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Volumn 9, Issue 19, 2010, Pages 3904-3912

APC/C-Cdh1: From cell cycle to cellular differentiation and genomic integrity

Author keywords

APC C; Cdh1; Differentiation; Genomic integrity; Proteolysis; Signal transduction; Tumorigenesis

Indexed keywords

ANAPHASE PROMOTING COMPLEX; RAS PROTEIN; RETINOBLASTOMA PROTEIN; UVOMORULIN;

EID: 77958465476     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.19.13585     Document Type: Review
Times cited : (79)

References (75)
  • 1
    • 70549088824 scopus 로고    scopus 로고
    • The function of APC/CCdh1 in cell cycle and beyond
    • Li M, Zhang P. The function of APC/CCdh1 in cell cycle and beyond. Cell Div 2009; 4:2.
    • (2009) Cell Div , vol.4 , pp. 2
    • Li, M.1    Zhang, P.2
  • 2
    • 33747589184 scopus 로고    scopus 로고
    • The anaphase promoting complex/cyclosome: A machine designed to destroy
    • Peters JM. The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat Rev Mol Cell Biol 2006; 7:2-4.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 2-4
    • Peters, J.M.1
  • 3
    • 0030693087 scopus 로고    scopus 로고
    • CDC20 and CDH1: A family of substrate-specific activators of APC- Dependent proteolysis
    • DOI 10.1126/science.278.5337.460
    • Visintin R, Prinz S, Amon A. CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science 1997; 278:460-3. (Pubitemid 27454429)
    • (1997) Science , vol.278 , Issue.5337 , pp. 460-463
    • Visintin, R.1    Prinz, S.2    Amon, A.3
  • 6
    • 73849129220 scopus 로고    scopus 로고
    • The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression
    • Wasch R, Robbins JA, Cross FR. The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression. Oncogene 2010; 29:1-10.
    • (2010) Oncogene , vol.29 , pp. 1-10
    • Wasch, R.1    Robbins, J.A.2    Cross, F.R.3
  • 7
    • 77952586024 scopus 로고    scopus 로고
    • Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress
    • Zhang L, Park CH, Wu J, Kim H, Liu W, Fujita T, et al. Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress. EMBO J 2010; 29:1726-37.
    • (2010) EMBO J , vol.29 , pp. 1726-1737
    • Zhang, L.1    Park, C.H.2    Wu, J.3    Kim, H.4    Liu, W.5    Fujita, T.6
  • 8
    • 67749145231 scopus 로고    scopus 로고
    • Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways
    • Gao D, Inuzuka H, Korenjak M, Tseng A, Wu T, Wan L, et al. Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways. Mol Biol Cell 2009; 20:3305-16.
    • (2009) Mol Biol Cell , vol.20 , pp. 3305-3316
    • Gao, D.1    Inuzuka, H.2    Korenjak, M.3    Tseng, A.4    Wu, T.5    Wan, L.6
  • 9
    • 23944450180 scopus 로고    scopus 로고
    • Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability
    • Ke PY, Kuo YY, Hu CM, Chang ZF. Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability. Genes Dev 2005; 19:1920-33.
    • (2005) Genes Dev , vol.19 , pp. 1920-1933
    • Ke, P.Y.1    Kuo, Y.Y.2    Hu, C.M.3    Chang, Z.F.4
  • 12
    • 0031055137 scopus 로고    scopus 로고
    • APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle
    • DOI 10.1126/science.275.5304.1311
    • Juang YL, Huang J, Peters JM, McLaughlin ME, Tai CY, Pellman D. APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle. Science 1997; 275:1311-4. (Pubitemid 27114160)
    • (1997) Science , vol.275 , Issue.5304 , pp. 1311-1314
    • Juang, Y.-L.1    Huang, J.2    Peters, J.-M.3    McLaughlin, M.E.4    Tai, C.-Y.5    Pellman, D.6
  • 13
    • 39149089275 scopus 로고    scopus 로고
    • Polo and Aurora kinases: Lessons derived from chemical biology
    • Taylor S, Peters JM. Polo and Aurora kinases: lessons derived from chemical biology. Curr Opin Cell Biol 2008; 20:77-84.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 77-84
    • Taylor, S.1    Peters, J.M.2
  • 14
    • 35948951997 scopus 로고    scopus 로고
    • The dual effects of Cdh1/APC in myogenesis
    • Li W, Wu G, Wan Y. The dual effects of Cdh1/APC in myogenesis. FASEB J 2007; 21:3606-17.
