tramadol, einem stark wirkenden Analgetikum
    • Friderichs E, Felgenhauer F, Jongschaap P, Osterloh G. Pharmakologische Untersuchungen zur Analgesie, Abhängigkeits- und Toleranzentwicklung von Tramadol, einem stark wirkenden Analgetikum. Arzneimittelforschung 1978;28:122-34.
    • (1978) Arzneimittelforschung , vol.28 , pp. 122-134
    • Friderichs, E.1    Felgenhauer, F.2    Jongschaap, P.3    Osterloh, G.4
  • 3
    • 0017863203 scopus 로고
    • Über die Isomerentrennung, Strukturaufklärung und pharmakologische Charakterisierung von 1-(m-Methoxyphenyl)-2-(dimethylaminomethyl)-cyclohexan-1-ol
    • Frankus E, Friderichs E, Kim SM, Osterloh G. Über die Isomerentrennung, Strukturaufklärung und pharmakologische Charakterisierung von 1-(m-Methoxyphenyl)-2-(dimethylaminomethyl)-cyclohexan-1-ol. Arzneimittelforschung 1978;28:114-21.
    • (1978) Arzneimittelforschung , vol.28 , pp. 114-121
    • Frankus, E.1    Friderichs, E.2    Kim, S.M.3    Osterloh, G.4
  • 6
    • 0017879150 scopus 로고
    • Klinische Prüfung der Abhängigkeitsentwicklung nach Langzeitapplikation von Tramadol
    • Flohé L, Arend I, Cogal A, Richter W, Simon W. Klinische Prüfung der Abhängigkeitsentwicklung nach Langzeitapplikation von Tramadol. Arzneimittelforschung 1978;28:213-7.
    • (1978) Arzneimittelforschung , vol.28 , pp. 213-217
    • Flohé, L.1    Arend, I.2    Cogal, A.3    Richter, W.4    Simon, W.5
  • 7
    • 0026011542 scopus 로고
    • Abuse potential and pharmacological comparison of tramadol and morphine
    • Preston KL, Jasinski DR, Testa M. Abuse potential and pharmacological comparison of tramadol and morphine. Drug Alcohol Depend 1991;27:7-17.
    • (1991) Drug Alcohol Depend , vol.27 , pp. 7-17
    • Preston, K.L.1    Jasinski, D.R.2    Testa, M.3
  • 8
    • 0026512239 scopus 로고
    • Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic
    • Raffa RB, Friderichs E, Reimann W, Shank RP, Codd EE, Vaught JL. Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic. J Pharmacol Exp Ther 1992;260:275-85.
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 275-285
    • Raffa, R.B.1    Friderichs, E.2    Reimann, W.3    Shank, R.P.4    Codd, E.E.5    Vaught, J.L.6
  • 9
    • 0026564002 scopus 로고
    • Evidence for noradrenergic component in the antinociceptive effect of the analgesic agent tramadol in an animal model of clinical pain, the arthritic rat
    • Kayser V, Besson JM, Guilbaud G. Evidence for noradrenergic component in the antinociceptive effect of the analgesic agent tramadol in an animal model of clinical pain, the arthritic rat. Eur J Pharmacol 1992; 224:83-8.
    • (1992) Eur J Pharmacol , vol.224 , pp. 83-88
    • Kayser, V.1    Besson, J.M.2    Guilbaud, G.3
  • 10
    • 0026585612 scopus 로고
    • Interaction of the central analgesic, tramadol, with the uptake and release of 5-hydroxytryptamine in the rat brain in vitro
    • Driessen B, Reimann W. Interaction of the central analgesic, tramadol, with the uptake and release of 5-hydroxytryptamine in the rat brain in vitro. Br J Pharmacol 1992;105:147-51.
    • (1992) Br J Pharmacol , vol.105 , pp. 147-151
    • Driessen, B.1    Reimann, W.2
  • 11
    • 0022886435 scopus 로고
    • Multiple opioid systems and pain
    • Millan MJ. Multiple opioid systems and pain. Pain 1986;27:303-47.
