메뉴 건너뛰기




Volumn 151, Issue , 2015, Pages 141-151

Targeting Cdc20 as a novel cancer therapeutic strategy

Author keywords

Cancer; Cdc20; Drug; E3 ligase; SCF; Target

Indexed keywords

6 BROMINATED COUMARIN HYDRAZIDE HYDRAZONE DERIVATIVE; ANAPHASE PROMOTING COMPLEX; ANTINEOPLASTIC AGENT; APCIN; AURORA A KINASE; AURORA B KINASE; BORTEZOMIB; CARFILZOMIB; CARP 1 FUNCTIONAL MIMETIC 4; CELL CYCLE PROTEIN 20; CELL CYCLE PROTEIN 20 INHIBITOR; CELL CYCLE PROTEIN 6; CYCLIN A2; DELANZOMIB; GANODERMANONTRIOL; GEMININ; GENISTEIN; OPROZOMIB; POLO LIKE KINASE 1; PRO TOSYLARGININE METHYL ESTER; PROTEIN; PROTEIN INHIBITOR; S PHASE KINASE ASSOCIATED PROTEIN 2; SALINOSPORAMIDE A; SULFONAMIDE; TOSYLARGININE METHYL ESTER; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; UNINDEXED DRUG; UVOMORULIN; WITHAFERIN A; CDC20 PROTEIN, HUMAN;

EID: 84930088030     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2015.04.002     Document Type: Review
Times cited : (200)

References (155)
  • 1
    • 2342613652 scopus 로고    scopus 로고
    • The proteasome: A suitable antineoplastic target
    • J. Adams The proteasome: a suitable antineoplastic target Nat Rev Cancer 4 2004 349 360
    • (2004) Nat Rev Cancer , vol.4 , pp. 349-360
    • Adams, J.1
  • 2
    • 10744232926 scopus 로고    scopus 로고
    • Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim
    • T. Akiyama, P. Bouillet, T. Miyazaki, Y. Kadono, H. Chikuda, and U.I. Chung Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim EMBO J 22 2003 6653 6664
    • (2003) EMBO J , vol.22 , pp. 6653-6664
    • Akiyama, T.1    Bouillet, P.2    Miyazaki, T.3    Kadono, Y.4    Chikuda, H.5    Chung, U.I.6
  • 3
    • 73149112184 scopus 로고    scopus 로고
    • Bim-targeted cancer therapy: A link between drug action and underlying molecular changes
    • T. Akiyama, C.R. Dass, and P.F. Choong Bim-targeted cancer therapy: a link between drug action and underlying molecular changes Mol Cancer Ther 8 2009 3173 3180
    • (2009) Mol Cancer Ther , vol.8 , pp. 3173-3180
    • Akiyama, T.1    Dass, C.R.2    Choong, P.F.3
  • 4
    • 79959617179 scopus 로고    scopus 로고
    • Bim: Guardian of tissue homeostasis and critical regulator of the immune system, tumorigenesis and bone biology
    • T. Akiyama, and S. Tanaka Bim: guardian of tissue homeostasis and critical regulator of the immune system, tumorigenesis and bone biology Arch Immunol Ther Exp (Warsz) 59 2011 277 287
    • (2011) Arch Immunol Ther Exp (Warsz) , vol.59 , pp. 277-287
    • Akiyama, T.1    Tanaka, S.2
  • 6
    • 34547174700 scopus 로고    scopus 로고
    • APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase
    • V. Amador, S. Ge, P.G. Santamaria, D. Guardavaccaro, and M. Pagano APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase Mol Cell 27 2007 462 473
    • (2007) Mol Cell , vol.27 , pp. 462-473
    • Amador, V.1    Ge, S.2    Santamaria, P.G.3    Guardavaccaro, D.4    Pagano, M.5
  • 8
    • 0344442825 scopus 로고    scopus 로고
    • Degradation of origin recognition complex large subunit by the anaphase-promoting complex in Drosophila
    • M. Araki, R.P. Wharton, Z. Tang, H. Yu, and M. Asano Degradation of origin recognition complex large subunit by the anaphase-promoting complex in Drosophila EMBO J 22 2003 6115 6126
    • (2003) EMBO J , vol.22 , pp. 6115-6126
    • Araki, M.1    Wharton, R.P.2    Tang, Z.3    Yu, H.4    Asano, M.5
  • 9
    • 48749117943 scopus 로고    scopus 로고
    • Multi-targeted therapy of cancer by genistein
    • S. Banerjee, Y. Li, Z. Wang, and F.H. Sarkar Multi-targeted therapy of cancer by genistein Cancer Lett 269 2008 226 242
    • (2008) Cancer Lett , vol.269 , pp. 226-242
    • Banerjee, S.1    Li, Y.2    Wang, Z.3    Sarkar, F.H.4
  • 10
    • 65849180296 scopus 로고    scopus 로고
    • DNA damage induced p53 downregulates Cdc20 by direct binding to its promoter causing chromatin remodeling
    • T. Banerjee, S. Nath, and S. Roychoudhury DNA damage induced p53 downregulates Cdc20 by direct binding to its promoter causing chromatin remodeling Nucleic Acids Res 37 2009 2688 2698
    • (2009) Nucleic Acids Res , vol.37 , pp. 2688-2698
    • Banerjee, T.1    Nath, S.2    Roychoudhury, S.3
  • 11
    • 1642378661 scopus 로고    scopus 로고
    • Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
    • T. Bashir, N.V. Dorrello, V. Amador, D. Guardavaccaro, and M. Pagano Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase Nature 428 2004 190 193
    • (2004) Nature , vol.428 , pp. 190-193
    • Bashir, T.1    Dorrello, N.V.2    Amador, V.3    Guardavaccaro, D.4    Pagano, M.5
  • 12
    • 84890243576 scopus 로고    scopus 로고
    • The ubiquitin proteasome system - Implications for cell cycle control and the targeted treatment of cancer
    • F. Bassermann, R. Eichner, and M. Pagano The ubiquitin proteasome system - implications for cell cycle control and the targeted treatment of cancer Biochim Biophys Acta 1843 2014 150 162
    • (2014) Biochim Biophys Acta , vol.1843 , pp. 150-162
    • Bassermann, F.1    Eichner, R.2    Pagano, M.3
  • 13
    • 84901649848 scopus 로고    scopus 로고
    • COX-2 inhibitors arrest prostate cancer cell cycle progression by down-regulation of kinetochore/centromere proteins
    • J. Bieniek, C. Childress, M.D. Swatski, and W. Yang COX-2 inhibitors arrest prostate cancer cell cycle progression by down-regulation of kinetochore/centromere proteins Prostate 74 2014 999 1011
    • (2014) Prostate , vol.74 , pp. 999-1011
    • Bieniek, J.1    Childress, C.2    Swatski, M.D.3    Yang, W.4
  • 14
    • 84861397625 scopus 로고    scopus 로고
    • Regulation of E2F1 by APC/C Cdh1 via K11 linkage-specific ubiquitin chain formation
    • V.N. Budhavarapu, E.D. White, C.S. Mahanic, L. Chen, F.T. Lin, and W.C. Lin Regulation of E2F1 by APC/C Cdh1 via K11 linkage-specific ubiquitin chain formation Cell Cycle 11 2012 2030 2038
    • (2012) Cell Cycle , vol.11 , pp. 2030-2038
    • Budhavarapu, V.N.1    White, E.D.2    Mahanic, C.S.3    Chen, L.4    Lin, F.T.5    Lin, W.C.6
  • 16
    • 0038317575 scopus 로고    scopus 로고
    • Xkid is degraded in a D-box, KEN-box, and A-box-independent pathway
    • A. Castro, S. Vigneron, C. Bernis, J.C. Labbe, and T. Lorca Xkid is degraded in a D-box, KEN-box, and A-box-independent pathway Mol Cell Biol 23 2003 4126 4138
    • (2003) Mol Cell Biol , vol.23 , pp. 4126-4138
    • Castro, A.1    Vigneron, S.2    Bernis, C.3    Labbe, J.C.4    Lorca, T.5
  • 17
    • 84906515478 scopus 로고    scopus 로고
    • Insights into the anaphase-promoting complex: A molecular machine that regulates mitosis
    • L. Chang, and D. Barford Insights into the anaphase-promoting complex: a molecular machine that regulates mitosis Curr Opin Struct Biol 29 2014 1 9
    • (2014) Curr Opin Struct Biol , vol.29 , pp. 1-9
    • Chang, L.1    Barford, D.2
  • 18
    • 84859193216 scopus 로고    scopus 로고
    • Increased CDC20 expression is associated with pancreatic ductal adenocarcinoma differentiation and progression
    • D.Z. Chang, Y. Ma, B. Ji, Y. Liu, P. Hwu, and J.L. Abbruzzese Increased CDC20 expression is associated with pancreatic ductal adenocarcinoma differentiation and progression J Hematol Oncol 5 2012 15
    • (2012) J Hematol Oncol , vol.5 , pp. 15
    • Chang, D.Z.1    Ma, Y.2    Ji, B.3    Liu, Y.4    Hwu, P.5    Abbruzzese, J.L.6
  • 19