    • (2007) FASEB J , vol.21 , pp. 3606-3617
    • Li, W.1    Wu, G.2    Wan, Y.3
  • 16
    • 38949099707 scopus 로고    scopus 로고
    • Cdh1 is required to maintain genome integrity in primary human cells
    • DOI 10.1038/sj.onc.1210703, PII 1210703
    • Engelbert D, Schnerch D, Baumgarten A, Wasch R. The ubiquitin ligase APC(Cdh1) is required to maintain genome integrity in primary human cells. Oncogene 2008; 27:907-17. (Pubitemid 351225382)
    • (2008) Oncogene , vol.27 , Issue.7 , pp. 907-917
    • Engelbert, D.1    Schnerch, D.2    Baumgarten, A.3    Wasch, R.4
  • 17
    • 0034717570 scopus 로고    scopus 로고
    • Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex
    • Rudner AD, Murray AW. Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex. J Cell Biol 2000; 149:1377-90.
    • (2000) J Cell Biol , vol.149 , pp. 1377-1390
    • Rudner, A.D.1    Murray, A.W.2
  • 18
    • 34247333444 scopus 로고    scopus 로고
    • The spindle-assembly checkpoint in space and time
    • Musacchio A, Salmon ED. The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol 2007; 8:379-93.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 379-393
    • Musacchio, A.1    Salmon, E.D.2
  • 19
    • 49849098630 scopus 로고    scopus 로고
    • Regulation of APC/C activators in mitosis and meiosis
    • Pesin JA, Orr-Weaver TL. Regulation of APC/C activators in mitosis and meiosis. Annu Rev Cell Dev Biol 2008; 24:475-99.
    • (2008) Annu Rev Cell Dev Biol , vol.24 , pp. 475-499
    • Pesin, J.A.1    Orr-Weaver, T.L.2
  • 20
    • 44649084365 scopus 로고    scopus 로고
    • Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle
    • DOI 10.1038/ncb1729, PII NCB1729
    • Crasta K, Lim HH, Giddings TH Jr, Winey M, Surana U. Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle. Nat Cell Biol 2008; 10:665-75. (Pubitemid 351772932)
    • (2008) Nature Cell Biology , vol.10 , Issue.6 , pp. 665-675
    • Crasta, K.1    Lim, H.H.2    Giddings Jr., T.H.3    Winey, M.4    Surana, U.5
  • 21
    • 0032573374 scopus 로고    scopus 로고
    • Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex
    • Zachariae W, Schwab M, Nasmyth K, Seufert W. Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex. Science 1998; 282:1721-4. (Pubitemid 28549290)
    • (1998) Science , vol.282 , Issue.5394 , pp. 1721-1724
    • Zachariae, W.1    Schwab, M.2    Nasmyth, K.3    Seufert, W.4
  • 22
    • 0034654399 scopus 로고    scopus 로고
    • The KEN box: An APC recognition signal distinct from the D box targeted by Cdh1
    • Pfleger CM, Kirschner MW. The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1. Genes Dev 2000; 14:655-65.
    • (2000) Genes Dev , vol.14 , pp. 655-665
    • Pfleger, C.M.1    Kirschner, M.W.2
  • 23
    • 25844499804 scopus 로고    scopus 로고
    • Anillin is a substrate of anaphase-promoting complex/cyclosome (APC/C) that controls spatial contractility of myosin during late cytokinesis
    • DOI 10.1074/jbc.M504657200
    • Zhao WM, Fang G. Anillin is a substrate of anaphase-promoting complex/cyclosome (APC/C) that controls spatial contractility of myosin during late cytokinesis. J Biol Chem 2005; 280:33516-24. (Pubitemid 41397151)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.39 , pp. 33516-33524
    • Zhao, W.-M.1    Fang, G.2
  • 24
    • 27944458407 scopus 로고    scopus 로고
    • Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit
    • DOI 10.1128/MCB.25.23.10516-10527.2005
    • Stewart S, Fang G. Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit. Mol Cell Biol 2005; 25:10516-27. (Pubitemid 41681972)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.23 , pp. 10516-10527
    • Stewart, S.1    Fang, G.2
  • 26
    • 51049088378 scopus 로고    scopus 로고
    • The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory
    • Li M, Shin YH, Hou L, Huang X, Wei Z, Klann E, et al. The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory. Nat Cell Biol 2008; 10:1083-9.