    • (1986) Pain , vol.27 , pp. 303-347
    • Millan, M.J.1
  • 14
    • 0026649268 scopus 로고
    • The metabolism of tramadol by human liver microsomes
    • Paar WD, Frankus P, Dengler HJ. The metabolism of tramadol by human liver microsomes. Clin Invest 1992;70:708-10.
    • (1992) Clin Invest , vol.70 , pp. 708-710
    • Paar, W.D.1    Frankus, P.2    Dengler, H.J.3
  • 15
    • 0025572192 scopus 로고
    • Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations
    • Alván G, Bechtel P, Iselius L, Gundert-Remy U. Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations. Eur J Clin Pharmacol 1990;39:533-7.
    • (1990) Eur J Clin Pharmacol , vol.39 , pp. 533-537
    • Alván, G.1    Bechtel, P.2    Iselius, L.3    Gundert-Remy, U.4
  • 16
    • 0023795013 scopus 로고
    • Polymorphic O-demethylation of codeine
    • Chen ZR, Somogyi AA, Bochner F. Polymorphic O-demethylation of codeine. Lancet 1988;2:914-5.
    • (1988) Lancet , vol.2 , pp. 914-915
    • Chen, Z.R.1    Somogyi, A.A.2    Bochner, F.3
  • 17
    • 0023884310 scopus 로고
    • Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufl)
    • Dayer P, Desmeules J, Leemann T, Striberni R. Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufl). Biochem Biophys Res Commun 1988;152:411-6.
    • (1988) Biochem Biophys Res Commun , vol.152 , pp. 411-416
    • Dayer, P.1    Desmeules, J.2    Leemann, T.3    Striberni, R.4
  • 18
    • 0024306112 scopus 로고
    • Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation
    • Yue QY, Svensson JO, Aim C, Sjöqvist F, Säwe J. Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation. Br J Clin Pharmacol 1989;28:639-45.
    • (1989) Br J Clin Pharmacol , vol.28 , pp. 639-645
    • Yue, Q.Y.1    Svensson, J.O.2    Aim, C.3    Sjöqvist, F.4    Säwe, J.5
  • 19
    • 0025649038 scopus 로고
    • Codeine increases pain thresholds to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine
    • Sindrup SH, Brøsen K, Bjerring P, Arendt-Nielsen L, Larson U, Angelo HR, et al. Codeine increases pain thresholds to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine. Clin Pharmacol Ther 1990;48:686-93.
    • (1990) Clin Pharmacol Ther , vol.48 , pp. 686-693
    • Sindrup, S.H.1    Brøsen, K.2    Bjerring, P.3    Arendt-Nielsen, L.4    Larson, U.5    Angelo, H.R.6
  • 22
    • 0030472254 scopus 로고    scopus 로고
    • Codeine and morphine in extensive and poor metabolizers of sparteine: Pharmacokinetics, analgesic effect and side effects
    • in press
    • Poulsen L, Brøsen K, Arendt-Nielsen L, Gram LF, Elbaek K, Sindrup SH. Codeine and morphine in extensive and poor metabolizers of sparteine: pharmacokinetics, analgesic effect and side effects. Eur J Clin Pharmacol [in press].
    • Eur J Clin Pharmacol
    • Poulsen, L.1    Brøsen, K.2    Arendt-Nielsen, L.3    Gram, L.F.4    Elbaek, K.5    Sindrup, S.H.6
  • 24
    • 0024396184 scopus 로고
    • Measurements of human pressure-pain thresholds on fingers and toes
    • Brennum J, Kjeldsen M, Jensen K, Jensen TS. Measurements of human pressure-pain thresholds on fingers and toes. Pain 1989;38:211-7.
    • (1989) Pain , vol.38 , pp. 211-217
    • Brennum, J.1    Kjeldsen, M.2    Jensen, K.3    Jensen, T.S.4
  • 25
    • 0023790033 scopus 로고
    • Morphine and ibuprofen compared using the cold pressor test
    • Jones SF, McQuay HJ, Moore RA, Hand CW. Morphine and ibuprofen compared using the cold pressor test. Pain 1988;34:117-22.