    • 84906493054 scopus 로고    scopus 로고
    • Molecular architecture and mechanism of the anaphase-promoting complex
    • L. Chang, Z. Zhang, J. Yang, S.H. McLaughlin, and D. Barford Molecular architecture and mechanism of the anaphase-promoting complex Nature 513 2014 388 393
    • (2014) Nature , vol.513 , pp. 388-393
    • Chang, L.1    Zhang, Z.2    Yang, J.3    McLaughlin, S.H.4    Barford, D.5
  • 20
    • 77953534070 scopus 로고    scopus 로고
    • Functional roles of PC-PLC and Cdc20 in the cell cycle, proliferation, and apoptosis
    • Z. Chen, Y. Yu, D. Fu, Z. Li, X. Niu, and M. Liao Functional roles of PC-PLC and Cdc20 in the cell cycle, proliferation, and apoptosis Cell Biochem Funct 28 2010 249 257
    • (2010) Cell Biochem Funct , vol.28 , pp. 249-257
    • Chen, Z.1    Yu, Y.2    Fu, D.3    Li, Z.4    Niu, X.5    Liao, M.6
  • 21
    • 84861141712 scopus 로고    scopus 로고
    • Degradation of human RAP80 is cell cycle regulated by Cdc20 and Cdh1 ubiquitin ligases
    • H.J. Cho, E.H. Lee, S.H. Han, H.J. Chung, J.H. Jeong, and J. Kwon Degradation of human RAP80 is cell cycle regulated by Cdc20 and Cdh1 ubiquitin ligases Mol Cancer Res 10 2012 615 625
    • (2012) Mol Cancer Res , vol.10 , pp. 615-625
    • Cho, H.J.1    Lee, E.H.2    Han, S.H.3    Chung, H.J.4    Jeong, J.H.5    Kwon, J.6
  • 22
    • 84889089838 scopus 로고    scopus 로고
    • High expression of spindle assembly checkpoint proteins CDC20 and MAD2 is associated with poor prognosis in urothelial bladder cancer
    • J.W. Choi, Y. Kim, J.H. Lee, and Y.S. Kim High expression of spindle assembly checkpoint proteins CDC20 and MAD2 is associated with poor prognosis in urothelial bladder cancer Virchows Arch 463 2013 681 687
    • (2013) Virchows Arch , vol.463 , pp. 681-687
    • Choi, J.W.1    Kim, Y.2    Lee, J.H.3    Kim, Y.S.4
  • 23
    • 84873619237 scopus 로고    scopus 로고
    • REV7 is required for anaphase-promoting complex-dependent ubiquitination and degradation of translesion DNA polymerase REV1
    • A.C. Chun, K.H. Kok, and D.Y. Jin REV7 is required for anaphase-promoting complex-dependent ubiquitination and degradation of translesion DNA polymerase REV1 Cell Cycle 12 2013 365 378
    • (2013) Cell Cycle , vol.12 , pp. 365-378
    • Chun, A.C.1    Kok, K.H.2    Jin, D.Y.3
  • 24
    • 84880011165 scopus 로고    scopus 로고
    • The spindle checkpoint, APC/C(Cdc20), and APC/C(Cdh1) play distinct roles in connecting mitosis to S phase
    • L. Clijsters, J. Ogink, and R. Wolthuis The spindle checkpoint, APC/C(Cdc20), and APC/C(Cdh1) play distinct roles in connecting mitosis to S phase J Cell Biol 201 2013 1013 1026
    • (2013) J Cell Biol , vol.201 , pp. 1013-1026
    • Clijsters, L.1    Ogink, J.2    Wolthuis, R.3
  • 25
    • 0033145508 scopus 로고    scopus 로고
    • Temporal and spatial control of cyclin B1 destruction in metaphase
    • P. Clute, and J. Pines Temporal and spatial control of cyclin B1 destruction in metaphase Nat Cell Biol 1 1999 82 87
    • (1999) Nat Cell Biol , vol.1 , pp. 82-87
    • Clute, P.1    Pines, J.2
  • 26
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-or-death switch
    • S. Cory, and J.M. Adams The Bcl2 family: regulators of the cellular life-or-death switch Nat Rev Cancer 2 2002 647 656
    • (2002) Nat Rev Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 27
    • 65849378710 scopus 로고    scopus 로고
    • Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics
    • M.S. Cragg, C. Harris, A. Strasser, and C.L. Scott Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics Nat Rev Cancer 9 2009 321 326
    • (2009) Nat Rev Cancer , vol.9 , pp. 321-326
    • Cragg, M.S.1    Harris, C.2    Strasser, A.3    Scott, C.L.4
  • 28
    • 77958484246 scopus 로고    scopus 로고
    • Degradation of the human mitotic checkpoint kinase Mps1 is cell cycle-regulated by APC-cCdc20 and APC-cCdh1 ubiquitin ligases
    • Y. Cui, X. Cheng, C. Zhang, Y. Zhang, S. Li, and C. Wang Degradation of the human mitotic checkpoint kinase Mps1 is cell cycle-regulated by APC-cCdc20 and APC-cCdh1 ubiquitin ligases J Biol Chem 285 2010 32988 32998
    • (2010) J Biol Chem , vol.285 , pp. 32988-32998
    • Cui, Y.1    Cheng, X.2    Zhang, C.3    Zhang, Y.4    Li, S.5    Wang, C.6
  • 29
    • 84872728523 scopus 로고    scopus 로고
    • Forkhead box M1 is regulated by heat shock factor 1 and promotes glioma cells survival under heat shock stress
    • B. Dai, A. Gong, Z. Jing, K.D. Aldape, S.H. Kang, and R. Sawaya Forkhead box M1 is regulated by heat shock factor 1 and promotes glioma cells survival under heat shock stress J Biol Chem 288 2013 1634 1642
    • (2013) J Biol Chem , vol.288 , pp. 1634-1642
    • Dai, B.1    Gong, A.2    Jing, Z.3    Aldape, K.D.4    Kang, S.H.5    Sawaya, R.6
  • 30
    • 84905497126 scopus 로고    scopus 로고
    • Withaferin A modulates the Spindle assembly checkpoint by degradation of Mad2-Cdc20 complex in colorectal cancer cell lines
    • T. Das, K.S. Roy, T. Chakrabarti, S. Mukhopadhyay, and S. Roychoudhury Withaferin A modulates the Spindle assembly checkpoint by degradation of Mad2-Cdc20 complex in colorectal cancer cell lines Biochem Pharmacol 91 2014 31 39
    • (2014) Biochem Pharmacol , vol.91 , pp. 31-39
    • Das, T.1    Roy, K.S.2    Chakrabarti, T.3    Mukhopadhyay, S.4    Roychoudhury, S.5
  • 32
    • 0035795414 scopus 로고    scopus 로고
    • Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase
    • N. den Elzen, and J. Pines Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase J Cell Biol 153 2001 121 136
    • (2001) J Cell Biol , vol.153 , pp. 121-136
    • Den Elzen, N.1    Pines, J.2
  • 33
    • 84922794048 scopus 로고    scopus 로고
    • The ABBA motif binds APC/C activators and is shared by APC/C substrates and regulators
    • B. Di Fiore, N.E. Davey, A. Hagting, D. Izawa, J. Mansfeld, and T.J. Gibson The ABBA motif binds APC/C activators and is shared by APC/C substrates and regulators Dev Cell 32 2015 358 372
    • (2015) Dev Cell , vol.32 , pp. 358-372
    • Di Fiore, B.1    Davey, N.E.2    Hagting, A.3    Izawa, D.4    Mansfeld, J.5    Gibson, T.J.6
  • 34
    • 84894036102 scopus 로고    scopus 로고
    • Expression characteristics of CDC20 in gastric cancer and its correlation with poor prognosis
    • Z.Y. Ding, H.R. Wu, J.M. Zhang, G.R. Huang, and D.D. Ji Expression characteristics of CDC20 in gastric cancer and its correlation with poor prognosis Int J Clin Exp Pathol 7 2014 722 727
    • (2014) Int J Clin Exp Pathol , vol.7 , pp. 722-727
    • Ding, Z.Y.1    Wu, H.R.2    Zhang, J.M.3    Huang, G.R.4    Ji, D.D.5
  • 35
    • 84907362479 scopus 로고    scopus 로고
    • Overview of proteasome inhibitor-based anti-cancer therapies: Perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system
    • Q.P. Dou, and J.A. Zonder Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system Curr Cancer Drug Targets 14 2014 517 536
    • (2014) Curr Cancer Drug Targets , vol.14 , pp. 517-536
    • Dou, Q.P.1    Zonder, J.A.2
  • 36
    • 0032525783 scopus 로고    scopus 로고
    • The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation
    • G. Fang, H. Yu, and M.W. Kirschner The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation Genes Dev 12 1998 1871 1883
    • (1998) Genes Dev , vol.12 , pp. 1871-1883
    • Fang, G.1    Yu, H.2    Kirschner, M.W.3
  • 37
    • 79951470147 scopus 로고    scopus 로고