    • (2008) Nat Cell Biol , vol.10 , pp. 1083-1089
    • Li, M.1    Shin, Y.H.2    Hou, L.3    Huang, X.4    Wei, Z.5    Klann, E.6
  • 28
    • 0033578073 scopus 로고    scopus 로고
    • p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27
    • Tsvetkov LM, Yeh KH, Lee SJ, Sun H, Zhang H. p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27. Curr Biol 1999; 9:661-4.
    • (1999) Curr Biol , vol.9 , pp. 661-664
    • Tsvetkov, L.M.1    Yeh, K.H.2    Lee, S.J.3    Sun, H.4    Zhang, H.5
  • 29
    • 0028970609 scopus 로고
    • Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions
    • Albanese C, Johnson J, Watanabe G, Eklund N, Vu D, Arnold A, et al. Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions. J Biol Chem 1995; 270:23589-97.
    • (1995) J Biol Chem , vol.270 , pp. 23589-23597
    • Albanese, C.1    Johnson, J.2    Watanabe, G.3    Eklund, N.4    Vu, D.5    Arnold, A.6
  • 30
    • 4544221279 scopus 로고    scopus 로고
    • Regulation of early events in chromosome replication
    • Diffley JF. Regulation of early events in chromosome replication. Curr Biol 2004; 14:778-86.
    • (2004) Curr Biol , vol.14 , pp. 778-786
    • Diffley, J.F.1
  • 31
    • 0032511148 scopus 로고    scopus 로고
    • Geminin, an inhibitor of DNA replication, is degraded during mitosis
    • McGarry TJ, Kirschner MW. Geminin, an inhibitor of DNA replication, is degraded during mitosis. Cell 1998; 93:1043-53.
    • (1998) Cell , vol.93 , pp. 1043-1053
    • McGarry, T.J.1    Kirschner, M.W.2
  • 33
    • 0033796454 scopus 로고    scopus 로고
    • Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis
    • Sorensen CS, Lukas C, Kramer ER, Peters JM, Bartek J, Lukas J. Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis. Mol Cell Biol 2000; 20:7613-23.
    • (2000) Mol Cell Biol , vol.20 , pp. 7613-7623
    • Sorensen, C.S.1    Lukas, C.2    Kramer, E.R.3    Peters, J.M.4    Bartek, J.5    Lukas, J.6
  • 36
    • 0033592688 scopus 로고    scopus 로고
    • Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex
    • Lukas C, Sorensen CS, Kramer E, Santoni-Rugiu E, Lindeneg C, Peters JM, et al. Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex. Nature 1999; 401:815-8.