    • (1988) Pain , vol.34 , pp. 117-122
    • Jones, S.F.1    McQuay, H.J.2    Moore, R.A.3    Hand, C.W.4
  • 26
    • 0023056654 scopus 로고
    • Determination of tramadol in human serum by capillary gas chromatography with nitrogen-selective detection
    • Becker R, Lintz W. Determination of tramadol in human serum by capillary gas chromatography with nitrogen-selective detection. J Chromatogr 1986;377: 213-20.
    • (1986) J Chromatogr , vol.377 , pp. 213-220
    • Becker, R.1    Lintz, W.2
  • 28
    • 0023947896 scopus 로고
    • Calculating confidence intervals for some non-parametric analyses
    • Campbell MJ, Gardner MJ. Calculating confidence intervals for some non-parametric analyses. Br Med J 1988;296:1454-6.
    • (1988) Br Med J , vol.296 , pp. 1454-1456
    • Campbell, M.J.1    Gardner, M.J.2
  • 29
    • 0021345446 scopus 로고
    • Competitive inhibition of sparteine oxidation in human liver by beta-adrenoreceptor antagonists and other cardiovascular drugs
    • Otton SV, Inaba T, Kalow W. Competitive inhibition of sparteine oxidation in human liver by beta-adrenoreceptor antagonists and other cardiovascular drugs. Life Sci 1984;34:73-80.
    • (1984) Life Sci , vol.34 , pp. 73-80
    • Otton, S.V.1    Inaba, T.2    Kalow, W.3
  • 31
    • 0030033533 scopus 로고    scopus 로고
    • Contribution of monoaminergic modulation to the analgesic effect of tramadol
    • Desmeules JA, Piquet V, Collart L, Dayer P. Contribution of monoaminergic modulation to the analgesic effect of tramadol. Br J Clin Pharmacol 1996;41:7-12.
    • (1996) Br J Clin Pharmacol , vol.41 , pp. 7-12
    • Desmeules, J.A.1    Piquet, V.2    Collart, L.3    Dayer, P.4
  • 33
    • 0028206513 scopus 로고
    • Antidepressants in the treatment of diabetic neuropathy symptoms. Pharmacodynamic, -kinetic and -genetic aspects
    • Sindrup SH. Antidepressants in the treatment of diabetic neuropathy symptoms. Pharmacodynamic, -kinetic and -genetic aspects. Dan Med Bull 1994;41:66-78.
    • (1994) Dan Med Bull , vol.41 , pp. 66-78
    • Sindrup, S.H.1
  • 34
    • 0000866460 scopus 로고    scopus 로고
    • Antidepressants as analgesics
    • Biebuyck JF, Lynch C, Maze M, et al, editors. New York: Raven Press [in press]
    • Sindrup SH. Antidepressants as analgesics. In: Biebuyck JF, Lynch C, Maze M, et al, editors. Anesthesia: biological foundations. New York: Raven Press [in press].
    • Anesthesia: Biological Foundations
    • Sindrup, S.H.1
  • 35
    • 0026033790 scopus 로고
    • Pain and hyperalgesia following tissue injury: New mechanisms and new treatments
    • Dubner R. Pain and hyperalgesia following tissue injury: new mechanisms and new treatments. Pain 1991; 44:213-4.
    • (1991) Pain , vol.44 , pp. 213-214
    • Dubner, R.1
  • 36
    • 1942462395 scopus 로고
    • Pain models in healthy volunteers
    • Nimmo WS, Tucker G, editors. London: Wolfe
    • Posner J. Pain models in healthy volunteers. In: Nimmo WS, Tucker G, editors. Clinical measurements in drug evaluation. London: Wolfe 1991:73-90.
    • (1991) Clinical Measurements in Drug Evaluation , pp. 73-90
    • Posner, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.