    • Structural biology: A new look for the APC
    • I. Foe, and D. Toczyski Structural biology: a new look for the APC Nature 470 2011 182 183
    • (2011) Nature , vol.470 , pp. 182-183
    • Foe, I.1    Toczyski, D.2
  • 38
    • 0033620688 scopus 로고    scopus 로고
    • Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2
    • R. Fraschini, E. Formenti, G. Lucchini, and S. Piatti Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2 J Cell Biol 145 1999 979 991
    • (1999) J Cell Biol , vol.145 , pp. 979-991
    • Fraschini, R.1    Formenti, E.2    Lucchini, G.3    Piatti, S.4
  • 39
    • 67749145231 scopus 로고    scopus 로고
    • Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways
    • D. Gao, H. Inuzuka, M. Korenjak, A. Tseng, T. Wu, and L. Wan Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways Mol Biol Cell 20 2009 3305 3316
    • (2009) Mol Biol Cell , vol.20 , pp. 3305-3316
    • Gao, D.1    Inuzuka, H.2    Korenjak, M.3    Tseng, A.4    Wu, T.5    Wan, L.6
  • 40
    • 0035795408 scopus 로고    scopus 로고
    • Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint
    • S. Geley, E. Kramer, C. Gieffers, J. Gannon, J.M. Peters, and T. Hunt Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint J Cell Biol 153 2001 137 148
    • (2001) J Cell Biol , vol.153 , pp. 137-148
    • Geley, S.1    Kramer, E.2    Gieffers, C.3    Gannon, J.4    Peters, J.M.5    Hunt, T.6
  • 41
    • 76649137590 scopus 로고    scopus 로고
    • Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F
    • M.D. Gurden, A.J. Holland, W. van Zon, A. Tighe, M.A. Vergnolle, and D.A. Andres Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F J Cell Sci 123 2010 321 330
    • (2010) J Cell Sci , vol.123 , pp. 321-330
    • Gurden, M.D.1    Holland, A.J.2    Van Zon, W.3    Tighe, A.4    Vergnolle, M.A.5    Andres, D.A.6
  • 42
    • 84859420605 scopus 로고    scopus 로고
    • Cell cycle control of Wnt/beta-catenin signalling by conductin/axin2 through CDC20
    • M.V. Hadjihannas, D.B. Bernkopf, M. Bruckner, and J. Behrens Cell cycle control of Wnt/beta-catenin signalling by conductin/axin2 through CDC20 EMBO Rep 13 2012 347 354
    • (2012) EMBO Rep , vol.13 , pp. 347-354
    • Hadjihannas, M.V.1    Bernkopf, D.B.2    Bruckner, M.3    Behrens, J.4
  • 43
    • 0037126610 scopus 로고    scopus 로고
    • APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box
    • R.S. Hames, S.L. Wattam, H. Yamano, R. Bacchieri, and A.M. Fry APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box EMBO J 20 2001 7117 7127
    • (2001) EMBO J , vol.20 , pp. 7117-7127
    • Hames, R.S.1    Wattam, S.L.2    Yamano, H.3    Bacchieri, R.4    Fry, A.M.5
  • 44
    • 77954884045 scopus 로고    scopus 로고
    • Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest
    • M.E. Harley, L.A. Allan, H.S. Sanderson, and P.R. Clarke Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest EMBO J 29 2010 2407 2420
    • (2010) EMBO J , vol.29 , pp. 2407-2420
    • Harley, M.E.1    Allan, L.A.2    Sanderson, H.S.3    Clarke, P.R.4
  • 45
    • 0014804012 scopus 로고
    • Genetic control of the cell-division cycle in yeast. I. Detection of mutants
    • L.H. Hartwell, J. Culotti, and B. Reid Genetic control of the cell-division cycle in yeast. I. Detection of mutants Proc Natl Acad Sci U S A 66 1970 352 359
    • (1970) Proc Natl Acad Sci U S A , vol.66 , pp. 352-359
    • Hartwell, L.H.1    Culotti, J.2    Reid, B.3
  • 46
    • 0015847513 scopus 로고
    • Genetic control of the cell division cycle in yeast: V. Genetic analysis of CDC mutants
    • L.H. Hartwell, R.K. Mortimer, J. Culotti, and M. Culotti Genetic control of the cell division cycle in yeast: v. genetic analysis of CDC mutants Genetics 74 1973 267 286
    • (1973) Genetics , vol.74 , pp. 267-286
    • Hartwell, L.H.1    Mortimer, R.K.2    Culotti, J.3    Culotti, M.4
  • 47
    • 33744813542 scopus 로고    scopus 로고
    • Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C
    • M.J. Hayes, Y. Kimata, S.L. Wattam, C. Lindon, G. Mao, and H. Yamano Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C Nat Cell Biol 8 2006 607 614
    • (2006) Nat Cell Biol , vol.8 , pp. 607-614
    • Hayes, M.J.1    Kimata, Y.2    Wattam, S.L.3    Lindon, C.4    Mao, G.5    Yamano, H.6
  • 48
    • 33748991453 scopus 로고    scopus 로고
    • Ubiquitin and ubiquitin-like proteins in cancer pathogenesis
    • D. Hoeller, C.M. Hecker, and I. Dikic Ubiquitin and ubiquitin-like proteins in cancer pathogenesis Nat Rev Cancer 6 2006 776 788
    • (2006) Nat Rev Cancer , vol.6 , pp. 776-788
    • Hoeller, D.1    Hecker, C.M.2    Dikic, I.3
  • 49
    • 80054741159 scopus 로고    scopus 로고
    • The emerging role of APC/CCdh1 in development
    • D. Hu, X. Qiao, G. Wu, and Y. Wan The emerging role of APC/CCdh1 in development Semin Cell Dev Biol 22 2011 579 585
    • (2011) Semin Cell Dev Biol , vol.22 , pp. 579-585
    • Hu, D.1    Qiao, X.2    Wu, G.3    Wan, Y.4
  • 50
    • 70349452101 scopus 로고    scopus 로고
    • Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly
    • H.C. Huang, J. Shi, J.D. Orth, and T.J. Mitchison Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly Cancer Cell 16 2009 347 358
    • (2009) Cancer Cell , vol.16 , pp. 347-358
    • Huang, H.C.1    Shi, J.2    Orth, J.D.3    Mitchison, T.J.4
  • 51
    • 84891933728 scopus 로고    scopus 로고
    • The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle
    • G. Ichim, M. Mola, M.G. Finkbeiner, M.P. Cros, Z. Herceg, and H. Hernandez-Vargas The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle Oncogene 33 2014 181 192
    • (2014) Oncogene , vol.33 , pp. 181-192
    • Ichim, G.1    Mola, M.2    Finkbeiner, M.G.3    Cros, M.P.4    Herceg, Z.5    Hernandez-Vargas, H.6
  • 52
    • 84922786545 scopus 로고    scopus 로고
    • The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C
    • D. Izawa, and J. Pines The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C Nature 517 2015 631 634
    • (2015) Nature , vol.517 , pp. 631-634
    • Izawa, D.1    Pines, J.2
  • 53
    • 84921282213 scopus 로고    scopus 로고
    • Withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-kappaB signaling
    • S.S. Jackson, C. Oberley, C.P. Hooper, K. Grindle, S. Wuerzberger-Davis, and J. Wolff Withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-kappaB signaling Exp Cell Res 331 2015 58 72
    • (2015) Exp Cell Res , vol.331 , pp. 58-72
    • Jackson, S.S.1    Oberley, C.2    Hooper, C.P.3    Grindle, K.4    Wuerzberger-Davis, S.5    Wolff, J.6
  • 54
    • 84897143170 scopus 로고    scopus 로고
    • CARP-1 functional mimetics are a novel class of small molecule inhibitors of malignant pleural mesothelioma cells
    • S. Jamal, V.T. Cheriyan, M. Muthu, S. Munie, E. Levi, and A.E. Ashour CARP-1 functional mimetics are a novel class of small molecule inhibitors of malignant pleural mesothelioma cells PLoS One 9 2014 e89146
    • (2014) PLoS One , vol.9 , pp. e89146
    • Jamal, S.1    Cheriyan, V.T.2    Muthu, M.3    Munie, S.4    Levi, E.5    Ashour, A.E.6
  • 55
    • 79959684880 scopus 로고    scopus 로고
    • Mitosis as an anti-cancer target
    • A. Janssen, and R.H. Medema Mitosis as an anti-cancer target Oncogene 30 2011 2799 2809
    • (2011) Oncogene , vol.30 , pp. 2799-2809
    • Janssen, A.1    Medema, R.H.2
  • 56