    • (1999) Nature , vol.401 , pp. 815-818
    • Lukas, C.1    Sorensen, C.S.2    Kramer, E.3    Santoni-Rugiu, E.4    Lindeneg, C.5    Peters, J.M.6
  • 37
    • 25444517778 scopus 로고    scopus 로고
    • Involvement of the SCF complex in the control of Cdh1 degradation in S-phase
    • Benmaamar R, Pagano M. Involvement of the SCF complex in the control of Cdh1 degradation in S-phase. Cell Cycle 2005; 4:1230-2. (Pubitemid 41365394)
    • (2005) Cell Cycle , vol.4 , Issue.9 , pp. 1230-1232
    • Benmaamar, R.1    Pagano, M.2
  • 38
    • 10344247126 scopus 로고    scopus 로고
    • Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry
    • DOI 10.1038/nature03023
    • Rape M, Kirschner MW. Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry. Nature 2004; 432:588-95. (Pubitemid 39626259)
    • (2004) Nature , vol.432 , Issue.7017 , pp. 588-595
    • Rape, M.1    Kirschner, M.W.2
  • 39
    • 30344466977 scopus 로고    scopus 로고
    • The processivity of multiubiquitination by the APC determines the order of substrate degradation
    • DOI 10.1016/j.cell.2005.10.032, PII S0092867405012328
    • Rape M, Reddy SK, Kirschner MW. The processivity of multiubiquitination by the APC determines the order of substrate degradation. Cell 2006; 124:89-103. (Pubitemid 43069312)
    • (2006) Cell , vol.124 , Issue.1 , pp. 89-103
    • Rape, M.1    Reddy, S.K.2    Kirschner, M.W.3
  • 41
    • 40549083014 scopus 로고    scopus 로고
    • Proteolysis of CDH1 enhances susceptibility to UV radiation-induced apoptosis
    • DOI 10.1093/carcin/bgm251
    • Liu W, Li W, Fujita T, Yang Q, Wan Y. Proteolysis of CDH1 enhances susceptibility to UV radiation-induced apoptosis. Carcinogenesis 2008; 29:263-72. (Pubitemid 351359664)
    • (2008) Carcinogenesis , vol.29 , Issue.2 , pp. 263-272
    • Liu, W.1    Li, W.2    Fujita, T.3    Yang, Q.4    Wan, Y.5
  • 42
    • 33746408535 scopus 로고    scopus 로고
    • Rad17 Phosphorylation Is Required for Claspin Recruitment and Chk1 Activation in Response to Replication Stress
    • DOI 10.1016/j.molcel.2006.06.022, PII S1097276506004497
    • Wang X, Zou L, Lu T, Bao S, Hurov KE, Hittelman WN, et al. Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress. Mol Cell 2006; 23:331-41. (Pubitemid 44128854)
    • (2006) Molecular Cell , vol.23 , Issue.3 , pp. 331-341
    • Wang, X.1    Zou, L.2    Lu, T.3    Bao, S.4    Hurov, K.E.5    Hittelman, W.N.6    Elledge, S.J.7    Li, L.8
  • 43
    • 3242878502 scopus 로고    scopus 로고
    • Claspin, a regulator of Chk1 in DNA replication stress pathway
    • DOI 10.1016/j.dnarep.2004.03.001, PII S1568786404000606
    • Chini CC, Chen J. Claspin, a regulator of Chk1 in DNA replication stress pathway. DNA Repair (Amst) 2004; 3:1033-7. (Pubitemid 38997945)
    • (2004) DNA Repair , vol.3 , Issue.8-9 , pp. 1033-1037
    • Chini, C.C.S.1    Chen, J.2
  • 45
    • 3042687608 scopus 로고    scopus 로고
    • Deregulation of cyclin e in human cells interferes with prereplication complex assembly
    • DOI 10.1083/jcb.200404092
    • Ekholm-Reed S, Mendez J, Tedesco D, Zetterberg A, Stillman B, Reed SI. Deregulation of cyclin E in human cells interferes with prereplication complex assembly. J Cell Biol 2004; 165:789-800. (Pubitemid 38821970)
    • (2004) Journal of Cell Biology , vol.165 , Issue.6 , pp. 789-800
    • Ekholm-Reed, S.1    Mendez, J.2    Tedesco, D.3    Zetterberg, A.4    Stillman, B.5    Reed, S.I.6
  • 46
    • 77953810029 scopus 로고    scopus 로고
    • 2 is part of the long-term response to genotoxic stress
    • 2 is part of the long-term response to genotoxic stress. Oncogene 2010; 29:3477-89.
