BimEL is phosphorylated at mitosis by Aurora A and targeted for degradation by βtrCP1

Cell Death and Differentiation

Volumn 20, Issue 10, 2013, Pages 1393-1403

  Moustafa Kamal, M ^a,b   Gamache, I ^a   Lu, Y ^a,b   Li, S ^b   Teodoro, J G ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

apoptosis; aurora kinase; cell cycle; mitosis

Indexed keywords

4 [[9 CHLORO 7 (2,6 DIFLUOROPHENYL) 5H PYRIMIDO[5,4 D][2]BENZAZEPIN 2 YL]AMINO]BENZOIC ACID; AURORA A KINASE; BETA TRANSDUCIN REPEAT CONTAINING E3 UBIQUITIN PROTEIN LIGASE 1; BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; BIM PROTEIN; F BOX PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2A; SERINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; MITOSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REGULATORY MECHANISM; UBIQUITINATION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AURORA KINASE A; BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; M PHASE CELL CYCLE CHECKPOINTS; MEMBRANE PROTEINS; MITOSIS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; TRANSFECTION; UBIQUITINATION;

EID: 84883781728     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2013.93     Document Type: Article

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