    • 77953792438 scopus 로고    scopus 로고
    • Inhibition of gliomagenesis and attenuation of mitotic transition by MIIP
    • P. Ji, S.M. Smith, Y. Wang, R. Jiang, S.W. Song, and B. Li Inhibition of gliomagenesis and attenuation of mitotic transition by MIIP Oncogene 29 2010 3501 3508
    • (2010) Oncogene , vol.29 , pp. 3501-3508
    • Ji, P.1    Smith, S.M.2    Wang, Y.3    Jiang, R.4    Song, S.W.5    Li, B.6
  • 57
    • 84855871486 scopus 로고    scopus 로고
    • Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPA
    • J. Jiang, A. Jedinak, and D. Sliva Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPA Biochem Biophys Res Commun 415 2011 325 329
    • (2011) Biochem Biophys Res Commun , vol.415 , pp. 325-329
    • Jiang, J.1    Jedinak, A.2    Sliva, D.3
  • 58
    • 78649918823 scopus 로고    scopus 로고
    • Novel medicinal mushroom blend suppresses growth and invasiveness of human breast cancer cells
    • J. Jiang, and D. Sliva Novel medicinal mushroom blend suppresses growth and invasiveness of human breast cancer cells Int J Oncol 37 2010 1529 1536
    • (2010) Int J Oncol , vol.37 , pp. 1529-1536
    • Jiang, J.1    Sliva, D.2
  • 59
    • 84859021896 scopus 로고    scopus 로고
    • NAHA, a novel hydroxamic acid-derivative, inhibits growth and angiogenesis of breast cancer in vitro and in vivo
    • J. Jiang, A. Thyagarajan-Sahu, V. Krchnak, A. Jedinak, G.E. Sandusky, and D. Sliva NAHA, a novel hydroxamic acid-derivative, inhibits growth and angiogenesis of breast cancer in vitro and in vivo PLoS One 7 2012 e34283
    • (2012) PLoS One , vol.7 , pp. e34283
    • Jiang, J.1    Thyagarajan-Sahu, A.2    Krchnak, V.3    Jedinak, A.4    Sandusky, G.E.5    Sliva, D.6
  • 60
    • 43049162227 scopus 로고    scopus 로고
    • Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex
    • L. Jin, A. Williamson, S. Banerjee, I. Philipp, and M. Rape Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex Cell 133 2008 653 665
    • (2008) Cell , vol.133 , pp. 653-665
    • Jin, L.1    Williamson, A.2    Banerjee, S.3    Philipp, I.4    Rape, M.5
  • 61
    • 84907500419 scopus 로고    scopus 로고
    • Withaferin a alone and in combination with Cisplatin suppresses growth and metastasis of ovarian cancer by targeting putative cancer stem cells
    • S.S. Kakar, M.Z. Ratajczak, K.S. Powell, M. Moghadamfalahi, D.M. Miller, and S.K. Batra Withaferin a alone and in combination with Cisplatin suppresses growth and metastasis of ovarian cancer by targeting putative cancer stem cells PLoS One 9 2014 e107596
    • (2014) PLoS One , vol.9 , pp. e107596
    • Kakar, S.S.1    Ratajczak, M.Z.2    Powell, K.S.3    Moghadamfalahi, M.4    Miller, D.M.5    Batra, S.K.6
  • 62
  • 63
    • 84865135210 scopus 로고    scopus 로고
    • Overexpression of CDC20 predicts poor prognosis in primary non-small cell lung cancer patients
    • T. Kato, Y. Daigo, M. Aragaki, K. Ishikawa, M. Sato, and M. Kaji Overexpression of CDC20 predicts poor prognosis in primary non-small cell lung cancer patients J Surg Oncol 106 2012 423 430
    • (2012) J Surg Oncol , vol.106 , pp. 423-430
    • Kato, T.1    Daigo, Y.2    Aragaki, M.3    Ishikawa, K.4    Sato, M.5    Kaji, M.6
  • 65
    • 84906047014 scopus 로고    scopus 로고
    • MAD2 and CDC20 are upregulated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the uterine cervix
    • Y. Kim, J.W. Choi, J.H. Lee, and Y.S. Kim MAD2 and CDC20 are upregulated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the uterine cervix Int J Gynecol Pathol 33 2014 517 523
    • (2014) Int J Gynecol Pathol , vol.33 , pp. 517-523
    • Kim, Y.1    Choi, J.W.2    Lee, J.H.3    Kim, Y.S.4
  • 66
    • 58249112141 scopus 로고    scopus 로고
    • Functional interaction between BubR1 and securin in an anaphase-promoting complex/cyclosomeCdc20-independent manner
    • H.S. Kim, Y.K. Jeon, G.H. Ha, H.Y. Park, Y.J. Kim, and H.J. Shin Functional interaction between BubR1 and securin in an anaphase-promoting complex/cyclosomeCdc20-independent manner Cancer Res 69 2009 27 36
    • (2009) Cancer Res , vol.69 , pp. 27-36
    • Kim, H.S.1    Jeon, Y.K.2    Ha, G.H.3    Park, H.Y.4    Kim, Y.J.5    Shin, H.J.6
  • 67
    • 58249091452 scopus 로고    scopus 로고
    • A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons
    • A.H. Kim, S.V. Puram, P.M. Bilimoria, Y. Ikeuchi, S. Keough, and M. Wong A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons Cell 136 2009 322 336
    • (2009) Cell , vol.136 , pp. 322-336
    • Kim, A.H.1    Puram, S.V.2    Bilimoria, P.M.3    Ikeuchi, Y.4    Keough, S.5    Wong, M.6
  • 68
    • 19944425959 scopus 로고    scopus 로고
    • Identification of gastric cancer-related genes using a cDNA microarray containing novel expressed sequence tags expressed in gastric cancer cells
    • J.M. Kim, H.Y. Sohn, S.Y. Yoon, J.H. Oh, J.O. Yang, and J.H. Kim Identification of gastric cancer-related genes using a cDNA microarray containing novel expressed sequence tags expressed in gastric cancer cells Clin Cancer Res 11 2005 473 482
    • (2005) Clin Cancer Res , vol.11 , pp. 473-482
    • Kim, J.M.1    Sohn, H.Y.2    Yoon, S.Y.3    Oh, J.H.4    Yang, J.O.5    Kim, J.H.6
  • 69
    • 80054769188 scopus 로고    scopus 로고
    • SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity
    • H.S. Kim, A. Vassilopoulos, R.H. Wang, T. Lahusen, Z. Xiao, and X. Xu SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity Cancer Cell 20 2011 487 499
    • (2011) Cancer Cell , vol.20 , pp. 487-499
    • Kim, H.S.1    Vassilopoulos, A.2    Wang, R.H.3    Lahusen, T.4    Xiao, Z.5    Xu, X.6
  • 70
    • 80054758730 scopus 로고    scopus 로고
    • Mutual regulation between the spindle checkpoint and APC/C
    • S. Kim, and H. Yu Mutual regulation between the spindle checkpoint and APC/C Semin Cell Dev Biol 22 2011 551 558
    • (2011) Semin Cell Dev Biol , vol.22 , pp. 551-558
    • Kim, S.1    Yu, H.2
  • 71
    • 84874647348 scopus 로고    scopus 로고
    • Colorectal cancer screening - Optimizing current strategies and new directions
    • E.J. Kuipers, T. Rosch, and M. Bretthauer Colorectal cancer screening - optimizing current strategies and new directions Nat Rev Clin Oncol 10 2013 130 142
    • (2013) Nat Rev Clin Oncol , vol.10 , pp. 130-142
    • Kuipers, E.J.1    Rosch, T.2    Bretthauer, M.3
  • 73
    • 84875912456 scopus 로고    scopus 로고
    • Daxx regulates mitotic progression and prostate cancer predisposition
    • P.S. Kwan, C.C. Lau, Y.T. Chiu, C. Man, J. Liu, and K.D. Tang Daxx regulates mitotic progression and prostate cancer predisposition Carcinogenesis 34 2013 750 759
    • (2013) Carcinogenesis , vol.34 , pp. 750-759
    • Kwan, P.S.1    Lau, C.C.2    Chiu, Y.T.3    Man, C.4    Liu, J.5    Tang, K.D.6
  • 74
    • 84860496378 scopus 로고    scopus 로고
    • The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis
    • A.W. Lau, H. Fukushima, and W. Wei The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis Front Biosci 17 2012 2197 2212
    • (2012) Front Biosci , vol.17 , pp. 2197-2212
    • Lau, A.W.1    Fukushima, H.2    Wei, W.3
  • 75
    • 84907457916 scopus 로고    scopus 로고
    • Increased CDC20 expression is associated with development and progression of hepatocellular carcinoma
    • J. Li, J.Z. Gao, J.L. Du, Z.X. Huang, and L.X. Wei Increased CDC20 expression is associated with development and progression of hepatocellular carcinoma Int J Oncol 45 2014 1547 1555