    • (2010) Oncogene , vol.29 , pp. 3477-3489
    • Wiebusch, L.1    Hagemeier, C.2
  • 47
    • 30744477013 scopus 로고    scopus 로고
    • The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation
    • DOI 10.1038/nature04221, PII NATURE04221
    • Jeganathan KB, Malureanu L, van Deursen JM. The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation. Nature 2005; 438:1036-9. (Pubitemid 43093978)
    • (2005) Nature , vol.438 , Issue.7070 , pp. 1036-1039
    • Jeganathan, K.B.1    Malureanu, L.2    Van Deursen, J.M.3
  • 48
    • 59449104804 scopus 로고    scopus 로고
    • Multiple anaphase-promoting complex/cyclosome degrons mediate the degradation of human Sgo1
    • Karamysheva Z, Diaz-Martinez LA, Crow SE, Li B, Yu H. Multiple anaphase-promoting complex/cyclosome degrons mediate the degradation of human Sgo1. J Biol Chem 2009; 284:1772-80.
    • (2009) J Biol Chem , vol.284 , pp. 1772-1780
    • Karamysheva, Z.1    Diaz-Martinez, L.A.2    Crow, S.E.3    Li, B.4    Yu, H.5
  • 49
    • 33645225290 scopus 로고    scopus 로고
    • Securin associates with APCCdh1 in prometaphase but its destruction is delayed by Rae1 and Nup98 until the metaphase/anaphase transition
    • Jeganathan KB, Baker DJ, van Deursen JM. Securin associates with APCCdh1 in prometaphase but its destruction is delayed by Rae1 and Nup98 until the metaphase/anaphase transition. Cell Cycle 2006; 5:366-70.
    • (2006) Cell Cycle , vol.5 , pp. 366-370
    • Jeganathan, K.B.1    Baker, D.J.2    Van Deursen, J.M.3
  • 50
    • 33748286796 scopus 로고    scopus 로고
    • A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
    • DOI 10.1038/ng1861, PII NG1861
    • Carter SL, Eklund AC, Kohane IS, Harris LN, Szallasi Z. A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. Nat Genet 2006; 38:1043-8. (Pubitemid 44325930)
    • (2006) Nature Genetics , vol.38 , Issue.9 , pp. 1043-1048
    • Carter, S.L.1    Eklund, A.C.2    Kohane, I.S.3    Harris, L.N.4    Szallasi, Z.5
  • 51
    • 77950932096 scopus 로고    scopus 로고
    • Persistent telomere damage induces bypass of mitosis and tetraploidy
    • Davoli T, Denchi EL, de Lange T. Persistent telomere damage induces bypass of mitosis and tetraploidy. Cell 2010; 141:81-93.
    • (2010) Cell , vol.141 , pp. 81-93
    • Davoli, T.1    Denchi, E.L.2    De Lange, T.3
  • 52
    • 0035930333 scopus 로고    scopus 로고
    • The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction
    • DOI 10.1016/S1097-2765(01)00382-3
    • Wan Y, Liu X, Kirschner MW. The anaphase-promoting complex mediates TGFbeta signaling by targeting SnoN for destruction. Mol Cell 2001; 8:1027-39. (Pubitemid 34031805)
    • (2001) Molecular Cell , vol.8 , Issue.5 , pp. 1027-1039
    • Wan, Y.1    Liu, X.2    Kirschner, M.W.3
  • 53
    • 0035498980 scopus 로고    scopus 로고
    • Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN
    • Stroschein SL, Bonni S, Wrana JL, Luo K. Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN. Genes Dev 2001; 15:2822-36. (Pubitemid 33042053)
    • (2001) Genes and Development , vol.15 , Issue.21 , pp. 2822-2836
    • Stroschein, S.L.1    Bonni, S.2    Wrana, J.L.3    Luo, K.4
  • 54
    • 34147213257 scopus 로고    scopus 로고
