APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box

EMBO Journal

Volumn 20, Issue 24, 2001, Pages 7117-7127

  Hames, Rebecca S ^a,d   Wattam, Samantha L ^a,d   Yamano, Hiroyuki ^b   Bacchieri, Rachid ^a,c   Fry, Andrew M ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d CNRS   (France)

Author keywords

APC; Cdc20; Centrosome; Cyclin A; Nek2

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CYCLIN A; NEK2A KINASE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL LINE; CENTROSOME; DNA STRUCTURE; ENZYME ACTIVITY; ENZYME DEGRADATION; GENE DELETION; GENE MUTATION; HUMAN; HUMAN CELL; MITOSIS; MITOSIS SPINDLE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; REACTION ANALYSIS;

AMINO ACID SEQUENCE; CYCLIN A; CYSTEINE ENDOPEPTIDASES; HUMANS; LIGASES; MITOSIS; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; TUMOR CELLS, CULTURED; UBIQUITIN;

EID: 0037126610     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.24.7117     Document Type: Article

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