    • (2014) Int J Oncol , vol.45 , pp. 1547-1555
    • Li, J.1    Gao, J.Z.2    Du, J.L.3    Huang, Z.X.4    Wei, L.X.5
  • 76
    • 34247635494 scopus 로고    scopus 로고
    • Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos
    • M. Li, J.P. York, and P. Zhang Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos Mol Cell Biol 27 2007 3481 3488
    • (2007) Mol Cell Biol , vol.27 , pp. 3481-3488
    • Li, M.1    York, J.P.2    Zhang, P.3
  • 77
    • 0037343237 scopus 로고    scopus 로고
    • Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer
    • D. Li, J. Zhu, P.F. Firozi, J.L. Abbruzzese, D.B. Evans, and K. Cleary Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer Clin Cancer Res 9 2003 991 997
    • (2003) Clin Cancer Res , vol.9 , pp. 991-997
    • Li, D.1    Zhu, J.2    Firozi, P.F.3    Abbruzzese, J.L.4    Evans, D.B.5    Cleary, K.6
  • 78
    • 84920496306 scopus 로고    scopus 로고
    • Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells
    • X. Li, F. Zhu, J. Jiang, C. Sun, X. Wang, and M. Shen Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells Cancer Lett 357 2015 219 230
    • (2015) Cancer Lett , vol.357 , pp. 219-230
    • Li, X.1    Zhu, F.2    Jiang, J.3    Sun, C.4    Wang, X.5    Shen, M.6
  • 79
    • 84886926638 scopus 로고    scopus 로고
    • The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20
    • H.J. Lim, N.V. Dimova, M.K. Tan, F.D. Sigoillot, R.W. King, and Y. Shi The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20 Mol Cell Biol 33 2013 4166 4180
    • (2013) Mol Cell Biol , vol.33 , pp. 4166-4180
    • Lim, H.J.1    Dimova, N.V.2    Tan, M.K.3    Sigoillot, F.D.4    King, R.W.5    Shi, Y.6
  • 80
    • 0001598759 scopus 로고    scopus 로고
    • Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast
    • H.H. Lim, P.Y. Goh, and U. Surana Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast Curr Biol 8 1998 231 234
    • (1998) Curr Biol , vol.8 , pp. 231-234
    • Lim, H.H.1    Goh, P.Y.2    Surana, U.3
  • 81
    • 1642458099 scopus 로고    scopus 로고
    • Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells
    • C. Lindon, and J. Pines Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells J Cell Biol 164 2004 233 241
    • (2004) J Cell Biol , vol.164 , pp. 233-241
    • Lindon, C.1    Pines, J.2
  • 82
    • 80052069445 scopus 로고    scopus 로고
    • RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis
    • S. Lipkowitz, and A.M. Weissman RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis Nat Rev Cancer 11 2011 629 643
    • (2011) Nat Rev Cancer , vol.11 , pp. 629-643
    • Lipkowitz, S.1    Weissman, A.M.2
  • 83
    • 0036714512 scopus 로고    scopus 로고
    • Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit
    • L.E. Littlepage, and J.V. Ruderman Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit Genes Dev 16 2002 2274 2285
    • (2002) Genes Dev , vol.16 , pp. 2274-2285
    • Littlepage, L.E.1    Ruderman, J.V.2
  • 84
    • 78649846540 scopus 로고    scopus 로고
    • MicroRNA-449a levels increase by several orders of magnitude during mucociliary differentiation of airway epithelia
    • M. Lize, C. Herr, A. Klimke, R. Bals, and M. Dobbelstein MicroRNA-449a levels increase by several orders of magnitude during mucociliary differentiation of airway epithelia Cell Cycle 9 2010 4579 4583
    • (2010) Cell Cycle , vol.9 , pp. 4579-4583
    • Lize, M.1    Herr, C.2    Klimke, A.3    Bals, R.4    Dobbelstein, M.5
  • 86
    • 84896744316 scopus 로고    scopus 로고
    • Inhibiting tumor growth by targeting liposomally encapsulated CDC20siRNA to tumor vasculature: Therapeutic RNA interference
    • P. Majumder, S. Bhunia, J. Bhattacharyya, and A. Chaudhuri Inhibiting tumor growth by targeting liposomally encapsulated CDC20siRNA to tumor vasculature: therapeutic RNA interference J Control Release 180 2014 100 108
    • (2014) J Control Release , vol.180 , pp. 100-108
    • Majumder, P.1    Bhunia, S.2    Bhattacharyya, J.3    Chaudhuri, A.4
  • 87
    • 78650004841 scopus 로고    scopus 로고
    • Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55alpha, delta phosphatase
    • E. Manchado, M. Guillamot, G. de Carcer, M. Eguren, M. Trickey, and I. Garcia-Higuera Targeting mitotic exit leads to tumor regression in vivo: modulation by Cdk1, Mastl, and the PP2A/B55alpha, delta phosphatase Cancer Cell 18 2010 641 654
    • (2010) Cancer Cell , vol.18 , pp. 641-654
    • Manchado, E.1    Guillamot, M.2    De Carcer, G.3    Eguren, M.4    Trickey, M.5    Garcia-Higuera, I.6
  • 88
    • 55849100002 scopus 로고    scopus 로고
    • Gene expression profiling in glioblastoma and immunohistochemical evaluation of IGFBP-2 and CDC20
    • G. Marucci, L. Morandi, E. Magrini, A. Farnedi, E. Franceschi, and R. Miglio Gene expression profiling in glioblastoma and immunohistochemical evaluation of IGFBP-2 and CDC20 Virchows Arch 453 2008 599 609
    • (2008) Virchows Arch , vol.453 , pp. 599-609
    • Marucci, G.1    Morandi, L.2    Magrini, E.3    Farnedi, A.4    Franceschi, E.5    Miglio, R.6
  • 89
    • 0032511148 scopus 로고    scopus 로고
    • Geminin, an inhibitor of DNA replication, is degraded during mitosis
    • T.J. McGarry, and M.W. Kirschner Geminin, an inhibitor of DNA replication, is degraded during mitosis Cell 93 1998 1043 1053
    • (1998) Cell , vol.93 , pp. 1043-1053
    • McGarry, T.J.1    Kirschner, M.W.2
  • 91
    • 0030885925 scopus 로고    scopus 로고
    • Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids
    • C. Michaelis, R. Ciosk, and K. Nasmyth Cohesins: chromosomal proteins that prevent premature separation of sister chromatids Cell 91 1997 35 45
    • (1997) Cell , vol.91 , pp. 35-45
    • Michaelis, C.1    Ciosk, R.2    Nasmyth, K.3
  • 92
    • 33845657904 scopus 로고    scopus 로고
    • Overexpression of Cdc20 leads to impairment of the spindle assembly checkpoint and aneuploidization in oral cancer
    • G. Mondal, S. Sengupta, C.K. Panda, S.M. Gollin, W.S. Saunders, and S. Roychoudhury Overexpression of Cdc20 leads to impairment of the spindle assembly checkpoint and aneuploidization in oral cancer Carcinogenesis 28 2007 81 92
    • (2007) Carcinogenesis , vol.28 , pp. 81-92
    • Mondal, G.1    Sengupta, S.2    Panda, C.K.3    Gollin, S.M.4    Saunders, W.S.5    Roychoudhury, S.6
  • 94
    • 84883781728 scopus 로고    scopus 로고
    • BimEL is phosphorylated at mitosis by Aurora A and targeted for degradation by betaTrCP1
    • M. Moustafa-Kamal, I. Gamache, Y. Lu, S. Li, and J.G. Teodoro BimEL is phosphorylated at mitosis by Aurora A and targeted for degradation by betaTrCP1 Cell Death Differ 20 2013 1393 1403
    • (2013) Cell Death Differ , vol.20 , pp. 1393-1403
    • Moustafa-Kamal, M.1    Gamache, I.2    Lu, Y.3    Li, S.4    Teodoro, J.G.5
  • 95
    • 84900027779 scopus 로고    scopus 로고
    • Mechanistic elucidation of the antitumor properties of withaferin a in breast cancer
    • A. Nagalingam, P. Kuppusamy, S.V. Singh, D. Sharma, and N.K. Saxena Mechanistic elucidation of the antitumor properties of withaferin a in breast cancer Cancer Res 74 2014 2617 2629
    • (2014) Cancer Res , vol.74 , pp. 2617-2629
    • Nagalingam, A.1    Kuppusamy, P.2    Singh, S.V.3    Sharma, D.4    Saxena, N.K.5
  • 96
    • 33646345376 scopus 로고    scopus 로고