    • Cdh1-anaphase-promoting complex targets Skp2 for destruction in transforming growth factor beta-induced growth inhibition
    • DOI 10.1128/MCB.01830-06
    • Liu W, Wu G, Li W, Lobur D, Wan Y. Cdh1-anaphase-promoting complex targets Skp2 for destruction in transforming growth factor beta-induced growth inhibition. Mol Cell Biol 2007; 27:2967-79. (Pubitemid 46581310)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.8 , pp. 2967-2979
    • Liu, W.1    Wu, G.2    Li, W.3    Lobur, D.4    Wan, Y.5
  • 55
    • 1642330518 scopus 로고    scopus 로고
    • Notch-dependent fizzy-related/Hec1/Cdh1 expression is required for the mitotic-to-endocycle transition in Drosophila follicle cells
    • DOI 10.1016/j.cub.2004.03.040, PII S096098220400212X
    • Schaeffer V, Althauser C, Shcherbata HR, Deng WM, Ruohola-Baker H. Notch-dependent Fizzy-related/Hec1/Cdh1 expression is required for the mitotic-toendocycle transition in Drosophila follicle cells. Curr Biol 2004; 14:630-6. (Pubitemid 38458954)
    • (2004) Current Biology , vol.14 , Issue.7 , pp. 630-636
    • Schaeffer, V.1    Althauser, C.2    Shcherbata, H.R.3    Deng, W.-M.4    Ruohola-Baker, H.5
  • 58
    • 0034235317 scopus 로고    scopus 로고
    • Overexpression of murine fizzy-related (fzr) increases natural killer cell-mediated cell death and suppresses tumor growth
    • Wang CX, Fisk BC, Wadehra M, Su H, Braun J. Overexpression of murine fizzy-related (fzr) increases natural killer cell-mediated cell death and suppresses tumor growth. Blood 2000; 96:259-63. (Pubitemid 30456479)
    • (2000) Blood , vol.96 , Issue.1 , pp. 259-263
    • Wang, C.-X.1    Fisk, B.C.2    Wadehra, M.3    Su, H.4    Braun, J.5
  • 60
  • 62
    • 39749174970 scopus 로고    scopus 로고
    • TGFbeta-Smad2 signaling regulates the Cdh1-APC/SnoN pathway of axonal morphogenesis
    • DOI 10.1523/JNEUROSCI.3061-07.2008
    • Stegmuller J, Huynh MA, Yuan Z, Konishi Y, Bonni A. TGFbeta-Smad2 signaling regulates the Cdh1-APC/SnoN pathway of axonal morphogenesis. J Neurosci 2008; 28:1961-9. (Pubitemid 351302668)
    • (2008) Journal of Neuroscience , vol.28 , Issue.8 , pp. 1961-1969
    • Stegmuller, J.1    Huynh, M.A.2    Yuan, Z.3    Konishi, Y.4    Bonni, A.5
  • 64
    • 44349121372 scopus 로고    scopus 로고
    • Cdh1 activation and neuroblastoma SH-SY5Y differentiation
    • DOI 10.1038/sj.onc.1210987, PII 1210987
    • Cuende J, Moreno S, Bolanos JP, Almeida A. Retinoic acid downregulates Rae1 leading to APC(Cdh1) activation and neuroblastoma SH-SY5Y differentiation. Oncogene 2008; 27:3339-44. (Pubitemid 351733387)
    • (2008) Oncogene , vol.27 , Issue.23 , pp. 3339-3344
    • Cuende, J.1    Moreno, S.2    Bolanos, J.P.3    Almeida, A.4
  • 65
    • 23144464750 scopus 로고    scopus 로고
    • Id family of helix-loophelix proteins in cancer
    • Perk J, Iavarone A, Benezra R. Id family of helix-loophelix proteins in cancer. Nat Rev Cancer 2005; 5:603-14.
    • (2005) Nat Rev Cancer , vol.5 , pp. 603-614
    • Perk, J.1    Iavarone, A.2    Benezra, R.3
  • 67
    • 67650071232 scopus 로고    scopus 로고
    • An in vivo study of Cdh1/APC in breast cancer formation
    • Fujita T, Liu W, Doihara H, Wan Y. An in vivo study of Cdh1/APC in breast cancer formation. Int J Cancer 2009; 125:826-36.