    • Ubiquitin ligases: Cell-cycle control and cancer
    • K.I. Nakayama, and K. Nakayama Ubiquitin ligases: cell-cycle control and cancer Nat Rev Cancer 6 2006 369 381
    • (2006) Nat Rev Cancer , vol.6 , pp. 369-381
    • Nakayama, K.I.1    Nakayama, K.2
  • 97
    • 0035678054 scopus 로고    scopus 로고
    • Disseminating the genome: Joining, resolving, and separating sister chromatids during mitosis and meiosis
    • K. Nasmyth Disseminating the genome: joining, resolving, and separating sister chromatids during mitosis and meiosis Annu Rev Genet 35 2001 673 745
    • (2001) Annu Rev Genet , vol.35 , pp. 673-745
    • Nasmyth, K.1
  • 98
    • 84897544142 scopus 로고    scopus 로고
    • Anticancer activity of new coumarin substituted hydrazide-hydrazone derivatives
    • T. Nasr, S. Bondock, and M. Youns Anticancer activity of new coumarin substituted hydrazide-hydrazone derivatives Eur J Med Chem 76 2014 539 548
    • (2014) Eur J Med Chem , vol.76 , pp. 539-548
    • Nasr, T.1    Bondock, S.2    Youns, M.3
  • 99
    • 0034673282 scopus 로고    scopus 로고
    • Human p55(CDC)/Cdc20 associates with cyclin A and is phosphorylated by the cyclin A-Cdk2 complex
    • A. Ohtoshi, T. Maeda, H. Higashi, S. Ashizawa, and M. Hatakeyama Human p55(CDC)/Cdc20 associates with cyclin A and is phosphorylated by the cyclin A-Cdk2 complex Biochem Biophys Res Commun 268 2000 530 534
    • (2000) Biochem Biophys Res Commun , vol.268 , pp. 530-534
    • Ohtoshi, A.1    Maeda, T.2    Higashi, H.3    Ashizawa, S.4    Hatakeyama, M.5
  • 100
    • 84891492954 scopus 로고    scopus 로고
    • The APC/C ubiquitin ligase: From cell biology to tumorigenesis
    • C. Penas, V. Ramachandran, and N.G. Ayad The APC/C ubiquitin ligase: from cell biology to tumorigenesis Front Oncol 1 2011 60
    • (2011) Front Oncol , vol.1 , pp. 60
    • Penas, C.1    Ramachandran, V.2    Ayad, N.G.3
  • 102
    • 80055065140 scopus 로고    scopus 로고
    • Antagonists of anaphase-promoting complex (APC)-2-cell cycle and apoptosis regulatory protein (CARP)-1 interaction are novel regulators of cell growth and apoptosis
    • V.T. Puliyappadamba, W. Wu, D. Bevis, L. Zhang, L. Polin, and R. Kilkuskie Antagonists of anaphase-promoting complex (APC)-2-cell cycle and apoptosis regulatory protein (CARP)-1 interaction are novel regulators of cell growth and apoptosis J Biol Chem 286 2011 38000 38017
    • (2011) J Biol Chem , vol.286 , pp. 38000-38017
    • Puliyappadamba, V.T.1    Wu, W.2    Bevis, D.3    Zhang, L.4    Polin, L.5    Kilkuskie, R.6
  • 103
    • 77958465476 scopus 로고    scopus 로고
    • APC/C-Cdh1: From cell cycle to cellular differentiation and genomic integrity
    • X. Qiao, L. Zhang, A.M. Gamper, T. Fujita, and Y. Wan APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity Cell Cycle 9 2010 3904 3912
    • (2010) Cell Cycle , vol.9 , pp. 3904-3912
    • Qiao, X.1    Zhang, L.2    Gamper, A.M.3    Fujita, T.4    Wan, Y.5
  • 105
    • 70349368602 scopus 로고    scopus 로고
    • The molecular basis of genistein-induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines
    • C.R. Regenbrecht, M. Jung, H. Lehrach, and J. Adjaye The molecular basis of genistein-induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines BMC Med Genomics 1 2008 49
    • (2008) BMC Med Genomics , vol.1 , pp. 49
    • Regenbrecht, C.R.1    Jung, M.2    Lehrach, H.3    Adjaye, J.4
  • 106
    • 0035370009 scopus 로고    scopus 로고
    • Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex
    • J.D. Reimann, E. Freed, J.Y. Hsu, E.R. Kramer, J.M. Peters, and P.K. Jackson Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex Cell 105 2001 645 655
    • (2001) Cell , vol.105 , pp. 645-655
    • Reimann, J.D.1    Freed, E.2    Hsu, J.Y.3    Kramer, E.R.4    Peters, J.M.5    Jackson, P.K.6
  • 107
    • 0035893917 scopus 로고    scopus 로고
    • Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins
    • J.D. Reimann, B.E. Gardner, F. Margottin-Goguet, and P.K. Jackson Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins Genes Dev 15 2001 3278 3285
    • (2001) Genes Dev , vol.15 , pp. 3278-3285
    • Reimann, J.D.1    Gardner, B.E.2    Margottin-Goguet, F.3    Jackson, P.K.4
  • 108
    • 33749243774 scopus 로고    scopus 로고
    • The CRY box: A second APCcdh1-dependent degron in mammalian cdc20
    • A. Reis, M. Levasseur, H.Y. Chang, D.J. Elliott, and K.T. Jones The CRY box: a second APCcdh1-dependent degron in mammalian cdc20 EMBO Rep 7 2006 1040 1045
    • (2006) EMBO Rep , vol.7 , pp. 1040-1045
    • Reis, A.1    Levasseur, M.2    Chang, H.Y.3    Elliott, D.J.4    Jones, K.T.5
  • 109
    • 84908408865 scopus 로고    scopus 로고
    • Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C
    • K.L. Sackton, N. Dimova, X. Zeng, W. Tian, M. Zhang, and T.B. Sackton Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C Nature 514 2014 646 649
    • (2014) Nature , vol.514 , pp. 646-649
    • Sackton, K.L.1    Dimova, N.2    Zeng, X.3    Tian, W.4    Zhang, M.5    Sackton, T.B.6
  • 110
    • 33646551734 scopus 로고    scopus 로고
    • The role of genistein and synthetic derivatives of isoflavone in cancer prevention and therapy
    • F.H. Sarkar, S. Adsule, S. Padhye, S. Kulkarni, and Y. Li The role of genistein and synthetic derivatives of isoflavone in cancer prevention and therapy Mini Rev Med Chem 6 2006 401 407
    • (2006) Mini Rev Med Chem , vol.6 , pp. 401-407
    • Sarkar, F.H.1    Adsule, S.2    Padhye, S.3    Kulkarni, S.4    Li, Y.5
  • 111
    • 77953497158 scopus 로고    scopus 로고
    • Lesson learned from nature for the development of novel anti-cancer agents: Implication of isoflavone, curcumin, and their synthetic analogs
    • F.H. Sarkar, Y. Li, Z. Wang, and S. Padhye Lesson learned from nature for the development of novel anti-cancer agents: implication of isoflavone, curcumin, and their synthetic analogs Curr Pharm Des 16 2010 1801 1812
    • (2010) Curr Pharm des , vol.16 , pp. 1801-1812
    • Sarkar, F.H.1    Li, Y.2    Wang, Z.3    Padhye, S.4
  • 112
    • 79951505095 scopus 로고    scopus 로고
    • Structural basis for the subunit assembly of the anaphase-promoting complex
    • A. Schreiber, F. Stengel, Z. Zhang, R.I. Enchev, E.H. Kong, and E.P. Morris Structural basis for the subunit assembly of the anaphase-promoting complex Nature 470 2011 227 232
    • (2011) Nature , vol.470 , pp. 227-232
    • Schreiber, A.1    Stengel, F.2    Zhang, Z.3    Enchev, R.I.4    Kong, E.H.5    Morris, E.P.6
  • 113
    • 84872849589 scopus 로고    scopus 로고
    • Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex
    • G.G. Sedgwick, D.G. Hayward, B. Di Fiore, M. Pardo, L. Yu, and J. Pines Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex EMBO J 32 2013 303 314
    • (2013) EMBO J , vol.32 , pp. 303-314
    • Sedgwick, G.G.1    Hayward, D.G.2    Di Fiore, B.3    Pardo, M.4    Yu, L.5    Pines, J.6
  • 114
    • 42049111856 scopus 로고    scopus 로고
    • The mammalian Nek1 kinase is involved in primary cilium formation
    • O. Shalom, N. Shalva, Y. Altschuler, and B. Motro The mammalian Nek1 kinase is involved in primary cilium formation FEBS Lett 582 2008 1465 1470
    • (2008) FEBS Lett , vol.582 , pp. 1465-1470
    • Shalom, O.1    Shalva, N.2    Altschuler, Y.3    Motro, B.4
  • 115
    • 84929464325 scopus 로고    scopus 로고
    • The effects of soy supplementation on gene expression in breast cancer: A randomized placebo-controlled study
    • M. Shike, A.S. Doane, L. Russo, R. Cabal, J. Reis-Filo, and W. Gerald The effects of soy supplementation on gene expression in breast cancer: a randomized placebo-controlled study J Natl Cancer Inst 106 2014
    • (2014) J Natl Cancer Inst , vol.106
    • Shike, M.1    Doane, A.S.2    Russo, L.3    Cabal, R.4    Reis-Filo, J.5    Gerald, W.6
  • 116
    • 0344578064 scopus 로고    scopus 로고
    • APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5
    • M. Shirayama, A. Toth, M. Galova, and K. Nasmyth APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5 Nature 402 1999 203 207
    • (1999) Nature , vol.402 , pp. 203-207
    • Shirayama, M.1    Toth, A.2    Galova, M.3    Nasmyth, K.4
  • 119
    • 77951949971 scopus 로고    scopus 로고
    • Regulated degradation of spindle assembly factors by the anaphase-promoting complex
    • L. Song, and M. Rape Regulated degradation of spindle assembly factors by the anaphase-promoting complex Mol Cell 38 2010 369 382
    • (2010) Mol Cell , vol.38 , pp. 369-382
    • Song, L.1    Rape, M.2
  • 120
    • 1642602695 scopus 로고    scopus 로고
    • The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
    • M.S. Song, S.J. Song, N.G. Ayad, J.S. Chang, J.H. Lee, and H.K. Hong The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex Nat Cell Biol 6 2004 129 137
    • (2004) Nat Cell Biol , vol.6 , pp. 129-137
    • Song, M.S.1    Song, S.J.2    Ayad, N.G.3    Chang, J.S.4    Lee, J.H.5    Hong, H.K.6
  • 121
    • 33750562135 scopus 로고    scopus 로고
    • Synthesis and screening of N-alkyl hydroxamates for inhibition of cancer cell proliferation
    • K.J. Stanger, D. Sliva, J. Jiang, and V. Krchnak Synthesis and screening of N-alkyl hydroxamates for inhibition of cancer cell proliferation Comb Chem High Throughput Screen 9 2006 651 661
    • (2006) Comb Chem High Throughput Screen , vol.9 , pp. 651-661
    • Stanger, K.J.1    Sliva, D.2    Jiang, J.3    Krchnak, V.4
  • 122
    • 34247376926 scopus 로고    scopus 로고
    • Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities
    • F. Stegmeier, M. Rape, V.M. Draviam, G. Nalepa, M.E. Sowa, and X.L. Ang Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities Nature 446 2007 876 881
    • (2007) Nature , vol.446 , pp. 876-881
    • Stegmeier, F.1    Rape, M.2    Draviam, V.M.3    Nalepa, G.4    Sowa, M.E.5    Ang, X.L.6
  • 123
    • 84892688466 scopus 로고    scopus 로고
    • Expression of cell cycle regulatory factors hus1, gadd45a, rb1, cdkn2a and mre11a correlates with expression of clock gene per2 in human colorectal carcinoma tissue
    • M. Storcelova, M. Vician, R. Reis, M. Zeman, and I. Herichova Expression of cell cycle regulatory factors hus1, gadd45a, rb1, cdkn2a and mre11a correlates with expression of clock gene per2 in human colorectal carcinoma tissue Mol Biol Rep 40 2013 6351 6361
    • (2013) Mol Biol Rep , vol.40 , pp. 6351-6361
    • Storcelova, M.1    Vician, M.2    Reis, R.3    Zeman, M.4    Herichova, I.5
  • 124
    • 45949087615 scopus 로고    scopus 로고
    • Targeting of CDC20 via small interfering RNA causes enhancement of the cytotoxicity of chemoradiation
    • K. Taniguchi, N. Momiyama, M. Ueda, R. Matsuyama, R. Mori, and Y. Fujii Targeting of CDC20 via small interfering RNA causes enhancement of the cytotoxicity of chemoradiation Anticancer Res 28 2008 1559 1563
    • (2008) Anticancer Res , vol.28 , pp. 1559-1563
    • Taniguchi, K.1    Momiyama, N.2    Ueda, M.3    Matsuyama, R.4    Mori, R.5    Fujii, Y.6
  • 125
    • 77951230459 scopus 로고    scopus 로고
    • C-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway
    • C.B. Thien, S.A. Dagger, J.H. Steer, F. Koentgen, E.S. Jansen, and C.L. Scott c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway J Biol Chem 285 2010 10969 10981
    • (2010) J Biol Chem , vol.285 , pp. 10969-10981
    • Thien, C.B.1    Dagger, S.A.2    Steer, J.H.3    Koentgen, F.4    Jansen, E.S.5    Scott, C.L.6
  • 127
    • 6044271376 scopus 로고    scopus 로고
    • Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain
    • R. Verma, N.R. Peters, M. D'Onofrio, G.P. Tochtrop, K.M. Sakamoto, and R. Varadan Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain Science 306 2004 117 120
    • (2004) Science , vol.306 , pp. 117-120
    • Verma, R.1    Peters, N.R.2    D'Onofrio, M.3    Tochtrop, G.P.4    Sakamoto, K.M.5    Varadan, R.6
  • 128
    • 0042921286 scopus 로고    scopus 로고
    • TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1
    • H.C. Vodermaier, C. Gieffers, S. Maurer-Stroh, F. Eisenhaber, and J.M. Peters TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1 Curr Biol 13 2003 1459 1468
    • (2003) Curr Biol , vol.13 , pp. 1459-1468
    • Vodermaier, H.C.1    Gieffers, C.2    Maurer-Stroh, S.3    Eisenhaber, F.4    Peters, J.M.5
  • 129
    • 84901433308 scopus 로고    scopus 로고
    • APC(Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction
    • L. Wan, M. Tan, J. Yang, H. Inuzuka, X. Dai, and T. Wu APC(Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction Dev Cell 29 2014 377 391
    • (2014) Dev Cell , vol.29 , pp. 377-391
    • Wan, L.1    Tan, M.2    Yang, J.3    Inuzuka, H.4    Dai, X.5    Wu, T.6
  • 130
    • 83455195599 scopus 로고    scopus 로고
    • Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1
    • L. Wan, W. Zou, D. Gao, H. Inuzuka, H. Fukushima, and A.H. Berg Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1 Mol Cell 44 2011 721 733
    • (2011) Mol Cell , vol.44 , pp. 721-733
    • Wan, L.1    Zou, W.2    Gao, D.3    Inuzuka, H.4    Fukushima, H.5    Berg, A.H.6
  • 134
    • 84885448500 scopus 로고    scopus 로고
    • Targeting amino acid transport in metastatic castration-resistant prostate cancer: Effects on cell cycle, cell growth, and tumor development
    • Q. Wang, J. Tiffen, C.G. Bailey, M.L. Lehman, W. Ritchie, and L. Fazli Targeting amino acid transport in metastatic castration-resistant prostate cancer: effects on cell cycle, cell growth, and tumor development J Natl Cancer Inst 105 2013 1463 1473
    • (2013) J Natl Cancer Inst , vol.105 , pp. 1463-1473
    • Wang, Q.1    Tiffen, J.2    Bailey, C.G.3    Lehman, M.L.4    Ritchie, W.5    Fazli, L.6
  • 135
    • 84878833718 scopus 로고    scopus 로고
    • Cdc20: A potential novel therapeutic target for cancer treatment
    • Z. Wang, L. Wan, J. Zhong, H. Inuzuka, P. Liu, and F.H. Sarkar Cdc20: a potential novel therapeutic target for cancer treatment Curr Pharm Des 19 2013 3210 3214
    • (2013) Curr Pharm des , vol.19 , pp. 3210-3214
    • Wang, Z.1    Wan, L.2    Zhong, J.3    Inuzuka, H.4    Liu, P.5    Sarkar, F.H.6
  • 136
    • 84923129110 scopus 로고    scopus 로고
    • The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium
    • W. Wang, T. Wu, and M.W. Kirschner The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium eLife 3 2014 e03083
    • (2014) ELife , vol.3 , pp. e03083
    • Wang, W.1    Wu, T.2    Kirschner, M.W.3
  • 137
    • 34547092698 scopus 로고    scopus 로고
    • Cell cycle-dependent expression of centrosomal ninein-like protein in human cells is regulated by the anaphase-promoting complex
    • Y. Wang, and Q. Zhan Cell cycle-dependent expression of centrosomal ninein-like protein in human cells is regulated by the anaphase-promoting complex J Biol Chem 282 2007 17712 17719