    • (2009) Int J Cancer , vol.125 , pp. 826-836
    • Fujita, T.1    Liu, W.2    Doihara, H.3    Wan, Y.4
  • 68
    • 42249100316 scopus 로고    scopus 로고
    • Cdh1-Skp2 cascade in breast cancer
    • DOI 10.1158/1078-0432.CCR-07-1585
    • Fujita T, Liu W, Doihara H, Date H, Wan Y. Dissection of the APCCdh1-Skp2 cascade in breast cancer. Clin Cancer Res 2008; 14:1966-75. (Pubitemid 351551105)
    • (2008) Clinical Cancer Research , vol.14 , Issue.7 , pp. 1966-1975
    • Fujita, T.1    Liu, W.2    Doihara, H.3    Date, H.4    Wan, Y.5
  • 69
    • 46749127419 scopus 로고    scopus 로고
    • Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis
    • DOI 10.2353/ajpath.2008.070957
    • Fujita T, Liu W, Doihara H, Wan Y. Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis. Am J Pathol 2008; 173:217-28. (Pubitemid 351947969)
    • (2008) American Journal of Pathology , vol.173 , Issue.1 , pp. 217-228
    • Fujita, T.1    Liu, W.2    Doihara, H.3    Wan, Y.4
  • 70
    • 34547137412 scopus 로고    scopus 로고
    • Skp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas
    • DOI 10.1182/blood-2006-11-060350
    • Lwin T, Hazlehurst LA, Dessureault S, Lai R, Bai W, Sotomayor E, et al. Cell adhesion induces p27Kip1-associated cell cycle arrest through downregulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas. Blood 2007; 110:1631-8. (Pubitemid 47443981)
    • (2007) Blood , vol.110 , Issue.5 , pp. 1631-1638
    • Lwin, T.1    Hazlehurst, L.A.2    Dessureault, S.3    Lai, R.4    Bai, W.5    Sotomayor, E.6    Moscinski, L.C.7    Dalton, W.S.8    Tao, J.9
  • 71
    • 0037011124 scopus 로고    scopus 로고
    • Cdh1
    • DOI 10.1093/emboj/cdf634
    • Jaquenoud M, van Drogen F, Peter M. Cell cycle-dependent nuclear export of Cdh1p may contribute to the inactivation of APC/C(Cdh1). EMBO J 2002; 21:6515-26. (Pubitemid 35448429)
    • (2002) EMBO Journal , vol.21 , Issue.23 , pp. 6515-6526
    • Jaquenoud, M.1    Van Drogen, F.2    Peter, M.3
  • 72
    • 13944267882 scopus 로고    scopus 로고
    • Multi-kinase phosphorylation of the APC/C activator Cdh1 revealed by mass spectrometry
    • Hall MC, Warren EN, Borchers CH. Multi-kinase phosphorylation of the APC/C activator Cdh1 revealed by mass spectrometry. Cell Cycle 2004; 3:1278-84.
    • (2004) Cell Cycle , vol.3 , pp. 1278-1284
    • Hall, M.C.1    Warren, E.N.2    Borchers, C.H.3
  • 73
    • 67650938988 scopus 로고    scopus 로고
    • Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1
    • Gao D, Inuzuka H, Tseng A, Wei W. Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1. Cell Div 2009; 4:11.
    • (2009) Cell Div , vol.4 , pp. 11
    • Gao, D.1    Inuzuka, H.2    Tseng, A.3    Wei, W.4
  • 74
    • 41549087914 scopus 로고    scopus 로고
    • Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer
    • Kitajima S, Kudo Y, Ogawa I, Tatsuka M, Kawai H, Pagano M, et al. Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer. PLoS One 2007; 2:944.
    • (2007) PLoS One , vol.2 , pp. 944
    • Kitajima, S.1    Kudo, Y.2    Ogawa, I.3    Tatsuka, M.4    Kawai, H.5    Pagano, M.6
  • 75
    • 33751232623 scopus 로고    scopus 로고
    • Role of L2DTL, cell cycle-regulated nuclear and centrosome protein, in aggressive hepatocellular carcinoma
    • Pan HW, Chou HY, Liu SH, Peng SY, Liu CL, Hsu HC. Role of L2DTL, cell cycle-regulated nuclear and centrosome protein, in aggressive hepatocellular carcinoma. Cell Cycle 2006; 5:2676-87.
    • (2006) Cell Cycle , vol.5 , pp. 2676-2687
    • Pan, H.W.1    Chou, H.Y.2    Liu, S.H.3    Peng, S.Y.4    Liu, C.L.5    Hsu, H.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.