    • (2007) J Biol Chem , vol.282 , pp. 17712-17719
    • Wang, Y.1    Zhan, Q.2
  • 138
    • 1642399624 scopus 로고    scopus 로고
    • Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
    • W. Wei, N.G. Ayad, Y. Wan, G.J. Zhang, M.W. Kirschner, and W.G. Kaelin Jr. Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex Nature 428 2004 194 198
    • (2004) Nature , vol.428 , pp. 194-198
    • Wei, W.1    Ayad, N.G.2    Wan, Y.3    Zhang, G.J.4    Kirschner, M.W.5    Kaelin, Jr.W.G.6
  • 139
    • 35148870200 scopus 로고    scopus 로고
    • C-Cbl is not required for ERK1/2-dependent degradation of BimEL
    • C.M. Wiggins, H. Band, and S.J. Cook c-Cbl is not required for ERK1/2-dependent degradation of BimEL Cell Signal 19 2007 2605 2611
    • (2007) Cell Signal , vol.19 , pp. 2605-2611
    • Wiggins, C.M.1    Band, H.2    Cook, S.J.3
  • 140
    • 84878684149 scopus 로고    scopus 로고
    • CDC20 overexpression predicts a poor prognosis for patients with colorectal cancer
    • W.J. Wu, K.S. Hu, D.S. Wang, Z.L. Zeng, D.S. Zhang, and D.L. Chen CDC20 overexpression predicts a poor prognosis for patients with colorectal cancer J Transl Med 11 2013 142
    • (2013) J Transl Med , vol.11 , pp. 142
    • Wu, W.J.1    Hu, K.S.2    Wang, D.S.3    Zeng, Z.L.4    Zhang, D.S.5    Chen, D.L.6
  • 141
    • 84864391525 scopus 로고    scopus 로고
    • Coordinated effects of microRNA-494 induce G 2/M arrest in human cholangiocarcinoma
    • S. Yamanaka, N.R. Campbell, F. An, S.C. Kuo, J.J. Potter, and E. Mezey Coordinated effects of microRNA-494 induce G 2/M arrest in human cholangiocarcinoma Cell Cycle 11 2012
    • (2012) Cell Cycle , vol.11
    • Yamanaka, S.1    Campbell, N.R.2    An, F.3    Kuo, S.C.4    Potter, J.J.5    Mezey, E.6
  • 142
    • 70350514911 scopus 로고    scopus 로고
    • A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation
    • Y. Yang, A.H. Kim, T. Yamada, B. Wu, P.M. Bilimoria, and Y. Ikeuchi A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation Science 326 2009 575 578
    • (2009) Science , vol.326 , pp. 575-578
    • Yang, Y.1    Kim, A.H.2    Yamada, T.3    Wu, B.4    Bilimoria, P.M.5    Ikeuchi, Y.6
  • 143
    • 36049028674 scopus 로고    scopus 로고
    • P31comet blocks Mad2 activation through structural mimicry
    • M. Yang, B. Li, D.R. Tomchick, M. Machius, J. Rizo, and H. Yu p31comet blocks Mad2 activation through structural mimicry Cell 131 2007 744 755
    • (2007) Cell , vol.131 , pp. 744-755
    • Yang, M.1    Li, B.2    Tomchick, D.R.3    Machius, M.4    Rizo, J.5    Yu, H.6
  • 144
    • 84930090723 scopus 로고    scopus 로고
    • Withaferin A inhibits STAT3 and induces tumor cell death in neuroblastoma and multiple myeloma
    • L.P. Yco, G. Mocz, J. Opoku-Ansah, and A.S. Bachmann Withaferin A inhibits STAT3 and induces tumor cell death in neuroblastoma and multiple myeloma Biochem Insights 7 2014 1 13
    • (2014) Biochem Insights , vol.7 , pp. 1-13
    • Yco, L.P.1    Mocz, G.2    Opoku-Ansah, J.3    Bachmann, A.S.4
  • 145
    • 0036902234 scopus 로고    scopus 로고
    • Regulation of APC-Cdc20 by the spindle checkpoint
    • H. Yu Regulation of APC-Cdc20 by the spindle checkpoint Curr Opin Cell Biol 14 2002 706 714
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 706-714
    • Yu, H.1
  • 146
    • 34250799719 scopus 로고    scopus 로고
    • Cdc20: A WD40 activator for a cell cycle degradation machine
    • H. Yu Cdc20: a WD40 activator for a cell cycle degradation machine Mol Cell 27 2007 3 16
    • (2007) Mol Cell , vol.27 , pp. 3-16
    • Yu, H.1
  • 147
    • 31544469559 scopus 로고    scopus 로고
    • Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability
    • B. Yuan, Y. Xu, J.H. Woo, Y. Wang, Y.K. Bae, and D.S. Yoon Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability Clin Cancer Res 12 2006 405 410
    • (2006) Clin Cancer Res , vol.12 , pp. 405-410
    • Yuan, B.1    Xu, Y.2    Woo, J.H.3    Wang, Y.4    Bae, Y.K.5    Yoon, D.S.6
  • 148
    • 79953682249 scopus 로고    scopus 로고
    • Identification of common differentially expressed genes in urinary bladder cancer
    • A. Zaravinos, G.I. Lambrou, I. Boulalas, D. Delakas, and D.A. Spandidos Identification of common differentially expressed genes in urinary bladder cancer PLoS One 6 2011 e18135
    • (2011) PLoS One , vol.6 , pp. e18135
    • Zaravinos, A.1    Lambrou, G.I.2    Boulalas, I.3    Delakas, D.4    Spandidos, D.A.5
  • 149
    • 84858688402 scopus 로고    scopus 로고
    • An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination
    • X. Zeng, and R.W. King An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination Nat Chem Biol 8 2012 383 392
    • (2012) Nat Chem Biol , vol.8 , pp. 383-392
    • Zeng, X.1    King, R.W.2
  • 150
    • 77957947338 scopus 로고    scopus 로고
    • Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage
    • X. Zeng, F. Sigoillot, S. Gaur, S. Choi, K.L. Pfaff, and D.C. Oh Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage Cancer Cell 18 2010 382 395
    • (2010) Cancer Cell , vol.18 , pp. 382-395
    • Zeng, X.1    Sigoillot, F.2    Gaur, S.3    Choi, S.4    Pfaff, K.L.5    Oh, D.C.6
  • 151
    • 47749086687 scopus 로고    scopus 로고
    • RACK1 and CIS mediate the degradation of BimEL in cancer cells
    • W. Zhang, G.Z. Cheng, J. Gong, U. Hermanto, C.S. Zong, and J. Chan RACK1 and CIS mediate the degradation of BimEL in cancer cells J Biol Chem 283 2008 16416 16426
    • (2008) J Biol Chem , vol.283 , pp. 16416-16426
    • Zhang, W.1    Cheng, G.Z.2    Gong, J.3    Hermanto, U.4    Zong, C.S.5    Chan, J.6
  • 152
    • 84921650435 scopus 로고    scopus 로고
    • Gene expression analysis of lung adenocarcinoma and matched adjacent non-tumor lung tissue
    • W. Zhang, W. Gong, H. Ai, J. Tang, and C. Shen Gene expression analysis of lung adenocarcinoma and matched adjacent non-tumor lung tissue Tumori 100 2014 338 345
    • (2014) Tumori , vol.100 , pp. 338-345
    • Zhang, W.1    Gong, W.2    Ai, H.3    Tang, J.4    Shen, C.5
  • 153
    • 84895984956 scopus 로고    scopus 로고
    • Functional characterization of anaphase promoting complex/cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis
    • J. Zhang, L. Wan, X. Dai, Y. Sun, and W. Wei Functional characterization of anaphase promoting complex/cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis Biochim Biophys Acta 1845 2014 277 293
    • (2014) Biochim Biophys Acta , vol.1845 , pp. 277-293
    • Zhang, J.1    Wan, L.2    Dai, X.3    Sun, Y.4    Wei, W.5
  • 154
    • 84916623081 scopus 로고    scopus 로고
    • Potential therapeutic mechanism of genistein in breast cancer involves inhibition of cell cycle regulation
    • L. Zhang, B. Yang, K. Zhou, H. Li, D. Li, and H. Gao Potential therapeutic mechanism of genistein in breast cancer involves inhibition of cell cycle regulation Mol Med Rep 11 2015 1820 1826
    • (2015) Mol Med Rep , vol.11 , pp. 1820-1826
    • Zhang, L.1    Yang, B.2    Zhou, K.3    Li, H.4    Li, D.5    Gao, H.6
  • 155
    • 0035865138 scopus 로고    scopus 로고
    • Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis
    • A. Zur, and M. Brandeis Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis EMBO J 20 2001 792 801
    • (2001) EMBO J , vol.20 , pp. 792-801
    • Zur, A.1    Brandeis, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.